JP2019089799A5 - - Google Patents

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JP2019089799A5
JP2019089799A5 JP2019010528A JP2019010528A JP2019089799A5 JP 2019089799 A5 JP2019089799 A5 JP 2019089799A5 JP 2019010528 A JP2019010528 A JP 2019010528A JP 2019010528 A JP2019010528 A JP 2019010528A JP 2019089799 A5 JP2019089799 A5 JP 2019089799A5
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pharmaceutical composition
composition according
ttr
dsrna
expression
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JP6669905B2 (ja
JP2019089799A (ja
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JP2019010528A 2010-03-29 2019-01-24 トランスチレチン(TTR)関連眼アミロイドーシスのためのsiRNA療法 Active JP6669905B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US31870210P 2010-03-29 2010-03-29
US31870410P 2010-03-29 2010-03-29
US61/318,704 2010-03-29
US61/318,702 2010-03-29

Related Parent Applications (1)

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JP2017157474A Division JP2018012708A (ja) 2010-03-29 2017-08-17 トランスチレチン(TTR)関連眼アミロイドーシスのためのsiRNA療法

Publications (3)

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JP2019089799A JP2019089799A (ja) 2019-06-13
JP2019089799A5 true JP2019089799A5 (enExample) 2019-09-05
JP6669905B2 JP6669905B2 (ja) 2020-03-18

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JP2013502765A Active JP5860029B2 (ja) 2010-03-29 2011-03-29 トランスチレチン(TTR)関連眼アミロイドーシスのためのsiRNA療法
JP2015182463A Pending JP2016027814A (ja) 2010-03-29 2015-09-16 トランスチレチン(TTR)関連眼アミロイドーシスのためのsiRNA療法
JP2017157474A Pending JP2018012708A (ja) 2010-03-29 2017-08-17 トランスチレチン(TTR)関連眼アミロイドーシスのためのsiRNA療法
JP2019010528A Active JP6669905B2 (ja) 2010-03-29 2019-01-24 トランスチレチン(TTR)関連眼アミロイドーシスのためのsiRNA療法

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JP2013502765A Active JP5860029B2 (ja) 2010-03-29 2011-03-29 トランスチレチン(TTR)関連眼アミロイドーシスのためのsiRNA療法
JP2015182463A Pending JP2016027814A (ja) 2010-03-29 2015-09-16 トランスチレチン(TTR)関連眼アミロイドーシスのためのsiRNA療法
JP2017157474A Pending JP2018012708A (ja) 2010-03-29 2017-08-17 トランスチレチン(TTR)関連眼アミロイドーシスのためのsiRNA療法

Country Status (7)

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US (6) US20130281510A1 (enExample)
EP (2) EP3329924B1 (enExample)
JP (4) JP5860029B2 (enExample)
AU (1) AU2011235276B2 (enExample)
CA (1) CA2792291A1 (enExample)
ES (1) ES2893199T3 (enExample)
WO (1) WO2011123468A1 (enExample)

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CN104693099A (zh) * 2015-02-13 2015-06-10 佛山市赛维斯医药科技有限公司 一种含双酰肼和萘基结构的化合物及其用途
CN104693097A (zh) * 2015-02-13 2015-06-10 佛山市赛维斯医药科技有限公司 一类含双酰肼和烷氧萘基结构的化合物、制备方法及其用途
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EP3684931A1 (en) 2017-09-19 2020-07-29 Alnylam Pharmaceuticals, Inc. Compositions and methods for treating transthyretin (ttr) mediated amyloidosis
US11851654B2 (en) 2018-03-19 2023-12-26 National University Corporation Tokyo Medical And Dental University Nucleic acid with reduced toxicity
US20220175816A1 (en) * 2019-04-18 2022-06-09 University Of Massachusetts Aim2 inhibitors and uses thereof
JP7692829B2 (ja) 2019-07-30 2025-06-16 塩野義製薬株式会社 Murf1を標的とする核酸医薬
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