JP2018531288A5 - - Google Patents

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Publication number
JP2018531288A5
JP2018531288A5 JP2018540217A JP2018540217A JP2018531288A5 JP 2018531288 A5 JP2018531288 A5 JP 2018531288A5 JP 2018540217 A JP2018540217 A JP 2018540217A JP 2018540217 A JP2018540217 A JP 2018540217A JP 2018531288 A5 JP2018531288 A5 JP 2018531288A5
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JP
Japan
Prior art keywords
methylamino
pyrrolidin
pyrimidine
diamine
cyclopropylmethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018540217A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018531288A6 (ja
JP2018531288A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2016/075708 external-priority patent/WO2017072131A1/en
Publication of JP2018531288A publication Critical patent/JP2018531288A/ja
Publication of JP2018531288A6 publication Critical patent/JP2018531288A6/ja
Publication of JP2018531288A5 publication Critical patent/JP2018531288A5/ja
Pending legal-status Critical Current

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JP2018540217A 2015-10-26 2016-10-25 ピリミジン組成物、超高純度組成物およびその塩、それを作成する方法、ならびにヒスタミンh4受容体(h4)によって媒介される疾患および状態を治療するためにそれを用いる方法 Pending JP2018531288A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562246482P 2015-10-26 2015-10-26
US62/246,482 2015-10-26
US201662329091P 2016-04-28 2016-04-28
US62/329,091 2016-04-28
US201662359066P 2016-07-06 2016-07-06
US62/359,066 2016-07-06
PCT/EP2016/075708 WO2017072131A1 (en) 2015-10-26 2016-10-25 Pyrimidine compositions, ultra-pure compositions and salts thereof, methods of making the same, and methods of using the same for treating histamine h4 receptor (h4) mediated diseases and conditions

Publications (3)

Publication Number Publication Date
JP2018531288A JP2018531288A (ja) 2018-10-25
JP2018531288A6 JP2018531288A6 (ja) 2018-12-13
JP2018531288A5 true JP2018531288A5 (https=) 2019-12-05

Family

ID=57200025

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018540217A Pending JP2018531288A (ja) 2015-10-26 2016-10-25 ピリミジン組成物、超高純度組成物およびその塩、それを作成する方法、ならびにヒスタミンh4受容体(h4)によって媒介される疾患および状態を治療するためにそれを用いる方法

Country Status (21)

Country Link
US (2) US20170158671A1 (https=)
EP (1) EP3368528A1 (https=)
JP (1) JP2018531288A (https=)
KR (1) KR20180067683A (https=)
CN (1) CN108602801A (https=)
AU (2) AU2016344627B9 (https=)
BR (1) BR112018007765A2 (https=)
CA (1) CA3001636A1 (https=)
CL (1) CL2018001092A1 (https=)
CO (1) CO2018004323A2 (https=)
EC (1) ECSP18038867A (https=)
HK (1) HK1252050A1 (https=)
IL (1) IL258813A (https=)
MX (1) MX2018005140A (https=)
PE (1) PE20181364A1 (https=)
PH (1) PH12018500822A1 (https=)
RU (1) RU2018119104A (https=)
SG (1) SG11201802676QA (https=)
TW (1) TW201729810A (https=)
WO (1) WO2017072131A1 (https=)
ZA (1) ZA201802183B (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
WO2015105955A1 (en) 2014-01-08 2015-07-16 Flodesign Sonics, Inc. Acoustophoresis device with dual acoustophoretic chamber
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
WO2018156180A1 (en) 2017-02-24 2018-08-30 Kindred Biosciences, Inc. Anti-il31 antibodies for veterinary use
RU2020111694A (ru) * 2017-10-09 2021-11-12 Тева Фармасьютикал Индастриз Лтд. Новые соли и твердые формы эсциталопрама
WO2019118921A1 (en) 2017-12-14 2019-06-20 Flodesign Sonics, Inc. Acoustic transducer drive and controller
JP2024506384A (ja) 2021-02-10 2024-02-13 イオリクス セラピューティクス,インコーポレーテッド ロフルミラストの眼科的送達方法
CA3231766A1 (en) 2021-09-22 2023-03-30 Elizabeth W. JEFFORDS Methods of treating ocular inflammatory diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002072548A2 (en) 2001-03-09 2002-09-19 Ortho-Mcneil Pharmaceutical, Inc. Heterocyclic compounds and their use as histamine h4 ligands.
EP1543011B1 (en) 2002-09-06 2006-05-03 Janssen Pharmaceutica N.V. Thienopyrrolyl and furanopyrrolyl compounds and their use as histamine h4 receptor ligands
KR101235116B1 (ko) * 2005-10-17 2013-02-20 에스케이케미칼주식회사 광학활성 암로디핀 겐티세이트 염의 제조방법
NL2000323C2 (nl) 2005-12-20 2007-11-20 Pfizer Ltd Pyrimidine-derivaten.
JP2008127359A (ja) * 2006-11-22 2008-06-05 Kowa Co アトピー性皮膚炎の予防及び/又は治療剤
EP3378476A1 (en) * 2012-06-08 2018-09-26 Sensorion H4 receptor inhibitors for treating tinnitus

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