JP2019509999A5 - - Google Patents
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- JP2019509999A5 JP2019509999A5 JP2018543712A JP2018543712A JP2019509999A5 JP 2019509999 A5 JP2019509999 A5 JP 2019509999A5 JP 2018543712 A JP2018543712 A JP 2018543712A JP 2018543712 A JP2018543712 A JP 2018543712A JP 2019509999 A5 JP2019509999 A5 JP 2019509999A5
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- JP
- Japan
- Prior art keywords
- asc
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 102000004127 Cytokines Human genes 0.000 claims 4
- 108090000695 Cytokines Proteins 0.000 claims 4
- 239000001963 growth medium Substances 0.000 claims 3
- 230000000770 proinflammatory effect Effects 0.000 claims 3
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 102000008070 Interferon-gamma Human genes 0.000 claims 2
- 108010074328 Interferon-gamma Proteins 0.000 claims 2
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 2
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 229960003130 interferon gamma Drugs 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 239000002609 medium Substances 0.000 claims 2
- MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 claims 1
- 239000004826 Synthetic adhesive Substances 0.000 claims 1
- 238000004115 adherent culture Methods 0.000 claims 1
- 230000001464 adherent effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000001605 fetal effect Effects 0.000 claims 1
- 238000011534 incubation Methods 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 230000008774 maternal effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 210000005059 placental tissue Anatomy 0.000 claims 1
- 210000002536 stromal cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662296621P | 2016-02-18 | 2016-02-18 | |
| US62/296,621 | 2016-02-18 | ||
| PCT/IB2017/050868 WO2017141181A1 (en) | 2016-02-18 | 2017-02-16 | Methods and compositions for treating cancers and neoplasms |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019509999A JP2019509999A (ja) | 2019-04-11 |
| JP2019509999A5 true JP2019509999A5 (cg-RX-API-DMAC7.html) | 2020-03-26 |
| JP6884792B2 JP6884792B2 (ja) | 2021-06-09 |
Family
ID=58266008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018543712A Active JP6884792B2 (ja) | 2016-02-18 | 2017-02-16 | がん及び新生物の治療方法及び治療用組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210205370A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3416662B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6884792B2 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017220148A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3012741A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL261146B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017141181A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018251898A1 (en) | 2017-04-13 | 2019-10-31 | Senti Biosciences, Inc. | Combinatorial cancer immunotherapy |
| WO2019169141A1 (en) * | 2018-02-28 | 2019-09-06 | Lester Smith Medical Research Institute | Production and use of extracellular vesicles |
| WO2019186471A1 (en) * | 2018-03-28 | 2019-10-03 | Pluristem Ltd. | Methods for expanding adherent stromal cells and cells obtained thereby |
| CA3098514A1 (en) * | 2018-04-30 | 2019-11-14 | Children's Medical Center Corporation | Mesenchymal stromal cell exosomes and uses thereof |
| JP2022512766A (ja) * | 2018-10-17 | 2022-02-07 | センティ バイオサイエンシズ インコーポレイテッド | 組み合わせがん免疫療法 |
| US11419898B2 (en) | 2018-10-17 | 2022-08-23 | Senti Biosciences, Inc. | Combinatorial cancer immunotherapy |
| EP4031145A4 (en) * | 2019-09-06 | 2023-07-26 | Mantra Bio, Inc. | EXTRACELLULAR VESICLE FENRETINIDE COMPOSITIONS, EXTRACELLULAR VESICLE C-KIT INHIBITOR COMPOSITIONS, METHOD OF PREPARATION AND USES THEREOF |
| EP4214714A4 (en) * | 2020-09-21 | 2024-10-16 | Mestastop Solutions Private Limited | SYSTEMS AND METHODS FOR PREDICTING CANCER METASTASIS AND DRUG SCREENING |
| WO2023044902A1 (zh) * | 2021-09-27 | 2023-03-30 | 金涌长生医学生物科技股份有限公司 | 一种蜕膜胎盘间充质干细胞及其在制备促进血管新生药物组合物中的用途 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5902741A (en) | 1986-04-18 | 1999-05-11 | Advanced Tissue Sciences, Inc. | Three-dimensional cartilage cultures |
| JPS6410979A (en) | 1987-07-03 | 1989-01-13 | Mitsubishi Chem Ind | Microcarrier for cultivating cell |
| US5629186A (en) | 1994-04-28 | 1997-05-13 | Lockheed Martin Corporation | Porous matrix and method of its production |
| US6132463A (en) | 1995-05-19 | 2000-10-17 | Etex Corporation | Cell seeding of ceramic compositions |
| DE69903800T2 (de) | 1998-03-18 | 2003-10-02 | Massachusetts Institute Of Technology, Cambridge | Vaskularisierte perfundierte anordnungen für mikrogewebe und mikroorgane |
| US6153432A (en) | 1999-01-29 | 2000-11-28 | Zen-Bio, Inc | Methods for the differentiation of human preadipocytes into adipocytes |
| CA2400485C (en) | 2000-02-26 | 2014-04-29 | Artecel Sciences, Inc. | Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof |
| WO2007011693A2 (en) * | 2005-07-14 | 2007-01-25 | Medistem Laboratories, Inc. | Compositions of placentally-derived stem cells for the treatment of cancer |
| WO2011132087A1 (en) * | 2010-04-23 | 2011-10-27 | Pluristem Ltd. | Adherent stromal cells derived from plancentas of multiple donors and uses thereof |
| PT2626417E (pt) | 2006-03-23 | 2015-11-16 | Pluristem Ltd | Métodos para expansão celular e usos de células e de meios condicionados produzidos através deles para terapia |
| US7531334B2 (en) | 2006-04-14 | 2009-05-12 | Xerox Corporation | Polymeric microcarriers for cell culture functions |
| US7993918B2 (en) * | 2006-08-04 | 2011-08-09 | Anthrogenesis Corporation | Tumor suppression using placental stem cells |
| PT2200622E (pt) * | 2007-09-19 | 2012-11-06 | Pluristem Ltd | Células aderentes provenientes de tecido adiposo ou placentário e respetiva utilização terapêutica |
| AU2008307633C1 (en) * | 2007-09-28 | 2015-04-30 | Celularity Inc. | Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells |
| US8828720B2 (en) | 2008-03-17 | 2014-09-09 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
| EP2334783B1 (en) * | 2008-09-02 | 2016-06-22 | Pluristem Ltd. | Adherent cells from placenta tissue and use thereof in therapy |
| EP2451943B1 (en) | 2009-07-09 | 2016-11-23 | TiGenix, S.A.U. | Methods and compositions for use in cellular therapies |
| EP2977445B1 (en) | 2009-11-30 | 2018-07-25 | Pluristem Ltd. | Adherent cells from placenta and use of same in disease treatment |
| CA2787992A1 (en) * | 2010-01-26 | 2011-08-04 | Anthrogenesis Corporation | Treatment of bone-related cancers using placental stem cells |
| ES2768296T3 (es) | 2011-04-15 | 2020-06-22 | Pluristem Ltd | Métodos y sistemas para recoger células |
| RU2615179C2 (ru) | 2012-09-06 | 2017-04-04 | Плуристем Лтд. | Устройства и способы культивирования клеток |
| US20150272992A1 (en) * | 2012-10-24 | 2015-10-01 | The Texas A&M University System | Treatment of Tumors with Activated Mesenchymal Stem Cells |
| US10258652B2 (en) | 2014-12-18 | 2019-04-16 | Pluristem Ltd. | Methods and compositions for treating and preventing muscle wasting disorders |
| IL294058A (en) | 2015-03-23 | 2022-08-01 | Pluristem Ltd | Use of adherent stromal cells for enhancing hematopoiesis in a subject in need thereof |
-
2017
- 2017-02-16 AU AU2017220148A patent/AU2017220148A1/en not_active Abandoned
- 2017-02-16 US US15/999,461 patent/US20210205370A1/en not_active Abandoned
- 2017-02-16 CA CA3012741A patent/CA3012741A1/en active Pending
- 2017-02-16 IL IL261146A patent/IL261146B/en unknown
- 2017-02-16 WO PCT/IB2017/050868 patent/WO2017141181A1/en not_active Ceased
- 2017-02-16 JP JP2018543712A patent/JP6884792B2/ja active Active
- 2017-02-16 EP EP17710054.2A patent/EP3416662B1/en active Active