JP2019517803A5 - - Google Patents
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- JP2019517803A5 JP2019517803A5 JP2018565376A JP2018565376A JP2019517803A5 JP 2019517803 A5 JP2019517803 A5 JP 2019517803A5 JP 2018565376 A JP2018565376 A JP 2018565376A JP 2018565376 A JP2018565376 A JP 2018565376A JP 2019517803 A5 JP2019517803 A5 JP 2019517803A5
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- Japan
- Prior art keywords
- genetically modified
- nucleic acid
- item
- exogenous nucleic
- modified non
- Prior art date
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Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021212142A JP2022031487A (ja) | 2016-06-14 | 2021-12-27 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
| JP2022129299A JP2022160703A (ja) | 2016-06-14 | 2022-08-15 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
| JP2024154774A JP2024178220A (ja) | 2016-06-14 | 2024-09-09 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
| JP2025015908A JP2025076449A (ja) | 2016-06-14 | 2025-02-03 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662350048P | 2016-06-14 | 2016-06-14 | |
| US62/350,048 | 2016-06-14 | ||
| PCT/US2017/037566 WO2017218714A1 (en) | 2016-06-14 | 2017-06-14 | Genetically modified cells, tissues, and organs for treating disease |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021212142A Division JP2022031487A (ja) | 2016-06-14 | 2021-12-27 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
| JP2022129299A Division JP2022160703A (ja) | 2016-06-14 | 2022-08-15 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019517803A JP2019517803A (ja) | 2019-06-27 |
| JP2019517803A5 true JP2019517803A5 (https=) | 2020-07-27 |
| JP7519660B2 JP7519660B2 (ja) | 2024-07-22 |
Family
ID=60663278
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018565376A Active JP7519660B2 (ja) | 2016-06-14 | 2017-06-14 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
| JP2021212142A Pending JP2022031487A (ja) | 2016-06-14 | 2021-12-27 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
| JP2022129299A Pending JP2022160703A (ja) | 2016-06-14 | 2022-08-15 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
| JP2024154774A Pending JP2024178220A (ja) | 2016-06-14 | 2024-09-09 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
| JP2025015908A Pending JP2025076449A (ja) | 2016-06-14 | 2025-02-03 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021212142A Pending JP2022031487A (ja) | 2016-06-14 | 2021-12-27 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
| JP2022129299A Pending JP2022160703A (ja) | 2016-06-14 | 2022-08-15 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
| JP2024154774A Pending JP2024178220A (ja) | 2016-06-14 | 2024-09-09 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
| JP2025015908A Pending JP2025076449A (ja) | 2016-06-14 | 2025-02-03 | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20190335726A1 (https=) |
| EP (1) | EP3468356A4 (https=) |
| JP (5) | JP7519660B2 (https=) |
| KR (2) | KR20230110373A (https=) |
| CN (2) | CN109640645B (https=) |
| AU (1) | AU2017285224B2 (https=) |
| CA (1) | CA3027428A1 (https=) |
| WO (1) | WO2017218714A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9458450B2 (en) | 2012-03-15 | 2016-10-04 | Flodesign Sonics, Inc. | Acoustophoretic separation technology using multi-dimensional standing waves |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US9950282B2 (en) | 2012-03-15 | 2018-04-24 | Flodesign Sonics, Inc. | Electronic configuration and control for acoustic standing wave generation |
| US10967298B2 (en) | 2012-03-15 | 2021-04-06 | Flodesign Sonics, Inc. | Driver and control for variable impedence load |
| SG11201602232UA (en) | 2013-09-24 | 2016-04-28 | Giner Inc | System for gas treatment of a cell implant |
| WO2015105955A1 (en) | 2014-01-08 | 2015-07-16 | Flodesign Sonics, Inc. | Acoustophoresis device with dual acoustophoretic chamber |
| CN116059378A (zh) | 2014-12-10 | 2023-05-05 | 明尼苏达大学董事会 | 用于治疗疾病的遗传修饰的细胞、组织和器官 |
| US11021699B2 (en) | 2015-04-29 | 2021-06-01 | FioDesign Sonics, Inc. | Separation using angled acoustic waves |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11459540B2 (en) | 2015-07-28 | 2022-10-04 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11474085B2 (en) | 2015-07-28 | 2022-10-18 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| US11085035B2 (en) | 2016-05-03 | 2021-08-10 | Flodesign Sonics, Inc. | Therapeutic cell washing, concentration, and separation utilizing acoustophoresis |
| WO2018075830A1 (en) | 2016-10-19 | 2018-04-26 | Flodesign Sonics, Inc. | Affinity cell extraction by acoustics |
| AU2017361260B2 (en) | 2016-11-15 | 2023-06-08 | Giner, Inc. | Percutaneous gas diffusion device suitable for use with a subcutaneous implant |
| CN110831656A (zh) | 2017-05-04 | 2020-02-21 | 吉纳生命科学公司 | 稳健的可植入气体递送装置和方法、系统以及包括该装置的装置 |
| KR102439221B1 (ko) | 2017-12-14 | 2022-09-01 | 프로디자인 소닉스, 인크. | 음향 트랜스듀서 구동기 및 제어기 |
| EP3866815B1 (en) * | 2018-10-19 | 2024-05-01 | Regents Of The University Of Minnesota | Transplant tolerance induction with carbodiimide treated tolerizing vaccine |
| EP3760718A1 (en) * | 2019-07-04 | 2021-01-06 | Medizinische Hochschule Hannover | Tissue for use as allogeneic or xenogeneic transplant and method for its production |
| CN111264469B (zh) * | 2020-02-27 | 2022-03-25 | 西安交通大学医学院第一附属医院 | 一种基因免疫诱导的甲状腺相关性眼病动物模型的构建方法及雷帕霉素类药物的应用 |
| US20230123863A1 (en) * | 2020-06-30 | 2023-04-20 | National Yang-Ming University | A glia cell and neuron co-culture system and method |
| CN111500693B (zh) * | 2020-07-02 | 2020-09-22 | 中南大学 | 检测巨噬细胞中rfx1表达水平的试剂在制备巨噬细胞分型检测制剂中的应用 |
| WO2023015307A1 (en) * | 2021-08-06 | 2023-02-09 | Rutgers, The State University Of New Jersey | Method for producing genetically modified cells |
| US20240358761A1 (en) * | 2021-08-11 | 2024-10-31 | Sana Biotechnology, Inc. | Genetically modified cells for allogeneic cell therapy |
| CN114958768B (zh) * | 2022-06-02 | 2023-03-24 | 健颐生物科技发展(山东)有限公司 | Fgf10旁分泌通用型人成纤维细胞制剂的制备方法 |
| WO2026039661A1 (en) * | 2024-08-15 | 2026-02-19 | Regeneron Pharmaceuticals, Inc. | Non-human animals with humanized fc epsilon receptors that lack functional alpha-1, 3-galactosyltransferase (ggta1) |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6156306A (en) * | 1994-08-17 | 2000-12-05 | Albert Einstein College Of Medicine Of Yeshiva University | Pancreatic β-cells for allogeneic transplantation without immunosuppression |
| US5770201A (en) * | 1994-12-23 | 1998-06-23 | Rijsuniversiteit Te Leiden | HA-2 antigenic peptide |
| JPH11510698A (ja) * | 1995-08-04 | 1999-09-21 | ザ ジェネラル ホスピタル コーポレイション | トランスジェニックブタ及びヒトhla遺伝子を有するブタ細胞 |
| EP0892643B2 (en) * | 1996-03-20 | 2009-09-02 | Bristol-Myers Squibb Company | Methods for inhibiting an immune response by blocking the gp39/cd40 and ctla4/cd28/b7 pathways and compositions for use therewith |
| FR2760023B1 (fr) * | 1997-02-21 | 2004-05-07 | Commissariat Energie Atomique | Cellules eucaryotes exprimant a leur surface au moins une isoforme d'hla-g et leurs applications |
| WO2002064748A2 (en) * | 2001-02-14 | 2002-08-22 | Furcht Leo T | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof |
| CN1377225A (zh) * | 1999-09-13 | 2002-10-30 | 马萨诸塞大学 | 使用来自分化细胞的供体细胞或细胞核克隆猪以及多能猪的生成 |
| KR100417566B1 (ko) * | 1999-11-19 | 2004-02-05 | 한국생명공학연구원 | 체세포 핵치환 복제수정란의 대량생산방법 |
| AU2001297523B2 (en) * | 2000-11-17 | 2007-01-18 | Sab, Llc | Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulates |
| AU2002357110A1 (en) * | 2001-12-07 | 2003-07-09 | The Ohio State University Research Foundation | Apoptotic ebv-transformed lymphocytes, a therapeutic agent for post-transplant lymphoproliferative disorder |
| US20050123525A1 (en) * | 2003-11-13 | 2005-06-09 | Ulrich Martin | Composition and method for inducing immune tolerance towards cell, tissue and/or organ transplants |
| KR20090068646A (ko) * | 2007-12-24 | 2009-06-29 | (주)엠젠 | Hla-g 유전자 및 daf 유전자를 발현하는 형질전환복제 돼지 및 그의 제조 방법 |
| KR20100022684A (ko) * | 2008-08-20 | 2010-03-03 | (주)엠젠 | 세 개의 유전자를 발현하는 복합형질전환 복제 돼지 및 그의 제조 방법 |
| WO2010037408A1 (en) * | 2008-09-30 | 2010-04-08 | Curevac Gmbh | Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof |
| EP2184070A1 (en) * | 2008-11-07 | 2010-05-12 | Hla-G Technologies | HLA-G proteins and pharmaceutical uses thereof |
| EP2184297A1 (en) * | 2008-11-07 | 2010-05-12 | Hla-G Technologies | HLA-G polypeptides and pharmaceutical uses thereof |
| CN102300578A (zh) * | 2008-12-01 | 2011-12-28 | 延寿有限责任公司 | 用于改变健康、安康和寿命的方法和组合物 |
| JP5940977B2 (ja) * | 2009-08-11 | 2016-06-29 | サンガモ バイオサイエンシーズ, インコーポレイテッド | 標的改変によるホモ接合生物 |
| ES2767881T3 (es) * | 2009-08-14 | 2020-06-18 | Revivicor Inc | Cerdos multi-transgénicos para el tratamiento de diabetes |
| US8734786B2 (en) * | 2009-09-16 | 2014-05-27 | Northwestern University | Use of ECDI-fixed cell tolerance as a method for preventing allograft rejection |
| US20130177577A1 (en) * | 2010-07-12 | 2013-07-11 | Dana-Farber Cancer Institute, Inc. | Nlrc5 as a target to intervene mhc class 1-mediated immune responses |
| WO2012031008A2 (en) * | 2010-08-31 | 2012-03-08 | The General Hospital Corporation | Cancer-related biological materials in microvesicles |
| WO2012072096A1 (en) * | 2010-12-03 | 2012-06-07 | Biontech Ag | Method for cellular rna expression |
| ES2680636T3 (es) * | 2011-02-14 | 2018-09-10 | Revivicor Inc. | Cerdos genéticamente modificados para xenotrasplante de xenoinjertos vascularizados y derivados de los mismos |
| MX363013B (es) * | 2011-02-25 | 2019-03-04 | Recombinetics Inc | Animales genéticamente modificados y métodos para su obtención. |
| CN102911270A (zh) * | 2011-08-05 | 2013-02-06 | 浙江大学 | 一种抑制移植器官慢性排斥反应的抗体的制备及纯化方法 |
| DK2830662T3 (da) * | 2012-03-29 | 2019-01-02 | Univ Columbia | Fremgangsmåder til behandlng af hårtabsforstyrrelser |
| WO2013188358A1 (en) * | 2012-06-12 | 2013-12-19 | The General Hospital Corporation | Miniature swine transgenic for one or more coagulation factors |
| SG11201500799YA (en) * | 2012-07-31 | 2015-03-30 | Basil M Hantash | Hla g-modified cells and methods |
| US20140115728A1 (en) * | 2012-10-24 | 2014-04-24 | A. Joseph Tector | Double knockout (gt/cmah-ko) pigs, organs and tissues |
| CN104046593A (zh) * | 2013-03-14 | 2014-09-17 | 浙江大学 | 一种低免疫原性的人细胞及其制备方法 |
| UY35468A (es) * | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| JP2016538001A (ja) * | 2013-11-28 | 2016-12-08 | ホライズン・ジェノミクス・ゲーエムベーハー | 体細胞半数体ヒト細胞株 |
| WO2015184259A1 (en) * | 2014-05-30 | 2015-12-03 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods to treat latent viral infections |
| SI3161128T1 (sl) * | 2014-06-26 | 2019-02-28 | Regeneron Pharmaceuticals, Inc. | Postopki in sestavki za ciljano genetsko spremembo in postopki uporabe |
| CN105586389A (zh) * | 2014-10-21 | 2016-05-18 | 天津华大基因科技有限公司 | 试剂盒及其在检测遗传性骨病基因中的用途 |
| CA2965550A1 (en) * | 2014-10-22 | 2016-04-28 | Indiana University Research & Technology Corporation | Triple transgenic pigs suitable for xenograft |
| CN116059378A (zh) * | 2014-12-10 | 2023-05-05 | 明尼苏达大学董事会 | 用于治疗疾病的遗传修饰的细胞、组织和器官 |
| CN104789592A (zh) * | 2015-03-19 | 2015-07-22 | 中国食品药品检定研究院 | 一种制备α-1,3GT基因敲除的非人哺乳动物的方法及应用 |
-
2017
- 2017-06-14 KR KR1020237022996A patent/KR20230110373A/ko not_active Ceased
- 2017-06-14 JP JP2018565376A patent/JP7519660B2/ja active Active
- 2017-06-14 WO PCT/US2017/037566 patent/WO2017218714A1/en not_active Ceased
- 2017-06-14 CN CN201780049966.6A patent/CN109640645B/zh active Active
- 2017-06-14 KR KR1020197001275A patent/KR20190017985A/ko not_active Ceased
- 2017-06-14 US US16/312,052 patent/US20190335726A1/en not_active Abandoned
- 2017-06-14 AU AU2017285224A patent/AU2017285224B2/en active Active
- 2017-06-14 CN CN202111165647.6A patent/CN114176043B/zh active Active
- 2017-06-14 CA CA3027428A patent/CA3027428A1/en active Pending
- 2017-06-14 EP EP17814052.1A patent/EP3468356A4/en active Pending
-
2021
- 2021-12-27 JP JP2021212142A patent/JP2022031487A/ja active Pending
-
2022
- 2022-08-15 JP JP2022129299A patent/JP2022160703A/ja active Pending
-
2024
- 2024-09-09 JP JP2024154774A patent/JP2024178220A/ja active Pending
-
2025
- 2025-02-03 JP JP2025015908A patent/JP2025076449A/ja active Pending
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