JP2019514411A5 - - Google Patents

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Publication number
JP2019514411A5
JP2019514411A5 JP2018559273A JP2018559273A JP2019514411A5 JP 2019514411 A5 JP2019514411 A5 JP 2019514411A5 JP 2018559273 A JP2018559273 A JP 2018559273A JP 2018559273 A JP2018559273 A JP 2018559273A JP 2019514411 A5 JP2019514411 A5 JP 2019514411A5
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JP
Japan
Prior art keywords
recombinant protein
protein
antigen
altered
galactosylation
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Application number
JP2018559273A
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English (en)
Japanese (ja)
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JP6882339B2 (ja
JP2019514411A (ja
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Priority claimed from PCT/EP2017/061181 external-priority patent/WO2017194605A1/en
Publication of JP2019514411A publication Critical patent/JP2019514411A/ja
Publication of JP2019514411A5 publication Critical patent/JP2019514411A5/ja
Application granted granted Critical
Publication of JP6882339B2 publication Critical patent/JP6882339B2/ja
Expired - Fee Related legal-status Critical Current
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JP2018559273A 2016-05-10 2017-05-10 ペルアセチルガラクトースを使った組換えタンパク質のタンパク質ガラクトシル化プロファイルを改変する方法 Expired - Fee Related JP6882339B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16169062.3 2016-05-10
EP16169062 2016-05-10
PCT/EP2017/061181 WO2017194605A1 (en) 2016-05-10 2017-05-10 Methods for modulating protein galactosylation profiles of recombinant proteins using peracetyl galactose

Publications (3)

Publication Number Publication Date
JP2019514411A JP2019514411A (ja) 2019-06-06
JP2019514411A5 true JP2019514411A5 (https=) 2020-06-18
JP6882339B2 JP6882339B2 (ja) 2021-06-02

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ID=56026651

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018559273A Expired - Fee Related JP6882339B2 (ja) 2016-05-10 2017-05-10 ペルアセチルガラクトースを使った組換えタンパク質のタンパク質ガラクトシル化プロファイルを改変する方法

Country Status (9)

Country Link
US (1) US11118208B2 (https=)
EP (1) EP3455363B1 (https=)
JP (1) JP6882339B2 (https=)
CN (1) CN109072273B (https=)
AU (2) AU2017264541A1 (https=)
CA (1) CA3022769A1 (https=)
ES (1) ES2908067T3 (https=)
IL (1) IL262875B (https=)
WO (1) WO2017194605A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3397282A4 (en) 2015-12-30 2019-08-07 Momenta Pharmaceuticals, Inc. METHODS RELATING TO BIOLOGICA
WO2018119142A1 (en) 2016-12-21 2018-06-28 Amgen Inc. Anti-tnf alpha antibody formulations
US12595454B2 (en) 2018-09-06 2026-04-07 Momenta Pharmaceuticals, Inc. Methods of continuous cell culture
IL284374B2 (en) * 2018-12-31 2025-10-01 Momenta Pharmaceuticals Inc Methods for producing ozatekinumab
CN113549667A (zh) * 2021-07-21 2021-10-26 杭州奕安济世生物药业有限公司 一种降低抗体半乳糖基化的方法
AU2023223660A1 (en) * 2022-02-25 2024-08-01 Kashiv Biosciences, Llc A process for improving polypeptide expression in mammalian cell culture
CN121058875A (zh) * 2025-10-11 2025-12-05 广东海洋大学 一种负载脂溶性多酚的碱诱导糖基化罗非鱼蛋白水解物及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009135181A2 (en) * 2008-05-02 2009-11-05 Seattle Genetics, Inc. Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation
RU2625768C2 (ru) 2010-08-05 2017-07-18 Сиэтл Дженетикс, Инк. Способы ингибирования фукозилирования белков in vivo с использованием аналогов фукозы
RU2642285C1 (ru) * 2014-01-29 2018-01-24 ЭлДжи КЕМ, ЛТД. Способ получения целевого антитела с модулированным галактозилированием (варианты) и способ модулирования галактозилирования целевого антитела (варианты) путем оптимизации культуральной среды
US20160039924A1 (en) * 2014-08-05 2016-02-11 Abbvie Inc. Methods for modulating the glycosylation profile of recombinant proteins using dissolved oxygen

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