JP2019163319A5 - - Google Patents
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- JP2019163319A5 JP2019163319A5 JP2019104081A JP2019104081A JP2019163319A5 JP 2019163319 A5 JP2019163319 A5 JP 2019163319A5 JP 2019104081 A JP2019104081 A JP 2019104081A JP 2019104081 A JP2019104081 A JP 2019104081A JP 2019163319 A5 JP2019163319 A5 JP 2019163319A5
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- JP
- Japan
- Prior art keywords
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- acid sequence
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021081392A JP7162695B2 (ja) | 2013-11-21 | 2021-05-13 | 抗体－薬物コンジュゲート凍結乾燥製剤 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361907001P | 2013-11-21 | 2013-11-21 | |
| US61/907,001 | 2013-11-21 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016533019A Division JP6590803B2 (ja) | 2013-11-21 | 2014-11-21 | 抗体−薬物コンジュゲート凍結乾燥製剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021081392A Division JP7162695B2 (ja) | 2013-11-21 | 2021-05-13 | 抗体－薬物コンジュゲート凍結乾燥製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019163319A JP2019163319A (ja) | 2019-09-26 |
| JP2019163319A5 true JP2019163319A5 (https=) | 2020-03-19 |
Family
ID=51947368
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016533019A Active JP6590803B2 (ja) | 2013-11-21 | 2014-11-21 | 抗体−薬物コンジュゲート凍結乾燥製剤 |
| JP2019104081A Pending JP2019163319A (ja) | 2013-11-21 | 2019-06-04 | 抗体−薬物コンジュゲート凍結乾燥製剤 |
| JP2021081392A Active JP7162695B2 (ja) | 2013-11-21 | 2021-05-13 | 抗体－薬物コンジュゲート凍結乾燥製剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016533019A Active JP6590803B2 (ja) | 2013-11-21 | 2014-11-21 | 抗体−薬物コンジュゲート凍結乾燥製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021081392A Active JP7162695B2 (ja) | 2013-11-21 | 2021-05-13 | 抗体－薬物コンジュゲート凍結乾燥製剤 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US10617764B2 (https=) |
| EP (2) | EP4420729A3 (https=) |
| JP (3) | JP6590803B2 (https=) |
| KR (1) | KR102372245B1 (https=) |
| CN (2) | CN106163567B (https=) |
| DK (1) | DK3071237T3 (https=) |
| ES (1) | ES2983564T3 (https=) |
| FI (1) | FI3071237T3 (https=) |
| HR (1) | HRP20241036T1 (https=) |
| HU (1) | HUE068207T2 (https=) |
| MX (1) | MX377841B (https=) |
| PL (1) | PL3071237T3 (https=) |
| PT (1) | PT3071237T (https=) |
| SI (1) | SI3071237T1 (https=) |
| WO (1) | WO2015075201A1 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6055404B2 (ja) * | 2010-06-15 | 2016-12-27 | ゲンマブ エー／エス | 組織因子に対するヒト抗体薬物結合体 |
| HUE033369T2 (en) | 2012-11-20 | 2017-11-28 | Sanofi Sa | Anti-ceacam5 antibodies and uses thereof |
| KR102372245B1 (ko) * | 2013-11-21 | 2022-03-08 | 젠맵 에이/에스 | 항체-약물 접합체 동결건조 제제 |
| HRP20210547T1 (hr) * | 2015-07-10 | 2021-05-14 | Byondis B.V. | Sastavi koji sadrže konjugate lijeka antitijela-duocarmycin |
| HUE055109T2 (hu) | 2015-09-11 | 2021-11-29 | Genmab As | Adagolási rendek TF elleni antitest és gyógyszer konjugátumaihoz |
| PT3380525T (pt) * | 2015-11-25 | 2024-02-05 | Immunogen Inc | Formulações farmacêuticas e métodos que as utilizam |
| SG11201805534TA (en) | 2016-01-13 | 2018-07-30 | Genmab As | Formulation for antibody and drug conjugate thereof |
| SI3475303T1 (sl) * | 2016-06-27 | 2021-12-31 | Morphosys Ag | Formulacija protitelesa proti CD19 |
| CN106938051B (zh) * | 2016-08-22 | 2019-10-11 | 复旦大学 | 靶向于组织因子的抗体-药物偶联物 |
| EP3735271A4 (en) | 2018-01-04 | 2022-06-15 | Iconic Therapeutics, Inc. | ANTI-TISSUE FACTOR ANTIBODIES, ANTIBODY DRUG CONJUGATES AND RELATED METHODS |
| TWI841554B (zh) | 2018-03-21 | 2024-05-11 | 丹麥商珍美寶股份有限公司 | 以鉑為主之劑與抗組織因子抗體－藥物共軛物的組合治療癌症之方法 |
| CR20250325A (es) * | 2018-04-13 | 2025-08-29 | Genentech Inc | Formulaciones inmunoconjugadas anti-cd79b estables (divisional expediente 2020-0550) |
| WO2019217455A1 (en) | 2018-05-07 | 2019-11-14 | Genmab A/S | Methods of treating cancer with a combination of an anti-pd-1 antibody and an anti-tissue factor antibody-drug conjugate |
| WO2019217457A1 (en) | 2018-05-07 | 2019-11-14 | Genmab A/S | Methods of treating cancer with a combination of an anti-pd-1 antibody and an anti-tissue factor antibody-drug conjugate |
| AU2019321442A1 (en) * | 2018-08-16 | 2021-02-11 | Genmab A/S | Anti-tissue factor antibody-drug conjugates and their use in the treatment of cancer |
| TWI844571B (zh) | 2018-10-30 | 2024-06-11 | 丹麥商珍美寶股份有限公司 | 使用抗血管內皮生長因子（ｖｅｇｆ）抗體與抗組織因子（ｔｆ）抗體－藥物共軛體之組合以治療癌症之方法 |
| KR102735988B1 (ko) | 2019-02-18 | 2024-12-03 | 일라이 릴리 앤드 캄파니 | 치료 항체 제제 |
| WO2021030665A1 (en) * | 2019-08-15 | 2021-02-18 | Silverback Therapeutics, Inc. | Formulations of benzazepine conjugates and uses thereof |
| TW202131954A (zh) | 2019-11-07 | 2021-09-01 | 丹麥商珍美寶股份有限公司 | 利用鉑類劑與抗組織因子抗體－藥物共軛體之組合來治療癌症之方法 |
| MX2022005222A (es) | 2019-11-07 | 2022-06-08 | Genmab As | Metodos para tratar el cancer con una combinacion de un anticuerpo anti muerte programada 1 (pd-1) y un conjugado de anticuerpo anti factor tisular-farmaco. |
| MX2022015375A (es) | 2020-06-29 | 2023-01-16 | Genmab As | Conjugados de farmaco-anticuerpo anti-factor de tejido y su uso en el tratamiento de cancer. |
| US12564642B2 (en) | 2020-11-10 | 2026-03-03 | Sanofi | CEACAM5 antibody-drug conjugate formulation |
| JP2024533395A (ja) * | 2021-09-08 | 2024-09-12 | 同宜医藥（蘇州）有限公司 | 薬物製剤及びその製造方法と用途 |
| CA3235106A1 (en) * | 2021-10-19 | 2023-04-27 | Sixiang FAN | Conjugate pharmaceutical preparation, preparation method therefor and use thereof______________ |
| CN117045634B (zh) * | 2022-05-06 | 2025-10-10 | 北京康蒂尼药业股份有限公司 | 一种二肽衍生物组合物及其制备方法和用途 |
| WO2023213960A1 (en) | 2022-05-06 | 2023-11-09 | Genmab A/S | Methods of treating cancer with anti-tissue factor antibody-drug conjugates |
| IL319963A (en) | 2022-10-19 | 2025-05-01 | Multitude Therapeutics Inc | Antibodies, antibody-drug conjugates, compositions and uses thereof |
| CN115656496A (zh) * | 2022-10-28 | 2023-01-31 | 迪瑞医疗科技股份有限公司 | 一种普适型冻干保护剂及其应用 |
| TW202448934A (zh) * | 2023-04-28 | 2024-12-16 | 大陸商江蘇恆瑞醫藥股份有限公司 | 抗tf抗體和抗tf抗體-藥物偶聯物及其醫藥用途 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223427A (en) * | 1987-03-31 | 1993-06-29 | The Scripps Research Institute | Hybridomas producing monoclonal antibodies reactive with human tissue-factor glycoprotein heavy chain |
| WO1989011297A1 (en) * | 1988-05-27 | 1989-11-30 | Centocor, Inc. | Freeze-dried formulation for antibody products |
| WO1994005328A1 (en) * | 1992-08-28 | 1994-03-17 | The Scripps Research Institute | Inhibition of tumor metastasis via neutralization of tissue factor function |
| US5635483A (en) | 1992-12-03 | 1997-06-03 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Tumor inhibiting tetrapeptide bearing modified phenethyl amides |
| US5780588A (en) | 1993-01-26 | 1998-07-14 | Arizona Board Of Regents | Elucidation and synthesis of selected pentapeptides |
| US6214345B1 (en) | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
| US5663149A (en) | 1994-12-13 | 1997-09-02 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides |
| CA2226575C (en) | 1995-07-27 | 2011-10-18 | Genentech, Inc. | Stabile isotonic lyophilized protein formulation |
| US5986065A (en) * | 1997-03-10 | 1999-11-16 | Sunol Molecular Corporation | Antibodies for inhibiting blood coagulation and methods of use thereof |
| EP0999853B1 (en) | 1997-06-13 | 2003-01-02 | Genentech, Inc. | Stabilized antibody formulation |
| WO2002011753A1 (en) | 2000-08-04 | 2002-02-14 | Chugai Seiyaku Kabushiki Kaisha | Protein injection preparations |
| GB0113179D0 (en) | 2001-05-31 | 2001-07-25 | Novartis Ag | Organic compounds |
| CA2454587C (en) | 2001-07-25 | 2012-11-13 | Protein Design Labs, Inc. | Stable lyophilized pharmaceutical formulation of igg antibodies |
| JP5290489B2 (ja) | 2001-11-08 | 2013-09-18 | アッヴィ・バイオセラピューティクス・インコーポレイテッド | Ｉｇｇ抗体の安定な液体医薬製剤 |
| WO2004004639A2 (en) | 2002-07-02 | 2004-01-15 | Smithkline Beecham Corporation | A novel stable formulation |
| AU2003242506A1 (en) * | 2002-07-12 | 2004-02-02 | Novo Nordisk A/S | Tf antagonist |
| US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
| AU2003293543A1 (en) | 2002-12-13 | 2004-07-09 | Abgenix, Inc. | System and method for stabilizing antibodies with histidine |
| RU2358763C2 (ru) | 2003-02-10 | 2009-06-20 | Элан Фармасьютикалз, Инк. | Композиции иммуноглобулина и способ их получения |
| US7605235B2 (en) * | 2003-05-30 | 2009-10-20 | Centocor, Inc. | Anti-tissue factor antibodies and compositions |
| US7498298B2 (en) | 2003-11-06 | 2009-03-03 | Seattle Genetics, Inc. | Monomethylvaline compounds capable of conjugation to ligands |
| WO2006014965A2 (en) | 2004-07-27 | 2006-02-09 | Human Genome Sciences, Inc. | Pharmaceutical formulation and process |
| US20070196364A1 (en) * | 2004-07-27 | 2007-08-23 | Human Genome Sciences, Inc. | Pharmaceutical Formulation and Process |
| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| JP2007034443A (ja) * | 2005-07-22 | 2007-02-08 | Konica Minolta Business Technologies Inc | 画像形成システム、画像形成装置及び画像形成処理方法 |
| CN101237881B (zh) * | 2005-08-03 | 2015-04-22 | 伊缪诺金公司 | 免疫偶联物剂型 |
| WO2007019232A2 (en) * | 2005-08-03 | 2007-02-15 | Immunogen, Inc. | Immunoconjugate formulations |
| US10155816B2 (en) | 2005-11-28 | 2018-12-18 | Genmab A/S | Recombinant monovalent antibodies and methods for production thereof |
| CA2686225A1 (en) * | 2007-06-22 | 2008-12-31 | Scidose Llc | Solubilized formulation of docetaxel without tween 80 |
| KR20090001217A (ko) * | 2007-06-29 | 2009-01-08 | 삼성전자주식회사 | 미싱 노즐 검출방법 및 이를 이용하는 잉크젯 프린트 헤드 |
| JP4824710B2 (ja) * | 2008-02-08 | 2011-11-30 | 国立清華大学 | グラフト共重合体およびブロック共重合体の多機能混合ミセルならびにその製造方法 |
| UA109633C2 (uk) | 2008-12-09 | 2015-09-25 | Антитіло людини проти тканинного фактора | |
| JP5005023B2 (ja) * | 2009-12-25 | 2012-08-22 | インターナショナル・ビジネス・マシーンズ・コーポレーション | 読出し及び書込み命令の混在するコマンド列を受け取った場合の最適な書込みを実行するリニア記録方式の装置、その方法、及びプログラム。 |
| EP3511342B1 (en) | 2010-03-10 | 2024-01-17 | Genmab A/S | Monoclonal antibodies against c-met |
| CN104998269B (zh) * | 2010-03-22 | 2019-06-11 | 弗·哈夫曼-拉罗切有限公司 | 对于稳定含有蛋白质的制剂有用的组合物和方法 |
| JP6055404B2 (ja) * | 2010-06-15 | 2016-12-27 | ゲンマブ エー／エス | 組織因子に対するヒト抗体薬物結合体 |
| KR102372245B1 (ko) * | 2013-11-21 | 2022-03-08 | 젠맵 에이/에스 | 항체-약물 접합체 동결건조 제제 |
| HUE055109T2 (hu) | 2015-09-11 | 2021-11-29 | Genmab As | Adagolási rendek TF elleni antitest és gyógyszer konjugátumaihoz |
-
2014
- 2014-11-21 KR KR1020167016066A patent/KR102372245B1/ko active Active
- 2014-11-21 JP JP2016533019A patent/JP6590803B2/ja active Active
- 2014-11-21 WO PCT/EP2014/075326 patent/WO2015075201A1/en not_active Ceased
- 2014-11-21 PL PL14802428.4T patent/PL3071237T3/pl unknown
- 2014-11-21 US US15/038,235 patent/US10617764B2/en active Active
- 2014-11-21 SI SI201432096T patent/SI3071237T1/sl unknown
- 2014-11-21 DK DK14802428.4T patent/DK3071237T3/da active
- 2014-11-21 HR HRP20241036TT patent/HRP20241036T1/hr unknown
- 2014-11-21 EP EP24177039.5A patent/EP4420729A3/en not_active Withdrawn
- 2014-11-21 CN CN201480073804.2A patent/CN106163567B/zh active Active
- 2014-11-21 EP EP14802428.4A patent/EP3071237B1/en active Active
- 2014-11-21 MX MX2016006488A patent/MX377841B/es unknown
- 2014-11-21 PT PT148024284T patent/PT3071237T/pt unknown
- 2014-11-21 HU HUE14802428A patent/HUE068207T2/hu unknown
- 2014-11-21 CN CN202110607250.1A patent/CN113521016A/zh active Pending
- 2014-11-21 ES ES14802428T patent/ES2983564T3/es active Active
- 2014-11-21 FI FIEP14802428.4T patent/FI3071237T3/fi active
-
2019
- 2019-06-04 JP JP2019104081A patent/JP2019163319A/ja active Pending
-
2020
- 2020-01-14 US US16/742,158 patent/US20200246477A1/en not_active Abandoned
-
2021
- 2021-05-13 JP JP2021081392A patent/JP7162695B2/ja active Active
-
2022
- 2022-12-13 US US18/065,196 patent/US20240091373A1/en not_active Abandoned
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