GB201104511D0 - Cell based screening assay - Google Patents

Cell based screening assay

Info

Publication number
GB201104511D0
GB201104511D0 GBGB1104511.9A GB201104511A GB201104511D0 GB 201104511 D0 GB201104511 D0 GB 201104511D0 GB 201104511 A GB201104511 A GB 201104511A GB 201104511 D0 GB201104511 D0 GB 201104511D0
Authority
GB
United Kingdom
Prior art keywords
cell based
screening assay
based screening
test agent
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1104511.9A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University College Cardiff Consultants Ltd
Cardiff University
Original Assignee
University College Cardiff Consultants Ltd
Cardiff University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University College Cardiff Consultants Ltd, Cardiff University filed Critical University College Cardiff Consultants Ltd
Priority to GBGB1104511.9A priority Critical patent/GB201104511D0/en
Publication of GB201104511D0 publication Critical patent/GB201104511D0/en
Priority to PCT/GB2012/050463 priority patent/WO2012123712A1/en
Priority to GB1316076.7A priority patent/GB2502491A/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5067—Liver cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/14—Coculture with; Conditioned medium produced by hepatocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/27—Lung cells, respiratory tract cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/04—Screening or testing on artificial tissues

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The disclosure relates to a screening method for xenobiotic agents comprising contacting a co-culture with a test agent and determining the biological activity of the test agent on a lung epithelial cell cultured at an air-liquid interface.
GBGB1104511.9A 2011-03-17 2011-03-17 Cell based screening assay Ceased GB201104511D0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GBGB1104511.9A GB201104511D0 (en) 2011-03-17 2011-03-17 Cell based screening assay
PCT/GB2012/050463 WO2012123712A1 (en) 2011-03-17 2012-03-01 Cell-based screening assay
GB1316076.7A GB2502491A (en) 2011-03-17 2012-03-01 Cell-based screening assay

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1104511.9A GB201104511D0 (en) 2011-03-17 2011-03-17 Cell based screening assay

Publications (1)

Publication Number Publication Date
GB201104511D0 true GB201104511D0 (en) 2011-05-04

Family

ID=44012726

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1104511.9A Ceased GB201104511D0 (en) 2011-03-17 2011-03-17 Cell based screening assay
GB1316076.7A Withdrawn GB2502491A (en) 2011-03-17 2012-03-01 Cell-based screening assay

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1316076.7A Withdrawn GB2502491A (en) 2011-03-17 2012-03-01 Cell-based screening assay

Country Status (2)

Country Link
GB (2) GB201104511D0 (en)
WO (1) WO2012123712A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014062505A1 (en) * 2012-10-18 2014-04-24 The University Of Kansas Improved reliability of assays using a multi-divot platform and multi-source, multi-cell type clusters
WO2014151456A2 (en) * 2013-03-15 2014-09-25 The Jackson Laboratory Treatment of inflammatory diseases
PL3287521T3 (en) * 2016-08-25 2021-12-20 Philip Morris Products S.A. Cell culture
CN107121553B (en) * 2017-03-16 2019-08-27 国家烟草质量监督检验中心 A kind of liquid-vapor interface exposure system combines the method for high intension technology quantitative detection 1,3- butadiene cause DNA Damage

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3127198A (en) 1964-03-31 figure
US5989835A (en) 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
GB0030584D0 (en) 2000-12-15 2001-01-31 Univ Nottingham Hepatocyte Co-Culture
GB0716066D0 (en) 2007-08-17 2007-09-26 Univ Durham Stem cell derived neurotrophic factors
EP2334804B1 (en) 2008-10-07 2013-12-04 True North Therapeutics, Inc. Co-culture compositions and methods
CA2758208A1 (en) 2009-04-09 2010-10-14 Jordan Lancaster Cellular seeding and co-culture of a three dimensional fibroblast construct

Also Published As

Publication number Publication date
WO2012123712A1 (en) 2012-09-20
GB2502491A (en) 2013-11-27
GB201316076D0 (en) 2013-10-23

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)