JP2019514872A5 - - Google Patents
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- Publication number
- JP2019514872A5 JP2019514872A5 JP2018554716A JP2018554716A JP2019514872A5 JP 2019514872 A5 JP2019514872 A5 JP 2019514872A5 JP 2018554716 A JP2018554716 A JP 2018554716A JP 2018554716 A JP2018554716 A JP 2018554716A JP 2019514872 A5 JP2019514872 A5 JP 2019514872A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- nash
- use according
- formula
- nafld
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662326435P | 2016-04-22 | 2016-04-22 | |
| US62/326,435 | 2016-04-22 | ||
| US201662395436P | 2016-09-16 | 2016-09-16 | |
| US62/395,436 | 2016-09-16 | ||
| PCT/US2017/028529 WO2017184819A1 (en) | 2016-04-22 | 2017-04-20 | Nalmefene, naltrexone or derivatives thereof for use in treating (non)-alcoholic steatohepatitis or non-alcoholic fatty liver disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019514872A JP2019514872A (ja) | 2019-06-06 |
| JP2019514872A5 true JP2019514872A5 (enExample) | 2020-03-05 |
Family
ID=58668969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018554716A Pending JP2019514872A (ja) | 2016-04-22 | 2017-04-20 | （非）アルコ−ル性脂肪肝炎又は非アルコ−ル性脂肪性肝疾患の治療のためのナルメフェン（ＮＡＬＭＥＦＥＮＥ）、ナルトレキソン（ｎａｌｔｒｅｘｏｎｅ）及びその関連誘導体の応用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10045977B2 (enExample) |
| EP (1) | EP3445363A1 (enExample) |
| JP (1) | JP2019514872A (enExample) |
| KR (1) | KR20180129909A (enExample) |
| CN (2) | CN109069503A (enExample) |
| AU (1) | AU2017253228B2 (enExample) |
| BR (1) | BR112018071705A2 (enExample) |
| CA (1) | CA3021788C (enExample) |
| RU (1) | RU2717677C1 (enExample) |
| WO (1) | WO2017184819A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011140441A2 (en) | 2010-05-06 | 2011-11-10 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| EP3712254A1 (en) | 2014-05-28 | 2020-09-23 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| CA2963704A1 (en) | 2014-10-17 | 2016-04-21 | Children's Hospital Medical Center | In vivo model of human small intestine using pluripotent stem cells and methods of making and using same |
| EP4177335A1 (en) | 2016-05-05 | 2023-05-10 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
| US20190247373A1 (en) * | 2016-07-14 | 2019-08-15 | Children's Hospital Medical Center | Methods for treating fibrosis |
| SG11201903697WA (en) | 2016-11-04 | 2019-05-30 | Childrens Hospital Med Ct | Liver organoid compositions and methods of making and using same |
| EP3548507A4 (en) | 2016-12-05 | 2020-07-15 | Children's Hospital Medical Center | COLON ORGANOIDS AND PROCESSES FOR THE PREPARATION AND USE THEREOF |
| EP3609997A4 (en) | 2017-04-14 | 2021-03-03 | Children's Hospital Medical Center | COMPOSITIONS OF STEM CELLS FROM MULTIPLE DONOR CELLS AND THEIR PREPARATION PROCEDURES |
| US12297457B2 (en) | 2017-10-10 | 2025-05-13 | Children's Hospital Medical Center | Esophageal tissue and/or organoid compositions and methods of making same |
| EP3727394A4 (en) | 2017-12-21 | 2021-09-08 | Children's Hospital Medical Center | DIGITALIZED HUMAN ORGANOIDS AND METHOD OF USING THEREOF |
| US12421500B2 (en) | 2018-07-26 | 2025-09-23 | Children's Hospital Medical Center | Hepato-biliary-pancreatic tissues and methods of making same |
| JP2021535753A (ja) | 2018-09-12 | 2021-12-23 | チルドレンズ ホスピタル メディカル センター | 造血幹細胞およびその派生体の生成のためのオルガノイド組成物 |
| WO2020160371A1 (en) | 2019-02-01 | 2020-08-06 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| CA3141814A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| CN114174494A (zh) | 2019-05-31 | 2022-03-11 | 儿童医院医学中心 | 产生和扩增造血干细胞的方法 |
| CA3236690A1 (en) | 2021-11-18 | 2023-05-25 | Ju Hee Kim | Sustained-release injectable composition containing naltrexone and method for preparing same |
| CN118234488A (zh) | 2021-11-18 | 2024-06-21 | 创技公司株式会社 | 包含难溶性药物的微粒的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5086058A (en) * | 1990-06-04 | 1992-02-04 | Alko Ltd. | Method for treating alcoholism with nalmefene |
| AU2003234621A1 (en) | 2002-05-17 | 2003-12-02 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7923454B2 (en) * | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US8017622B2 (en) * | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US10363251B2 (en) * | 2009-07-16 | 2019-07-30 | Mallinckrodt Llc | (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof |
| TR201002473A2 (tr) * | 2010-03-31 | 2011-09-21 | Mustafa Nevzat �La� Sanay�� A.�. | Herpes zoster hastalığının bır opiat reseptör antagonist kullanılarak tedavi yöntemi. |
| CN102048733B (zh) | 2010-12-23 | 2011-12-28 | 武汉同源药业有限公司 | 盐酸纳美芬在制备治疗脂肪肝的药物中的用途 |
| MY180160A (en) * | 2013-04-22 | 2020-11-23 | Cadila Healthcare Ltd | A novel composition for nonalcoholic fatty liver disease (nafld) |
| EP3416619A2 (en) * | 2016-02-18 | 2018-12-26 | Immune Therapeutics, Inc. | Method for inducing a sustained immune response |
-
2017
- 2017-04-20 CN CN201780024846.0A patent/CN109069503A/zh active Pending
- 2017-04-20 EP EP17721252.9A patent/EP3445363A1/en not_active Ceased
- 2017-04-20 CA CA3021788A patent/CA3021788C/en active Active
- 2017-04-20 CN CN202311054107.XA patent/CN117137917A/zh active Pending
- 2017-04-20 WO PCT/US2017/028529 patent/WO2017184819A1/en not_active Ceased
- 2017-04-20 RU RU2018136387A patent/RU2717677C1/ru active
- 2017-04-20 AU AU2017253228A patent/AU2017253228B2/en active Active
- 2017-04-20 JP JP2018554716A patent/JP2019514872A/ja active Pending
- 2017-04-20 KR KR1020187031996A patent/KR20180129909A/ko not_active Ceased
- 2017-04-20 US US15/492,198 patent/US10045977B2/en active Active
- 2017-04-20 BR BR112018071705-3A patent/BR112018071705A2/pt not_active IP Right Cessation
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