JP2019515043A5 - - Google Patents
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- JP2019515043A5 JP2019515043A5 JP2019510575A JP2019510575A JP2019515043A5 JP 2019515043 A5 JP2019515043 A5 JP 2019515043A5 JP 2019510575 A JP2019510575 A JP 2019510575A JP 2019510575 A JP2019510575 A JP 2019510575A JP 2019515043 A5 JP2019515043 A5 JP 2019515043A5
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021204755A JP7389786B2 (ja) | 2016-05-05 | 2021-12-17 | 統合的ストレス経路のモジュレーター |
| JP2023195552A JP7755632B2 (ja) | 2016-05-05 | 2023-11-17 | 統合的ストレス経路のモジュレーター |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662332278P | 2016-05-05 | 2016-05-05 | |
| US62/332,278 | 2016-05-05 | ||
| PCT/US2017/031360 WO2017193034A1 (en) | 2016-05-05 | 2017-05-05 | Modulators of the integrated stress pathway |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021204755A Division JP7389786B2 (ja) | 2016-05-05 | 2021-12-17 | 統合的ストレス経路のモジュレーター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019515043A JP2019515043A (ja) | 2019-06-06 |
| JP2019515043A5 true JP2019515043A5 (OSRAM) | 2020-06-25 |
| JP6997766B2 JP6997766B2 (ja) | 2022-01-20 |
Family
ID=58709639
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019510575A Active JP6997766B2 (ja) | 2016-05-05 | 2017-05-05 | 統合的ストレス経路のモジュレーター |
| JP2021204755A Active JP7389786B2 (ja) | 2016-05-05 | 2021-12-17 | 統合的ストレス経路のモジュレーター |
| JP2023195552A Active JP7755632B2 (ja) | 2016-05-05 | 2023-11-17 | 統合的ストレス経路のモジュレーター |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021204755A Active JP7389786B2 (ja) | 2016-05-05 | 2021-12-17 | 統合的ストレス経路のモジュレーター |
| JP2023195552A Active JP7755632B2 (ja) | 2016-05-05 | 2023-11-17 | 統合的ストレス経路のモジュレーター |
Country Status (38)
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3066328A1 (en) * | 2017-06-07 | 2018-12-13 | Glaxosmithkline Intellectual Property Development Limited | Chemical compounds as atf4 pathway inhibitors |
| JP2020525513A (ja) * | 2017-07-03 | 2020-08-27 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ | 癌および他の疾患を治療するためのａｔｆ４阻害剤としてのｎ−（３−（２−（４−クロロフェノキシ）アセトアミドビシクロ［１．１．１］ペンタン−１−イル）−２−シクロブタン−１−カルボキサミド誘導体および関連化合物 |
| MA49858A (fr) * | 2017-08-09 | 2021-04-28 | Denali Therapeutics Inc | Composés, compositions et procédés |
| JP7382308B2 (ja) | 2017-09-01 | 2023-11-16 | デナリ セラピューティクス インコーポレイテッド | 化合物、組成物、及び、方法 |
| UY37958A (es) * | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| UY37956A (es) * | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| WO2019090088A1 (en) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| EP3723762A4 (en) | 2017-12-13 | 2021-12-08 | Praxis Biotech LLC | STRESS INTEGRATED RESPONSE PATH INHIBITORS |
| WO2019183589A1 (en) * | 2018-03-23 | 2019-09-26 | Denali Therapeutics Inc. | Modulators of eukaryotic initiation factor 2 |
| WO2019236710A1 (en) | 2018-06-05 | 2019-12-12 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| BR112021000332A2 (pt) * | 2018-07-09 | 2021-04-06 | Glaxosmithkline Intellectual Property Development Limited | Compostos químicos |
| TWI771621B (zh) * | 2018-10-11 | 2022-07-21 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| CA3129609A1 (en) | 2019-02-13 | 2020-08-20 | Denali Therapeutics Inc. | Eukaryotic initiation factor 2b modulators |
| EP3924341A4 (en) | 2019-02-13 | 2022-11-02 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| CN113840597A (zh) * | 2019-02-25 | 2021-12-24 | 普拉西斯生物技术有限责任公司 | 整合应激反应通路抑制剂 |
| KR20220004105A (ko) | 2019-04-23 | 2022-01-11 | 에보텍 인터내셔널 게엠베하 | 통합 스트레스 반응 경로의 조절제 |
| EA202192900A1 (ru) | 2019-04-23 | 2022-03-18 | Эвотек Интернешнл Гмбх | Модуляторы пути интегрированной реакции на стресс |
| SG11202111970WA (en) * | 2019-04-30 | 2021-11-29 | Calico Life Sciences Llc | Substituted cyclolakyls as modulators of the integrated stress pathway |
| AU2020264485A1 (en) * | 2019-04-30 | 2021-12-02 | Abbvie Inc. | Substituted cycloalkyls as modulators of the integrated stress pathway |
| CN114466654A (zh) | 2019-06-12 | 2022-05-10 | 普拉西斯生物技术有限责任公司 | 整合应激反应通路调节剂 |
| LT4069691T (lt) * | 2019-12-06 | 2024-12-10 | Vertex Pharmaceuticals Incorporated | Pakeistieji tetrahidrofuranai kaip natrio kanalų moduliatoriai |
| KR20220133252A (ko) | 2020-01-28 | 2022-10-04 | 에보텍 인터내셔널 게엠베하 | 통합 스트레스 반응 경로의 조절자 |
| US12441720B2 (en) | 2020-03-11 | 2025-10-14 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| US11351149B2 (en) | 2020-09-03 | 2022-06-07 | Pfizer Inc. | Nitrile-containing antiviral compounds |
| LT4232154T (lt) | 2020-10-22 | 2025-02-10 | Evotec International Gmbh | Integruoto streso atsako kelio moduliatoriai |
| MX2023004677A (es) | 2020-10-22 | 2023-05-24 | Evotec Int Gmbh | Moduladores de la via de respuesta integrada al estres. |
| KR20230110511A (ko) | 2020-10-22 | 2023-07-24 | 에보텍 인터내셔널 게엠베하 | 통합 스트레스 반응 경로의 조절제 |
| AU2021397774A1 (en) * | 2020-12-10 | 2023-06-29 | Adgero Biopharmaceuticals Holdings, Inc. | Methods for treating cutaneous metastatic cancers |
| KR20250122004A (ko) * | 2024-02-05 | 2025-08-13 | 재단법인 대구경북첨단의료산업진흥재단 | 신규한 eIF2B 작용제 및 이를 포함하는 대사질환 예방 또는 치료용 조성물 |
Family Cites Families (18)
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|---|---|---|---|---|
| US162A (en) | 1837-04-17 | Island | ||
| US5212A (en) | 1847-07-31 | Richard m | ||
| US4911920A (en) | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| JP2594486B2 (ja) | 1991-01-15 | 1997-03-26 | アルコン ラボラトリーズ インコーポレイテッド | 局所的眼薬組成物 |
| GB0400196D0 (en) * | 2004-01-07 | 2004-02-11 | Astrazeneca Ab | Therapeutic agents |
| US20070185079A1 (en) * | 2004-01-07 | 2007-08-09 | Astrazeneca Ab | Therapeutic agents I |
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| EP1924553A1 (en) * | 2005-08-08 | 2008-05-28 | Argenta Discovery Limited | Bicyclo[2.2.]hept-7-ylamine derivatives and their uses |
| JP2009504628A (ja) | 2005-08-10 | 2009-02-05 | ファイザー・リミテッド | オキシトシン拮抗薬としての置換トリアゾール誘導体 |
| US8026234B2 (en) * | 2007-09-25 | 2011-09-27 | Takeda Pharmaceutical Company Limited | Polo-like kinase inhibitors |
| CN102892754A (zh) * | 2010-03-17 | 2013-01-23 | 埃克希金医药品有限公司 | 芳基磺酰胺ccr3拮抗剂 |
| EP2604601B1 (en) * | 2010-08-10 | 2016-02-24 | Astellas Pharma Inc. | Hetero ring compound |
| AR084457A1 (es) * | 2010-12-22 | 2013-05-15 | Lundbeck & Co As H | Derivados de biciclo[3,2,1]octilamida |
| WO2014144952A2 (en) * | 2013-03-15 | 2014-09-18 | Peter Walter | Modulators of the eif2alpha pathway |
| WO2015038778A1 (en) * | 2013-09-11 | 2015-03-19 | The Brigham And Women's Hospital, Inc. | SUBSTITUTED UREA EIF2α KINASE ACTIVATORS |
| RS58175B1 (sr) * | 2014-04-04 | 2019-03-29 | Syros Pharmaceuticals Inc | Inhibitori ciklin-zavisne kinaze 7 (cdk7) |
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