JP2018538003A5 - - Google Patents

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Publication number
JP2018538003A5
JP2018538003A5 JP2018533200A JP2018533200A JP2018538003A5 JP 2018538003 A5 JP2018538003 A5 JP 2018538003A5 JP 2018533200 A JP2018533200 A JP 2018533200A JP 2018533200 A JP2018533200 A JP 2018533200A JP 2018538003 A5 JP2018538003 A5 JP 2018538003A5
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JP
Japan
Prior art keywords
nucleic acid
expression cassette
vector
acid expression
regulatory element
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018533200A
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English (en)
Japanese (ja)
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JP2018538003A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2016/082314 external-priority patent/WO2017109039A1/en
Publication of JP2018538003A publication Critical patent/JP2018538003A/ja
Publication of JP2018538003A5 publication Critical patent/JP2018538003A5/ja
Priority to JP2021040766A priority Critical patent/JP7376018B2/ja
Pending legal-status Critical Current

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JP2018533200A 2015-12-22 2016-12-22 内皮特異的核酸調節エレメントならびにその方法および使用 Pending JP2018538003A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021040766A JP7376018B2 (ja) 2015-12-22 2021-03-12 内皮特異的核酸調節エレメントならびにその方法および使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/EP2015/081075 2015-12-22
EP2015081075 2015-12-22
PCT/EP2016/082314 WO2017109039A1 (en) 2015-12-22 2016-12-22 Endothelium-specific nucleic acid regulatory elements and methods and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021040766A Division JP7376018B2 (ja) 2015-12-22 2021-03-12 内皮特異的核酸調節エレメントならびにその方法および使用

Publications (2)

Publication Number Publication Date
JP2018538003A JP2018538003A (ja) 2018-12-27
JP2018538003A5 true JP2018538003A5 (enExample) 2020-02-06

Family

ID=57821918

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018533200A Pending JP2018538003A (ja) 2015-12-22 2016-12-22 内皮特異的核酸調節エレメントならびにその方法および使用
JP2021040766A Active JP7376018B2 (ja) 2015-12-22 2021-03-12 内皮特異的核酸調節エレメントならびにその方法および使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021040766A Active JP7376018B2 (ja) 2015-12-22 2021-03-12 内皮特異的核酸調節エレメントならびにその方法および使用

Country Status (6)

Country Link
US (2) US11446375B2 (enExample)
EP (1) EP3393523B9 (enExample)
JP (2) JP2018538003A (enExample)
AU (1) AU2016378480A1 (enExample)
CA (1) CA3009264A1 (enExample)
WO (1) WO2017109039A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201700086403A1 (it) * 2017-07-27 2019-01-27 Univ Del Piemonte Orientale Endothelial-specific promoter sequences and uses thereof
WO2020084161A1 (en) 2018-10-26 2020-04-30 Vrije Universiteit Brussel New tools for improving gene therapy and use thereof
WO2020152653A1 (en) * 2019-01-24 2020-07-30 Excellgene Sa Methods of producing and using recombinant alpha 1-antitrypsin (aat) and compositions thereof
WO2020168362A1 (en) 2019-02-15 2020-08-20 Crispr Therapeutics Ag Gene editing for hemophilia a with improved factor viii expression
JP7585217B2 (ja) * 2019-06-05 2024-11-18 クリスパー セラピューティクス アクチェンゲゼルシャフト 改善された第viii因子発現による血友病aのための遺伝子編集
CN111534541A (zh) * 2020-05-07 2020-08-14 西南大学 一种真核生物CRISPR-Cas9双gRNA载体及构建方法
US20230272422A1 (en) * 2020-08-05 2023-08-31 Spacecraft Seven, Llc Adeno-associated viral vector for glut1 expression and uses thereof
US20220233714A1 (en) * 2021-01-27 2022-07-28 Vanderbilt University Nanogold-dna bioconjugates and methods of use thereof
CN114032239B (zh) * 2021-10-28 2024-06-21 北京美康基免生物科技有限公司 一种组织特异启动子及其应用
EP4368209A1 (en) 2022-11-09 2024-05-15 Vrije Universiteit Brussel Cardiac vascular endothelial cell-derived nucleic acid regulatory elements and methods and use thereof
CN117925624B (zh) * 2024-03-22 2024-05-31 上海凌医生物科技有限公司 一种金属响应调控元件

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656454A (en) * 1994-10-04 1997-08-12 President And Fellows Of Harvard College Endothelial cell-specific enhancer
FR2756570B1 (fr) * 1996-12-03 2002-09-27 Commissariat Energie Atomique Promoteur de la ve-cadherine et ses utilisations
AU2003222427B8 (en) 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
ITMI20011138A1 (it) * 2001-05-29 2002-11-29 Uni Di Torino Vettore e metodi di impiego per l'espressione selettiva di geni in siti di angiogenesi in vivo
JP2005204549A (ja) * 2004-01-21 2005-08-04 Hubit Genomix Inc C型肝炎ウイルス感染者の経過に関する遺伝子およびその利用
US20070161031A1 (en) 2005-12-16 2007-07-12 The Board Of Trustees Of The Leland Stanford Junior University Functional arrays for high throughput characterization of gene expression regulatory elements
EP2097538A4 (en) * 2006-12-07 2011-11-30 Switchgear Genomics TRANSCRIPTION REAGULATION ELEMENTS OF BIOLOGICAL PATHS, TOOLS AND METHODS
US8815779B2 (en) * 2009-09-16 2014-08-26 SwitchGear Genomics, Inc. Transcription biomarkers of biological responses and methods
CA2785677C (en) * 2009-12-29 2019-06-25 Cornell University Methods for developing endothelial cells from pluripotent cells and endothelial cells derived therefrom
CN103492576A (zh) * 2011-02-14 2014-01-01 雷维维科公司 用于血管化异种移植物及其衍生物的异种移植的遗传修饰的猪
JP2015109833A (ja) * 2013-11-08 2015-06-18 学校法人慶應義塾 線維芽細胞から血管内皮細胞を製造する方法

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