JP2019501631A5 - - Google Patents

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Publication number
JP2019501631A5
JP2019501631A5 JP2018521289A JP2018521289A JP2019501631A5 JP 2019501631 A5 JP2019501631 A5 JP 2019501631A5 JP 2018521289 A JP2018521289 A JP 2018521289A JP 2018521289 A JP2018521289 A JP 2018521289A JP 2019501631 A5 JP2019501631 A5 JP 2019501631A5
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JP
Japan
Prior art keywords
seq
receptor agonist
agonist protein
gitr receptor
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018521289A
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English (en)
Japanese (ja)
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JP2019501631A (ja
JP6959229B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2016/075552 external-priority patent/WO2017068185A1/en
Publication of JP2019501631A publication Critical patent/JP2019501631A/ja
Publication of JP2019501631A5 publication Critical patent/JP2019501631A5/ja
Application granted granted Critical
Publication of JP6959229B2 publication Critical patent/JP6959229B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2018521289A 2015-10-23 2016-10-24 一本鎖gitr受容体アゴニストタンパク質 Expired - Fee Related JP6959229B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562245815P 2015-10-23 2015-10-23
US62/245,815 2015-10-23
PCT/EP2016/075552 WO2017068185A1 (en) 2015-10-23 2016-10-24 Single-chain gitr-receptor agonist proteins

Publications (3)

Publication Number Publication Date
JP2019501631A JP2019501631A (ja) 2019-01-24
JP2019501631A5 true JP2019501631A5 (https=) 2019-12-05
JP6959229B2 JP6959229B2 (ja) 2021-11-02

Family

ID=57241058

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018521289A Expired - Fee Related JP6959229B2 (ja) 2015-10-23 2016-10-24 一本鎖gitr受容体アゴニストタンパク質

Country Status (7)

Country Link
US (2) US10533043B2 (https=)
EP (1) EP3365363A1 (https=)
JP (1) JP6959229B2 (https=)
CN (1) CN108473549A (https=)
AU (1) AU2016341402B2 (https=)
CA (1) CA3002741A1 (https=)
WO (1) WO2017068185A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA41460A (fr) 2015-02-03 2017-12-12 Oncomed Pharm Inc Agents de liaison à la tnfrsf et leurs utilisations
CN110869392A (zh) 2017-05-16 2020-03-06 百时美施贵宝公司 用抗gitr激动性抗体治疗癌症
EP4149964A2 (en) 2020-05-15 2023-03-22 Apogenix AG Multi-specific immune modulators
WO2023088876A1 (en) 2021-11-16 2023-05-25 Apogenix Ag Multi-specific immune modulators

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE339507T1 (de) 1998-06-15 2006-10-15 Gtc Biotherapeutics Inc Erythropoietin-analog-menschliches serum-albumin fusionsprotein
EP1107989B1 (en) 1998-08-25 2010-03-31 Merck Patent GmbH Expression and export of angiostatin and endostatin as immunofusins
AU7645700A (en) 1999-10-07 2001-05-10 Maxygen Aps Single-chain antagonist polypeptides
DE19963859A1 (de) 1999-12-30 2001-07-12 Apotech Res & Dev Ltd Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen
CA2314199A1 (en) 2000-07-21 2002-01-21 Robert Simoneau C-chip
DE10122140A1 (de) * 2001-05-08 2002-11-28 Apotech Res & Dev Ltd Rekombinante Fusionsproteine und deren Trimere
DE102004014983A1 (de) * 2004-03-26 2005-10-20 Univ Stuttgart Rekombinante Polypeptide der Mitglieder der TNF Ligandenfamilie und deren Verwendung
EP1746161A1 (en) * 2005-07-20 2007-01-24 Cytheris Glycosylated IL-7, preparation and uses
PL2005185T3 (pl) * 2006-03-22 2011-05-31 Viral Logic Systems Tech Corp Sposoby identyfikowania celów polipeptydowych
JP5283104B2 (ja) * 2007-01-10 2013-09-04 独立行政法人理化学研究所 アセチル化及び脱アセチル化の蛍光可視化検出方法
MX2009008754A (es) * 2007-02-14 2009-11-02 Glaxo Group Ltd Anticuerpos novedosos contra igf-1r.
EP2176288B1 (en) 2007-07-10 2015-11-04 Apogenix GmbH Tnf superfamily collectin fusion proteins
CA2694055A1 (en) * 2007-08-01 2009-02-05 Glaxo Group Limited Novel antibodies
PE20100092A1 (es) 2008-06-03 2010-03-12 Abbott Lab Inmunoglobulina con dominio variable dual y usos de la misma
DK2604693T3 (en) 2008-07-21 2016-05-30 Apogenix Gmbh Single-chain TNFSF molecules
JP5844158B2 (ja) 2009-01-09 2016-01-13 アポゲニクス ゲゼルシャフト ミット ベシュレンクテル ハフツングApogenix GmbH 三量体形成融合タンパク質
US8637637B2 (en) * 2010-01-12 2014-01-28 Bill Nai-Chau Sun Fc fusion proteins of human growth hormone
CN102250250A (zh) * 2011-07-09 2011-11-23 浙江大学 一种人鼠嵌合型抗人CD19抗体Hm2E8b及用途
US9764038B2 (en) * 2011-12-23 2017-09-19 Innate Pharma Enzymatic conjugation of antibodies
NO2776305T3 (https=) * 2014-04-23 2018-01-27
JP2014218510A (ja) * 2014-08-11 2014-11-20 アポゲニクスゲゼルシャフト ミット ベシュレンクテルハフツングApogenix GmbH 三量体形成融合タンパク質

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