JP2018534114A5 - - Google Patents
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- JP2018534114A5 JP2018534114A5 JP2018545108A JP2018545108A JP2018534114A5 JP 2018534114 A5 JP2018534114 A5 JP 2018534114A5 JP 2018545108 A JP2018545108 A JP 2018545108A JP 2018545108 A JP2018545108 A JP 2018545108A JP 2018534114 A5 JP2018534114 A5 JP 2018534114A5
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- nucleic acid
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021131116A JP7239649B2 (ja) | 2015-11-13 | 2021-08-11 | 角膜ジストロフィーの治療方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562255310P | 2015-11-13 | 2015-11-13 | |
| US62/255,310 | 2015-11-13 | ||
| PCT/US2016/061893 WO2017083852A1 (en) | 2015-11-13 | 2016-11-14 | Methods for the treatment of corneal dystrophies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021131116A Division JP7239649B2 (ja) | 2015-11-13 | 2021-08-11 | 角膜ジストロフィーの治療方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018534114A JP2018534114A (ja) | 2018-11-22 |
| JP2018534114A5 true JP2018534114A5 (enExample) | 2019-12-19 |
| JP6929865B2 JP6929865B2 (ja) | 2021-09-01 |
Family
ID=58696178
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018545108A Expired - Fee Related JP6929865B2 (ja) | 2015-11-13 | 2016-11-14 | 角膜ジストロフィーの治療方法 |
| JP2021131116A Active JP7239649B2 (ja) | 2015-11-13 | 2021-08-11 | 角膜ジストロフィーの治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021131116A Active JP7239649B2 (ja) | 2015-11-13 | 2021-08-11 | 角膜ジストロフィーの治療方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11987809B2 (enExample) |
| EP (2) | EP3374502B1 (enExample) |
| JP (2) | JP6929865B2 (enExample) |
| KR (1) | KR20180120670A (enExample) |
| CN (1) | CN108699542A (enExample) |
| ES (1) | ES2905558T3 (enExample) |
| WO (1) | WO2017083852A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| KR102594051B1 (ko) * | 2016-08-20 | 2023-10-26 | 아벨리노 랩 유에스에이, 인크. | 단일 가이드 RNA, CRISPR/Cas9 시스템, 및 이의 사용방법 |
| EP3592381A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Cancer vaccine |
| CN110914310A (zh) | 2017-03-10 | 2020-03-24 | 哈佛大学的校长及成员们 | 胞嘧啶至鸟嘌呤碱基编辑器 |
| CA3065946A1 (en) * | 2017-06-05 | 2018-12-13 | Research Institute At Nationwide Children's Hospital | Enhanced modified viral capsid proteins |
| CN111065736A (zh) * | 2017-06-07 | 2020-04-24 | 国立大学法人东京大学 | 针对颗粒状角膜变性症的基因治疗药物 |
| US11732274B2 (en) | 2017-07-28 | 2023-08-22 | President And Fellows Of Harvard College | Methods and compositions for evolving base editors using phage-assisted continuous evolution (PACE) |
| US20190218532A1 (en) * | 2017-09-19 | 2019-07-18 | Massachusetts Institute Of Technology | Streptococcus Canis Cas9 as a Genome Engineering Platform with Novel PAM Specificity |
| SG11202002130WA (en) * | 2017-09-28 | 2020-04-29 | Toolgen Inc | Artificial genome manipulation for gene expression regulation |
| US11572574B2 (en) | 2017-09-28 | 2023-02-07 | Toolgen Incorporated | Artificial genome manipulation for gene expression regulation |
| EP3724332A1 (en) * | 2017-12-14 | 2020-10-21 | CRISPR Therapeutics AG | Novel rna-programmable endonuclease systems and their use in genome editing and other applications |
| WO2019118949A1 (en) | 2017-12-15 | 2019-06-20 | The Broad Institute, Inc. | Systems and methods for predicting repair outcomes in genetic engineering |
| EP3784249A4 (en) | 2018-04-25 | 2022-03-02 | Children's Medical Center Corporation | ABCB5 LIGANDS AND SUBSTRATES |
| WO2020092453A1 (en) | 2018-10-29 | 2020-05-07 | The Broad Institute, Inc. | Nucleobase editors comprising geocas9 and uses thereof |
| WO2020125762A1 (en) * | 2018-12-20 | 2020-06-25 | Peking University | Compositions and methods for highly efficient genetic screening using barcoded guide rna constructs |
| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| DE112020001342T5 (de) * | 2019-03-19 | 2022-01-13 | President and Fellows of Harvard College | Verfahren und Zusammensetzungen zum Editing von Nukleotidsequenzen |
| EP3946389A4 (en) * | 2019-03-28 | 2023-05-10 | Children's Medical Center Corporation | HIGH FUNCTIONAL ENGINEERED ABCB5+ MESENCHYMAL STEM CELLS |
| WO2020214842A1 (en) | 2019-04-17 | 2020-10-22 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| WO2021072328A1 (en) | 2019-10-10 | 2021-04-15 | The Broad Institute, Inc. | Methods and compositions for prime editing rna |
| JP2023503618A (ja) * | 2019-11-27 | 2023-01-31 | ザ ジェネラル ホスピタル コーポレイション | 遺伝子発現を活性化するためのシステムおよび方法 |
| RU2730975C1 (ru) * | 2020-02-18 | 2020-08-26 | Ирина Викторовна Булыгина | Способ лечения эндотелиально-эпителиальной дистрофии роговицы |
| WO2023004189A1 (en) * | 2021-07-23 | 2023-01-26 | Avellino Lab Usa, Inc. | Method for detecting alleles associated with keratoconus |
| CN116286823A (zh) * | 2023-04-04 | 2023-06-23 | 尧唐(上海)生物科技有限公司 | 靶向TGFBI基因的sgRNA、载体及其应用 |
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| US5049386A (en) | 1985-01-07 | 1991-09-17 | Syntex (U.S.A.) Inc. | N-ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)Alk-1-YL-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
| US4946787A (en) | 1985-01-07 | 1990-08-07 | Syntex (U.S.A.) Inc. | N-(ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
| US4897355A (en) | 1985-01-07 | 1990-01-30 | Syntex (U.S.A.) Inc. | N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US5925517A (en) | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| WO1997046714A1 (en) | 1996-06-04 | 1997-12-11 | University Of Utah Research Foundation | Monitoring hybridization during pcr |
| US6117635A (en) | 1996-07-16 | 2000-09-12 | Intergen Company | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
| US6018713A (en) | 1997-04-09 | 2000-01-25 | Coli; Robert D. | Integrated system and method for ordering and cumulative results reporting of medical tests |
| JP3380744B2 (ja) | 1998-05-19 | 2003-02-24 | 株式会社日立製作所 | センサおよびこれを利用した測定装置 |
| GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
| US6171112B1 (en) | 1998-09-18 | 2001-01-09 | Wyngate, Inc. | Methods and apparatus for authenticating informed consent |
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-
2016
- 2016-11-14 WO PCT/US2016/061893 patent/WO2017083852A1/en not_active Ceased
- 2016-11-14 EP EP16865232.9A patent/EP3374502B1/en active Active
- 2016-11-14 CN CN201680077123.2A patent/CN108699542A/zh active Pending
- 2016-11-14 EP EP21204643.7A patent/EP4036228A1/en not_active Withdrawn
- 2016-11-14 KR KR1020187016752A patent/KR20180120670A/ko not_active Ceased
- 2016-11-14 JP JP2018545108A patent/JP6929865B2/ja not_active Expired - Fee Related
- 2016-11-14 ES ES16865232T patent/ES2905558T3/es active Active
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2018
- 2018-05-11 US US15/977,565 patent/US11987809B2/en active Active
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2021
- 2021-08-11 JP JP2021131116A patent/JP7239649B2/ja active Active
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