JP2019505486A5 - - Google Patents
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- Publication number
- JP2019505486A5 JP2019505486A5 JP2018530079A JP2018530079A JP2019505486A5 JP 2019505486 A5 JP2019505486 A5 JP 2019505486A5 JP 2018530079 A JP2018530079 A JP 2018530079A JP 2018530079 A JP2018530079 A JP 2018530079A JP 2019505486 A5 JP2019505486 A5 JP 2019505486A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- osteoarthritis
- subject
- composition according
- cartilage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562264682P | 2015-12-08 | 2015-12-08 | |
| US62/264,682 | 2015-12-08 | ||
| PCT/US2016/065520 WO2017100400A2 (en) | 2015-12-08 | 2016-12-08 | Use of c-type natriuretic peptide variants to treat osteoarthritis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019505486A JP2019505486A (ja) | 2019-02-28 |
| JP2019505486A5 true JP2019505486A5 (enExample) | 2020-01-23 |
| JP7104625B2 JP7104625B2 (ja) | 2022-07-21 |
Family
ID=59013378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018530079A Active JP7104625B2 (ja) | 2015-12-08 | 2016-12-08 | 骨関節炎を処置するためのｃ型ナトリウム利尿ペプチド変異体の使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11202819B2 (enExample) |
| EP (2) | EP4019038A3 (enExample) |
| JP (1) | JP7104625B2 (enExample) |
| KR (1) | KR102941538B1 (enExample) |
| CN (1) | CN108697766A (enExample) |
| AU (2) | AU2016365751B2 (enExample) |
| CA (1) | CA3007315A1 (enExample) |
| DK (1) | DK3386531T3 (enExample) |
| ES (1) | ES2901769T3 (enExample) |
| HR (1) | HRP20211908T1 (enExample) |
| HU (1) | HUE057083T2 (enExample) |
| IL (1) | IL259690B2 (enExample) |
| MX (1) | MX2018006986A (enExample) |
| PL (1) | PL3386531T3 (enExample) |
| PT (1) | PT3386531T (enExample) |
| RU (1) | RU2759679C2 (enExample) |
| WO (1) | WO2017100400A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017205693B2 (en) | 2016-01-08 | 2022-03-31 | Ascendis Pharma Growth Disorders A/S | Controlled-release CNP agonists with low initial NPR-B activity |
| JP6968802B2 (ja) | 2016-01-08 | 2021-11-17 | アセンディス ファーマ グロース ディスオーダーズ エー／エス | 環部分にキャリア結合を有するｃｎｐプロドラッグ |
| CA3008015A1 (en) | 2016-01-08 | 2017-07-13 | Ascendis Pharma Growth Disorders A/S | Controlled-release c-type natriuretic peptide agonists with increased neutral endopeptidase stability |
| EP4710947A3 (en) | 2016-01-08 | 2026-06-17 | Ascendis Pharma Growth Disorders A/S | Controlled-release cnp agonists with reduced side-effects |
| KR102518217B1 (ko) | 2016-01-08 | 2023-04-04 | 아센디스 파마 그로우쓰 디스오더스 에이/에스 | 낮은 npr-c 결합을 갖는 제어 방출성 cnp 작용제 |
| US10835578B2 (en) | 2016-01-08 | 2020-11-17 | Ascendis Pharma Growth Disorders A/S | CNP prodrugs with large carrier moieties |
| RU2768747C2 (ru) | 2016-09-29 | 2022-03-24 | Асцендис Фарма Гроус Дизордерс А/С | Комбинаторная терапия с агонистами cnp контролируемого высвобождения |
| CN112752556A (zh) * | 2018-04-27 | 2021-05-04 | 雷米生物科学公司 | 新的医疗装置、递送运载体及其制造 |
| EP3923906A1 (en) * | 2019-02-11 | 2021-12-22 | Ascendis Pharma Growth Disorders A/S | Dry pharmaceutical formulations of cnp conjugates |
| CN116635027A (zh) * | 2020-11-25 | 2023-08-22 | 普罗林科斯有限责任公司 | C-利钠肽的延长释放水凝胶偶联物 |
| WO2022240936A1 (en) * | 2021-05-11 | 2022-11-17 | Texas Tech University System | Targeted selenium conjugates as countermeasures for pathogenic viruses and cells |
| CA3242257A1 (en) * | 2021-12-07 | 2023-06-15 | Biomarin Pharmaceutical Inc. | C-type natriuretic peptide therapy of bone-related disorders |
| WO2024104922A1 (en) | 2022-11-14 | 2024-05-23 | Ascendis Pharma Growth Disorders A/S | Method of improving skeletal muscle function |
| KR102866559B1 (ko) | 2022-11-02 | 2025-10-02 | 노보 노르디스크 에이/에스 | Cnp 화합물 |
| KR20250162619A (ko) | 2023-03-20 | 2025-11-18 | 아센디스 파마 그로우쓰 디스오더스 에이/에스 | 연골무형성증을 가진 인간 대상에서의 흉요추 변형의 치료 방법 |
| KR20250098109A (ko) * | 2023-12-21 | 2025-07-01 | 주식회사 펩트론 | 나트륨이뇨 펩타이드 유사체 및 이의 용도 |
| CN117801123B (zh) * | 2024-02-29 | 2024-05-03 | 天津凯莱英生物科技有限公司 | 沃索利肽可溶性中间体、中间体制备方法及沃索利肽的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5252714A (en) | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
| JP2809533B2 (ja) | 1991-01-31 | 1998-10-08 | 壽之 松尾 | Ｃｎｐ類似体ペプチド |
| US5824784A (en) | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
| IL142118A0 (en) | 2001-03-20 | 2002-03-10 | Prochon Biotech Ltd | Method and composition for treatment of skeletal dysplasias |
| KR20070007842A (ko) * | 2004-03-31 | 2007-01-16 | 카즈와 나카오 | 신장증가용 조성물 |
| ES2465141T3 (es) * | 2004-03-31 | 2014-06-05 | Kazuwa Nakao | Remedio o medicamento preventivo para la artritis |
| AR069409A1 (es) | 2007-11-21 | 2010-01-20 | Biomarin Pharm Inc | Variantes de peptidos natriureticos de tipo c |
| EP2432489B1 (en) | 2009-05-20 | 2016-10-05 | BioMarin Pharmaceutical Inc. | Variants of c-type natriuretic peptide |
| JP6055779B2 (ja) * | 2010-12-27 | 2016-12-27 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | ナトリウム利尿ペプチドを含む組成物およびその使用方法 |
-
2016
- 2016-12-08 DK DK16852866.9T patent/DK3386531T3/da active
- 2016-12-08 EP EP21202207.3A patent/EP4019038A3/en active Pending
- 2016-12-08 AU AU2016365751A patent/AU2016365751B2/en active Active
- 2016-12-08 EP EP16852866.9A patent/EP3386531B1/en active Active
- 2016-12-08 CA CA3007315A patent/CA3007315A1/en active Pending
- 2016-12-08 KR KR1020187019166A patent/KR102941538B1/ko active Active
- 2016-12-08 HU HUE16852866A patent/HUE057083T2/hu unknown
- 2016-12-08 MX MX2018006986A patent/MX2018006986A/es unknown
- 2016-12-08 RU RU2018124600A patent/RU2759679C2/ru active
- 2016-12-08 HR HRP20211908TT patent/HRP20211908T1/hr unknown
- 2016-12-08 ES ES16852866T patent/ES2901769T3/es active Active
- 2016-12-08 WO PCT/US2016/065520 patent/WO2017100400A2/en not_active Ceased
- 2016-12-08 CN CN201680081329.2A patent/CN108697766A/zh active Pending
- 2016-12-08 PT PT168528669T patent/PT3386531T/pt unknown
- 2016-12-08 US US15/779,049 patent/US11202819B2/en active Active
- 2016-12-08 PL PL16852866T patent/PL3386531T3/pl unknown
- 2016-12-08 JP JP2018530079A patent/JP7104625B2/ja active Active
-
2018
- 2018-05-29 IL IL259690A patent/IL259690B2/en unknown
-
2021
- 2021-12-03 US US17/541,992 patent/US12214015B2/en active Active
-
2024
- 2024-03-21 AU AU2024201852A patent/AU2024201852A1/en active Pending
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