JP2019506901A5 - - Google Patents
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- JP2019506901A5 JP2019506901A5 JP2018559165A JP2018559165A JP2019506901A5 JP 2019506901 A5 JP2019506901 A5 JP 2019506901A5 JP 2018559165 A JP2018559165 A JP 2018559165A JP 2018559165 A JP2018559165 A JP 2018559165A JP 2019506901 A5 JP2019506901 A5 JP 2019506901A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitors
- signaling
- cell population
- tgfβ
- activin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022181861A JP2023011944A (ja) | 2016-01-27 | 2022-11-14 | ヒト人工多能性幹細胞からの皮質ニューロンの分化 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662287821P | 2016-01-27 | 2016-01-27 | |
| US62/287,821 | 2016-01-27 | ||
| US201762449488P | 2017-01-23 | 2017-01-23 | |
| US62/449,488 | 2017-01-23 | ||
| PCT/US2017/015480 WO2017132596A1 (en) | 2016-01-27 | 2017-01-27 | Differentiation of cortical neurons from human pluripotent stem cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022181861A Division JP2023011944A (ja) | 2016-01-27 | 2022-11-14 | ヒト人工多能性幹細胞からの皮質ニューロンの分化 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019506901A JP2019506901A (ja) | 2019-03-14 |
| JP2019506901A5 true JP2019506901A5 (https=) | 2020-03-12 |
| JP7196376B2 JP7196376B2 (ja) | 2022-12-27 |
Family
ID=59398774
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018559165A Active JP7196376B2 (ja) | 2016-01-27 | 2017-01-27 | ヒト人工多能性幹細胞からの皮質ニューロンの分化 |
| JP2022181861A Pending JP2023011944A (ja) | 2016-01-27 | 2022-11-14 | ヒト人工多能性幹細胞からの皮質ニューロンの分化 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022181861A Pending JP2023011944A (ja) | 2016-01-27 | 2022-11-14 | ヒト人工多能性幹細胞からの皮質ニューロンの分化 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20180346875A1 (https=) |
| EP (1) | EP3448985A4 (https=) |
| JP (2) | JP7196376B2 (https=) |
| KR (1) | KR20190035600A (https=) |
| AU (1) | AU2017211858B2 (https=) |
| CA (1) | CA3013054A1 (https=) |
| IL (1) | IL260824A (https=) |
| WO (1) | WO2017132596A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20180105236A (ko) * | 2016-02-05 | 2018-09-27 | 메모리얼 슬로안-케터링 캔서 센터 | 줄기 세포-유래 외배엽 계통 전구체의 분화 방법 |
| WO2017173064A1 (en) | 2016-03-30 | 2017-10-05 | Asterias Biotherapeutics, Inc. | Oligodendrocyte progenitor cell compositions |
| CN108359638B (zh) * | 2018-04-04 | 2020-02-14 | 浙江霍德生物工程有限公司 | 功能大脑皮层细胞的诱导分化方法 |
| US12365872B2 (en) | 2018-09-19 | 2025-07-22 | Lineage Cell Therapeutics, Inc. | Methods for differentiating pluripotent stem cells in dynamic suspension culture |
| KR20260020476A (ko) * | 2019-01-23 | 2026-02-11 | 아스테리아스 바이오세라퓨틱스, 인크. | 인간 만능 줄기 세포로부터의 배측-유래된 희소돌기아교세포 전구 세포 |
| AU2020263484B2 (en) * | 2019-04-24 | 2026-04-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nociceptor differentiation from human pluripotent stem cells |
| JP7810357B2 (ja) * | 2019-07-25 | 2026-02-03 | ザ スクリプス リサーチ インスティテュート | ドーパミン作動性ニューロン及び前駆細胞を特定する方法 |
| WO2022020798A1 (en) * | 2020-07-24 | 2022-01-27 | The Scripps Research Institute | Methods of differentiating neurons and identification of disease phenotypes thereof |
| CN112553160B (zh) * | 2020-12-25 | 2023-10-27 | 武汉睿健医药科技有限公司 | 一种化学诱导皮质神经元的方法及培养基 |
| CA3204035A1 (en) * | 2021-01-07 | 2022-07-14 | Lorenz Studer | Methods of generating cortical excitatory neurons |
| US12406510B2 (en) * | 2021-03-26 | 2025-09-02 | Howard University | Method for the detection, segmentation and morphological mapping on neural cell images of the whole brain |
| CN115572712A (zh) * | 2021-06-21 | 2023-01-06 | 香港再生医学有限公司 | 促使iPSC分化为中枢神经元细胞的方法及培养基和系统 |
| MX2024004934A (es) * | 2021-10-29 | 2024-09-10 | Duke Univeristy | Composiciones y sistemas para la edicion de celulas programables por arn y metodos para elaborar y usar los mismos. |
| WO2023104792A1 (en) | 2021-12-07 | 2023-06-15 | Vib Vzw | Enhancers of neuronal maturation |
| CN118064356A (zh) * | 2022-11-22 | 2024-05-24 | 浙江霍德生物工程有限公司 | 前脑神经前体细胞在治疗与前脑神经细胞的死亡和/或功能不全相关的疾病中的应用 |
| US12565639B2 (en) | 2023-06-13 | 2026-03-03 | Aspen Neuroscience, Inc. | Methods for differentiating dopaminergic neurons from stem cells |
| CN116970566B (zh) * | 2023-09-22 | 2024-01-09 | 北京大学口腔医学院 | 诱导间充质干细胞神经分化的方法、神经干细胞及用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2009148170A1 (ja) | 2008-06-06 | 2011-11-04 | 独立行政法人理化学研究所 | 幹細胞の培養方法 |
| WO2010144696A1 (en) * | 2009-06-11 | 2010-12-16 | Burnham Institute For Medical Research | Directed differentiation of stem cells |
| DK3578988T3 (da) * | 2010-05-25 | 2025-02-24 | Memorial Sloan Kettering Cancer Center | Fremgangsmåde til nociceptordifferentiering af humane embryonale stamceller og anvendelse heraf |
| US20150329821A1 (en) * | 2012-10-19 | 2015-11-19 | Agency For Science, Technology And Research | Methods of differentiating stem cells into one or more cell lineages |
| EP2951290B1 (en) | 2013-02-01 | 2017-11-29 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs) |
| EP3498824A1 (en) * | 2013-04-26 | 2019-06-19 | Memorial Sloan-Kettering Cancer Center | Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells |
| ES2939807T3 (es) * | 2014-03-21 | 2023-04-27 | Fujifilm Cellular Dynamics Inc | Producción de neuronas dopaminérgicas del mesencéfalo y métodos para su utilización |
-
2017
- 2017-01-27 EP EP17745034.3A patent/EP3448985A4/en not_active Withdrawn
- 2017-01-27 CA CA3013054A patent/CA3013054A1/en active Pending
- 2017-01-27 JP JP2018559165A patent/JP7196376B2/ja active Active
- 2017-01-27 KR KR1020187024543A patent/KR20190035600A/ko not_active Withdrawn
- 2017-01-27 AU AU2017211858A patent/AU2017211858B2/en not_active Expired - Fee Related
- 2017-01-27 WO PCT/US2017/015480 patent/WO2017132596A1/en not_active Ceased
-
2018
- 2018-07-27 US US16/047,393 patent/US20180346875A1/en not_active Abandoned
- 2018-07-29 IL IL260824A patent/IL260824A/en unknown
-
2022
- 2022-11-14 JP JP2022181861A patent/JP2023011944A/ja active Pending
-
2023
- 2023-05-30 US US18/325,690 patent/US20230323294A1/en not_active Abandoned
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