JP2019500850A5 - - Google Patents

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Publication number
JP2019500850A5
JP2019500850A5 JP2018521279A JP2018521279A JP2019500850A5 JP 2019500850 A5 JP2019500850 A5 JP 2019500850A5 JP 2018521279 A JP2018521279 A JP 2018521279A JP 2018521279 A JP2018521279 A JP 2018521279A JP 2019500850 A5 JP2019500850 A5 JP 2019500850A5
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JP
Japan
Prior art keywords
seq
receptor agonist
cd137l
agonist protein
domain
Prior art date
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Application number
JP2018521279A
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English (en)
Japanese (ja)
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JP7033062B2 (ja
JP2019500850A (ja
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Priority claimed from PCT/EP2016/075543 external-priority patent/WO2017068183A1/en
Publication of JP2019500850A publication Critical patent/JP2019500850A/ja
Publication of JP2019500850A5 publication Critical patent/JP2019500850A5/ja
Application granted granted Critical
Publication of JP7033062B2 publication Critical patent/JP7033062B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2018521279A 2015-10-23 2016-10-24 一本鎖ｃｄ１３７受容体アゴニストタンパク質 Expired - Fee Related JP7033062B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562245838P 2015-10-23 2015-10-23
US62/245,838 2015-10-23
PCT/EP2016/075543 WO2017068183A1 (en) 2015-10-23 2016-10-24 Single-chain cd137-receptor agonist proteins

Publications (3)

Publication Number Publication Date
JP2019500850A JP2019500850A (ja) 2019-01-17
JP2019500850A5 true JP2019500850A5 (https=) 2019-12-05
JP7033062B2 JP7033062B2 (ja) 2022-03-09

Family

ID=57208274

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018521279A Expired - Fee Related JP7033062B2 (ja) 2015-10-23 2016-10-24 一本鎖ｃｄ１３７受容体アゴニストタンパク質

Country Status (7)

Country Link
US (2) US10870688B2 (https=)
EP (1) EP3365448A1 (https=)
JP (1) JP7033062B2 (https=)
CN (1) CN108368511B (https=)
AU (2) AU2016341400B2 (https=)
CA (1) CA3002588C (https=)
WO (1) WO2017068183A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX395639B (es) 2017-01-20 2025-03-25 Heidelberg Pharma Res Gmbh Composiciones y métodos para el agotamiento de células cd137+.
WO2019109238A1 (en) 2017-12-05 2019-06-13 Lyvgen Biopharma Co., Ltd. Anti-cd137 antibodies and uses thereof
WO2020069382A1 (en) * 2018-09-28 2020-04-02 Lyvgen Biopharma Co., Ltd. Anti-cd137 binding molecules having engineered fc domains and therapeutic uses thereof
WO2020231809A1 (en) 2019-05-10 2020-11-19 Lyvgen Biopharma Co., Ltd. Humanized anti-cd137 antibodies and uses thereof
EP4149964A2 (en) 2020-05-15 2023-03-22 Apogenix AG Multi-specific immune modulators
KR102251580B1 (ko) * 2020-08-14 2021-05-13 최상호 이중 보온관 접속용 레듀사 및 이를 이용한 시공방법
WO2023088876A1 (en) 2021-11-16 2023-05-25 Apogenix Ag Multi-specific immune modulators
WO2023088889A1 (en) 2021-11-16 2023-05-25 Apogenix Ag CD137 ligands
WO2024088404A1 (en) * 2022-10-28 2024-05-02 Fbd Biologics Limited Engineered 4-1bbl variants and methods of use thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1107989B1 (en) * 1998-08-25 2010-03-31 Merck Patent GmbH Expression and export of angiostatin and endostatin as immunofusins
US20030223989A1 (en) * 2002-04-18 2003-12-04 Pluenneke John D. CD137 agonists to treat patients with IgE-mediated conditions
JP2008537941A (ja) 2005-03-31 2008-10-02 ゼンコー・インコーポレイテッド 最適化特性を有するＦｃ変異体
DK2604693T3 (en) * 2008-07-21 2016-05-30 Apogenix Gmbh Single-chain TNFSF molecules
CA2822366A1 (en) 2010-12-23 2012-06-28 Janssen Biotech, Inc. Active protease-resistant antibody fc mutants
US9822179B2 (en) * 2011-04-01 2017-11-21 Universitat Stuttgart Recombinant TNF ligand family member polypeptides with antibody binding domain and uses therefor
US9764038B2 (en) * 2011-12-23 2017-09-19 Innate Pharma Enzymatic conjugation of antibodies
CN108430492B (zh) 2015-10-23 2022-05-03 阿珀吉科吉尼科斯股份公司 单链cd27受体激动剂蛋白
AU2016342420B2 (en) 2015-10-23 2020-10-01 Apogenix Ag Single-chain LIGHT receptor agonist proteins

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