JP2019509286A5 - - Google Patents
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- JP2019509286A5 JP2019509286A5 JP2018546864A JP2018546864A JP2019509286A5 JP 2019509286 A5 JP2019509286 A5 JP 2019509286A5 JP 2018546864 A JP2018546864 A JP 2018546864A JP 2018546864 A JP2018546864 A JP 2018546864A JP 2019509286 A5 JP2019509286 A5 JP 2019509286A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- crystalline form
- form according
- chloro
- biphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2021177448A JP2022017433A (ja) | 2016-03-08 | 2021-10-29 | 結晶性(2s,4r)-5-(5’-クロロ-2’-フルオロ-[1,1’-ビフェニル]-4-イル)-2-(エトキシメチル)-4-(3-ヒドロキシイソオキサゾール-5-カルボキサミド)-2-メチルペンタン酸およびその使用 |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662305393P | 2016-03-08 | 2016-03-08 | |
US62/305,393 | 2016-03-08 | ||
US201662346336P | 2016-06-06 | 2016-06-06 | |
US62/346,336 | 2016-06-06 | ||
PCT/US2017/021172 WO2017156009A1 (en) | 2016-03-08 | 2017-03-07 | Crystalline(2s,4r)-5-(5'-chloro-2'-fluoro-[1,1'-biphenyl]-4-yl)-2-(ethoxymethyl)-4-(3-hydroxyisoxazole-5-carboxamido)-2-methylpentanoic acid and uses thereof |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2021177448A Division JP2022017433A (ja) | 2016-03-08 | 2021-10-29 | 結晶性(2s,4r)-5-(5’-クロロ-2’-フルオロ-[1,1’-ビフェニル]-4-イル)-2-(エトキシメチル)-4-(3-ヒドロキシイソオキサゾール-5-カルボキサミド)-2-メチルペンタン酸およびその使用 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2019509286A JP2019509286A (ja) | 2019-04-04 |
JP2019509286A5 true JP2019509286A5 (zh) | 2020-04-02 |
JP7306828B2 JP7306828B2 (ja) | 2023-07-11 |
Family
ID=58387911
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018546864A Active JP7306828B2 (ja) | 2016-03-08 | 2017-03-07 | 結晶性(2s,4r)-5-(5’-クロロ-2’-フルオロ-[1,1’-ビフェニル]-4-イル)-2-(エトキシメチル)-4-(3-ヒドロキシイソオキサゾール-5-カルボキサミド)-2-メチルペンタン酸およびその使用 |
JP2021177448A Pending JP2022017433A (ja) | 2016-03-08 | 2021-10-29 | 結晶性(2s,4r)-5-(5’-クロロ-2’-フルオロ-[1,1’-ビフェニル]-4-イル)-2-(エトキシメチル)-4-(3-ヒドロキシイソオキサゾール-5-カルボキサミド)-2-メチルペンタン酸およびその使用 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2021177448A Pending JP2022017433A (ja) | 2016-03-08 | 2021-10-29 | 結晶性(2s,4r)-5-(5’-クロロ-2’-フルオロ-[1,1’-ビフェニル]-4-イル)-2-(エトキシメチル)-4-(3-ヒドロキシイソオキサゾール-5-カルボキサミド)-2-メチルペンタン酸およびその使用 |
Country Status (28)
Country | Link |
---|---|
US (5) | US10100021B2 (zh) |
EP (1) | EP3408260B1 (zh) |
JP (2) | JP7306828B2 (zh) |
KR (2) | KR20220035991A (zh) |
CN (1) | CN108779084A (zh) |
AU (1) | AU2017229466C1 (zh) |
CA (1) | CA3015505C (zh) |
CL (1) | CL2018002539A1 (zh) |
CO (1) | CO2018010568A2 (zh) |
CY (1) | CY1124397T1 (zh) |
DK (1) | DK3408260T3 (zh) |
ES (1) | ES2880123T3 (zh) |
HR (1) | HRP20211169T1 (zh) |
HU (1) | HUE055546T2 (zh) |
IL (1) | IL261244B (zh) |
LT (1) | LT3408260T (zh) |
MX (1) | MX2018010727A (zh) |
PH (1) | PH12018501876A1 (zh) |
PL (1) | PL3408260T3 (zh) |
PT (1) | PT3408260T (zh) |
RS (1) | RS62172B1 (zh) |
RU (1) | RU2756223C2 (zh) |
SA (1) | SA518392325B1 (zh) |
SG (1) | SG11201807591VA (zh) |
SI (1) | SI3408260T1 (zh) |
TW (1) | TWI731943B (zh) |
WO (1) | WO2017156009A1 (zh) |
ZA (1) | ZA201805840B (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20220035991A (ko) | 2016-03-08 | 2022-03-22 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | (2s,4r)-5-(5'-클로로-2'-플루오로-[1,1'-비페닐]-4-일)-2-(에톡시메틸)-4-(3-히드록시이속사졸-5-카르복사미도)-2-메틸펜탄산 결정 및 그 용도 |
US20220395491A1 (en) * | 2019-09-20 | 2022-12-15 | Shenzhen Salubris Pharmaceuticals Co. Ltd | Uses of complex of angiotensin ii receptor antagonist metabolite and nep inhibitor in treating heart failure |
KR102485499B1 (ko) * | 2022-07-15 | 2023-01-09 | 오가노이드사이언스 주식회사 | 신장 질환의 치료 또는 예방용 조성물 |
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EP0225292A3 (en) | 1985-12-06 | 1988-11-30 | Ciba-Geigy Ag | Certain n-substituted butyramide derivatives |
US4929641B1 (en) | 1988-05-11 | 1994-08-30 | Schering Corp | Mercapto-acylamino acid antihypertensives |
KR880007441A (ko) | 1986-12-11 | 1988-08-27 | 알렌 제이.스피겔 | 스피로-치환된 글루타르아미드 이뇨제 |
FR2623498B1 (fr) | 1987-11-24 | 1990-04-06 | Bioprojet Soc Civ | Nouveaux composes enantiomeres derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques |
GB8820844D0 (en) | 1988-09-05 | 1988-10-05 | Pfizer Ltd | Therapeutic agents |
US5599951A (en) | 1989-09-15 | 1997-02-04 | Societe Civile Bioprojet | Amino acid derivatives, the process for their preparation and their applications to therapy |
US5155100A (en) | 1991-05-01 | 1992-10-13 | Ciba-Geigy Corporation | Phosphono/biaryl substituted dipeptide derivatives |
US5294632A (en) | 1991-05-01 | 1994-03-15 | Ciba-Geigy Corporation | Phosphono/biaryl substituted dipetide derivatives |
US5217996A (en) | 1992-01-22 | 1993-06-08 | Ciba-Geigy Corporation | Biaryl substituted 4-amino-butyric acid amides |
US5508272A (en) | 1993-06-15 | 1996-04-16 | Bristol-Myers Squibb Company | Compounds containing a fused bicycle ring and processes therefor |
DE19510566A1 (de) | 1995-03-23 | 1996-09-26 | Kali Chemie Pharma Gmbh | Benzazepin-, Benzoxazepin- und Benzothiazepin-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
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WO2006027680A1 (en) | 2004-09-10 | 2006-03-16 | Pfizer Limited | 3-(1-carbamoylcyclohexyl) propionic acid derivatives as inhibitors of neutral endopeptidase enzyme |
AR057882A1 (es) | 2005-11-09 | 2007-12-26 | Novartis Ag | Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra |
US20070204367A1 (en) | 2006-02-17 | 2007-08-30 | Stanislaw Flasinski | Chimeric regulatory sequences comprising introns for plant gene expression |
WO2007106708A2 (en) | 2006-03-10 | 2007-09-20 | Novartis Ag | Combinations of the angiotensin ii antagonist valsartan and the nep inhibitor daglutril |
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TWI448284B (zh) | 2007-04-24 | 2014-08-11 | Theravance Inc | 雙效抗高血壓劑 |
PE20091364A1 (es) | 2008-01-17 | 2009-10-13 | Novartis Ag | Proceso para la preparacion de inhibidores de nep |
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US8993631B2 (en) | 2010-11-16 | 2015-03-31 | Novartis Ag | Method of treating contrast-induced nephropathy |
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EP2714648B1 (en) | 2011-05-31 | 2017-08-16 | Theravance Biopharma R&D IP, LLC | Neprilysin inhibitors |
TWI560172B (en) | 2011-11-02 | 2016-12-01 | Theravance Biopharma R&D Ip Llc | Neprilysin inhibitors |
CN104350052B (zh) | 2012-05-31 | 2017-05-31 | 施万生物制药研发Ip有限责任公司 | 一氧化氮供体脑啡肽酶抑制剂 |
US8871792B2 (en) | 2012-06-08 | 2014-10-28 | Theravance Biopharma R&D Ip, Llc | Neprilysin inhibitors |
ME02698B (me) | 2012-06-08 | 2017-10-20 | Theravance Biopharma R&D Ip Llc | Inhibitori neprilizina |
CN104520277B (zh) * | 2012-08-08 | 2018-01-19 | 施万生物制药研发Ip有限责任公司 | 脑啡肽酶抑制剂 |
CA2915536C (en) * | 2013-06-19 | 2021-10-19 | F. Hoffmann-La Roche Ag | Indolin-2-one or pyrrolo-pyridin/pyrimidin-2-one derivatives |
JP2017507921A (ja) * | 2014-01-30 | 2017-03-23 | セラヴァンス バイオファーマ アール&ディー アイピー, エルエルシー | ネプリライシン阻害剤 |
KR20220035991A (ko) | 2016-03-08 | 2022-03-22 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | (2s,4r)-5-(5'-클로로-2'-플루오로-[1,1'-비페닐]-4-일)-2-(에톡시메틸)-4-(3-히드록시이속사졸-5-카르복사미도)-2-메틸펜탄산 결정 및 그 용도 |
-
2017
- 2017-03-07 KR KR1020227008251A patent/KR20220035991A/ko not_active IP Right Cessation
- 2017-03-07 AU AU2017229466A patent/AU2017229466C1/en active Active
- 2017-03-07 WO PCT/US2017/021172 patent/WO2017156009A1/en active Application Filing
- 2017-03-07 TW TW106107450A patent/TWI731943B/zh active
- 2017-03-07 SI SI201730845T patent/SI3408260T1/sl unknown
- 2017-03-07 ES ES17712605T patent/ES2880123T3/es active Active
- 2017-03-07 MX MX2018010727A patent/MX2018010727A/es active IP Right Grant
- 2017-03-07 RU RU2018135072A patent/RU2756223C2/ru active
- 2017-03-07 JP JP2018546864A patent/JP7306828B2/ja active Active
- 2017-03-07 PL PL17712605T patent/PL3408260T3/pl unknown
- 2017-03-07 CA CA3015505A patent/CA3015505C/en active Active
- 2017-03-07 SG SG11201807591VA patent/SG11201807591VA/en unknown
- 2017-03-07 KR KR1020187028757A patent/KR20180114225A/ko not_active IP Right Cessation
- 2017-03-07 DK DK17712605.9T patent/DK3408260T3/da active
- 2017-03-07 US US15/452,333 patent/US10100021B2/en active Active
- 2017-03-07 PT PT177126059T patent/PT3408260T/pt unknown
- 2017-03-07 RS RS20210963A patent/RS62172B1/sr unknown
- 2017-03-07 EP EP17712605.9A patent/EP3408260B1/en active Active
- 2017-03-07 CN CN201780016076.5A patent/CN108779084A/zh active Pending
- 2017-03-07 LT LTEP17712605.9T patent/LT3408260T/lt unknown
- 2017-03-07 HU HUE17712605A patent/HUE055546T2/hu unknown
-
2018
- 2018-08-20 IL IL261244A patent/IL261244B/en unknown
- 2018-08-30 ZA ZA2018/05840A patent/ZA201805840B/en unknown
- 2018-09-02 SA SA518392325A patent/SA518392325B1/ar unknown
- 2018-09-03 PH PH12018501876A patent/PH12018501876A1/en unknown
- 2018-09-05 CL CL2018002539A patent/CL2018002539A1/es unknown
- 2018-09-10 US US16/125,991 patent/US10472335B2/en active Active
- 2018-10-02 CO CONC2018/0010568A patent/CO2018010568A2/es unknown
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2019
- 2019-09-25 US US16/582,051 patent/US10752599B2/en active Active
-
2020
- 2020-07-14 US US16/928,206 patent/US11230536B2/en active Active
-
2021
- 2021-07-21 HR HRP20211169TT patent/HRP20211169T1/hr unknown
- 2021-07-30 CY CY20211100685T patent/CY1124397T1/el unknown
- 2021-10-29 JP JP2021177448A patent/JP2022017433A/ja active Pending
- 2021-12-14 US US17/550,564 patent/US11718591B2/en active Active
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