JP2022540333A5 - - Google Patents
Info
- Publication number
- JP2022540333A5 JP2022540333A5 JP2021576580A JP2021576580A JP2022540333A5 JP 2022540333 A5 JP2022540333 A5 JP 2022540333A5 JP 2021576580 A JP2021576580 A JP 2021576580A JP 2021576580 A JP2021576580 A JP 2021576580A JP 2022540333 A5 JP2022540333 A5 JP 2022540333A5
- Authority
- JP
- Japan
- Prior art keywords
- alkylene
- unsubstituted
- substituted
- cancer
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962872593P | 2019-07-10 | 2019-07-10 | |
| US62/872,593 | 2019-07-10 | ||
| PCT/US2020/041175 WO2021007307A1 (en) | 2019-07-10 | 2020-07-08 | Bcl-2 protein inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022540333A JP2022540333A (ja) | 2022-09-15 |
| JP2022540333A5 true JP2022540333A5 (enExample) | 2023-07-12 |
Family
ID=74114258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021576580A Ceased JP2022540333A (ja) | 2019-07-10 | 2020-07-08 | Ｂｃｌ－２タンパク質阻害剤 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20220265834A1 (enExample) |
| EP (1) | EP3972966A4 (enExample) |
| JP (1) | JP2022540333A (enExample) |
| KR (1) | KR20220034805A (enExample) |
| CN (1) | CN114144411A (enExample) |
| AR (1) | AR119379A1 (enExample) |
| AU (1) | AU2020310147A1 (enExample) |
| CA (1) | CA3140085A1 (enExample) |
| IL (1) | IL289622A (enExample) |
| MX (1) | MX2022000310A (enExample) |
| TW (1) | TW202116758A (enExample) |
| WO (1) | WO2021007307A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021167987A1 (en) * | 2020-02-21 | 2021-08-26 | Recurium Ip Holdings, Llc | Difluoromethyl iodo compounds and methods |
| US20230167105A1 (en) * | 2020-04-28 | 2023-06-01 | Recurium Ip Holdings, Llc | Bcl-2 protein inhibitors |
| JP2024505562A (ja) | 2021-02-02 | 2024-02-06 | レス ラボラトイレス セルビエル | 選択的ｂｃｌ－ｘｌ ｐｒｏｔａｃ化合物及び使用の方法 |
| WO2023215449A1 (en) | 2022-05-06 | 2023-11-09 | Treeline Biosciences, Inc. | Tetrahydroisoquinoline heterobifunctional bcl-xl degraders |
| EP4519259A1 (en) | 2022-05-06 | 2025-03-12 | Treeline Biosciences, Inc. | Tetrahydroisoquinoline heterobifunctional bcl-xl degraders |
| EP4519260A1 (en) | 2022-05-06 | 2025-03-12 | Treeline Biosciences, Inc. | Tetrahydroisoquinoline heterobifunctional bcl-xdegraders |
| TW202527930A (zh) | 2023-11-07 | 2025-07-16 | 美商樹線生物科學公司 | 四氫異喹啉異雙功能ｂｃｌ－ｘｌ降解劑 |
| TW202535872A (zh) | 2023-11-07 | 2025-09-16 | 美商樹線生物科學公司 | 四氫異喹啉異雙功能ｂｃｌ－ｘｌ降解劑 |
| WO2025101575A1 (en) | 2023-11-07 | 2025-05-15 | Treeline Biosciences, Inc. | Tetrahydroisoquinoline heterobifunctional bcl-x l degraders |
| CN118908940B (zh) * | 2024-10-11 | 2024-12-31 | 齐鲁理工学院 | 一种靶向抗凋亡Bcl-2的蛋白水解靶向嵌合体的制备和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005049593A2 (en) * | 2003-11-13 | 2005-06-02 | Abbott Laboratories | N-acylsulfonamide apoptosis promoters |
| CN109152933B (zh) * | 2016-04-21 | 2022-12-02 | 生物风险投资有限责任公司 | 诱导抗细胞凋亡bcl-2家族蛋白的降解的化合物及其用途 |
| KR20200108301A (ko) * | 2018-01-10 | 2020-09-17 | 리커리엄 아이피 홀딩스, 엘엘씨 | 벤즈아미드 화합물 |
| ES3041854T3 (en) * | 2018-01-22 | 2025-11-17 | Bioventures Llc | Bcl-2 proteins degraders for cancer treatment |
| US20230167105A1 (en) * | 2020-04-28 | 2023-06-01 | Recurium Ip Holdings, Llc | Bcl-2 protein inhibitors |
-
2020
- 2020-07-08 AU AU2020310147A patent/AU2020310147A1/en not_active Abandoned
- 2020-07-08 WO PCT/US2020/041175 patent/WO2021007307A1/en not_active Ceased
- 2020-07-08 EP EP20836203.8A patent/EP3972966A4/en not_active Withdrawn
- 2020-07-08 TW TW109123006A patent/TW202116758A/zh unknown
- 2020-07-08 JP JP2021576580A patent/JP2022540333A/ja not_active Ceased
- 2020-07-08 US US17/597,474 patent/US20220265834A1/en not_active Abandoned
- 2020-07-08 MX MX2022000310A patent/MX2022000310A/es unknown
- 2020-07-08 CN CN202080049518.8A patent/CN114144411A/zh active Pending
- 2020-07-08 CA CA3140085A patent/CA3140085A1/en active Pending
- 2020-07-08 AR ARP200101931A patent/AR119379A1/es not_active Application Discontinuation
- 2020-07-08 KR KR1020227002987A patent/KR20220034805A/ko not_active Withdrawn
-
2022
- 2022-01-04 IL IL289622A patent/IL289622A/en unknown
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