JP2019503703A5 - - Google Patents

Download PDF

Info

Publication number
JP2019503703A5
JP2019503703A5 JP2018540792A JP2018540792A JP2019503703A5 JP 2019503703 A5 JP2019503703 A5 JP 2019503703A5 JP 2018540792 A JP2018540792 A JP 2018540792A JP 2018540792 A JP2018540792 A JP 2018540792A JP 2019503703 A5 JP2019503703 A5 JP 2019503703A5
Authority
JP
Japan
Prior art keywords
signaling
population
activators
stem cells
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018540792A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019503703A (ja
JP7523885B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/016723 external-priority patent/WO2017136834A1/en
Publication of JP2019503703A publication Critical patent/JP2019503703A/ja
Publication of JP2019503703A5 publication Critical patent/JP2019503703A5/ja
Priority to JP2022065090A priority Critical patent/JP2022088676A/ja
Application granted granted Critical
Publication of JP7523885B2 publication Critical patent/JP7523885B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018540792A 2016-02-05 2017-02-06 幹細胞由来外胚葉系統前駆体を分化する方法 Active JP7523885B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022065090A JP2022088676A (ja) 2016-02-05 2022-04-11 幹細胞由来外胚葉系統前駆体を分化する方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662292014P 2016-02-05 2016-02-05
US62/292,014 2016-02-05
US201662299361P 2016-02-24 2016-02-24
US62/299,361 2016-02-24
US62/350,032 2016-06-14
US201662350032P 2016-06-15 2016-06-15
PCT/US2017/016723 WO2017136834A1 (en) 2016-02-05 2017-02-06 Methods of differentiating stem cell-derived ectodermal lineage precursors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022065090A Division JP2022088676A (ja) 2016-02-05 2022-04-11 幹細胞由来外胚葉系統前駆体を分化する方法

Publications (3)

Publication Number Publication Date
JP2019503703A JP2019503703A (ja) 2019-02-14
JP2019503703A5 true JP2019503703A5 (https=) 2020-02-27
JP7523885B2 JP7523885B2 (ja) 2024-07-29

Family

ID=59500066

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018540792A Active JP7523885B2 (ja) 2016-02-05 2017-02-06 幹細胞由来外胚葉系統前駆体を分化する方法
JP2022065090A Pending JP2022088676A (ja) 2016-02-05 2022-04-11 幹細胞由来外胚葉系統前駆体を分化する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022065090A Pending JP2022088676A (ja) 2016-02-05 2022-04-11 幹細胞由来外胚葉系統前駆体を分化する方法

Country Status (8)

Country Link
US (3) US11326148B2 (https=)
EP (1) EP3411048A4 (https=)
JP (2) JP7523885B2 (https=)
KR (1) KR20180105236A (https=)
AU (1) AU2017214749B2 (https=)
CA (1) CA3013623A1 (https=)
IL (1) IL260979B2 (https=)
WO (1) WO2017136834A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180105236A (ko) 2016-02-05 2018-09-27 메모리얼 슬로안-케터링 캔서 센터 줄기 세포-유래 외배엽 계통 전구체의 분화 방법
WO2018024186A1 (zh) * 2016-08-02 2018-02-08 江苏恒瑞医药股份有限公司 一种人胰岛素或其类似物的酰化衍生物
CA3075036A1 (en) * 2017-09-07 2019-03-14 Memorial Sloan-Kettering Cancer Center Methods of differentiating stem cell-derived ectodermal lineage precursors
WO2019094873A1 (en) * 2017-11-10 2019-05-16 Memorial Sloan-Kettering Cancer Center Derivation of somatotrophs from stem cells and uses thereof
IT201800009133A1 (it) * 2018-10-03 2020-04-03 Università Cattolica del Sacro Cuore Identificazione di biomarcatori molecolari predittivi di risposta al trattamento radiochemoterapico nel carcinoma della cervice
KR102451074B1 (ko) * 2019-01-11 2022-10-05 차의과학대학교 산학협력단 Ｔｇｆ-베타 ⅰ 수용체의 저해제 및 ｂｍｐ 저해제를 포함하는 줄기 세포의 신경능선세포로의 분화용 조성물, 키트, 및 이를 이용한 방법
KR20200087541A (ko) * 2019-01-11 2020-07-21 차의과학대학교 산학협력단 Ｔｇｆ-베타 ⅰ 수용체의 저해제 및 ｂｍｐ 저해제를 포함하는 줄기 세포의 신경능선세포로의 분화용 조성물, 키트, 및 이를 이용한 방법
WO2025085899A1 (en) * 2023-10-19 2025-04-24 The Research Foundation For The State University Of New York Production of salivary gland epithelial progenitors and salivary gland cell organoids for regenerative medicine and drug testing purposes

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5649786B2 (ja) 2006-03-07 2015-01-07 ギータ シュロフ ヒト胚性幹細胞およびそれらの誘導体を含む組成物、使用方法、ならびに調製方法
WO2008008266A2 (en) 2006-07-07 2008-01-17 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Biohybrid elastomeric scaffolds and methods of use thereof
WO2010096496A2 (en) 2009-02-17 2010-08-26 Memorial Sloan-Kettering Cancer Center Methods of neural conversion of human embryonic stem cells
WO2011019092A1 (en) 2009-08-12 2011-02-17 Kyoto University Method for inducing differentiation of pluripotent stem cells into neural precursor cells
DK3578988T3 (da) 2010-05-25 2025-02-24 Memorial Sloan Kettering Cancer Center Fremgangsmåde til nociceptordifferentiering af humane embryonale stamceller og anvendelse heraf
US20110296542A1 (en) 2010-05-28 2011-12-01 Kevin Ka-Wang Wang Exogenous matrix-supported topical application of stem cells to organ surface
WO2012091978A2 (en) 2010-12-31 2012-07-05 University Of Georgia Research Foundation, Inc. Differentiation of human pluripotent stem cells to multipotent neural crest cells
EP2667881A4 (en) * 2011-01-24 2015-04-22 Univ Leland Stanford Junior METHOD FOR IN VITRO GENERATION OF INTERNAL CELLS
EP3693455A1 (en) * 2011-11-04 2020-08-12 Memorial Sloan-Kettering Cancer Center Midbrain dopamine (da) neurons for engraftment
WO2013166488A1 (en) * 2012-05-04 2013-11-07 Indiana University Research & Technology Corporation Methods for generating the inner ear and other cranial placode-derived tissues using pluripotent stem cells
WO2013188744A1 (en) 2012-06-15 2013-12-19 Baylor College Of Medicine Perineurium derived adult stem cells and methods of use
US10160950B2 (en) * 2013-03-01 2018-12-25 Wisconsin Alumni Research Foundation Methods of maintaining, expanding and differentiating neuronal subtype specific progenitors
EP3498824A1 (en) 2013-04-26 2019-06-19 Memorial Sloan-Kettering Cancer Center Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells
AU2014352773B2 (en) 2013-11-21 2021-04-29 Memorial Sloan-Kettering Cancer Center Specification of functional cranial placode derivatives from human pluripotent stem cells
JP6304818B2 (ja) 2014-04-21 2018-04-04 花王株式会社 皮膚由来多能性前駆細胞の作製方法
JP6598185B2 (ja) 2014-11-07 2019-10-30 国立大学法人京都大学 軟骨過形成疾患の予防および治療剤ならびにそのスクリーニング方法
WO2016104574A1 (ja) 2014-12-24 2016-06-30 国立大学法人京都大学 異所性骨化の予防・治療剤及びそのスクリーニング方法
AU2016270793B2 (en) * 2015-06-01 2022-06-09 Memorial Sloan-Kettering Cancer Center Methods of in vitro differentiation of midbrain dopamine (MDA) neurons
US11186821B2 (en) 2015-06-02 2021-11-30 National Institute Of Advanced Industrial Science And Technology Method for inducing differentiation of neural crest cells into neurons of the autonomic nervous system
SG11201803061UA (en) * 2015-10-21 2018-05-30 Univ Indiana Res & Tech Corp Methods of generating human inner ear sensory epithelia and sensory neurons
EP3414322A4 (en) * 2015-12-23 2020-03-04 Memorial Sloan-Kettering Cancer Center CELL THERAPY AND DRUG DISCOVERY BASED ON CELL LINES DERIVED FROM HUMAN ENTERAL NEURAL CREST DERIVED FROM PLURIPOTENT STEM CELLS
EP3448985A4 (en) * 2016-01-27 2019-08-21 Memorial Sloan-Kettering Cancer Center DIFFERENTIATION OF CORTIC NEURONS FROM HUMAN PLURIPOTENTIAL STEM CELLS
KR20180105236A (ko) 2016-02-05 2018-09-27 메모리얼 슬로안-케터링 캔서 센터 줄기 세포-유래 외배엽 계통 전구체의 분화 방법

Similar Documents

Publication Publication Date Title
JP2019503703A5 (https=)
AU2021266324B2 (en) In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (pec) and endocrine cells
AU2021218116B2 (en) Midbrain dopamine (DA) neurons for engraftment
Li et al. Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors
Reichman et al. From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium
Gorris et al. Pluripotent stem cell‐derived radial glia‐like cells as stable intermediate for efficient generation of human oligodendrocytes
JP6636427B2 (ja) 小分子を用いるヒト多能性幹細胞からの内分泌始原細胞の作製
Mizuseki et al. Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells
Lang et al. Differentiation of embryonic stem cells to a neural fate: a route to re‐building the nervous system?
CN109415685B (zh) 用于体外制造胃底组织的方法和与其相关的组合物
Lee et al. Enhancement of osteogenic and chondrogenic differentiation of human embryonic stem cells by mesodermal lineage induction with BMP-4 and FGF2 treatment
Reynolds et al. Human embryonic stem cell applications for retinal degenerations
JP2019503679A5 (https=)
JP2018027099A5 (https=)
IL320440A (en) Methods of in vitro differentiation of midbrain dopamine (mda) neurons
BR112015022770A8 (pt) meio e sistema de cultivo da célula livre de xenógeno, livre de albumina, forma concentrada, métodos de diferenciação de células-tronco pluripotentes humanas, para a produção de mesenquimoangioblastos e sistema definido de cultivo da célula para diferenciação hematoendotelial das células- tronco pluripotentes humanas
JP2023520466A5 (https=)
JP2019506901A5 (https=)
AU2017214749B2 (en) Methods of differentiating stem cell-derived ectodermal lineage precursors
Ochiai et al. BMP4 and FGF strongly induce differentiation of mouse ES cells into oral ectoderm
JP2018502576A5 (https=)
WO2015147047A1 (ja) 多能性幹細胞培養用培地
WO2019144605A1 (zh) 一种高效的hPSCs向MSCs分化的方法
Shiraki et al. Differentiation and characterization of embryonic stem cells into three germ layers
Li et al. Combined activin A/LiCl/Noggin treatment improves production of mouse embryonic stem cell‐derived definitive endoderm cells