JP2019521695A5 - - Google Patents

Download PDF

Info

Publication number
JP2019521695A5
JP2019521695A5 JP2019504715A JP2019504715A JP2019521695A5 JP 2019521695 A5 JP2019521695 A5 JP 2019521695A5 JP 2019504715 A JP2019504715 A JP 2019504715A JP 2019504715 A JP2019504715 A JP 2019504715A JP 2019521695 A5 JP2019521695 A5 JP 2019521695A5
Authority
JP
Japan
Prior art keywords
viral
gene
biological sample
rna
days
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2019504715A
Other languages
English (en)
Japanese (ja)
Other versions
JP7483373B2 (ja
JP2019521695A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/044550 external-priority patent/WO2018023094A1/en
Publication of JP2019521695A publication Critical patent/JP2019521695A/ja
Publication of JP2019521695A5 publication Critical patent/JP2019521695A5/ja
Priority to JP2022109066A priority Critical patent/JP2022130714A/ja
Application granted granted Critical
Publication of JP7483373B2 publication Critical patent/JP7483373B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2019504715A 2016-07-29 2017-07-28 複製可能ウイルスの存在または非存在を評価するための方法 Active JP7483373B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022109066A JP2022130714A (ja) 2016-07-29 2022-07-06 複製可能ウイルスの存在または非存在を評価するための方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662369024P 2016-07-29 2016-07-29
US62/369,024 2016-07-29
US201762448954P 2017-01-20 2017-01-20
US62/448,954 2017-01-20
PCT/US2017/044550 WO2018023094A1 (en) 2016-07-29 2017-07-28 Methods for assessing the presence or absence of replication competent virus

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022109066A Division JP2022130714A (ja) 2016-07-29 2022-07-06 複製可能ウイルスの存在または非存在を評価するための方法

Publications (3)

Publication Number Publication Date
JP2019521695A JP2019521695A (ja) 2019-08-08
JP2019521695A5 true JP2019521695A5 (enExample) 2020-09-03
JP7483373B2 JP7483373B2 (ja) 2024-05-15

Family

ID=59656184

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019504715A Active JP7483373B2 (ja) 2016-07-29 2017-07-28 複製可能ウイルスの存在または非存在を評価するための方法
JP2022109066A Pending JP2022130714A (ja) 2016-07-29 2022-07-06 複製可能ウイルスの存在または非存在を評価するための方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022109066A Pending JP2022130714A (ja) 2016-07-29 2022-07-06 複製可能ウイルスの存在または非存在を評価するための方法

Country Status (10)

Country Link
US (2) US11421287B2 (enExample)
EP (1) EP3491152B1 (enExample)
JP (2) JP7483373B2 (enExample)
CN (1) CN109804089A (enExample)
AU (1) AU2017301881A1 (enExample)
CA (1) CA3031994A1 (enExample)
ES (1) ES2926513T3 (enExample)
MA (1) MA45783A (enExample)
MX (1) MX2019001186A (enExample)
WO (1) WO2018023094A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111918972A (zh) * 2018-01-31 2020-11-10 朱诺治疗学股份有限公司 评估存在或不存在有复制能力的病毒的方法和试剂
CN112367973A (zh) 2018-05-15 2021-02-12 旗舰先锋创新V股份有限公司 融合剂脂质体组合物和其用途
CA3105953A1 (en) 2018-07-09 2020-01-16 Flagship Pioneering Innovations V, Inc. Fusosome compositions and uses thereof
EP3880179A2 (en) 2018-11-14 2021-09-22 Flagship Pioneering Innovations V, Inc. Fusosome compositions for cns delivery
WO2020102503A2 (en) 2018-11-14 2020-05-22 Flagship Pioneering Innovations V, Inc. Fusosome compositions for t cell delivery
US20230048166A1 (en) 2018-11-14 2023-02-16 Flagship Pioneering Innovations V, Inc. Fusosome compositions for hematopoietic stem cell delivery
CN111910015A (zh) * 2019-05-08 2020-11-10 深圳宾德生物技术有限公司 一种检测复制型慢病毒的探针、引物对、荧光定量pcr试剂盒及方法
US12152281B2 (en) * 2019-05-30 2024-11-26 Trizell Ltd. Gene therapy vector contamination assay
EP4025698A1 (en) 2019-09-03 2022-07-13 Sana Biotechnology, Inc. Cd24-associated particles and related methods and uses thereof
CN115003818A (zh) * 2020-01-22 2022-09-02 科济生物医药(上海)有限公司 病毒载体转导细胞的方法
GB202003412D0 (en) * 2020-03-09 2020-04-22 Oxford Biomedica Ltd Replication competent virus assay
CN111647576B (zh) * 2020-06-24 2021-02-09 南京诺唯赞生物科技股份有限公司 一种热稳定性逆转录酶突变体及其应用
CN112280896A (zh) * 2020-09-30 2021-01-29 浙江大学 一种基于微滴式数字pcr技术的乙型肝炎病毒t216c突变检测方法
KR20230151513A (ko) 2021-01-11 2023-11-01 사나 바이오테크놀로지, 인크. Cd8 표적 바이러스 벡터의 용도
CN112877474A (zh) * 2021-02-19 2021-06-01 北京鼎成肽源生物技术有限公司 一种检测慢病毒介导的基因修饰细胞中复制型病毒的引物组、试剂盒及方法
CN113264989A (zh) * 2021-05-17 2021-08-17 吉林大学 一种h9n2亚型禽流感嵌合病毒样颗粒制备方法及应用
EP4381081A1 (en) 2021-08-04 2024-06-12 Sana Biotechnology, Inc. Use of cd4-targeted viral vectors
CN113699278A (zh) * 2021-09-17 2021-11-26 深圳因诺免疫有限公司 一种基于q-PCR法检测复制型逆转录病毒的引物、试剂盒及检测方法
US20250082777A1 (en) 2022-01-10 2025-03-13 Sana Biotechnology, Inc. Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
WO2023150518A1 (en) 2022-02-01 2023-08-10 Sana Biotechnology, Inc. Cd3-targeted lentiviral vectors and uses thereof
WO2023150647A1 (en) 2022-02-02 2023-08-10 Sana Biotechnology, Inc. Methods of repeat dosing and administration of lipid particles or viral vectors and related systems and uses
US20260027145A1 (en) 2022-07-27 2026-01-29 Sana Biotechnology, Inc. Methods of transduction using a viral vector and inhibitors of antiviral restriction factors
CN119530449A (zh) * 2023-08-31 2025-02-28 上海恒润达生生物科技股份有限公司 复制型逆转录病毒检测引物及方法
CN117737303A (zh) * 2023-12-14 2024-03-22 浙江恒驭生物科技有限公司 细胞治疗产品中复制型逆转录病毒rcr-galv的检测组合物、方法及试剂盒
WO2026008886A1 (en) * 2024-07-05 2026-01-08 Immatics Biotechnologies Gmbh Means and methods for the quantification of target expression
CN118465261B (zh) * 2024-07-09 2024-10-15 浙江康佰裕生物科技有限公司 一种检测逆转录病毒载体物理滴度的elisa试剂盒
CN118459577B (zh) * 2024-07-09 2024-11-12 浙江康佰裕生物科技有限公司 逆转录包膜蛋白GALV env蛋白及其抗体的制备

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452773A (en) 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4795698A (en) 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
US4996143A (en) 1985-12-23 1991-02-26 Syngene, Inc. Fluorescent stokes shift probes for polynucleotide hybridization
ATE112314T1 (de) 1988-05-17 1994-10-15 Lubrizol Genetics Inc Pflanzliches ubiquitinpromotorsystem.
ATE114507T1 (de) 1988-12-28 1994-12-15 Stefan Miltenyi Verfahren sowie materialien zur hochgraduierten magnetischen abspaltung biologischer materialien.
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5200084A (en) 1990-09-26 1993-04-06 Immunicon Corporation Apparatus and methods for magnetic separation
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
EP1067134B1 (en) 1991-11-07 2004-07-28 Nanotronics, Inc. Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system
WO1994019491A1 (en) 1993-02-17 1994-09-01 Genetic Therapy, Inc. Detection of replication competent viruses
US5834256A (en) 1993-06-11 1998-11-10 Cell Genesys, Inc. Method for production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells
US5925517A (en) 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
US5538848A (en) 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
US6451995B1 (en) 1996-03-20 2002-09-17 Sloan-Kettering Institute For Cancer Research Single chain FV polynucleotide or peptide constructs of anti-ganglioside GD2 antibodies, cells expressing same and related methods
US5928906A (en) 1996-05-09 1999-07-27 Sequenom, Inc. Process for direct sequencing during template amplification
SE506700C2 (sv) 1996-05-31 1998-02-02 Mikael Kubista Sond och förfaranden för analys av nukleinsyra
EP1442794B1 (en) 1996-06-04 2006-03-29 University Of Utah Research Foundation System and method for carrying out and monitoring biological processes
DE69739357D1 (de) 1996-06-04 2009-05-28 Univ Utah Res Found Überwachung der hybridisierung während pcr
EP0961830A1 (en) 1997-01-29 1999-12-08 Neurosearch A/S EXPRESSION VECTORS AND METHODS FOR $i(IN VIVO) EXPRESSION OF THERAPEUTIC POLYPEPTIDES
US6207455B1 (en) 1997-05-01 2001-03-27 Lung-Ji Chang Lentiviral vectors
US5994136A (en) 1997-12-12 1999-11-30 Cell Genesys, Inc. Method and means for producing high titer, safe, recombinant lentivirus vectors
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
WO2000014257A1 (en) 1998-09-04 2000-03-16 Sloan-Kettering Institute For Cancer Research Fusion receptors specific for prostate-specific membrane antigen and uses thereof
AU2472400A (en) 1998-10-20 2000-05-08 City Of Hope CD20-specific redirected T cells and their use in cellular immunotherapy of CD20+ malignancies
US6303293B1 (en) * 1999-02-02 2001-10-16 Ortho-Clinical Diagnostics, Inc. Oligonucleotide reverse transcription primers for efficient detection of HIV-1 and HIV-2 and methods of use thereof
WO2001004360A2 (en) 1999-07-09 2001-01-18 Uab Research Foundation Retroviral recombination assays and uses thereof
CA2410510A1 (en) 2000-06-02 2001-12-13 Memorial Sloan-Kettering Cancer Center Artificial antigen presenting cells and methods of use thereof
JP5213297B2 (ja) 2000-08-11 2013-06-19 ユニバーシティ オブ ユタ リサーチ ファウンデーション 単一ラベルオリゴヌクレオチド・プローブ
US7446179B2 (en) 2000-11-07 2008-11-04 City Of Hope CD19-specific chimeric T cell receptor
US6712612B1 (en) * 2000-12-12 2004-03-30 Genecure Llc Safe and stable retroviral helper cell line and related compositions and methods
US7070995B2 (en) 2001-04-11 2006-07-04 City Of Hope CE7-specific redirected immune cells
US20090257994A1 (en) 2001-04-30 2009-10-15 City Of Hope Chimeric immunoreceptor useful in treating human cancers
KR100440852B1 (ko) * 2001-05-10 2004-07-19 주식회사 바이로메드 레트로바이러스에 특이적인 올리고뉴클레오티드 프라이머및 이를 이용한 레트로바이러스 농도 측정방법
ITCZ20020002A1 (it) 2002-04-11 2003-10-13 Parco Scient E Tecnologico Del Dispositivo e metodo per il rilevamento simultaneo di differenti anticorpi e antigeni in campioni clinici, alimentari ed ambientali
US7446190B2 (en) 2002-05-28 2008-11-04 Sloan-Kettering Institute For Cancer Research Nucleic acids encoding chimeric T cell receptors
AU2003260769A1 (en) * 2002-09-03 2004-03-29 Oxford Biomedica (Uk) Limited Retroviral vector and stable packaging cell lines
US20050129671A1 (en) 2003-03-11 2005-06-16 City Of Hope Mammalian antigen-presenting T cells and bi-specific T cells
US7435596B2 (en) 2004-11-04 2008-10-14 St. Jude Children's Research Hospital, Inc. Modified cell line and method for expansion of NK cell
US20090028836A1 (en) 2005-06-01 2009-01-29 Kalle Christof Von Stem and progenitor cell expansion by evi, evi-like genes and setbp1
WO2007008309A2 (en) * 2005-06-01 2007-01-18 Children's Hospital Medical Center Stem and progenitor cell expansion by evi, evi-like genes and setbp1
CA2624917C (en) 2005-10-05 2013-07-09 F. Hoffmann-La Roche Ag Non-fluorescent energy transfer
US8389282B2 (en) 2007-03-30 2013-03-05 Memorial Sloan-Kettering Cancer Center Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes
EP2520643B8 (en) 2007-12-07 2019-11-27 Miltenyi Biotec B.V. & Co. KG Sample processing systems and methods
US8479118B2 (en) 2007-12-10 2013-07-02 Microsoft Corporation Switching search providers within a browser search box
LT2222861T (lt) 2007-12-11 2018-03-26 The University Of North Carolina At Chapel Hill Retrovirusiniai vektoriai modifikuoti polipurino atkarpa
US20120164718A1 (en) 2008-05-06 2012-06-28 Innovative Micro Technology Removable/disposable apparatus for MEMS particle sorting device
JP5173594B2 (ja) 2008-05-27 2013-04-03 キヤノン株式会社 管理装置、画像形成装置及びそれらの処理方法
WO2010075414A2 (en) * 2008-12-23 2010-07-01 The Cleveland Clinic Foundation Method for detection of xmrv
CN102154368B (zh) 2010-02-11 2015-01-21 上海比昂生物医药科技有限公司 一种组织特异性兼可调控性慢病毒基因表达载体
PH12013501201A1 (en) 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
WO2012129514A1 (en) 2011-03-23 2012-09-27 Fred Hutchinson Cancer Research Center Method and compositions for cellular immunotherapy
US8398282B2 (en) 2011-05-12 2013-03-19 Delphi Technologies, Inc. Vehicle front lighting assembly and systems having a variable tint electrowetting element
WO2013071154A1 (en) 2011-11-11 2013-05-16 Fred Hutchinson Cancer Research Center Cyclin a1-targeted t-cell immunotherapy for cancer
EP2814846B1 (en) 2012-02-13 2020-01-08 Seattle Children's Hospital d/b/a Seattle Children's Research Institute Bispecific chimeric antigen receptors and therapeutic uses thereof
WO2013126726A1 (en) 2012-02-22 2013-08-29 The Trustees Of The University Of Pennsylvania Double transgenic t cells comprising a car and a tcr and their methods of use
NZ702108A (en) 2012-05-03 2016-09-30 Hutchinson Fred Cancer Res Enhanced affinity t cell receptors and methods for making the same
KR20210149195A (ko) 2012-07-13 2021-12-08 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 형질도입된 t 세포의 투여 적합성을 평가하는 방법
LT2884999T (lt) 2012-08-20 2021-04-12 Fred Hutchinson Cancer Research Center Ląstelinės imunoterapijos būdas ir kompozicijos
RU2729401C2 (ru) 2012-10-02 2020-08-06 Мемориал Слоан-Кеттеринг Кэнсер Сентер Композиции и способы для иммунотерапии
CN105555972B (zh) 2013-07-25 2020-07-31 伯乐生命医学产品有限公司 遗传测定
JP6412579B2 (ja) 2014-01-10 2018-10-24 シリオン・バイオテック・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 偽型レンチウイルスベクター
KR20240164967A (ko) * 2014-02-04 2024-11-21 카이트 파마 인코포레이티드 B 세포 악성종양 및 다른 암을 치료하는데 유용한 자가 t 세포 및 그의 조성물의 생산 방법
CN111918972A (zh) 2018-01-31 2020-11-10 朱诺治疗学股份有限公司 评估存在或不存在有复制能力的病毒的方法和试剂

Similar Documents

Publication Publication Date Title
CN107502608B (zh) 用于敲除人ALDH2基因的sgRNA、ALDH2基因缺失细胞株的构建方法及应用
Hayman et al. A universal real-time assay for the detection of Lyssaviruses
JP2021511802A5 (enExample)
Robles-Sikisaka et al. Evidence of recombination and positive selection in cetacean papillomaviruses
Sasai et al. A novel non-segmented double-stranded RNA virus from an Arctic isolate of Pythium polare
WO2016187904A1 (zh) CRISPR-Cas9特异性敲除猪CMAH基因的方法及用于特异性靶向CMAH基因的sgRNA
Arai et al. Molecular phylogeny of a genetically divergent hantavirus harbored by the Geoffroy's rousette (Rousettus amplexicaudatus), a frugivorous bat species in the Philippines
WO2016197361A1 (zh) CRISPR-Cas9特异性敲除猪GGTA1基因的方法及用于特异性靶向GGTA1基因的sgRNA
CN110066771B (zh) 一种hiv-1重组型、检测整合酶区耐药突变的引物组、方法及其应用
Yashina et al. Hokkaido genotype of Puumala virus in the grey red-backed vole (Myodes rufocanus) and northern red-backed vole (Myodes rutilus) in Siberia
Alkie et al. Molecular characterization of hemorrhagic enteritis viruses (HEV) detected in HEV-vaccinated commercial turkey flocks in Germany
KR20180115967A (ko) FCoV, CCoV 및 TGEV를 동시에 검출하기 위한 프라이머 및 이를 이용한 검출 방법
Chao et al. Analyses of a whole-genome inter-clade recombination map of hepatitis delta virus suggest a host polymerase-driven and viral RNA structure-promoted template-switching mechanism for viral RNA recombination
Jin et al. Genetic characterization of porcine kobuvirus variants identified from healthy piglets in China
Mirhosseini et al. Complete sequence of human T cell leukemia virus type 1 in ATLL patients from Northeast Iran, Mashhad revealed a prematurely terminated protease and an elongated pX open reading frame III
El Beaino et al. Molecular detection of Grapevine fleck virus-like viruses
Kremer et al. Genotyping of recent measles virus strains from Russia and Vietnam by nucleotide‐specific multiplex PCR
Butina et al. Canine distemper virus diversity in Lake Baikal seal (Phoca sibirica) population
Short et al. Novel phycodnavirus genes amplified from Canadian freshwater environments
Longet et al. Higher-level phylogeny of Foraminifera inferred from the RNA polymerase II (RPB1) gene
CN101402945A (zh) 表达抗传染性法氏囊病病毒微小rna重组禽腺联病毒的制备方法
Deng et al. Development of a loop-mediated isothermal amplification method for rapid detection of reticuloendotheliosis virus
KR102155967B1 (ko) 미토콘드리아 삽입 마커에서 유래한 가시배새우 종 판별용 유전자 마커 조성물 및 이를 이용한 가시배새우 판별방법
Almeyda et al. Comparative analysis of endogenous plant pararetroviruses in cultivated and wild Dahlia spp.
JP2015027283A (ja) カニクイザルmhc遺伝子のマルチプレックスdnaタイピング方法及びプライマーセット