JP2019520422A5 - - Google Patents
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- JP2019520422A5 JP2019520422A5 JP2019514195A JP2019514195A JP2019520422A5 JP 2019520422 A5 JP2019520422 A5 JP 2019520422A5 JP 2019514195 A JP2019514195 A JP 2019514195A JP 2019514195 A JP2019514195 A JP 2019514195A JP 2019520422 A5 JP2019520422 A5 JP 2019520422A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- dynein
- nucleic acid
- acid construct
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022098210A JP2022120180A (ja) | 2016-05-27 | 2022-06-17 | 合成メッセンジャーｒｎａによる原発性繊毛機能不全症の治療 |
| JP2025030716A JP2025090635A (ja) | 2016-05-27 | 2025-02-27 | 合成メッセンジャーｒｎａによる原発性繊毛機能不全症の治療 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662342784P | 2016-05-27 | 2016-05-27 | |
| US62/342,784 | 2016-05-27 | ||
| PCT/US2017/034723 WO2017205767A1 (en) | 2016-05-27 | 2017-05-26 | Treatment of primary ciliary dyskinesia with synthetic messenger rna |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022098210A Division JP2022120180A (ja) | 2016-05-27 | 2022-06-17 | 合成メッセンジャーｒｎａによる原発性繊毛機能不全症の治療 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019520422A JP2019520422A (ja) | 2019-07-18 |
| JP2019520422A5 true JP2019520422A5 (https=) | 2020-07-02 |
| JP7672786B2 JP7672786B2 (ja) | 2025-05-08 |
Family
ID=60411943
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514195A Active JP7672786B2 (ja) | 2016-05-27 | 2017-05-26 | 合成メッセンジャーｒｎａによる原発性繊毛機能不全症の治療 |
| JP2022098210A Pending JP2022120180A (ja) | 2016-05-27 | 2022-06-17 | 合成メッセンジャーｒｎａによる原発性繊毛機能不全症の治療 |
| JP2025030716A Pending JP2025090635A (ja) | 2016-05-27 | 2025-02-27 | 合成メッセンジャーｒｎａによる原発性繊毛機能不全症の治療 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022098210A Pending JP2022120180A (ja) | 2016-05-27 | 2022-06-17 | 合成メッセンジャーｒｎａによる原発性繊毛機能不全症の治療 |
| JP2025030716A Pending JP2025090635A (ja) | 2016-05-27 | 2025-02-27 | 合成メッセンジャーｒｎａによる原発性繊毛機能不全症の治療 |
Country Status (10)
| Country | Link |
|---|---|
| US (6) | US20190117796A1 (https=) |
| EP (2) | EP3463483B1 (https=) |
| JP (3) | JP7672786B2 (https=) |
| CN (2) | CN117018228A (https=) |
| AU (3) | AU2017271665B2 (https=) |
| CA (1) | CA3025626A1 (https=) |
| DK (1) | DK3463483T3 (https=) |
| ES (1) | ES2972405T3 (https=) |
| PT (1) | PT3463483T (https=) |
| WO (1) | WO2017205767A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117018228A (zh) | 2016-05-27 | 2023-11-10 | 创思瑞普泰克斯公司 | 用合成信使rna治疗原发性纤毛运动障碍 |
| KR102832035B1 (ko) * | 2017-09-29 | 2025-07-09 | 인텔리아 테라퓨틱스, 인크. | 지질 나노파티클을 이용한 mRNA 전달의 체외 방법 |
| CA3100946A1 (en) | 2018-05-22 | 2019-11-28 | The Brigham And Women's Hospital, Inc. | Gene therapy for alzheimer's disease |
| KR102116449B1 (ko) * | 2018-10-01 | 2020-05-29 | 동국대학교 산학협력단 | Ofd1을 이용한 피부 탈색 질환 치료용 조성물의 스크리닝 방법 |
| JP2022516356A (ja) * | 2019-01-07 | 2022-02-25 | トランスレイト バイオ， インコーポレイテッド | 原発性線毛機能不全症の治療のための組成物および方法 |
| HUE065017T2 (hu) * | 2019-02-14 | 2024-04-28 | Ethris Gmbh | Poliribonukleotid ciliogenezisre gyakorolt hatásának elemzése |
| JP7686573B6 (ja) | 2019-05-24 | 2025-07-04 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | アルツハイマー病のための遺伝子治療 |
| CN110438220A (zh) * | 2019-08-16 | 2019-11-12 | 深圳市人民医院 | 纤毛不动综合症基因面板试剂盒及其应用 |
| BR112022010373A2 (pt) * | 2019-11-29 | 2022-08-16 | Paros Bio Inc | Terapia genética para doenças neurodegenerativas |
| CN111500697A (zh) * | 2020-03-20 | 2020-08-07 | 四川省人民医院 | 不动纤毛综合症筛查试剂盒 |
| EP4146680A1 (en) * | 2020-05-07 | 2023-03-15 | Translate Bio, Inc. | Composition and methods for treatment of primary ciliary dyskinesia |
| US20240123087A1 (en) * | 2021-03-19 | 2024-04-18 | Recode Therapeutics, Inc. | Polynucleotide compositions, related formulations, and methods of use thereof |
| JP2024511463A (ja) * | 2021-03-22 | 2024-03-13 | リコード セラピューティクス，インク． | 細胞への標的送達のための組成物および方法 |
| WO2022204215A1 (en) * | 2021-03-22 | 2022-09-29 | Recode Therapeutics, Inc. | Polynucleotide compositions, related formulations, and methods of use thereof |
| WO2022204053A1 (en) * | 2021-03-22 | 2022-09-29 | Recode Therapeutics, Inc. | Polynucleotide compositions, related formulations, and methods of use thereof |
| CA3213107A1 (en) | 2021-03-23 | 2022-09-29 | Mirko HENNIG | Polynucleotide compositions, related formulations, and methods of use thereof |
| JP2024527541A (ja) * | 2021-07-01 | 2024-07-25 | トランスレイト バイオ， インコーポレイテッド | Ｍｒｎａの送達のための組成物 |
| EP4379055A4 (en) * | 2021-07-27 | 2025-08-06 | Sk Bioscience Co Ltd | MRNA FOR PROTEIN EXPRESSION AND TEMPLATE FOR IT |
| WO2023086893A1 (en) * | 2021-11-10 | 2023-05-19 | Translate Bio, Inc. | Composition and methods for treatment of primary ciliary dyskinesia |
| CN115287326B (zh) * | 2022-08-05 | 2025-05-16 | 中国科学院深圳先进技术研究院 | 一种评估流感嗜血杆菌感染性的方法 |
| EP4630057A1 (en) | 2022-12-08 | 2025-10-15 | Recode Therapeutics, Inc. | Lipid nanoparticle compositions and uses thereof |
| US12364773B2 (en) | 2023-12-01 | 2025-07-22 | Recode Therapeutics, Inc. | Lipid nanoparticle compositions and uses thereof |
| CN119709879B (zh) * | 2024-12-27 | 2025-09-26 | 天津大学 | efcab2基因在构建脑积水动物模型中的应用及模型的构建方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006138380A2 (en) | 2005-06-15 | 2006-12-28 | Massachusetts Institute Of Technology | Amine-containing lipids and uses thereof |
| CN101104853A (zh) * | 2007-06-21 | 2008-01-16 | 上海交通大学 | 小鼠Dnaic2基因序列 |
| WO2009154790A2 (en) * | 2008-06-20 | 2009-12-23 | University Of Massachusetts | Novel metastasis suppresor genes and uses thereof |
| EP3269395A1 (en) | 2008-11-07 | 2018-01-17 | Massachusetts Institute Of Technology | Aminoalcohol lipidoids and uses thereof |
| FR2948687B1 (fr) * | 2009-07-29 | 2015-09-04 | Centre Nat Rech Scient | Utilisation de microarn pour le traitement de pathologies respiratoires chroniques |
| CA2817256A1 (en) * | 2010-11-12 | 2012-05-18 | The General Hospital Corporation | Polycomb-associated non-coding rnas |
| EP3495497B1 (en) * | 2011-04-28 | 2021-03-24 | Life Technologies Corporation | Methods and compositions for multiplex pcr |
| WO2013134558A1 (en) * | 2012-03-07 | 2013-09-12 | The Texas A & M University System | Cancer treatment targeting non-coding rna overexpression |
| WO2013151665A2 (en) * | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins associated with human disease |
| US20150126589A1 (en) * | 2012-06-08 | 2015-05-07 | Ethris Gmbh | Pulmonary Delivery of Messenger RNA |
| JP6243919B2 (ja) * | 2012-10-24 | 2017-12-06 | フラウンホーファ−ゲゼルシャフト ツァー フォルデルング デア アンゲバンデン フォルシュンク エー． ファオ．Ｆｒａｕｎｈｏｆｅｒ−Ｇｅｓｅｌｌｓｃｈａｆｔ Ｚｕｒ Ｆｏｒｄｅｒｕｎｇ Ｄｅｒ Ａｎｇｅｗａｎｄｔｅｎ Ｆｏｒｓｃｈｕｎｇ Ｅ． Ｖ． | 微小管修飾化合物 |
| PL2922554T3 (pl) * | 2012-11-26 | 2022-06-20 | Modernatx, Inc. | Na zmodyfikowany na końcach |
| US20160032316A1 (en) * | 2013-03-14 | 2016-02-04 | The Trustees Of The University Of Pennsylvania | Purification and Purity Assessment of RNA Molecules Synthesized with Modified Nucleosides |
| CN106282195A (zh) * | 2013-04-28 | 2017-01-04 | 中国人民解放军总医院 | 基因突变体及其应用 |
| US20180126003A1 (en) * | 2016-05-04 | 2018-05-10 | Curevac Ag | New targets for rna therapeutics |
| WO2017191274A2 (en) * | 2016-05-04 | 2017-11-09 | Curevac Ag | Rna encoding a therapeutic protein |
| CN117018228A (zh) | 2016-05-27 | 2023-11-10 | 创思瑞普泰克斯公司 | 用合成信使rna治疗原发性纤毛运动障碍 |
| WO2019161459A1 (en) | 2018-02-26 | 2019-08-29 | Children's Medical Research Institute | Methods for codon optimization |
| WO2020051223A1 (en) | 2018-09-04 | 2020-03-12 | The Board Of Regents Of The University Of Texas System | Compositions and methods for organ specific delivery of nucleic acids |
| EP3846857A4 (en) | 2018-09-04 | 2022-10-12 | The Board Of Regents Of The University Of Texas System | COMPOSITIONS AND METHODS FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACIDS |
| JP2022516356A (ja) | 2019-01-07 | 2022-02-25 | トランスレイト バイオ， インコーポレイテッド | 原発性線毛機能不全症の治療のための組成物および方法 |
| HUE065017T2 (hu) | 2019-02-14 | 2024-04-28 | Ethris Gmbh | Poliribonukleotid ciliogenezisre gyakorolt hatásának elemzése |
| US20240123087A1 (en) * | 2021-03-19 | 2024-04-18 | Recode Therapeutics, Inc. | Polynucleotide compositions, related formulations, and methods of use thereof |
| WO2022204215A1 (en) | 2021-03-22 | 2022-09-29 | Recode Therapeutics, Inc. | Polynucleotide compositions, related formulations, and methods of use thereof |
-
2017
- 2017-05-26 CN CN202310963917.0A patent/CN117018228A/zh active Pending
- 2017-05-26 CA CA3025626A patent/CA3025626A1/en active Pending
- 2017-05-26 AU AU2017271665A patent/AU2017271665B2/en active Active
- 2017-05-26 EP EP17803679.4A patent/EP3463483B1/en active Active
- 2017-05-26 PT PT178036794T patent/PT3463483T/pt unknown
- 2017-05-26 EP EP23202277.2A patent/EP4316588A3/en active Pending
- 2017-05-26 JP JP2019514195A patent/JP7672786B2/ja active Active
- 2017-05-26 WO PCT/US2017/034723 patent/WO2017205767A1/en not_active Ceased
- 2017-05-26 CN CN201780046586.7A patent/CN109562192B/zh active Active
- 2017-05-26 DK DK17803679.4T patent/DK3463483T3/da active
- 2017-05-26 ES ES17803679T patent/ES2972405T3/es active Active
-
2018
- 2018-11-15 US US16/192,622 patent/US20190117796A1/en not_active Abandoned
- 2018-11-15 US US16/192,661 patent/US20190111074A1/en not_active Abandoned
-
2020
- 2020-07-28 US US16/941,028 patent/US11642421B2/en active Active
-
2022
- 2022-02-09 US US17/668,346 patent/US11510997B2/en active Active
- 2022-06-17 JP JP2022098210A patent/JP2022120180A/ja active Pending
- 2022-10-20 US US18/048,253 patent/US11786610B2/en active Active
-
2023
- 2023-09-05 US US18/461,021 patent/US20240285798A1/en not_active Abandoned
-
2024
- 2024-02-12 AU AU2024200877A patent/AU2024200877B2/en active Active
-
2025
- 2025-02-27 JP JP2025030716A patent/JP2025090635A/ja active Pending
- 2025-04-07 AU AU2025202461A patent/AU2025202461A1/en active Pending
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