JP2018529331A5 - - Google Patents
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- Publication number
- JP2018529331A5 JP2018529331A5 JP2018511416A JP2018511416A JP2018529331A5 JP 2018529331 A5 JP2018529331 A5 JP 2018529331A5 JP 2018511416 A JP2018511416 A JP 2018511416A JP 2018511416 A JP2018511416 A JP 2018511416A JP 2018529331 A5 JP2018529331 A5 JP 2018529331A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- amino acid
- mutation
- seq
- acid residue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562213466P | 2015-09-02 | 2015-09-02 | |
| US62/213,466 | 2015-09-02 | ||
| PCT/EP2016/070654 WO2017037196A1 (en) | 2015-09-02 | 2016-09-01 | Stabilized viral class i fusion proteins |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020188363A Division JP2021045138A (ja) | 2015-09-02 | 2020-11-12 | 安定化したウイルスクラスｉ融合タンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018529331A JP2018529331A (ja) | 2018-10-11 |
| JP2018529331A5 true JP2018529331A5 (enExample) | 2019-08-08 |
| JP6975709B2 JP6975709B2 (ja) | 2021-12-01 |
Family
ID=56855456
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018511416A Active JP6975709B2 (ja) | 2015-09-02 | 2016-09-01 | 安定化したウイルスクラスｉ融合タンパク質 |
| JP2020188363A Pending JP2021045138A (ja) | 2015-09-02 | 2020-11-12 | 安定化したウイルスクラスｉ融合タンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020188363A Pending JP2021045138A (ja) | 2015-09-02 | 2020-11-12 | 安定化したウイルスクラスｉ融合タンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10538557B2 (enExample) |
| EP (2) | EP4019044A3 (enExample) |
| JP (2) | JP6975709B2 (enExample) |
| CN (1) | CN108025057B (enExample) |
| AU (2) | AU2016316723B2 (enExample) |
| CA (1) | CA2997181A1 (enExample) |
| WO (1) | WO2017037196A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL257800B2 (en) | 2015-09-03 | 2023-11-01 | Novavax Inc | Immune compositions with improved stability and immunogenicity |
| EP4599847A3 (en) | 2016-10-25 | 2025-11-12 | Trustees of Dartmouth College | Prefusion coronavirus spike proteins and their use |
| US12083228B2 (en) | 2017-07-24 | 2024-09-10 | Novavax, Inc. | Methods and compositions for treating respiratory disease |
| AU2019238171B2 (en) | 2018-03-19 | 2026-01-08 | Novavax, Inc. | Multivalent influenza nanoparticle vaccines |
| EP3836961A1 (en) | 2018-08-13 | 2021-06-23 | Janssen Vaccines & Prevention B.V. | Stabilized filovirus glycoprotein trimers |
| CN109142723B (zh) * | 2018-08-21 | 2021-07-13 | 苏州华益美生物科技有限公司 | 人类免疫缺陷病毒快速检测测试卡及其应用 |
| US10953089B1 (en) | 2020-01-27 | 2021-03-23 | Novavax, Inc. | Coronavirus vaccine formulations |
| KR20230009489A (ko) | 2020-05-11 | 2023-01-17 | 얀센 파마슈티칼즈, 인코포레이티드 | 안정화된 코로나 바이러스 스파이크 단백질을 암호화하는 rna 레플리콘 |
| AU2021269783A1 (en) | 2020-05-11 | 2022-12-08 | Janssen Pharmaceuticals, Inc. | Stabilized coronavirus spike protein fusion proteins |
| MX2022014161A (es) | 2020-05-11 | 2022-12-02 | Janssen Pharmaceuticals Inc | Vacunas contra sars-cov-2. |
| CA3180554A1 (en) * | 2020-05-29 | 2021-12-02 | Jason MCLELLAN | Engineered coronavirus spike (s) protein and methods of use thereof |
| CN111704657B (zh) * | 2020-06-16 | 2021-11-09 | 四川安可瑞新材料技术有限公司 | Hiv-2重组抗原及其制备方法、用途 |
| KR20230035340A (ko) | 2020-07-06 | 2023-03-13 | 얀센 파마슈티칼즈, 인코포레이티드 | 안정화된 코로나 바이러스 스파이크 단백질 융합 단백질 |
| WO2022032274A1 (en) * | 2020-08-02 | 2022-02-10 | Richard Ascione | Vaccine compositions for influenza viruses and methods of use |
| EP4314018A4 (en) * | 2021-03-30 | 2025-04-30 | Baylor College of Medicine | Polypeptide-based protein inhibition methods and compositions with high sweetness |
| WO2023047348A1 (en) | 2021-09-24 | 2023-03-30 | Janssen Pharmaceuticals, Inc. | Stabilized corona virus spike protein fusion proteins |
| WO2023047349A1 (en) | 2021-09-24 | 2023-03-30 | Janssen Pharmaceuticals, Inc. | Stabilized coronavirus spike protein fusion proteins |
| US12616747B2 (en) | 2021-12-03 | 2026-05-05 | Board Of Regents, The University Of Texas System | Stabilized beta-coronavirus antigens |
| WO2024061759A1 (en) | 2022-09-23 | 2024-03-28 | Janssen Vaccines & Prevention B.V. | Stabilized coronavirus s proteins |
| CN116947982B (zh) * | 2023-07-12 | 2024-05-14 | 吉林大学 | 三条优势表位肽序列及其在流感病毒疫苗的应用 |
| WO2025051975A1 (en) * | 2023-09-06 | 2025-03-13 | Sanofi | Modified influenza b hemagglutinin polypeptides and nucleic acids and uses thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3584341D1 (de) | 1984-08-24 | 1991-11-14 | Upjohn Co | Rekombinante dna-verbindungen und expression von polypeptiden wie tpa. |
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| NZ230747A (en) | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
| WO1990014837A1 (en) | 1989-05-25 | 1990-12-13 | Chiron Corporation | Adjuvant formulation comprising a submicron oil droplet emulsion |
| US5786464C1 (en) | 1994-09-19 | 2012-04-24 | Gen Hospital Corp | Overexpression of mammalian and viral proteins |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| SE0202110D0 (sv) | 2002-07-05 | 2002-07-05 | Isconova Ab | Iscom preparation and use thereof |
| SE0301998D0 (sv) | 2003-07-07 | 2003-07-07 | Isconova Ab | Quil A fraction with low toxicity and use thereof |
| HUE042053T2 (hu) * | 2008-06-05 | 2019-06-28 | Ablynx Nv | Vírus burokfehérjéi elleni aminosav-szekvenciák és az azokat tartalmazó polipeptidek virális betegségek kezelésére |
| CN103842374A (zh) * | 2011-05-13 | 2014-06-04 | 诺华股份有限公司 | 融合前的rsv f抗原 |
| SG10201602434UA (en) * | 2011-09-30 | 2016-05-30 | Novavax Inc | Recombinant nanoparticle rsv f vaccine for respiratory syncytial virus |
| AU2012343981B2 (en) * | 2011-11-28 | 2017-09-07 | Janssen Vaccines & Prevention B.V. | Influenza virus vaccines and uses thereof |
| AU2014259474B2 (en) * | 2013-04-25 | 2018-09-13 | Janssen Vaccines & Prevention B.V. | Stabilized soluble prefusion RSV F polypeptides |
| EP2873423B1 (en) * | 2013-10-07 | 2017-05-31 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| US9931394B2 (en) * | 2015-03-23 | 2018-04-03 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
-
2016
- 2016-09-01 CA CA2997181A patent/CA2997181A1/en active Pending
- 2016-09-01 EP EP21200796.7A patent/EP4019044A3/en not_active Withdrawn
- 2016-09-01 JP JP2018511416A patent/JP6975709B2/ja active Active
- 2016-09-01 WO PCT/EP2016/070654 patent/WO2017037196A1/en not_active Ceased
- 2016-09-01 AU AU2016316723A patent/AU2016316723B2/en active Active
- 2016-09-01 EP EP16760463.6A patent/EP3344288A1/en not_active Withdrawn
- 2016-09-01 US US15/756,800 patent/US10538557B2/en active Active
- 2016-09-01 CN CN201680051120.1A patent/CN108025057B/zh active Active
-
2019
- 2019-12-03 US US16/701,429 patent/US10711042B2/en active Active
-
2020
- 2020-11-12 JP JP2020188363A patent/JP2021045138A/ja active Pending
-
2021
- 2021-03-02 AU AU2021201330A patent/AU2021201330A1/en not_active Abandoned
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