JP2019506134A5 - - Google Patents
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- Publication number
- JP2019506134A5 JP2019506134A5 JP2018519751A JP2018519751A JP2019506134A5 JP 2019506134 A5 JP2019506134 A5 JP 2019506134A5 JP 2018519751 A JP2018519751 A JP 2018519751A JP 2018519751 A JP2018519751 A JP 2018519751A JP 2019506134 A5 JP2019506134 A5 JP 2019506134A5
- Authority
- JP
- Japan
- Prior art keywords
- medium
- ali
- william
- spheroids
- complete
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 description 2
- 239000013589 supplement Substances 0.000 description 2
- HJCMDXDYPOUFDY-WHFBIAKZSA-N Ala-Gln Chemical compound C[C@H](N)C(=O)N[C@H](C(O)=O)CCC(N)=O HJCMDXDYPOUFDY-WHFBIAKZSA-N 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16185725.5 | 2016-08-25 | ||
| EP16185725.5A EP3287521B1 (en) | 2016-08-25 | 2016-08-25 | Cell culture |
| PCT/EP2017/070881 WO2018036910A1 (en) | 2016-08-25 | 2017-08-17 | Cell culture |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020205752A Division JP7097942B2 (ja) | 2016-08-25 | 2020-12-11 | 細胞培養 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019506134A JP2019506134A (ja) | 2019-03-07 |
| JP2019506134A5 true JP2019506134A5 (enExample) | 2020-07-16 |
| JP6810742B2 JP6810742B2 (ja) | 2021-01-06 |
Family
ID=56842661
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018519751A Active JP6810742B2 (ja) | 2016-08-25 | 2017-08-17 | 細胞培養 |
| JP2020205752A Expired - Fee Related JP7097942B2 (ja) | 2016-08-25 | 2020-12-11 | 細胞培養 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020205752A Expired - Fee Related JP7097942B2 (ja) | 2016-08-25 | 2020-12-11 | 細胞培養 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11041145B2 (enExample) |
| EP (2) | EP3940059A1 (enExample) |
| JP (2) | JP6810742B2 (enExample) |
| KR (1) | KR20180049000A (enExample) |
| CN (1) | CN108138135A (enExample) |
| PL (1) | PL3287521T3 (enExample) |
| RU (1) | RU2018111219A (enExample) |
| WO (1) | WO2018036910A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES3070913T3 (en) * | 2018-05-16 | 2026-06-18 | Inst Nat Sante Rech Med | Method of culturing proliferative hepatocytes |
| EP3927417A4 (en) * | 2019-02-19 | 2022-11-16 | Iontox LLC | METHOD FOR PREDICTING REPEATED-DOSE TOXICITY USING AN INTEGRATED ORGAN PLATFORM |
| CN113699202A (zh) * | 2020-05-21 | 2021-11-26 | 华子昂 | 一种用混合细胞与人工细胞培养巢制备胶原蛋白的方法 |
| WO2023282925A1 (en) * | 2021-07-08 | 2023-01-12 | Ourotech, Inc. | Treatment efficacy prediction systems and methods |
| CN120005810A (zh) * | 2025-04-18 | 2025-05-16 | 立沃生物科技（深圳）有限公司 | 肝祖细胞、应用及3d动态培养扩增方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2313377B (en) | 1996-05-20 | 1998-07-01 | Sumitomo Chemical Co | Kit for diagnosis of hepatitis C and alcoholic cirrhosis |
| GB9913979D0 (en) | 1999-06-17 | 1999-08-18 | Univ Wales Medicine | Spheroid preparation |
| US7351584B2 (en) | 2002-02-26 | 2008-04-01 | In Vitro Technologies, Inc. | Hepatocyte bioreactor system for long term culture of functional hepatocyte spheroids |
| EP1496066A4 (en) | 2002-03-25 | 2006-09-13 | Japan Science & Tech Agency | ANTIBODY RECOGNIZING PROLIFERATIVE HUMAN LIVER CELLS, PROLIFERATIVE HUMAN LIVER CELLS, AND FUNCTIONAL HUMAN LIVER CELLS |
| US7753192B2 (en) | 2005-12-23 | 2010-07-13 | The Coca-Cola Company | Apparatus and method for orienting spheroidal containers and packaging beverages in spheroidal containers |
| JP5217220B2 (ja) | 2007-04-12 | 2013-06-19 | 株式会社日立製作所 | 細胞分離装置 |
| CA2693481A1 (en) * | 2007-07-20 | 2009-01-29 | Cellartis Ab | A novel population of hepatocytes derived via definitive endoderm (de-hep) from human blastocysts derived stem cells |
| EP2334804B1 (en) | 2008-10-07 | 2013-12-04 | True North Therapeutics, Inc. | Co-culture compositions and methods |
| WO2010079602A1 (ja) | 2009-01-08 | 2010-07-15 | 株式会社日立製作所 | 動物肝細胞の培養方法 |
| GB201104511D0 (en) * | 2011-03-17 | 2011-05-04 | Univ Cardiff | Cell based screening assay |
| JP5812816B2 (ja) * | 2011-11-15 | 2015-11-17 | コバレントマテリアル株式会社 | 細胞培養担体及びその製造方法 |
| DE102011121317A1 (de) | 2011-12-16 | 2013-06-20 | Universitätsklinikum Hamburg-Eppendorf | Gerüstfreie Leberzellaggregate zur Verwendung bei der Transplantation |
| CN102559581B (zh) * | 2012-01-20 | 2014-09-10 | 四川大学华西医院 | 一种无血清肝细胞培养基 |
| WO2014050139A1 (ja) | 2012-09-27 | 2014-04-03 | 株式会社クラレ | サイトカインがチトクロムｐ４５０の代謝能に及ぼす影響を評価する方法および薬剤のスクリーニング方法 |
| US20140106356A1 (en) | 2012-10-12 | 2014-04-17 | National Taiwan University | Kit for drug metabolism determination and toxicity prediction |
| US9442105B2 (en) * | 2013-03-15 | 2016-09-13 | Organovo, Inc. | Engineered liver tissues, arrays thereof, and methods of making the same |
| US11447743B2 (en) | 2014-04-22 | 2022-09-20 | Nippon Shokubai Co., Ltd. | Cell culture substrate comprising fluorine-containing polymer on its surface |
| JP6681664B2 (ja) * | 2014-09-05 | 2020-04-15 | 株式会社日本触媒 | 含フッ素ポリイミドを含む酸素ガス透過性の細胞培養用基材、該基材を備えた細胞培養用容器、及び、該基材を用いた細胞培養方法 |
-
2016
- 2016-08-25 PL PL16185725T patent/PL3287521T3/pl unknown
- 2016-08-25 EP EP21180293.9A patent/EP3940059A1/en not_active Withdrawn
- 2016-08-25 EP EP16185725.5A patent/EP3287521B1/en active Active
-
2017
- 2017-08-17 WO PCT/EP2017/070881 patent/WO2018036910A1/en not_active Ceased
- 2017-08-17 CN CN201780003424.5A patent/CN108138135A/zh active Pending
- 2017-08-17 RU RU2018111219A patent/RU2018111219A/ru unknown
- 2017-08-17 US US15/757,415 patent/US11041145B2/en active Active
- 2017-08-17 KR KR1020187009401A patent/KR20180049000A/ko not_active Ceased
- 2017-08-17 JP JP2018519751A patent/JP6810742B2/ja active Active
-
2020
- 2020-12-11 JP JP2020205752A patent/JP7097942B2/ja not_active Expired - Fee Related
-
2021
- 2021-05-12 US US17/318,056 patent/US11981926B2/en active Active
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