JP2019518052A5 - - Google Patents
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- Publication number
- JP2019518052A5 JP2019518052A5 JP2018565750A JP2018565750A JP2019518052A5 JP 2019518052 A5 JP2019518052 A5 JP 2019518052A5 JP 2018565750 A JP2018565750 A JP 2018565750A JP 2018565750 A JP2018565750 A JP 2018565750A JP 2019518052 A5 JP2019518052 A5 JP 2019518052A5
- Authority
- JP
- Japan
- Prior art keywords
- diabetes
- tumor
- treatment
- pharmaceutically acceptable
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010012601 Diabetes mellitus Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 206010039073 Rheumatoid arthritis Diseases 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
Claims (1)
- 腫瘍、糖尿病、及び／又は関節リウマチの治療に用いるための、請求項1〜9のいずれかに記載の化合物またはその薬学的に許容される塩あるいは請求項10に記載の薬物組成物。
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610428049 | 2016-06-16 | ||
| CN201610428049.6 | 2016-06-16 | ||
| CN201610674021.0 | 2016-08-15 | ||
| CN201610674021 | 2016-08-15 | ||
| PCT/CN2017/088030 WO2017215588A1 (zh) | 2016-06-16 | 2017-06-13 | 作为Akt抑制剂的二氢吡唑氮杂卓类化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019518052A JP2019518052A (ja) | 2019-06-27 |
| JP2019518052A5 true JP2019518052A5 (ja) | 2020-05-14 |
| JP6900406B2 JP6900406B2 (ja) | 2021-07-07 |
Family
ID=60663995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018565750A Active JP6900406B2 (ja) | 2016-06-16 | 2017-06-13 | Ａｋｔ阻害剤としてのジヒドロピラゾロアゼピン系化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10654868B2 (ja) |
| EP (1) | EP3473628B1 (ja) |
| JP (1) | JP6900406B2 (ja) |
| KR (1) | KR102351270B1 (ja) |
| CN (1) | CN109311908B (ja) |
| WO (1) | WO2017215588A1 (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111433213B (zh) * | 2017-12-13 | 2023-03-10 | 哈尔滨珍宝制药有限公司 | 作为Akt抑制剂的盐型及其晶型 |
| CN116583525A (zh) * | 2020-12-07 | 2023-08-11 | 南京正大天晴制药有限公司 | 一种吡唑并氮杂卓类akt抑制剂 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6887864B2 (en) * | 2002-03-12 | 2005-05-03 | Hoffmann-La Roche Inc. | Azepane derivatives |
| CN101094833A (zh) * | 2004-07-12 | 2007-12-26 | 伊邓药品公司 | 四肽类似物 |
| US8207180B2 (en) * | 2006-11-28 | 2012-06-26 | Nerviano Medical Sciences S.R.L. | Tricyclic indoles and (4,5-dihydro) indoles |
| UY30892A1 (es) * | 2007-02-07 | 2008-09-02 | Smithkline Beckman Corp | Inhibidores de la actividad akt |
| DE602008003055D1 (de) | 2007-05-31 | 2010-12-02 | Nerviano Medical Sciences Srl | Zyklokondensierte Azaindole, die als Kinase-Hemmer wirken |
| JP2011509261A (ja) * | 2008-01-07 | 2011-03-24 | シンタ ファーマシューティカルズ コーポレーション | 炎症および免疫関連用途向けの化合物 |
| US20110129455A1 (en) | 2008-06-26 | 2011-06-02 | Hong Lin | Inhibitors of akt activity |
| RU2013126036A (ru) | 2010-11-17 | 2014-12-27 | Ф. Хоффманн-Ля Рош Аг | Способ лечения опухолей |
-
2017
- 2017-06-13 WO PCT/CN2017/088030 patent/WO2017215588A1/zh unknown
- 2017-06-13 KR KR1020197001396A patent/KR102351270B1/ko active IP Right Grant
- 2017-06-13 CN CN201780037686.3A patent/CN109311908B/zh active Active
- 2017-06-13 US US16/309,648 patent/US10654868B2/en active Active
- 2017-06-13 EP EP17812699.1A patent/EP3473628B1/en active Active
- 2017-06-13 JP JP2018565750A patent/JP6900406B2/ja active Active
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