JP2019163319A5 - - Google Patents
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- JP2019163319A5 JP2019163319A5 JP2019104081A JP2019104081A JP2019163319A5 JP 2019163319 A5 JP2019163319 A5 JP 2019163319A5 JP 2019104081 A JP2019104081 A JP 2019104081A JP 2019104081 A JP2019104081 A JP 2019104081A JP 2019163319 A5 JP2019163319 A5 JP 2019163319A5
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- JP
- Japan
- Prior art keywords
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- acid sequence
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021081392A JP7162695B2 (ja) | 2013-11-21 | 2021-05-13 | 抗体－薬物コンジュゲート凍結乾燥製剤 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361907001P | 2013-11-21 | 2013-11-21 | |
| US61/907,001 | 2013-11-21 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016533019A Division JP6590803B2 (ja) | 2013-11-21 | 2014-11-21 | 抗体−薬物コンジュゲート凍結乾燥製剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021081392A Division JP7162695B2 (ja) | 2013-11-21 | 2021-05-13 | 抗体－薬物コンジュゲート凍結乾燥製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019163319A JP2019163319A (ja) | 2019-09-26 |
| JP2019163319A5 true JP2019163319A5 (https=) | 2020-03-19 |
Family
ID=51947368
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016533019A Active JP6590803B2 (ja) | 2013-11-21 | 2014-11-21 | 抗体−薬物コンジュゲート凍結乾燥製剤 |
| JP2019104081A Pending JP2019163319A (ja) | 2013-11-21 | 2019-06-04 | 抗体−薬物コンジュゲート凍結乾燥製剤 |
| JP2021081392A Active JP7162695B2 (ja) | 2013-11-21 | 2021-05-13 | 抗体－薬物コンジュゲート凍結乾燥製剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016533019A Active JP6590803B2 (ja) | 2013-11-21 | 2014-11-21 | 抗体−薬物コンジュゲート凍結乾燥製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021081392A Active JP7162695B2 (ja) | 2013-11-21 | 2021-05-13 | 抗体－薬物コンジュゲート凍結乾燥製剤 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US10617764B2 (https=) |
| EP (2) | EP3071237B1 (https=) |
| JP (3) | JP6590803B2 (https=) |
| KR (1) | KR102372245B1 (https=) |
| CN (2) | CN113521016A (https=) |
| DK (1) | DK3071237T3 (https=) |
| ES (1) | ES2983564T3 (https=) |
| FI (1) | FI3071237T3 (https=) |
| HR (1) | HRP20241036T1 (https=) |
| HU (1) | HUE068207T2 (https=) |
| MX (1) | MX377841B (https=) |
| PL (1) | PL3071237T3 (https=) |
| PT (1) | PT3071237T (https=) |
| SI (1) | SI3071237T1 (https=) |
| WO (1) | WO2015075201A1 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112012031727B1 (pt) * | 2010-06-15 | 2022-03-29 | Genmab A/S | Conjugado de droga-anticorpo, composição farmacêutica, e, uso do conjugado de droga- anticorpo |
| DK3199552T3 (da) | 2012-11-20 | 2020-03-30 | Sanofi Sa | Anti-ceacam5-antistoffer og anvendelser heraf |
| SI3071237T1 (sl) * | 2013-11-21 | 2024-11-29 | Genmab A/S | Liofilizirana formulacija konjugata protitelo-zdravilo |
| PL3319597T3 (pl) * | 2015-07-10 | 2021-10-11 | Byondis B.V. | Kompozycje zawierające koniugaty przeciwciało-duokarmycyna |
| PT3347054T (pt) | 2015-09-11 | 2021-07-15 | Genmab As | Regimes de dosagem para conjugados fármaco-anticorpo anti-tf |
| US20170189548A1 (en) | 2015-11-25 | 2017-07-06 | Immunogen, Inc. | Pharmaceutical formulations and methods of use thereof |
| KR20180101479A (ko) * | 2016-01-13 | 2018-09-12 | 젠맵 에이/에스 | 항체 및 그의 약물 접합체를 위한 제제 |
| WO2018002031A1 (en) | 2016-06-27 | 2018-01-04 | Morphosys Ag | Anti-cd19 antibody formulations |
| CN106938051B (zh) | 2016-08-22 | 2019-10-11 | 复旦大学 | 靶向于组织因子的抗体-药物偶联物 |
| MX2020007077A (es) | 2018-01-04 | 2020-10-28 | Iconic Therapeutics Inc | Anticuerpos anti-factor tisular, conjugados anticuerpo-farmaco y metodos relacionados. |
| TWI841554B (zh) | 2018-03-21 | 2024-05-11 | 丹麥商珍美寶股份有限公司 | 以鉑為主之劑與抗組織因子抗體－藥物共軛物的組合治療癌症之方法 |
| CR20250325A (es) * | 2018-04-13 | 2025-08-29 | Genentech Inc | Formulaciones inmunoconjugadas anti-cd79b estables (divisional expediente 2020-0550) |
| UA129352C2 (uk) | 2018-05-07 | 2025-03-26 | Генмаб А/С | Способи лікування раку за допомогою комбінації антитіла до pd-1 і кон'югата антитіла до тканинного фактора та лікарського засобу |
| TW202506732A (zh) * | 2018-05-07 | 2025-02-16 | 丹麥商珍美寶股份有限公司 | 使用抗ｐｄ－１抗體與抗組織因子抗體－藥物共軛體之組合以治療癌症之方法 |
| MX2021001058A (es) * | 2018-08-16 | 2021-04-12 | Genmab As | Conjugados de anticuerpo anti-factor tisular-farmaco y su uso en el tratamiento de un cancer. |
| TWI844571B (zh) | 2018-10-30 | 2024-06-11 | 丹麥商珍美寶股份有限公司 | 使用抗血管內皮生長因子（ｖｅｇｆ）抗體與抗組織因子（ｔｆ）抗體－藥物共軛體之組合以治療癌症之方法 |
| CN120241997A (zh) | 2019-02-18 | 2025-07-04 | 伊莱利利公司 | 治疗性抗体制剂 |
| CN114667134A (zh) * | 2019-08-15 | 2022-06-24 | 希沃尔拜克治疗公司 | 苯并氮杂䓬缀合物的制剂及其用途 |
| TW202132343A (zh) | 2019-11-07 | 2021-09-01 | 丹麥商珍美寶股份有限公司 | 使用抗ｐｄ－１抗體與抗組織因子抗體－藥物共軛體之組合以治療癌症之方法 |
| TW202131954A (zh) | 2019-11-07 | 2021-09-01 | 丹麥商珍美寶股份有限公司 | 利用鉑類劑與抗組織因子抗體－藥物共軛體之組合來治療癌症之方法 |
| EP4171652A1 (en) | 2020-06-29 | 2023-05-03 | Genmab A/S | Anti-tissue factor antibody-drug conjugates and their use in the treatment of cancer |
| AU2021379882A1 (en) | 2020-11-10 | 2023-06-29 | Sanofi | Ceacam5 antibody-drug conjugate formulation |
| JP2024533395A (ja) * | 2021-09-08 | 2024-09-12 | 同宜医藥（蘇州）有限公司 | 薬物製剤及びその製造方法と用途 |
| TW202327659A (zh) * | 2021-10-19 | 2023-07-16 | 大陸商同宜醫藥（蘇州）有限公司 | 偶聯體藥物製劑及其製備方法和用途 |
| WO2023213960A1 (en) | 2022-05-06 | 2023-11-09 | Genmab A/S | Methods of treating cancer with anti-tissue factor antibody-drug conjugates |
| CN117045634B (zh) * | 2022-05-06 | 2025-10-10 | 北京康蒂尼药业股份有限公司 | 一种二肽衍生物组合物及其制备方法和用途 |
| WO2024083162A1 (en) | 2022-10-19 | 2024-04-25 | Multitude Therapeutics Inc. | Antibodies, antibody-drug conjugates, preparations and uses thereof |
| CN115656496A (zh) * | 2022-10-28 | 2023-01-31 | 迪瑞医疗科技股份有限公司 | 一种普适型冻干保护剂及其应用 |
| CN121039165A (zh) * | 2023-04-28 | 2025-11-28 | 江苏恒瑞医药股份有限公司 | 抗tf抗体和抗tf抗体-药物偶联物及其医药用途 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223427A (en) * | 1987-03-31 | 1993-06-29 | The Scripps Research Institute | Hybridomas producing monoclonal antibodies reactive with human tissue-factor glycoprotein heavy chain |
| DE68908175T2 (de) * | 1988-05-27 | 1994-03-03 | Centocor Inc | Gefriergetrocknete formulierung für antikörperprodukte. |
| AU5093593A (en) * | 1992-08-28 | 1994-03-29 | Scripps Research Institute, The | Inhibition of tumor metastasis via neutralization of tissue factor function |
| US5635483A (en) | 1992-12-03 | 1997-06-03 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Tumor inhibiting tetrapeptide bearing modified phenethyl amides |
| US5780588A (en) | 1993-01-26 | 1998-07-14 | Arizona Board Of Regents | Elucidation and synthesis of selected pentapeptides |
| US6214345B1 (en) | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
| US5663149A (en) | 1994-12-13 | 1997-09-02 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides |
| ES2434840T3 (es) | 1995-07-27 | 2013-12-17 | Genentech, Inc. | Formulación de proteína liofilizada isotónica estable |
| US5986065A (en) * | 1997-03-10 | 1999-11-16 | Sunol Molecular Corporation | Antibodies for inhibiting blood coagulation and methods of use thereof |
| CA2635352C (en) | 1997-06-13 | 2012-09-11 | Genentech, Inc. | Stabilized antibody formulation |
| JP5490972B2 (ja) | 2000-08-04 | 2014-05-14 | 中外製薬株式会社 | タンパク質注射製剤 |
| GB0113179D0 (en) | 2001-05-31 | 2001-07-25 | Novartis Ag | Organic compounds |
| MXPA04000747A (es) * | 2001-07-25 | 2004-07-08 | Protein Desing Labs Inc | Formulacion farmaceutica liofilizada estable de anticuerpos igg. |
| IL161677A0 (en) | 2001-11-08 | 2004-09-27 | Protein Design Labs | Stable liquid pharmaceutical formulation of igg antibodies |
| JP2005532395A (ja) | 2002-07-02 | 2005-10-27 | スミスクライン・ビーチャム・コーポレイション | 新規な安定処方 |
| AU2003242506A1 (en) * | 2002-07-12 | 2004-02-02 | Novo Nordisk A/S | Tf antagonist |
| US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
| AU2003293543A1 (en) | 2002-12-13 | 2004-07-09 | Abgenix, Inc. | System and method for stabilizing antibodies with histidine |
| DK2236154T3 (en) | 2003-02-10 | 2018-06-25 | Biogen Ma Inc | IMMUNOGLOBULIN INFORMATION AND METHOD OF PREPARING IT |
| US7605235B2 (en) * | 2003-05-30 | 2009-10-20 | Centocor, Inc. | Anti-tissue factor antibodies and compositions |
| EP2478912B1 (en) | 2003-11-06 | 2016-08-31 | Seattle Genetics, Inc. | Auristatin conjugates with anti-HER2 or anti-CD22 antibodies and their use in therapy |
| WO2006014965A2 (en) | 2004-07-27 | 2006-02-09 | Human Genome Sciences, Inc. | Pharmaceutical formulation and process |
| US20070196364A1 (en) * | 2004-07-27 | 2007-08-23 | Human Genome Sciences, Inc. | Pharmaceutical Formulation and Process |
| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| JP2007034443A (ja) * | 2005-07-22 | 2007-02-08 | Konica Minolta Business Technologies Inc | 画像形成システム、画像形成装置及び画像形成処理方法 |
| WO2007019232A2 (en) * | 2005-08-03 | 2007-02-15 | Immunogen, Inc. | Immunoconjugate formulations |
| ZA200800146B (en) * | 2005-08-03 | 2009-10-28 | Immunogen Inc | Immunoconjugate formulations |
| CA2631184A1 (en) | 2005-11-28 | 2007-05-31 | Genmab A/S | Recombinant monovalent antibodies and methods for production thereof |
| WO2009002425A2 (en) | 2007-06-22 | 2008-12-31 | Scidose Llc | Solubilized formulation of docetaxel without tween 80 |
| KR20090001217A (ko) * | 2007-06-29 | 2009-01-08 | 삼성전자주식회사 | 미싱 노즐 검출방법 및 이를 이용하는 잉크젯 프린트 헤드 |
| JP4824710B2 (ja) * | 2008-02-08 | 2011-11-30 | 国立清華大学 | グラフト共重合体およびブロック共重合体の多機能混合ミセルならびにその製造方法 |
| UA109633C2 (uk) | 2008-12-09 | 2015-09-25 | Антитіло людини проти тканинного фактора | |
| JP5005023B2 (ja) * | 2009-12-25 | 2012-08-22 | インターナショナル・ビジネス・マシーンズ・コーポレーション | 読出し及び書込み命令の混在するコマンド列を受け取った場合の最適な書込みを実行するリニア記録方式の装置、その方法、及びプログラム。 |
| PT3904391T (pt) | 2010-03-10 | 2024-10-14 | Genmab As | Anticorpos monoclonais contra c-met |
| EP2550018B1 (en) | 2010-03-22 | 2019-02-27 | F.Hoffmann-La Roche Ag | Compositions and methods useful for stabilizing protein-containing formulations |
| BR112012031727B1 (pt) * | 2010-06-15 | 2022-03-29 | Genmab A/S | Conjugado de droga-anticorpo, composição farmacêutica, e, uso do conjugado de droga- anticorpo |
| SI3071237T1 (sl) * | 2013-11-21 | 2024-11-29 | Genmab A/S | Liofilizirana formulacija konjugata protitelo-zdravilo |
| PT3347054T (pt) | 2015-09-11 | 2021-07-15 | Genmab As | Regimes de dosagem para conjugados fármaco-anticorpo anti-tf |
-
2014
- 2014-11-21 SI SI201432096T patent/SI3071237T1/sl unknown
- 2014-11-21 HR HRP20241036TT patent/HRP20241036T1/hr unknown
- 2014-11-21 PL PL14802428.4T patent/PL3071237T3/pl unknown
- 2014-11-21 ES ES14802428T patent/ES2983564T3/es active Active
- 2014-11-21 MX MX2016006488A patent/MX377841B/es unknown
- 2014-11-21 KR KR1020167016066A patent/KR102372245B1/ko active Active
- 2014-11-21 EP EP14802428.4A patent/EP3071237B1/en active Active
- 2014-11-21 JP JP2016533019A patent/JP6590803B2/ja active Active
- 2014-11-21 PT PT148024284T patent/PT3071237T/pt unknown
- 2014-11-21 EP EP24177039.5A patent/EP4420729A3/en not_active Withdrawn
- 2014-11-21 HU HUE14802428A patent/HUE068207T2/hu unknown
- 2014-11-21 CN CN202110607250.1A patent/CN113521016A/zh active Pending
- 2014-11-21 WO PCT/EP2014/075326 patent/WO2015075201A1/en not_active Ceased
- 2014-11-21 US US15/038,235 patent/US10617764B2/en active Active
- 2014-11-21 DK DK14802428.4T patent/DK3071237T3/da active
- 2014-11-21 FI FIEP14802428.4T patent/FI3071237T3/fi active
- 2014-11-21 CN CN201480073804.2A patent/CN106163567B/zh active Active
-
2019
- 2019-06-04 JP JP2019104081A patent/JP2019163319A/ja active Pending
-
2020
- 2020-01-14 US US16/742,158 patent/US20200246477A1/en not_active Abandoned
-
2021
- 2021-05-13 JP JP2021081392A patent/JP7162695B2/ja active Active
-
2022
- 2022-12-13 US US18/065,196 patent/US20240091373A1/en not_active Abandoned
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