JP2019514872A5 - - Google Patents
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- JP2019514872A5 JP2019514872A5 JP2018554716A JP2018554716A JP2019514872A5 JP 2019514872 A5 JP2019514872 A5 JP 2019514872A5 JP 2018554716 A JP2018554716 A JP 2018554716A JP 2018554716 A JP2018554716 A JP 2018554716A JP 2019514872 A5 JP2019514872 A5 JP 2019514872A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- nash
- use according
- formula
- nafld
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662326435P | 2016-04-22 | 2016-04-22 | |
| US62/326,435 | 2016-04-22 | ||
| US201662395436P | 2016-09-16 | 2016-09-16 | |
| US62/395,436 | 2016-09-16 | ||
| PCT/US2017/028529 WO2017184819A1 (en) | 2016-04-22 | 2017-04-20 | Nalmefene, naltrexone or derivatives thereof for use in treating (non)-alcoholic steatohepatitis or non-alcoholic fatty liver disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019514872A JP2019514872A (ja) | 2019-06-06 |
| JP2019514872A5 true JP2019514872A5 (cg-RX-API-DMAC7.html) | 2020-03-05 |
Family
ID=58668969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018554716A Pending JP2019514872A (ja) | 2016-04-22 | 2017-04-20 | （非）アルコ−ル性脂肪肝炎又は非アルコ−ル性脂肪性肝疾患の治療のためのナルメフェン（ＮＡＬＭＥＦＥＮＥ）、ナルトレキソン（ｎａｌｔｒｅｘｏｎｅ）及びその関連誘導体の応用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10045977B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3445363A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2019514872A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20180129909A (cg-RX-API-DMAC7.html) |
| CN (2) | CN117137917A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017253228B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112018071705A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3021788C (cg-RX-API-DMAC7.html) |
| RU (1) | RU2717677C1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017184819A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011140441A2 (en) | 2010-05-06 | 2011-11-10 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| ES2860423T3 (es) | 2014-05-28 | 2021-10-05 | Childrens Hospital Med Ct | Métodos y sistemas para convertir células precursoras en tejidos gástricos mediante diferenciación dirigida |
| WO2016061464A1 (en) | 2014-10-17 | 2016-04-21 | Children's Hospital Center, D/B/A Cincinnati Children's Hospital Medical Center | In vivo model of human small intetine using pluripotent stem cells and methods of making and using same |
| JP6963882B2 (ja) | 2016-05-05 | 2021-11-10 | チルドレンズ ホスピタル メディカル センター | 胃底部組織のインビトロでの製造のための方法及び当該方法と関連した組成物 |
| CN109475626A (zh) * | 2016-07-14 | 2019-03-15 | 儿童医院医疗中心 | 治疗纤维化的方法 |
| EP3534907A4 (en) | 2016-11-04 | 2020-06-24 | Children's Hospital Medical Center | COMPOSITIONS AND METHODS FOR TREATING HEPATIC DISEASE |
| EP3548507A4 (en) | 2016-12-05 | 2020-07-15 | Children's Hospital Medical Center | COLON ORGANOIDS AND PROCESSES FOR THE PREPARATION AND USE THEREOF |
| EP3609997A4 (en) | 2017-04-14 | 2021-03-03 | Children's Hospital Medical Center | COMPOSITIONS OF STEM CELLS FROM MULTIPLE DONOR CELLS AND THEIR PREPARATION PROCEDURES |
| CA3077442A1 (en) | 2017-10-10 | 2019-04-18 | Children's Hospital Medical Center | Esophageal tissue and/or organoid compositions and methods of making same |
| WO2019126626A1 (en) | 2017-12-21 | 2019-06-27 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| SG11202100533VA (en) | 2018-07-26 | 2021-02-25 | Childrens Hospital Med Ct | Hepato-biliary-pancreatic tissues and methods of making same |
| CA3112026A1 (en) | 2018-09-12 | 2020-03-19 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| US12497597B2 (en) | 2019-05-31 | 2025-12-16 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| KR20230073125A (ko) | 2021-11-18 | 2023-05-25 | (주)인벤티지랩 | 난용성 약물을 포함하는 마이크로 입자의 제조 방법 |
| AU2022394933A1 (en) | 2021-11-18 | 2024-05-09 | Inventage Lab Inc. | Sustained-release injectable composition containing naltrexone and method for preparing same |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5086058A (en) * | 1990-06-04 | 1992-02-04 | Alko Ltd. | Method for treating alcoholism with nalmefene |
| US7923454B2 (en) * | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| MXPA04011327A (es) | 2002-05-17 | 2005-08-15 | Jenken Biosciences Inc | Opioides y compuestos similares a opioides y usos de los mismos. |
| US8017622B2 (en) * | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US10363251B2 (en) * | 2009-07-16 | 2019-07-30 | Mallinckrodt Llc | (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof |
| TR201002473A2 (tr) * | 2010-03-31 | 2011-09-21 | Mustafa Nevzat �La� Sanay�� A.�. | Herpes zoster hastalığının bır opiat reseptör antagonist kullanılarak tedavi yöntemi. |
| CN102048733B (zh) * | 2010-12-23 | 2011-12-28 | 武汉同源药业有限公司 | 盐酸纳美芬在制备治疗脂肪肝的药物中的用途 |
| JP6246895B2 (ja) * | 2013-04-22 | 2017-12-13 | カディラ・ヘルスケア・リミテッド | 非アルコール性脂肪性肝疾患（ｎａｆｌｄ）のための新規組成物 |
| EP3416619A2 (en) * | 2016-02-18 | 2018-12-26 | Immune Therapeutics, Inc. | Method for inducing a sustained immune response |
-
2017
- 2017-04-20 WO PCT/US2017/028529 patent/WO2017184819A1/en not_active Ceased
- 2017-04-20 CN CN202311054107.XA patent/CN117137917A/zh active Pending
- 2017-04-20 EP EP17721252.9A patent/EP3445363A1/en not_active Ceased
- 2017-04-20 KR KR1020187031996A patent/KR20180129909A/ko not_active Ceased
- 2017-04-20 US US15/492,198 patent/US10045977B2/en active Active
- 2017-04-20 JP JP2018554716A patent/JP2019514872A/ja active Pending
- 2017-04-20 BR BR112018071705-3A patent/BR112018071705A2/pt not_active IP Right Cessation
- 2017-04-20 CA CA3021788A patent/CA3021788C/en active Active
- 2017-04-20 RU RU2018136387A patent/RU2717677C1/ru active
- 2017-04-20 CN CN201780024846.0A patent/CN109069503A/zh active Pending
- 2017-04-20 AU AU2017253228A patent/AU2017253228B2/en active Active
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