JP2019509986A5 - - Google Patents

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JP2019509986A5
JP2019509986A5 JP2018540128A JP2018540128A JP2019509986A5 JP 2019509986 A5 JP2019509986 A5 JP 2019509986A5 JP 2018540128 A JP2018540128 A JP 2018540128A JP 2018540128 A JP2018540128 A JP 2018540128A JP 2019509986 A5 JP2019509986 A5 JP 2019509986A5
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Japan
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cancer
syndrome
disease
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JP2018540128A
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English (en)
Japanese (ja)
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JP2019509986A (ja
JP7042744B2 (ja
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Priority claimed from PCT/US2017/016527 external-priority patent/WO2017136739A1/en
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Publication of JP2019509986A5 publication Critical patent/JP2019509986A5/ja
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JP2018540128A 2016-02-04 2017-02-03 トリプトライドのグルコース・コンジュゲート、その類縁体及び使用 Active JP7042744B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662291416P 2016-02-04 2016-02-04
US62/291,416 2016-02-04
PCT/US2017/016527 WO2017136739A1 (en) 2016-02-04 2017-02-03 Glucose conjugates of triptolide, analogs and uses thereof

Publications (3)

Publication Number Publication Date
JP2019509986A JP2019509986A (ja) 2019-04-11
JP2019509986A5 true JP2019509986A5 (enExample) 2020-02-27
JP7042744B2 JP7042744B2 (ja) 2022-03-28

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JP2018540128A Active JP7042744B2 (ja) 2016-02-04 2017-02-03 トリプトライドのグルコース・コンジュゲート、その類縁体及び使用

Country Status (8)

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US (2) US10695319B2 (enExample)
EP (1) EP3411121B1 (enExample)
JP (1) JP7042744B2 (enExample)
CN (1) CN108601952B (enExample)
AU (1) AU2017214572A1 (enExample)
CA (1) CA3013619A1 (enExample)
MX (1) MX2018009406A (enExample)
WO (1) WO2017136739A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109942665B (zh) * 2018-04-02 2021-04-06 欣凯医药化工中间体(上海)有限公司 雷公藤内酯醇衍生物及其制备方法和应用
CN109897053B (zh) * 2019-03-28 2020-05-29 中国医学科学院医药生物技术研究所 雷斯吲哚甲及其制备方法和抗丙型肝炎病毒用途
CN111040018A (zh) * 2019-12-30 2020-04-21 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) 丙烯酸雷公藤甲素酯、其制备方法及其应用
EP4086271B1 (en) 2019-12-30 2023-12-13 Guangdong Provincial Hospital of TCM Triptolide acrylate, preparation method therefor and use thereof
EP4114468A4 (en) * 2020-03-02 2025-04-09 The Johns Hopkins University GLUCOSETRIPTOLIDE CONJUGATES AND USES THEREOF
JP2023538424A (ja) * 2020-08-21 2023-09-07 ルヤン コーポレイション トリプトリドコンジュゲートおよびその使用
CN115286684A (zh) * 2022-05-20 2022-11-04 福建医科大学 一种糖与雷公藤内酯醇或其衍生物的缀合物及其制备方法与应用
ES3035530T3 (en) 2023-03-09 2025-09-04 Minneamrita Therapeutics Llc Drug combination for the treatment of stomach cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6218367B1 (en) * 1998-09-15 2001-04-17 Organomed Corporation Paclitaxel-carbohydrate conjugates: design, synthesis and biological evaluations
US6620843B2 (en) 2001-01-19 2003-09-16 Pharmagenesis Anticancer treatment using triptolide prodrugs
CA2448795A1 (en) 2001-03-15 2002-09-26 Pharmagenesis, Inc. Amino acid derivatives of triptolide compounds as immune modulators and anticancer agent
US9150600B2 (en) * 2009-05-07 2015-10-06 Regents Of The University Of Minnesota Triptolide prodrugs

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