JP2019518426A - がんの診断及び治療方法 - Google Patents

がんの診断及び治療方法 Download PDF

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JP2019518426A
JP2019518426A JP2018554110A JP2018554110A JP2019518426A JP 2019518426 A JP2019518426 A JP 2019518426A JP 2018554110 A JP2018554110 A JP 2018554110A JP 2018554110 A JP2018554110 A JP 2018554110A JP 2019518426 A JP2019518426 A JP 2019518426A
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cancer
mapk
patient
dusp6
spry4
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JP2019518426A5 (https=
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ダニエル クリストファー ケルアック，
ダニエル クリストファー ケルアック，
マリー−クレール ワグル，
マリー−クレール ワグル，
シー−ミン ホアン，
シー−ミン ホアン，
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Genentech Inc
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Genentech Inc
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    • A—HUMAN NECESSITIES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57595—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving intracellular compounds
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Animal Behavior & Ethology (AREA)
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  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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JP2018554110A 2016-04-15 2017-04-11 がんの診断及び治療方法 Pending JP2019518426A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662323210P 2016-04-15 2016-04-15
US62/323,210 2016-04-15
PCT/US2017/026941 WO2017180581A1 (en) 2016-04-15 2017-04-11 Diagnostic and therapeutic methods for cancer

Publications (2)

Publication Number Publication Date
JP2019518426A true JP2019518426A (ja) 2019-07-04
JP2019518426A5 JP2019518426A5 (https=) 2020-05-28

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JP2018554110A Pending JP2019518426A (ja) 2016-04-15 2017-04-11 がんの診断及び治療方法

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US (1) US20190032150A1 (https=)
EP (1) EP3443114A1 (https=)
JP (1) JP2019518426A (https=)
KR (1) KR20180134347A (https=)
CN (1) CN109072311A (https=)
AU (1) AU2017249229A1 (https=)
CA (1) CA3018406A1 (https=)
IL (1) IL262208A (https=)
MX (1) MX2018012471A (https=)
WO (1) WO2017180581A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
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WO2022255401A1 (ja) * 2021-06-03 2022-12-08 国立大学法人 東京大学 Ｅｒｋ－ｍａｐｋ経路の異常な活性化に伴い発現する疾患マーカー
JP2023519807A (ja) * 2020-02-25 2023-05-15 ボルト バイオセラピューティクス、インコーポレーテッド 癌治療方法

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JP7379355B2 (ja) * 2017-11-20 2023-11-14 トルレモ セラピューティクス アーゲー 診断方法
WO2020046966A1 (en) * 2018-08-27 2020-03-05 Kura Oncology, Inc. Treatment of adenocarcinomas with mapk pathway inhibitors
CN109609640A (zh) * 2019-01-14 2019-04-12 中国科学院上海高等研究院 Etv4的用途
US20220160714A1 (en) * 2019-03-22 2022-05-26 Icahn School Of Medicine At Mount Sinai Methods for treating colorectal cancer
CN109925316B (zh) * 2019-03-26 2021-09-14 广州医科大学附属第二医院 一种治疗溃疡性结肠炎的药物
WO2021007499A1 (en) * 2019-07-11 2021-01-14 Emory University Combination therapies for managing cancer
TW202200147A (zh) * 2020-05-26 2022-01-01 韓商韓美藥品股份有限公司 Ｂｅｌｖａｒａｆｅｎｉｂ用於癌症治療
WO2022250431A1 (ko) 2021-05-25 2022-12-01 주식회사 박셀바이오 모노바디 기반 키메라 항원 수용체 및 이를 포함하는 면역 세포
CN113318105B (zh) * 2021-05-31 2023-02-03 新乡医学院 含Binimetinib的用于治疗结肠癌的药物组合物及其应用
CN114085909A (zh) * 2021-11-09 2022-02-25 重庆医科大学 Top1作为宫颈癌标志物和/或治疗靶点的应用
KR102849117B1 (ko) 2022-02-07 2025-08-21 한국화학연구원 흑색종 치료 내성 예측용 trim51 바이오마커 및 이의 용도
WO2023219443A1 (ko) * 2022-05-11 2023-11-16 동아대학교 산학협력단 방광암의 전이성 바이오마커
CN115993455A (zh) * 2022-12-29 2023-04-21 南京医科大学康达学院 Rna结合蛋白nova2作为非小细胞肺癌转移标志物的应用

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