JP2013523783A5 - - Google Patents
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- Publication number
- JP2013523783A5 JP2013523783A5 JP2013502959A JP2013502959A JP2013523783A5 JP 2013523783 A5 JP2013523783 A5 JP 2013523783A5 JP 2013502959 A JP2013502959 A JP 2013502959A JP 2013502959 A JP2013502959 A JP 2013502959A JP 2013523783 A5 JP2013523783 A5 JP 2013523783A5
- Authority
- JP
- Japan
- Prior art keywords
- hiv
- fragment
- env
- protein
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000725303 Human immunodeficiency virus Species 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 9
- 230000000521 hyperimmunizing Effects 0.000 claims 6
- 102000014611 env Gene Products Human genes 0.000 claims 5
- 108010078428 env Gene Products Proteins 0.000 claims 5
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 210000003022 Colostrum Anatomy 0.000 claims 4
- 235000021277 colostrum Nutrition 0.000 claims 4
- 230000005540 biological transmission Effects 0.000 claims 3
- 230000003053 immunization Effects 0.000 claims 3
- 210000004779 membrane envelope Anatomy 0.000 claims 3
- 108091008117 polyclonal antibodies Proteins 0.000 claims 3
- 210000004080 Milk Anatomy 0.000 claims 2
- 230000002458 infectious Effects 0.000 claims 2
- 235000013336 milk Nutrition 0.000 claims 2
- 239000008267 milk Substances 0.000 claims 2
- 230000001629 suppression Effects 0.000 claims 2
- 238000002255 vaccination Methods 0.000 claims 1
Claims (10)
- ヒト免疫不全ウイルス（ＨＩＶ）ウイルスエンベロープ（Ｅｎｖ）タンパク質又はそのフラグメントに結合することができるポリクローナル抗体又はそのフラグメントを含む、ＨＩＶの伝染を抑制する組成物。
- 前記Ｅｎｖタンパク質又はそのフラグメントがｇｐ１４０である、請求項１記載の組成物。
- 前記Ｅｎｖタンパク質又はそのフラグメントがｇｐ１４０オリゴマーである、請求項１又は請求項２記載の組成物。
- 前記ポリクローナル抗体又はそのフラグメントが、ＨＩＶの異種クレードのＥｎｖタンパク質に結合することができる、請求項１〜３のいずれか１項記載の組成物。
- 動物をＨＩＶウイルスエンベロープ（Ｅｎｖ）タンパク質又はそのフラグメントで免疫化すること及び免疫化された動物から高度免疫初乳を得ることを含む、ＨＩＶの伝染を抑制する組成物を調製する方法。
- 動物をＨＩＶウイルスエンベロープ（Ｅｎｖ）タンパク質又はそのフラグメントで免疫化すること及び免疫化された動物から高度免疫初乳を得ることを含む方法により調製される、ＨＩＶの伝染を抑制する組成物。
- ＨＩＶの伝染を抑制する組成物を調製する方法であって、
被験者に投与されることになる高度免疫初乳又は高度免疫乳汁を、雌ウシを免疫化することによって形成することを含み、ここで雌ウシを免疫化して高度免疫初乳又は高度免疫乳汁を形成する工程が、ヒト免疫不全ウイルス（ＨＩＶ）ウイルスエンベロープ（Ｅｎｖ）タンパク質又はそのフラグメントによるワクチン接種を含む、方法。 - 前記Ｅｎｖタンパク質又はそのフラグメントがｇｐ１４０である、請求項７記載の方法。
- ヒト免疫不全ウイルス（ＨＩＶ）ウイルスエンベロープ（Ｅｎｖ）タンパク質又はそのフラグメントに結合することができるポリクローナル抗体又はそのフラグメントを含み、被験者に投与されるように用いられるＨＩＶの伝染を抑制する組成物。
- 前記Ｅｎｖタンパク質又はそのフラグメントがｇｐ１４０である、請求項９記載の組成物。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32239910P | 2010-04-09 | 2010-04-09 | |
| US61/322,399 | 2010-04-09 | ||
| PCT/AU2011/000407 WO2011123900A1 (en) | 2010-04-09 | 2011-04-11 | Methods and compositions for inhibiting hiv transmission |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013523783A JP2013523783A (ja) | 2013-06-17 |
| JP2013523783A5 true JP2013523783A5 (ja) | 2014-05-29 |
| JP6026402B2 JP6026402B2 (ja) | 2016-11-16 |
Family
ID=44761932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013502959A Expired - Fee Related JP6026402B2 (ja) | 2010-04-09 | 2011-04-11 | Ｈｉｖの伝染を抑制する方法及び組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20130022619A1 (ja) |
| EP (1) | EP2555798B1 (ja) |
| JP (1) | JP6026402B2 (ja) |
| CN (1) | CN103167881B (ja) |
| AP (1) | AP3469A (ja) |
| AU (2) | AU2011238431B2 (ja) |
| BR (1) | BR112012025678A2 (ja) |
| CA (1) | CA2795853A1 (ja) |
| MX (1) | MX343505B (ja) |
| RU (1) | RU2594249C2 (ja) |
| WO (1) | WO2011123900A1 (ja) |
| ZA (1) | ZA201207790B (ja) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3049524A4 (en) * | 2013-09-27 | 2017-06-14 | Duke University | Hiv-1 mother-to-child transmission correlates of protection and vaccine |
| CN103736100B (zh) * | 2013-12-25 | 2017-06-09 | 南方医科大学 | 预防hiv性传播的杀微生物剂酸酐修饰抗sevi多克隆抗体 |
| EP3662930A1 (en) * | 2015-09-24 | 2020-06-10 | AbVitro LLC | Hiv antibody compositions and methods of use |
| WO2017062070A1 (en) * | 2015-10-07 | 2017-04-13 | Eca Medical Instruments | Gearless compact torque drive |
| US10973679B2 (en) * | 2016-02-12 | 2021-04-13 | Adam Arreola | STD detecting condom |
| CN116171165A (zh) * | 2020-06-10 | 2023-05-26 | 墨尔本大学 | Hiv-1抗体 |
| IL308087A (en) | 2021-05-12 | 2023-12-01 | Applied Biomedical Science Inst | Methods for the screening and expression of disulfide-bonded polypeptides |
| WO2022241057A1 (en) | 2021-05-12 | 2022-11-17 | Applied Biomedical Science Institute | Binding polypeptides against sars cov-2 and uses thereof |
| JP7421610B1 (ja) | 2022-08-18 | 2024-01-24 | 株式会社マーベラス | ゲーム装置 |
| WO2024108050A1 (en) | 2022-11-16 | 2024-05-23 | Applied Biomedical Science Institute | Fusion polypeptides and binding peptides and methods for producing and using same |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6039957A (en) * | 1993-12-10 | 2000-03-21 | United States Of America, As Represented By The Department Of Health And Human Services | Oligomeric HIV-1 envelope glycoproteins |
| AU777241B2 (en) * | 1999-06-24 | 2004-10-07 | Johns Hopkins University, The | Compositions and methods for preventing transepithelial transmission of HIV |
| US6753015B2 (en) * | 2000-09-28 | 2004-06-22 | Chiron Corporation | Microparticle compositions and methods for the manufacture thereof |
| WO2008063331A2 (en) * | 2006-10-23 | 2008-05-29 | Progenics Pharmaceuticals, Inc. | Modified gp140 envelope polypeptides of hiv-1 isolates, compositions, stabilized trimeric complexes, and uses thereof |
| CA2704059A1 (en) * | 2007-10-30 | 2009-05-07 | International Aids Vaccine Initiative | Antigen-antibody complexes as hiv-1 vaccines |
| CA2739905A1 (en) * | 2008-10-30 | 2010-08-26 | Dana-Farber Cancer Institute | Mimotopes of hiv env |
-
2011
- 2011-04-11 CN CN201180028300.5A patent/CN103167881B/zh not_active Expired - Fee Related
- 2011-04-11 MX MX2012011574A patent/MX343505B/es active IP Right Grant
- 2011-04-11 AU AU2011238431A patent/AU2011238431B2/en not_active Ceased
- 2011-04-11 US US13/639,831 patent/US20130022619A1/en not_active Abandoned
- 2011-04-11 WO PCT/AU2011/000407 patent/WO2011123900A1/en active Application Filing
- 2011-04-11 AP AP2012006519A patent/AP3469A/xx active
- 2011-04-11 EP EP11764957.4A patent/EP2555798B1/en not_active Not-in-force
- 2011-04-11 RU RU2012142999/15A patent/RU2594249C2/ru not_active IP Right Cessation
- 2011-04-11 JP JP2013502959A patent/JP6026402B2/ja not_active Expired - Fee Related
- 2011-04-11 BR BR112012025678A patent/BR112012025678A2/pt not_active Application Discontinuation
- 2011-04-11 CA CA2795853A patent/CA2795853A1/en not_active Abandoned
-
2012
- 2012-10-17 ZA ZA2012/07790A patent/ZA201207790B/en unknown
-
2017
- 2017-11-22 AU AU2017265055A patent/AU2017265055A1/en not_active Abandoned
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