JP2019515042A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019515042A5 JP2019515042A5 JP2019510574A JP2019510574A JP2019515042A5 JP 2019515042 A5 JP2019515042 A5 JP 2019515042A5 JP 2019510574 A JP2019510574 A JP 2019510574A JP 2019510574 A JP2019510574 A JP 2019510574A JP 2019515042 A5 JP2019515042 A5 JP 2019515042A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- alkyl
- compound
- independently
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021067440A JP2021107415A (ja) | 2016-05-05 | 2021-04-13 | 統合ストレス経路のモジュレーター |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662332284P | 2016-05-05 | 2016-05-05 | |
| US62/332,284 | 2016-05-05 | ||
| PCT/US2017/031352 WO2017193030A1 (en) | 2016-05-05 | 2017-05-05 | Modulators of the integrated stress pathway |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021067440A Division JP2021107415A (ja) | 2016-05-05 | 2021-04-13 | 統合ストレス経路のモジュレーター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019515042A JP2019515042A (ja) | 2019-06-06 |
| JP2019515042A5 true JP2019515042A5 (OSRAM) | 2020-06-25 |
| JP6869331B2 JP6869331B2 (ja) | 2021-05-12 |
Family
ID=58710114
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019510574A Expired - Fee Related JP6869331B2 (ja) | 2016-05-05 | 2017-05-05 | 統合ストレス経路のモジュレーター |
| JP2021067440A Pending JP2021107415A (ja) | 2016-05-05 | 2021-04-13 | 統合ストレス経路のモジュレーター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021067440A Pending JP2021107415A (ja) | 2016-05-05 | 2021-04-13 | 統合ストレス経路のモジュレーター |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10864196B2 (OSRAM) |
| EP (2) | EP3452454B1 (OSRAM) |
| JP (2) | JP6869331B2 (OSRAM) |
| CN (1) | CN109641853A (OSRAM) |
| AR (1) | AR108394A1 (OSRAM) |
| AU (1) | AU2017260363B2 (OSRAM) |
| CA (1) | CA3023161A1 (OSRAM) |
| ES (1) | ES2821790T3 (OSRAM) |
| PT (1) | PT3452454T (OSRAM) |
| TW (1) | TW201808914A (OSRAM) |
| UY (1) | UY37231A (OSRAM) |
| WO (1) | WO2017193030A1 (OSRAM) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10357493B2 (en) | 2017-03-10 | 2019-07-23 | Selenity Therapeutics (Bermuda), Ltd. | Metalloenzyme inhibitor compounds |
| CN108809583B (zh) | 2017-05-05 | 2024-03-26 | 华为技术有限公司 | 传输信号的方法和装置 |
| BR112019024155A2 (pt) * | 2017-05-15 | 2020-06-02 | Recurium Ip Holdings, Llc | Compostos analgésicos |
| CA3066328A1 (en) * | 2017-06-07 | 2018-12-13 | Glaxosmithkline Intellectual Property Development Limited | Chemical compounds as atf4 pathway inhibitors |
| WO2018225093A1 (en) * | 2017-06-07 | 2018-12-13 | Glaxosmithkline Intellectual Property Development Limited | Chemical compounds as atf4 pathway inhibitors |
| MY201438A (en) * | 2017-08-09 | 2024-02-22 | Denali Therapeutics Inc | Compounds, compositions and methods |
| PT3676297T (pt) | 2017-09-01 | 2023-08-29 | Denali Therapeutics Inc | Compostos, composições e métodos |
| BR112020008825A2 (pt) * | 2017-11-02 | 2020-10-20 | Calico Life Sciences Llc | moduladores da via de estresse integrada |
| CN112154142B (zh) * | 2017-11-02 | 2023-11-21 | 卡里科生命科学有限责任公司 | 整合应激通路的调节剂 |
| IL274406B2 (en) * | 2017-11-02 | 2024-04-01 | Calico Life Sciences Llc | Combined pressure pathway modulators |
| EP3704115A1 (en) | 2017-11-02 | 2020-09-09 | Calico Life Sciences LLC | Modulators of the integrated stress pathway |
| BR112020011914A2 (pt) | 2017-12-13 | 2020-11-24 | Praxis Biotech LLC | inibidores de via de resposta de tensão integrada |
| EP3768660A1 (en) * | 2018-03-23 | 2021-01-27 | Denali Therapeutics Inc. | Modulators of eukaryotic initiation factor 2 |
| JP2021527044A (ja) | 2018-06-05 | 2021-10-11 | プラクシス バイオテック エルエルシー | 統合的ストレス応答経路の阻害剤 |
| EP3849979A1 (en) | 2018-09-12 | 2021-07-21 | Novartis AG | Antiviral pyridopyrazinedione compounds |
| TWI832295B (zh) | 2018-10-11 | 2024-02-11 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| MA54959A (fr) | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
| WO2020168011A1 (en) * | 2019-02-13 | 2020-08-20 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| EP3959198A1 (en) | 2019-04-23 | 2022-03-02 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| WO2020216764A1 (en) | 2019-04-23 | 2020-10-29 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| US20200347043A1 (en) | 2019-04-30 | 2020-11-05 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| CN114466654A (zh) | 2019-06-12 | 2022-05-10 | 普拉西斯生物技术有限责任公司 | 整合应激反应通路调节剂 |
| TW202535873A (zh) | 2019-09-26 | 2025-09-16 | 瑞士商諾華公司 | 抗病毒吡唑并吡啶酮化合物 |
| US11752149B2 (en) | 2019-12-02 | 2023-09-12 | Pipeline Therapeutics, Inc. | Muscarinic acetylcholine M1 receptor antagonists |
| CR20220325A (es) | 2019-12-20 | 2022-08-19 | Tenaya Therapeutics Inc | Fluoroalquil-oxadiazoles y sus usos |
| IL294805A (en) | 2020-01-28 | 2022-09-01 | Evotec Int Gmbh | Modulators of the integrated stress response pathway |
| US12441720B2 (en) | 2020-03-11 | 2025-10-14 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| IL302170A (en) | 2020-10-22 | 2023-06-01 | Evotec Int Gmbh | Modulators of the integrated stress response pathway |
| EP4232447A1 (en) | 2020-10-22 | 2023-08-30 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| KR20230110509A (ko) | 2020-10-22 | 2023-07-24 | 에보텍 인터내셔널 게엠베하 | 통합 스트레스 반응 경로의 조절제 |
| KR20240016950A (ko) | 2021-05-04 | 2024-02-06 | 테나야 테라퓨틱스, 인코포레이티드 | 대사 질환 및 hfpef의 치료에 사용하기 위한 2-플루오로알킬-1,3,4-옥사디아졸-5-일-티아졸, hdac6 억제제 |
| EP4624458A1 (en) * | 2022-11-21 | 2025-10-01 | Shenzhen Zhongge Biological Technology Co., Ltd. | Compound, pharmaceutical composition containing same, synthesis method therefor and use thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5212A (en) | 1847-07-31 | Richard m | ||
| US162A (en) | 1837-04-17 | Island | ||
| US4911920A (en) | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| ATE141502T1 (de) | 1991-01-15 | 1996-09-15 | Alcon Lab Inc | Verwendung von karrageenan in topischen ophthalmologischen zusammensetzungen |
| JO2397B1 (en) * | 2002-12-20 | 2007-06-17 | ميرك شارب اند دوم كوربوريشن | Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors |
| CN100471854C (zh) * | 2002-12-20 | 2009-03-25 | 麦克公司 | 用作11-β-羟基类固醇脱氢酶-1抑制剂的三唑衍生物 |
| EP1706384A1 (en) | 2004-01-07 | 2006-10-04 | AstraZeneca AB | Therapeutic agents i |
| CN102816081A (zh) | 2005-01-05 | 2012-12-12 | 雅培制药有限公司 | 11-β-羟甾类脱氢酶1型酶的抑制剂 |
| EP2281813A1 (en) | 2005-08-08 | 2011-02-09 | Pulmagen Therapeutics (Synergy) Limited | Bicyclo[2.2.1]hept-7-ylamine derivatives and their uses |
| EP1954287B2 (en) * | 2005-10-31 | 2016-02-24 | Merck Sharp & Dohme Corp. | Cetp inhibitors |
| WO2011087758A1 (en) | 2009-12-22 | 2011-07-21 | H. Lundbeck A/S | Adamantyl amide derivatives and uses of same |
| TWI538905B (zh) | 2010-12-22 | 2016-06-21 | Ｈ 朗德貝克公司 | 雙環［３．２．１］辛基醯胺衍生物及其用途 |
| WO2014144952A2 (en) | 2013-03-15 | 2014-09-18 | Peter Walter | Modulators of the eif2alpha pathway |
| WO2015038778A1 (en) * | 2013-09-11 | 2015-03-19 | The Brigham And Women's Hospital, Inc. | SUBSTITUTED UREA EIF2α KINASE ACTIVATORS |
| US10526294B2 (en) * | 2016-06-24 | 2020-01-07 | Mersana Therapeutics, Inc. | Pyrrolobenzodiazepines and conjugates thereof |
-
2017
- 2017-05-04 TW TW106114862A patent/TW201808914A/zh unknown
- 2017-05-05 EP EP17724205.4A patent/EP3452454B1/en active Active
- 2017-05-05 UY UY0001037231A patent/UY37231A/es not_active Application Discontinuation
- 2017-05-05 AR ARP170101182A patent/AR108394A1/es unknown
- 2017-05-05 AU AU2017260363A patent/AU2017260363B2/en not_active Expired - Fee Related
- 2017-05-05 US US16/098,950 patent/US10864196B2/en active Active
- 2017-05-05 EP EP20184319.0A patent/EP3778575A1/en not_active Withdrawn
- 2017-05-05 CA CA3023161A patent/CA3023161A1/en not_active Abandoned
- 2017-05-05 CN CN201780042067.3A patent/CN109641853A/zh active Pending
- 2017-05-05 PT PT177242054T patent/PT3452454T/pt unknown
- 2017-05-05 WO PCT/US2017/031352 patent/WO2017193030A1/en not_active Ceased
- 2017-05-05 JP JP2019510574A patent/JP6869331B2/ja not_active Expired - Fee Related
- 2017-05-05 ES ES17724205T patent/ES2821790T3/es active Active
-
2020
- 2020-05-28 US US16/885,766 patent/US20210113532A1/en not_active Abandoned
-
2021
- 2021-04-13 JP JP2021067440A patent/JP2021107415A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019515042A5 (OSRAM) | ||
| JP2019519599A5 (OSRAM) | ||
| JP2019515043A5 (OSRAM) | ||
| JP2019530649A5 (OSRAM) | ||
| RU2022106770A (ru) | Модуляторы интегрированного сигнального пути стресса | |
| AU765473B2 (en) | 5-pyridyl-1,3-azole compounds, process for producing the same and use thereof | |
| JP2013525433A5 (OSRAM) | ||
| WO2015101928A1 (en) | Fused thiophene and thiazole derivatives as ror gamma modulators | |
| TWI803525B (zh) | 作為PI3K-γ 抑制劑之三級醇 | |
| CN114729044B (zh) | 毒蕈碱型乙酰胆碱m1受体拮抗剂 | |
| CA2966164C (en) | Substituted dihydropyrrolopyrazole compound | |
| AU2019217320B2 (en) | Steroid derivative regulators, method for preparing the same, and uses thereof | |
| JP2019508407A5 (OSRAM) | ||
| AU2004215481A1 (en) | Pyrazolo(1,5-A)pyrimidine derivatives | |
| JP2009534407A5 (OSRAM) | ||
| JP2021501781A5 (OSRAM) | ||
| JP2017502088A5 (OSRAM) | ||
| JP2009534406A5 (OSRAM) | ||
| RU2017138537A (ru) | Новые гибридные ActRIIB белки-ловушки лигандов для лечения заболеваний, связанных с мышечной атрофией | |
| JP2017538712A5 (OSRAM) | ||
| DE69414085T2 (de) | Wirkstoff zum schutze von gehirnzellen | |
| AU2019389017B2 (en) | Methods of treating disease with MAGL inhibitors | |
| CA3043612A1 (en) | Magl inhibitors | |
| JPWO2020223536A5 (OSRAM) | ||
| RS50443B (sr) | Derivati aminotiazola i njihova primena kao liganada crf receptora |