JP2018538003A5 - - Google Patents
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- Publication number
- JP2018538003A5 JP2018538003A5 JP2018533200A JP2018533200A JP2018538003A5 JP 2018538003 A5 JP2018538003 A5 JP 2018538003A5 JP 2018533200 A JP2018533200 A JP 2018533200A JP 2018533200 A JP2018533200 A JP 2018533200A JP 2018538003 A5 JP2018538003 A5 JP 2018538003A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- expression cassette
- vector
- acid expression
- regulatory element
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021040766A JP7376018B2 (ja) | 2015-12-22 | 2021-03-12 | 内皮特異的核酸調節エレメントならびにその方法および使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2015081075 | 2015-12-22 | ||
| EPPCT/EP2015/081075 | 2015-12-22 | ||
| PCT/EP2016/082314 WO2017109039A1 (en) | 2015-12-22 | 2016-12-22 | Endothelium-specific nucleic acid regulatory elements and methods and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021040766A Division JP7376018B2 (ja) | 2015-12-22 | 2021-03-12 | 内皮特異的核酸調節エレメントならびにその方法および使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018538003A JP2018538003A (ja) | 2018-12-27 |
| JP2018538003A5 true JP2018538003A5 (enExample) | 2020-02-06 |
Family
ID=57821918
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018533200A Pending JP2018538003A (ja) | 2015-12-22 | 2016-12-22 | 内皮特異的核酸調節エレメントならびにその方法および使用 |
| JP2021040766A Active JP7376018B2 (ja) | 2015-12-22 | 2021-03-12 | 内皮特異的核酸調節エレメントならびにその方法および使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021040766A Active JP7376018B2 (ja) | 2015-12-22 | 2021-03-12 | 内皮特異的核酸調節エレメントならびにその方法および使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11446375B2 (enExample) |
| EP (1) | EP3393523B9 (enExample) |
| JP (2) | JP2018538003A (enExample) |
| AU (1) | AU2016378480A1 (enExample) |
| CA (1) | CA3009264A1 (enExample) |
| WO (1) | WO2017109039A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT201700086403A1 (it) * | 2017-07-27 | 2019-01-27 | Univ Del Piemonte Orientale | Endothelial-specific promoter sequences and uses thereof |
| EP3870215A1 (en) | 2018-10-26 | 2021-09-01 | Vrije Universiteit Brussel | New tools for improving gene therapy and use thereof |
| CN114651005A (zh) * | 2019-01-24 | 2022-06-21 | 艾克赛尔吉恩公司 | 生产和使用重组α1-抗胰蛋白酶(AAT)及其组合物的方法 |
| EP3923992A1 (en) | 2019-02-15 | 2021-12-22 | CRISPR Therapeutics AG | Gene editing for hemophilia a with improved factor viii expression |
| CN113710284A (zh) * | 2019-06-05 | 2021-11-26 | 克里斯珀医疗股份公司 | 具有改善的因子viii表达的血友病a基因编辑 |
| CN111534541A (zh) * | 2020-05-07 | 2020-08-14 | 西南大学 | 一种真核生物CRISPR-Cas9双gRNA载体及构建方法 |
| JP7853952B2 (ja) * | 2020-08-05 | 2026-04-30 | スペースクラフト セブン リミテッド ライアビリティ カンパニー | Ｇｌｕｔ１発現のためのアデノ随伴ウイルスベクターおよびその使用 |
| US20220233714A1 (en) * | 2021-01-27 | 2022-07-28 | Vanderbilt University | Nanogold-dna bioconjugates and methods of use thereof |
| CN114032239B (zh) * | 2021-10-28 | 2024-06-21 | 北京美康基免生物科技有限公司 | 一种组织特异启动子及其应用 |
| EP4368209A1 (en) | 2022-11-09 | 2024-05-15 | Vrije Universiteit Brussel | Cardiac vascular endothelial cell-derived nucleic acid regulatory elements and methods and use thereof |
| CN117925624B (zh) * | 2024-03-22 | 2024-05-31 | 上海凌医生物科技有限公司 | 一种金属响应调控元件 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5656454A (en) | 1994-10-04 | 1997-08-12 | President And Fellows Of Harvard College | Endothelial cell-specific enhancer |
| FR2756570B1 (fr) * | 1996-12-03 | 2002-09-27 | Commissariat Energie Atomique | Promoteur de la ve-cadherine et ses utilisations |
| AU2003222427B8 (en) | 2000-11-17 | 2010-04-29 | Vascular Biogenics Ltd. | Promoters exhibiting endothelial cell specificity and methods of using same |
| ITMI20011138A1 (it) * | 2001-05-29 | 2002-11-29 | Uni Di Torino | Vettore e metodi di impiego per l'espressione selettiva di geni in siti di angiogenesi in vivo |
| JP2005204549A (ja) | 2004-01-21 | 2005-08-04 | Hubit Genomix Inc | Ｃ型肝炎ウイルス感染者の経過に関する遺伝子およびその利用 |
| US20070161031A1 (en) | 2005-12-16 | 2007-07-12 | The Board Of Trustees Of The Leland Stanford Junior University | Functional arrays for high throughput characterization of gene expression regulatory elements |
| US20090018031A1 (en) * | 2006-12-07 | 2009-01-15 | Switchgear Genomics | Transcriptional regulatory elements of biological pathways tools, and methods |
| US8815779B2 (en) | 2009-09-16 | 2014-08-26 | SwitchGear Genomics, Inc. | Transcription biomarkers of biological responses and methods |
| CA2785677C (en) * | 2009-12-29 | 2019-06-25 | Cornell University | Methods for developing endothelial cells from pluripotent cells and endothelial cells derived therefrom |
| CA2827348C (en) | 2011-02-14 | 2021-02-23 | Revivicor, Inc. | Genetically modified pigs for xenotransplantation of vascularized xenografts and derivatives thereof |
| JP2015109833A (ja) * | 2013-11-08 | 2015-06-18 | 学校法人慶應義塾 | 線維芽細胞から血管内皮細胞を製造する方法 |
-
2016
- 2016-12-22 EP EP16826729.2A patent/EP3393523B9/en active Active
- 2016-12-22 CA CA3009264A patent/CA3009264A1/en active Pending
- 2016-12-22 US US16/065,629 patent/US11446375B2/en active Active
- 2016-12-22 JP JP2018533200A patent/JP2018538003A/ja active Pending
- 2016-12-22 AU AU2016378480A patent/AU2016378480A1/en not_active Abandoned
- 2016-12-22 WO PCT/EP2016/082314 patent/WO2017109039A1/en not_active Ceased
-
2021
- 2021-03-12 JP JP2021040766A patent/JP7376018B2/ja active Active
-
2022
- 2022-07-26 US US17/815,136 patent/US12558416B2/en active Active
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