JP2018532813A5 - - Google Patents
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- Publication number
- JP2018532813A5 JP2018532813A5 JP2018543291A JP2018543291A JP2018532813A5 JP 2018532813 A5 JP2018532813 A5 JP 2018532813A5 JP 2018543291 A JP2018543291 A JP 2018543291A JP 2018543291 A JP2018543291 A JP 2018543291A JP 2018532813 A5 JP2018532813 A5 JP 2018532813A5
- Authority
- JP
- Japan
- Prior art keywords
- vaccine according
- antigen
- vaccine
- protein
- chlamydia species
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 229960005486 vaccines Drugs 0.000 claims 24
- 239000000427 antigen Substances 0.000 claims 17
- 102000038129 antigens Human genes 0.000 claims 17
- 108091007172 antigens Proteins 0.000 claims 17
- 241000606161 Chlamydia Species 0.000 claims 10
- 102000004169 proteins and genes Human genes 0.000 claims 7
- 108090000623 proteins and genes Proteins 0.000 claims 7
- 150000001720 carbohydrates Chemical class 0.000 claims 6
- 235000014633 carbohydrates Nutrition 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 230000002458 infectious Effects 0.000 claims 3
- 230000003612 virological Effects 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 241000580858 Simian-Human immunodeficiency virus Species 0.000 claims 2
- 241001495184 Chlamydia sp. Species 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 201000009910 diseases by infectious agent Diseases 0.000 claims 1
- 230000002708 enhancing Effects 0.000 claims 1
- 102000014611 env Gene Products Human genes 0.000 claims 1
- 108010078428 env Gene Products Proteins 0.000 claims 1
- 230000004727 humoral immunity Effects 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 108060005683 ompA Proteins 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
Claims (22)
- 抗原と、クラミジア種のタンパク質、ペプチド、若しくは炭水化物、又はそれらの断片と、を含むワクチンであって、前記抗原がクラミジア種に由来しない、ワクチン。
- 前記クラミジア種が、C.トラコマチス、C.シッタシ、C.ムリダルム、又はC.ニューモニエを含む、請求項1に記載のワクチン。
- 前記クラミジア種が、不活性化される、請求項1又は2に記載のワクチン。
- 前記クラミジア種のタンパク質、ペプチド、若しくは炭水化物、又はそれらの断片が、クラミジアの主要外膜(MOMP)タンパク質を含む、請求項1〜3のいずれか一項に記載のワクチン。
- 前記ワクチンが、2つ以上の抗原を含む、請求項1〜4のいずれか一項に記載のワクチン。
- 前記ワクチンが、3つ以上の抗原を含む、請求項5に記載のワクチン。
- 前記抗原が、感染因子を含む、請求項1〜6のいずれか一項に記載のワクチン。
- 前記感染因子が、ウイルス性である、請求項7に記載のワクチン。
- 前記ウイルス性感染因子が、HIVである、請求項8に記載のワクチン。
- 前記抗原が、腫瘍関連抗原を含む、請求項1〜6のいずれか一項に記載のワクチン。
- 前記ワクチンが、前記抗原単独と比較して、特異的体液性免疫を高める、請求項1〜10のいずれか一項に記載のワクチン。
- 抗原と、クラミジア種のタンパク質、ペプチド、若しくは炭水化物、又はそれらの断片と、を含むキットであって、前記抗原がクラミジア種に由来しない、キット。
- 対象における疾患又は感染を予防又は治療するための、請求項1に記載のワクチン。
- 前記抗原が、ウイルス性である、請求項13に記載のワクチン。
- 前記抗原が、HIVに由来する、請求項14に記載のワクチン。
- 前記抗原が、envタンパク質、ペプチド、又はそれらの断片である、請求項15に記載のワクチン。
- 前記抗原が、腫瘍関連である、請求項13に記載のワクチン。
- 前記対象が、哺乳類である、請求項13〜17のいずれか一項に記載のワクチン。
- 前記哺乳類が、ヒトである、請求項18に記載のワクチン。
- 前記抗原と、前記クラミジア種のタンパク質、ペプチド、若しくは炭水化物、又はそれらの断片とが、同時に投与される、請求項13〜19のいずれか一項に記載のワクチン。
- 前記抗原が、前記クラミジア種のタンパク質、ペプチド、若しくは炭水化物、又はそれらの断片の前に投与される、請求項13〜19のいずれか一項に記載のワクチン。
- 前記抗原が、前記クラミジア種のタンパク質、ペプチド、若しくは炭水化物、又はそれらの断片の後に投与される、請求項13〜19のいずれか一項に記載のワクチン。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562253370P | 2015-11-10 | 2015-11-10 | |
US62/253,370 | 2015-11-10 | ||
PCT/US2016/061062 WO2017083337A1 (en) | 2015-11-10 | 2016-11-09 | Methods and compositions related to accelerated humoral affinity |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2018532813A JP2018532813A (ja) | 2018-11-08 |
JP2018532813A5 true JP2018532813A5 (ja) | 2019-12-19 |
JP7086000B2 JP7086000B2 (ja) | 2022-06-17 |
Family
ID=58695147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018543291A Active JP7086000B2 (ja) | 2015-11-10 | 2016-11-09 | 体液性親和性の加速に関する方法及び組成物 |
Country Status (7)
Country | Link |
---|---|
US (2) | US10835601B2 (ja) |
EP (1) | EP3373961A4 (ja) |
JP (1) | JP7086000B2 (ja) |
CN (1) | CN108367058A (ja) |
AU (2) | AU2016354444B2 (ja) |
CA (1) | CA3004924A1 (ja) |
WO (1) | WO2017083337A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP7146732B2 (ja) * | 2016-07-13 | 2022-10-04 | オハイオ ステート イノベーション ファウンデーション | 宿主抗原提示並びに宿主抗腫瘍及び抗病原体免疫を最適化するためのプラットフォーム及び方法 |
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WO1995012411A1 (en) * | 1993-11-03 | 1995-05-11 | Pfizer Inc. | Vaccine and method for treatment of chlamydial infections |
GB9626864D0 (en) | 1996-12-24 | 1997-02-12 | Smithkline Beecham Biolog | Vaccine |
US6001372A (en) | 1995-08-25 | 1999-12-14 | Wisconsin Alumni Research Foundation | Antigenic peptides of Chlamydia trachomatis |
WO1997026910A2 (de) | 1996-01-27 | 1997-07-31 | Max-Delbrück-Centrum für Molekulare Medizin | Tumorimpfstoff für die immuntherapie von malignen tumoren |
US6344202B1 (en) | 1996-07-12 | 2002-02-05 | University Of Manitoba | DNA immunization against chlaymdia infection |
US6465251B1 (en) | 1996-11-13 | 2002-10-15 | Dana-Farber Cancer Institute, Inc. | Method of promoting b-cell proliferation and activation with CD40 ligand and cyclosporin |
CA2216559A1 (en) | 1997-09-25 | 1999-03-25 | Michel Roberge | G2 checkpoint inhibitors and assay |
US7041490B1 (en) | 1997-11-28 | 2006-05-09 | Serono Genetics Institute, S.A. | Chlamydia trachomatis polynucleotides and vectors, recombinant host cells, DNA chips or kits containing the same |
EP2172214A3 (en) | 1999-03-12 | 2011-03-16 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
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WO2001034194A1 (en) | 1999-11-08 | 2001-05-17 | Idec Pharmaceuticals Corporation | Treatment of b cell malignancies using anti-cd40l antibodies in combination with anti-cd20 antibodies and/or chemotherapeutics and radiotherapy |
DE19954514A1 (de) | 1999-11-12 | 2001-05-17 | Schoellhorn Volkmar | Verfahren zur Manipulation der Aktivität von Zellen |
WO2001056603A1 (en) | 2000-02-01 | 2001-08-09 | Tanox, Inc. | Cd40-binding apc-activating molecules |
ATE321870T1 (de) | 2000-06-05 | 2006-04-15 | Corixa Corp | Leader-anteile zur erhöhung der sekretion von rekombinanten proteine aus einer wirtzelle |
AU2001276619A1 (en) * | 2000-07-03 | 2002-01-14 | Chiron S.P.A. | Immunisation against chlamydia pneumoniae |
GB0103170D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
US7537772B1 (en) | 2000-10-02 | 2009-05-26 | Emergent Product Development Gaithersburg Inc. | Chlamydia protein, gene sequence and the uses thereof |
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EP1465657A4 (en) | 2001-12-18 | 2006-02-01 | Health Research Inc | METHOD FOR INCREASING IMMUNOGENICITY BY COVALENT COMPOUNDS OF ANTIGENS WITH PROTEINS ON THE SURFACE OF DENDRITIC CELLS |
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GB0220194D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
DE10326187A1 (de) * | 2003-06-06 | 2005-01-05 | MedInnova Gesellschaft für medizinische Innovationen aus akademischer Forschung mbH | Zellen als Träger für Bakterien |
US7368537B2 (en) | 2003-07-15 | 2008-05-06 | Id Biomedical Corporation Of Quebec | Subunit vaccine against respiratory syncytial virus infection |
US20060121055A1 (en) * | 2004-12-06 | 2006-06-08 | Becton, Dickinson And Company, Inc. | Compositions with enhanced immunogenicity |
JP2008534594A (ja) | 2005-03-31 | 2008-08-28 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | クラミジア感染に対するワクチン |
US8318906B2 (en) | 2005-04-15 | 2012-11-27 | The Regents Of The University Of California | EMP2 antibodies and their therapeutic uses |
US7964200B2 (en) | 2005-05-18 | 2011-06-21 | Children's Hospital & Research Center At Oakland | Methods and compositions for immunizing against Chlamydia infection |
WO2006128296A1 (en) | 2005-06-01 | 2006-12-07 | Sanofi Pasteur Limited | Pal-based chlamydia vaccine |
WO2007012944A2 (en) | 2005-07-28 | 2007-02-01 | Pfizer Products Inc. | Methods of vaccine administration, new feline caliciviruses, and treatments for immunizing animals against feline paraovirus and feline herpes virus |
EP1976557A2 (en) * | 2005-12-22 | 2008-10-08 | Novartis Vaccines and Diagnostics S.r.l. | Chlamydial antigens |
ES2529257T3 (es) | 2006-04-27 | 2015-02-18 | Cellid Co., Ltd | Vacuna basada en células B cargadas con el ligando de células T asesinas naturales y antígeno |
US20140056967A1 (en) | 2007-09-28 | 2014-02-27 | Glaxosmithkline Biologicals S.A. | Vaccines against chlamydial infection |
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JP5824870B2 (ja) | 2011-05-25 | 2015-12-02 | 株式会社リコー | 画像形成装置 |
BR112014007927B1 (pt) | 2011-10-06 | 2021-04-13 | Immunovaccine Technologies Inc | Composições de lipossoma compreendendo um adjuvante e usos das referidas composições e usos das referidas composições |
ES2762631T3 (es) | 2013-03-14 | 2020-05-25 | Harvard College | Composiciones a base de nanopartículas |
PL2976355T3 (pl) | 2013-03-18 | 2020-07-13 | Statens Serum Institut | Szczepionki przeciwko Chlamydia sp. |
EP3027210A1 (en) | 2013-08-02 | 2016-06-08 | Aduro Biotech Holdings, Europe B.V. | Combining cd27 agonists and immune checkpoint inhibition for immune stimulation |
ES2900757T3 (es) | 2015-02-10 | 2022-03-18 | Ohio State Innovation Foundation | Plataformas de células B activadas por clamidia y procedimientos de las mismas |
-
2016
- 2016-11-09 CA CA3004924A patent/CA3004924A1/en not_active Abandoned
- 2016-11-09 JP JP2018543291A patent/JP7086000B2/ja active Active
- 2016-11-09 WO PCT/US2016/061062 patent/WO2017083337A1/en active Application Filing
- 2016-11-09 AU AU2016354444A patent/AU2016354444B2/en active Active
- 2016-11-09 CN CN201680072156.8A patent/CN108367058A/zh active Pending
- 2016-11-09 US US15/775,155 patent/US10835601B2/en active Active
- 2016-11-09 EP EP16864881.4A patent/EP3373961A4/en active Pending
-
2020
- 2020-09-30 US US17/038,423 patent/US20210015914A1/en not_active Abandoned
-
2021
- 2021-07-01 AU AU2021204628A patent/AU2021204628B2/en active Active
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