JP2018534932A5 - - Google Patents
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- JP2018534932A5 JP2018534932A5 JP2018522662A JP2018522662A JP2018534932A5 JP 2018534932 A5 JP2018534932 A5 JP 2018534932A5 JP 2018522662 A JP2018522662 A JP 2018522662A JP 2018522662 A JP2018522662 A JP 2018522662A JP 2018534932 A5 JP2018534932 A5 JP 2018534932A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- activity
- ion
- small molecule
- assay
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022068158A JP7390748B2 (ja) | 2015-11-02 | 2022-04-18 | 条件的活性型ポリペプチド |
| JP2023193435A JP2024020382A (ja) | 2015-11-02 | 2023-11-14 | 条件的活性型ポリペプチド |
| JP2025185767A JP2026027333A (ja) | 2015-11-02 | 2025-11-04 | 条件的活性型ポリペプチド |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562249907P | 2015-11-02 | 2015-11-02 | |
| US62/249,907 | 2015-11-02 | ||
| USPCT/US2016/019242 | 2016-02-24 | ||
| PCT/US2016/019242 WO2016138071A1 (en) | 2015-02-24 | 2016-02-24 | Conditionally active biological proteins |
| PCT/US2016/049715 WO2017078839A1 (en) | 2015-11-02 | 2016-08-31 | Conditionally active polypeptides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022068158A Division JP7390748B2 (ja) | 2015-11-02 | 2022-04-18 | 条件的活性型ポリペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018534932A JP2018534932A (ja) | 2018-11-29 |
| JP2018534932A5 true JP2018534932A5 (enExample) | 2019-10-10 |
| JP7064769B2 JP7064769B2 (ja) | 2022-05-11 |
Family
ID=58662272
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018522662A Active JP7064769B2 (ja) | 2015-11-02 | 2016-08-31 | 条件的活性型ポリペプチド |
| JP2022068158A Active JP7390748B2 (ja) | 2015-11-02 | 2022-04-18 | 条件的活性型ポリペプチド |
| JP2023193435A Pending JP2024020382A (ja) | 2015-11-02 | 2023-11-14 | 条件的活性型ポリペプチド |
| JP2025185767A Pending JP2026027333A (ja) | 2015-11-02 | 2025-11-04 | 条件的活性型ポリペプチド |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022068158A Active JP7390748B2 (ja) | 2015-11-02 | 2022-04-18 | 条件的活性型ポリペプチド |
| JP2023193435A Pending JP2024020382A (ja) | 2015-11-02 | 2023-11-14 | 条件的活性型ポリペプチド |
| JP2025185767A Pending JP2026027333A (ja) | 2015-11-02 | 2025-11-04 | 条件的活性型ポリペプチド |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11472876B2 (enExample) |
| EP (1) | EP3371349A1 (enExample) |
| JP (4) | JP7064769B2 (enExample) |
| KR (2) | KR102714709B1 (enExample) |
| CN (2) | CN115521374B (enExample) |
| AU (2) | AU2016350613B2 (enExample) |
| CA (1) | CA3003399A1 (enExample) |
| MX (2) | MX2018005063A (enExample) |
| RU (1) | RU2735023C9 (enExample) |
| WO (1) | WO2017078839A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2913205T3 (es) * | 2014-05-13 | 2022-06-01 | Bioatla Inc | Proteínas biológicas activas condicionalmente |
| CA3003399A1 (en) * | 2015-11-02 | 2017-05-11 | Bioatla, Llc | Conditionally active polypeptides |
| CN108780094B (zh) * | 2016-01-12 | 2022-09-13 | 生物蛋白有限公司 | 使用条件活性抗体的诊断方法 |
| WO2017180587A2 (en) | 2016-04-11 | 2017-10-19 | Obsidian Therapeutics, Inc. | Regulated biocircuit systems |
| MX2019002199A (es) * | 2016-08-31 | 2019-05-16 | Bioatla Llc | Polipeptidos condicionalmente activos y métodos para generarlos. |
| KR20250159733A (ko) | 2017-01-11 | 2025-11-11 | 브리스톨-마이어스 스큅 컴퍼니 | Psgl-1 길항제 및 그의 용도 |
| SG10202107808SA (en) | 2017-01-18 | 2021-08-30 | F1 Oncology Inc | Chimeric antigen receptors against axl or ror2 and methods of use thereof |
| PE20250933A1 (es) | 2017-03-14 | 2025-04-02 | Five Prime Therapeutics Inc | Anticuerpos de union a vista a ph acido |
| SG11202008593PA (en) | 2018-03-21 | 2020-10-29 | Five Prime Therapeutics Inc | ANTIBODIES BINDING TO VISTA AT ACIDIC pH |
| CN112513081A (zh) | 2018-06-14 | 2021-03-16 | 生物蛋白有限公司 | 多重特异性抗体构建体 |
| AU2019301120A1 (en) | 2018-07-11 | 2021-02-25 | Bristol-Myers Squibb Company | Antibodies binding to VISTA at acidic pH |
| CA3107161A1 (en) * | 2018-08-21 | 2020-02-27 | Bioatla, Inc. | Conditionally active proteins with ph selectivity |
| US12195544B2 (en) | 2018-09-21 | 2025-01-14 | Harpoon Therapeutics, Inc. | EGFR binding proteins and methods of use |
| JP7720785B2 (ja) | 2019-04-18 | 2025-08-08 | ブリストル－マイヤーズ スクイブ カンパニー | 低ｐＨで結合するために特異性が増強されたイピリムマブバリアント |
| WO2021257497A1 (en) * | 2020-06-15 | 2021-12-23 | Sarepta Therapeutis, Inc. | Adeno-associated virus antibodies and fragments thereof |
| IL298903A (en) * | 2020-06-18 | 2023-02-01 | Bioatla Llc | Antibodies against nectin-4 are conditionally active |
| CA3182384A1 (en) * | 2020-06-18 | 2021-12-23 | Jay M. Short | Conditionally active anti-cd46 antibodies, antibody fragments, their immunoconjugates and uses thereof |
| WO2023069892A1 (en) * | 2021-10-19 | 2023-04-27 | Short Jay M | Conditionally active proteins for neurodegenerative diseases |
| WO2024155457A2 (en) * | 2023-01-18 | 2024-07-25 | Harpoon Therapeutics, Inc. | Her2 targeting trispecific protein for treatment of cancer |
| KR20250155039A (ko) * | 2023-03-02 | 2025-10-29 | 바이오아트라, 인코퍼레이티드 | 조건부 활성 항-epcam 항체, 항체 단편 및 이를 포함하는 작제물 |
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| US20140206596A1 (en) * | 2013-01-18 | 2014-07-24 | University Of Southern California | Design of pH-Sensitive Oligopeptide Complexes For Drug Release Under Mildly Acidic Conditions |
| ES2913205T3 (es) | 2014-05-13 | 2022-06-01 | Bioatla Inc | Proteínas biológicas activas condicionalmente |
| CA3003399A1 (en) | 2015-11-02 | 2017-05-11 | Bioatla, Llc | Conditionally active polypeptides |
| MX2019002199A (es) * | 2016-08-31 | 2019-05-16 | Bioatla Llc | Polipeptidos condicionalmente activos y métodos para generarlos. |
-
2016
- 2016-08-31 CA CA3003399A patent/CA3003399A1/en active Pending
- 2016-08-31 US US15/773,122 patent/US11472876B2/en active Active
- 2016-08-31 RU RU2018115781A patent/RU2735023C9/ru active
- 2016-08-31 KR KR1020187014104A patent/KR102714709B1/ko active Active
- 2016-08-31 WO PCT/US2016/049715 patent/WO2017078839A1/en not_active Ceased
- 2016-08-31 CN CN202211275600.XA patent/CN115521374B/zh active Active
- 2016-08-31 EP EP16862643.0A patent/EP3371349A1/en active Pending
- 2016-08-31 AU AU2016350613A patent/AU2016350613B2/en active Active
- 2016-08-31 KR KR1020247032903A patent/KR20240150525A/ko active Pending
- 2016-08-31 MX MX2018005063A patent/MX2018005063A/es unknown
- 2016-08-31 JP JP2018522662A patent/JP7064769B2/ja active Active
- 2016-08-31 CN CN201680077540.7A patent/CN108473555B/zh active Active
-
2018
- 2018-04-24 MX MX2023001319A patent/MX2023001319A/es unknown
-
2022
- 2022-04-18 JP JP2022068158A patent/JP7390748B2/ja active Active
- 2022-08-19 US US17/820,913 patent/US20220403024A1/en active Pending
-
2023
- 2023-11-14 JP JP2023193435A patent/JP2024020382A/ja active Pending
- 2023-12-21 AU AU2023285915A patent/AU2023285915A1/en active Pending
-
2025
- 2025-11-04 JP JP2025185767A patent/JP2026027333A/ja active Pending
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