JP2018528417A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018528417A5 JP2018528417A5 JP2018505669A JP2018505669A JP2018528417A5 JP 2018528417 A5 JP2018528417 A5 JP 2018528417A5 JP 2018505669 A JP2018505669 A JP 2018505669A JP 2018505669 A JP2018505669 A JP 2018505669A JP 2018528417 A5 JP2018528417 A5 JP 2018528417A5
- Authority
- JP
- Japan
- Prior art keywords
- analyte
- detection conjugate
- detection
- sample
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims description 58
- 238000001514 detection method Methods 0.000 claims description 49
- 239000012491 analyte Substances 0.000 claims description 39
- 229910052751 metal Inorganic materials 0.000 claims description 31
- 239000002184 metal Substances 0.000 claims description 31
- 239000002086 nanomaterial Substances 0.000 claims description 27
- 239000000427 antigen Substances 0.000 claims description 23
- 108091007433 antigens Proteins 0.000 claims description 23
- 102000036639 antigens Human genes 0.000 claims description 23
- 239000002131 composite material Substances 0.000 claims description 15
- 230000003287 optical effect Effects 0.000 claims description 12
- 150000004676 glycans Chemical class 0.000 claims description 9
- 229920001282 polysaccharide Polymers 0.000 claims description 9
- 239000005017 polysaccharide Substances 0.000 claims description 9
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical group [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 8
- 230000001717 pathogenic effect Effects 0.000 claims description 8
- 229920002774 Maltodextrin Polymers 0.000 claims description 7
- 239000005913 Maltodextrin Substances 0.000 claims description 7
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 7
- 229940035034 maltodextrin Drugs 0.000 claims description 7
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims description 6
- 239000002202 Polyethylene glycol Substances 0.000 claims description 6
- 239000002981 blocking agent Substances 0.000 claims description 6
- 229940098773 bovine serum albumin Drugs 0.000 claims description 6
- 239000011248 coating agent Substances 0.000 claims description 6
- 238000000576 coating method Methods 0.000 claims description 6
- 239000002105 nanoparticle Substances 0.000 claims description 6
- 229920001223 polyethylene glycol Polymers 0.000 claims description 6
- 239000011541 reaction mixture Substances 0.000 claims description 6
- 229910052709 silver Inorganic materials 0.000 claims description 6
- 239000004332 silver Substances 0.000 claims description 6
- 238000001228 spectrum Methods 0.000 claims description 6
- 241000606701 Rickettsia Species 0.000 claims description 5
- 229920001222 biopolymer Polymers 0.000 claims description 5
- 229910052737 gold Inorganic materials 0.000 claims description 5
- 239000010931 gold Substances 0.000 claims description 5
- 241000606646 Anaplasma Species 0.000 claims description 4
- 241000589968 Borrelia Species 0.000 claims description 4
- 208000016604 Lyme disease Diseases 0.000 claims description 4
- 230000001580 bacterial effect Effects 0.000 claims description 4
- 238000002329 infrared spectrum Methods 0.000 claims description 4
- 230000003595 spectral effect Effects 0.000 claims description 4
- 230000003612 virological effect Effects 0.000 claims description 4
- 241000193738 Bacillus anthracis Species 0.000 claims description 3
- 241000282465 Canis Species 0.000 claims description 3
- 241001138501 Salmonella enterica Species 0.000 claims description 3
- 229940065181 bacillus anthracis Drugs 0.000 claims description 3
- 230000002538 fungal effect Effects 0.000 claims description 3
- -1 nanostars Substances 0.000 claims description 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 3
- 241000605281 Anaplasma phagocytophilum Species 0.000 claims description 2
- 108091023037 Aptamer Proteins 0.000 claims description 2
- 241000193830 Bacillus <bacterium> Species 0.000 claims description 2
- 108010076119 Caseins Proteins 0.000 claims description 2
- 108010010803 Gelatin Proteins 0.000 claims description 2
- 108010015899 Glycopeptides Proteins 0.000 claims description 2
- 102000002068 Glycopeptides Human genes 0.000 claims description 2
- 108090001030 Lipoproteins Proteins 0.000 claims description 2
- 102000004895 Lipoproteins Human genes 0.000 claims description 2
- 102000011931 Nucleoproteins Human genes 0.000 claims description 2
- 108010061100 Nucleoproteins Proteins 0.000 claims description 2
- 108010058846 Ovalbumin Proteins 0.000 claims description 2
- 241000607142 Salmonella Species 0.000 claims description 2
- 240000008042 Zea mays Species 0.000 claims description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 2
- 238000000862 absorption spectrum Methods 0.000 claims description 2
- 239000000956 alloy Substances 0.000 claims description 2
- 229910045601 alloy Inorganic materials 0.000 claims description 2
- 239000005018 casein Substances 0.000 claims description 2
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims description 2
- 235000021240 caseins Nutrition 0.000 claims description 2
- 235000005822 corn Nutrition 0.000 claims description 2
- 238000000295 emission spectrum Methods 0.000 claims description 2
- 239000002158 endotoxin Substances 0.000 claims description 2
- 239000000835 fiber Substances 0.000 claims description 2
- 239000012634 fragment Substances 0.000 claims description 2
- 108010074605 gamma-Globulins Proteins 0.000 claims description 2
- 239000000499 gel Substances 0.000 claims description 2
- 239000008273 gelatin Substances 0.000 claims description 2
- 229920000159 gelatin Polymers 0.000 claims description 2
- 235000019322 gelatine Nutrition 0.000 claims description 2
- 235000011852 gelatine desserts Nutrition 0.000 claims description 2
- 239000003446 ligand Substances 0.000 claims description 2
- 229920006008 lipopolysaccharide Polymers 0.000 claims description 2
- 239000002073 nanorod Substances 0.000 claims description 2
- 239000002078 nanoshell Substances 0.000 claims description 2
- 239000002071 nanotube Substances 0.000 claims description 2
- 239000002070 nanowire Substances 0.000 claims description 2
- 229940092253 ovalbumin Drugs 0.000 claims description 2
- 108091033319 polynucleotide Proteins 0.000 claims description 2
- 102000040430 polynucleotide Human genes 0.000 claims description 2
- 239000002157 polynucleotide Substances 0.000 claims description 2
- 229920001184 polypeptide Polymers 0.000 claims description 2
- 239000006188 syrup Substances 0.000 claims description 2
- 235000020357 syrup Nutrition 0.000 claims description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 241000605314 Ehrlichia Species 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- TVEXGJYMHHTVKP-UHFFFAOYSA-N 6-oxabicyclo[3.2.1]oct-3-en-7-one Chemical compound C1C2C(=O)OC1C=CC2 TVEXGJYMHHTVKP-UHFFFAOYSA-N 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 241000589969 Borreliella burgdorferi Species 0.000 claims 1
- 206010057249 Phagocytosis Diseases 0.000 claims 1
- 241000606695 Rickettsia rickettsii Species 0.000 claims 1
- 241000276425 Xiphophorus maculatus Species 0.000 claims 1
- 230000008782 phagocytosis Effects 0.000 claims 1
- 229940075118 rickettsia rickettsii Drugs 0.000 claims 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 6
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 3
- 229960005070 ascorbic acid Drugs 0.000 description 3
- 235000010323 ascorbic acid Nutrition 0.000 description 3
- 239000011668 ascorbic acid Substances 0.000 description 3
- 229910052802 copper Inorganic materials 0.000 description 3
- 239000010949 copper Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 241000223105 Trypanosoma brucei Species 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000003638 chemical reducing agent Substances 0.000 description 2
- 239000003599 detergent Substances 0.000 description 2
- 230000003071 parasitic effect Effects 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- DQJCDTNMLBYVAY-ZXXIYAEKSA-N (2S,5R,10R,13R)-16-{[(2R,3S,4R,5R)-3-{[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-(ethylamino)-6-hydroxy-2-(hydroxymethyl)oxan-4-yl]oxy}-5-(4-aminobutyl)-10-carbamoyl-2,13-dimethyl-4,7,12,15-tetraoxo-3,6,11,14-tetraazaheptadecan-1-oic acid Chemical compound NCCCC[C@H](C(=O)N[C@@H](C)C(O)=O)NC(=O)CC[C@H](C(N)=O)NC(=O)[C@@H](C)NC(=O)C(C)O[C@@H]1[C@@H](NCC)C(O)O[C@H](CO)[C@H]1O[C@H]1[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O1 DQJCDTNMLBYVAY-ZXXIYAEKSA-N 0.000 description 1
- UMCMPZBLKLEWAF-BCTGSCMUSA-N 3-[(3-cholamidopropyl)dimethylammonio]propane-1-sulfonate Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)C)[C@@]2(C)[C@@H](O)C1 UMCMPZBLKLEWAF-BCTGSCMUSA-N 0.000 description 1
- 208000000230 African Trypanosomiasis Diseases 0.000 description 1
- 241000701931 Canine parvovirus Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000714165 Feline leukemia virus Species 0.000 description 1
- 241000710198 Foot-and-mouth disease virus Species 0.000 description 1
- 241000224467 Giardia intestinalis Species 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 241000711549 Hepacivirus C Species 0.000 description 1
- 241000700721 Hepatitis B virus Species 0.000 description 1
- 241000709721 Hepatovirus A Species 0.000 description 1
- 241000701044 Human gammaherpesvirus 4 Species 0.000 description 1
- 241000725303 Human immunodeficiency virus Species 0.000 description 1
- 241000701806 Human papillomavirus Species 0.000 description 1
- 241000223960 Plasmodium falciparum Species 0.000 description 1
- 229920000805 Polyaspartic acid Polymers 0.000 description 1
- 229920002873 Polyethylenimine Polymers 0.000 description 1
- 108010039918 Polylysine Proteins 0.000 description 1
- 241000711798 Rabies lyssavirus Species 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 229910052793 cadmium Inorganic materials 0.000 description 1
- BDOSMKKIYDKNTQ-UHFFFAOYSA-N cadmium atom Chemical compound [Cd] BDOSMKKIYDKNTQ-UHFFFAOYSA-N 0.000 description 1
- 150000001879 copper Chemical class 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 229940085435 giardia lamblia Drugs 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 208000029080 human African trypanosomiasis Diseases 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000083 poly(allylamine) Polymers 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 108010064470 polyaspartate Proteins 0.000 description 1
- 229920000656 polylysine Polymers 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 201000002612 sleeping sickness Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021147395A JP7293296B2 (ja) | 2015-08-04 | 2021-09-10 | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
| JP2023093650A JP7485834B2 (ja) | 2015-08-04 | 2023-06-07 | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
| JP2024074611A JP2024099812A (ja) | 2015-08-04 | 2024-05-02 | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562201051P | 2015-08-04 | 2015-08-04 | |
| US62/201,051 | 2015-08-04 | ||
| PCT/US2016/045606 WO2017024163A1 (en) | 2015-08-04 | 2016-08-04 | Signal amplification in solution-based plasmonic specific-binding partner assays |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021147395A Division JP7293296B2 (ja) | 2015-08-04 | 2021-09-10 | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018528417A JP2018528417A (ja) | 2018-09-27 |
| JP2018528417A5 true JP2018528417A5 (enExample) | 2019-09-12 |
| JP6944438B2 JP6944438B2 (ja) | 2021-10-06 |
Family
ID=57943715
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018505669A Active JP6944438B2 (ja) | 2015-08-04 | 2016-08-04 | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
| JP2021147395A Active JP7293296B2 (ja) | 2015-08-04 | 2021-09-10 | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
| JP2023093650A Active JP7485834B2 (ja) | 2015-08-04 | 2023-06-07 | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
| JP2024074611A Pending JP2024099812A (ja) | 2015-08-04 | 2024-05-02 | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021147395A Active JP7293296B2 (ja) | 2015-08-04 | 2021-09-10 | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
| JP2023093650A Active JP7485834B2 (ja) | 2015-08-04 | 2023-06-07 | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
| JP2024074611A Pending JP2024099812A (ja) | 2015-08-04 | 2024-05-02 | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US9835622B2 (enExample) |
| EP (2) | EP4465021A3 (enExample) |
| JP (4) | JP6944438B2 (enExample) |
| CN (2) | CN107864670A (enExample) |
| AU (2) | AU2016301375B2 (enExample) |
| CA (2) | CA3227799A1 (enExample) |
| DK (1) | DK3331818T3 (enExample) |
| ES (1) | ES2989755T3 (enExample) |
| FI (1) | FI3331818T3 (enExample) |
| HU (1) | HUE067974T2 (enExample) |
| PL (1) | PL3331818T3 (enExample) |
| PT (1) | PT3331818T (enExample) |
| WO (1) | WO2017024163A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3489685T3 (da) | 2011-11-21 | 2023-12-04 | Zoetis Services Llc | Signalforstærkning i sidestrømning og tilsvarende immunoassays |
| TWI691716B (zh) | 2014-08-13 | 2020-04-21 | 美商艾巴希斯公司 | 電漿特異性結合搭配物檢定中之信號放大 |
| JP6944438B2 (ja) | 2015-08-04 | 2021-10-06 | ゾエティス サービシズ リミテッド ライアビリティ カンパニー | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
| KR102654470B1 (ko) | 2017-01-30 | 2024-04-05 | 조에티스 서비시즈 엘엘씨 | 용액-기반 플라스몬 특이적-결합 파트너 검정 및 금속성 나노구조체 |
| CN110865182B (zh) * | 2019-11-19 | 2023-06-27 | 东莞市东阳光诊断产品有限公司 | 一种阻断剂及其在免疫检测中的应用 |
| CN113376374A (zh) * | 2020-04-03 | 2021-09-10 | 上海桀蒙生物技术有限公司 | 病毒蛋白抗原检测工具的制备和使用方法 |
| CA3187399A1 (en) * | 2020-08-07 | 2022-02-10 | Mounir A. Koussa | Kinetic modulation for magnetic analyte detection |
| US20220163522A1 (en) * | 2020-11-23 | 2022-05-26 | Arizona Board Of Regents On Behalf Of Arizona State University | Compositions and methods for rapid covid-19 detection |
| PL445690A1 (pl) * | 2023-07-27 | 2025-02-03 | Politechnika Gdańska | Układ do wykrywania białka w próbce materiału biologicznego w postaci płynnej i sposób do wykrywania białka realizowany za pomocą tego układu |
Family Cites Families (104)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4704366A (en) | 1984-06-22 | 1987-11-03 | Bio-Rad Laboratories, Inc. | Process for binding IgG to protein A |
| US5061381A (en) | 1990-06-04 | 1991-10-29 | Abaxis, Inc. | Apparatus and method for separating cells from biological fluids |
| US5122284A (en) | 1990-06-04 | 1992-06-16 | Abaxis, Inc. | Apparatus and method for optically analyzing biological fluids |
| US5186844A (en) | 1991-04-01 | 1993-02-16 | Abaxis, Inc. | Apparatus and method for continuous centrifugal blood cell separation |
| US5413732A (en) * | 1991-08-19 | 1995-05-09 | Abaxis, Inc. | Reagent compositions for analytical testing |
| US5304348A (en) | 1992-02-11 | 1994-04-19 | Abaxis, Inc. | Reagent container for analytical rotor |
| WO1993019827A1 (en) | 1992-04-02 | 1993-10-14 | Abaxis, Inc. | Analytical rotor with dye mixing chamber |
| JP3706214B2 (ja) | 1996-10-28 | 2005-10-12 | 株式会社三菱化学ヤトロン | 免疫学的分析方法 |
| US5939021A (en) | 1997-01-23 | 1999-08-17 | Hansen; W. Peter | Homogeneous binding assay |
| US6180415B1 (en) * | 1997-02-20 | 2001-01-30 | The Regents Of The University Of California | Plasmon resonant particles, methods and apparatus |
| US6344272B1 (en) | 1997-03-12 | 2002-02-05 | Wm. Marsh Rice University | Metal nanoshells |
| US7144627B2 (en) | 1997-03-12 | 2006-12-05 | William Marsh Rice University | Multi-layer nanoshells comprising a metallic or conducting shell |
| US6699724B1 (en) | 1998-03-11 | 2004-03-02 | Wm. Marsh Rice University | Metal nanoshells for biosensing applications |
| JP2000028612A (ja) | 1998-07-07 | 2000-01-28 | Nitto Denko Corp | 免疫学的検査方法および免疫学的検査キット |
| JP3841559B2 (ja) | 1998-07-07 | 2006-11-01 | 日東電工株式会社 | 免疫学的検査方法および免疫学的検査キット |
| JP3298836B2 (ja) | 1998-11-12 | 2002-07-08 | アークレイ株式会社 | 検体分析用具 |
| EP1212458A4 (en) | 1999-07-30 | 2005-01-05 | Surromed Inc | INSTRUMENTS, METHODS AND REAGENTS FOR PLASMON SURFACE RESONANCE |
| JP2003514224A (ja) * | 1999-11-12 | 2003-04-15 | サーロメッド・インコーポレーテッド | 表面プラズモン共鳴を使用するバイオセンシング |
| AU2002246587A1 (en) | 2000-11-03 | 2002-08-06 | Wm. Marsh Rice University | Partial coverage metal nanoshells and method of making same |
| US6861263B2 (en) | 2001-01-26 | 2005-03-01 | Surromed, Inc. | Surface-enhanced spectroscopy-active sandwich nanoparticles |
| WO2002096262A2 (en) | 2001-05-25 | 2002-12-05 | Northwestern University | Non-alloying core shell nanoparticles |
| EP1428028A2 (de) * | 2001-09-14 | 2004-06-16 | Reinhard Zeidler | Identifizierung von antigenen durch xenogene, allogene oder autologe antikörper-vermittelte präzipitation |
| US7135054B2 (en) | 2001-09-26 | 2006-11-14 | Northwestern University | Nanoprisms and method of making them |
| CN1417586A (zh) | 2001-11-05 | 2003-05-14 | 福州市迈新生物技术开发公司 | 一种免疫检测信号放大系统和它的制备方法及其应用 |
| US6970239B2 (en) | 2002-06-12 | 2005-11-29 | Intel Corporation | Metal coated nanocrystalline silicon as an active surface enhanced Raman spectroscopy (SERS) substrate |
| US7212692B2 (en) | 2002-11-08 | 2007-05-01 | Ming Yan | Multiple array surface plasmon resonance biosensor |
| JP4787938B2 (ja) | 2003-03-28 | 2011-10-05 | ザ・プロウボウスト・フェロウズ・ファウンデーション・スカラーズ・アンド・ザ・アザー・メンバーズ・オブ・ボード・オブ・ザ・カレッジ・オブ・ザ・ホリー・アンド・アンデバイデッド・トリニティ・オブ・クイーン | 銀ナノ粒子を用いた検体検出用センサ |
| KR100531760B1 (ko) | 2003-04-28 | 2005-11-29 | 대한민국(관리부서 : 농림부 국립수의과학검역원) | 구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트 |
| US20060240573A1 (en) | 2003-07-29 | 2006-10-26 | Lamdagen, Llc | Optical system including nanostructures for biological or chemical sensing |
| GB0321937D0 (en) | 2003-09-19 | 2003-10-22 | Univ Liverpool | Nanoparticle conjugates and method of production thereof |
| US7573946B2 (en) * | 2003-12-31 | 2009-08-11 | Intel Corporation | Apparatus and associated methods to perform space-frequency interleaving in a multicarrier wireless communication channel |
| JP4109205B2 (ja) | 2004-01-07 | 2008-07-02 | 富士フイルム株式会社 | 被検体検出方法 |
| US20080227219A1 (en) | 2004-11-17 | 2008-09-18 | Frank Gamez | Electrochemiluminescent assay |
| CN1296492C (zh) | 2004-11-18 | 2007-01-24 | 博奥生物有限公司 | 一种基于生物芯片检测能结合特异序列的核酸结合蛋白的方法 |
| US7405054B1 (en) | 2004-12-13 | 2008-07-29 | University Of Washington Uw Tech Transfer - Invention Licensing | Signal amplification method for surface plasmon resonance-based chemical detection |
| US7485471B1 (en) | 2004-12-17 | 2009-02-03 | Intel Corporation | Detection of enhanced multiplex signals by surface enhanced Raman spectroscopy |
| CA2592254A1 (en) | 2004-12-31 | 2006-07-13 | Genentech, Inc. | Detecting human antibodies in non-human serum |
| US8628727B2 (en) | 2005-04-08 | 2014-01-14 | Northwestern University | Compositions, devices and methods for SERS and LSPR |
| US20060246513A1 (en) * | 2005-05-02 | 2006-11-02 | Bohannon Robert C | Method and device to detect the presence of analytes in a sample |
| WO2007053201A2 (en) | 2005-06-15 | 2007-05-10 | University Of Maryland Biotechnology Institute | Bioassays using plasmonic scattering from noble metal nanostructures |
| US20070092978A1 (en) | 2005-10-20 | 2007-04-26 | Ronald Mink | Target ligand detection |
| JP5442179B2 (ja) * | 2005-10-21 | 2014-03-12 | アルフレッサファーマ株式会社 | 反応性物質が結合した微小粒子の沈降抑制方法および該微小粒子含有試薬 |
| CN103357007A (zh) * | 2005-10-25 | 2013-10-23 | 人工细胞技术公司 | 免疫原性组合物及其使用方法 |
| WO2007061793A2 (en) | 2005-11-18 | 2007-05-31 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SCIENCES, CENTERS FOR DISEASE CONTROL AND PREVENTION | Modified cardiolipin and uses therefor |
| US7790066B2 (en) | 2006-03-03 | 2010-09-07 | William Marsh Rice University | Nanorice particles: hybrid plasmonic nanostructures |
| JP4810304B2 (ja) | 2006-05-12 | 2011-11-09 | キヤノン株式会社 | 化学センサ素子及びその製造方法 |
| US8426152B2 (en) * | 2007-01-03 | 2013-04-23 | Lamdagen Corporation | Enzymatic assay for LSPR |
| EP2126581B1 (en) | 2007-03-20 | 2014-07-09 | Becton Dickinson and Company | Assays using surface-enhanced raman spectroscopy (sers)-active particles |
| JP2009150708A (ja) | 2007-12-19 | 2009-07-09 | Canon Inc | 標的物質の検出方法及び検査キット |
| US8808420B2 (en) | 2007-12-21 | 2014-08-19 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin | Process for preparing nanoparticles |
| US20100279272A1 (en) * | 2008-02-13 | 2010-11-04 | Michael Craig Burrell | Multiplexed analysis methods using sers-active nanoparticles |
| WO2009117510A2 (en) | 2008-03-20 | 2009-09-24 | Abaxis, Inc. | Multi-wavelength analyses of sol-particle specific binding assays |
| WO2010006201A2 (en) | 2008-07-10 | 2010-01-14 | Abaxis, Inc. | Methods of reducing non-specific interaction in metal nanoparticle assays |
| US8846319B2 (en) | 2008-12-03 | 2014-09-30 | Abaxis, Inc. | Lateral flow strip assay with immobilized conjugate |
| US8313915B2 (en) | 2009-01-21 | 2012-11-20 | Gundersen Lutheran Medical Foundation, Inc. | Early detection of canine lyme disease by specific peptides and antibodies |
| WO2010091293A1 (en) * | 2009-02-06 | 2010-08-12 | The Regents Of The University Of California | Plasmonic system for detecting binding of biological molecules |
| MX2011009019A (es) | 2009-02-27 | 2011-09-29 | Beckman Coulter Inc | Ensayos homogeneos de fase de solucion. |
| WO2010116345A1 (en) | 2009-04-08 | 2010-10-14 | National University Of Ireland, Galway | Silver nanoplates |
| JP5563789B2 (ja) | 2009-06-11 | 2014-07-30 | 富士フイルム株式会社 | 検出方法 |
| US9274125B2 (en) | 2009-10-30 | 2016-03-01 | Kyowa Medex Co., Ltd. | Method and kit for measuring component in the presence of fatty acid alkanolamide or nonionic polyoxyethylene surfactant |
| US8568989B2 (en) | 2009-11-17 | 2013-10-29 | Abaxis, Inc. | Peptides and methods for the detection of Lyme disease antibodies |
| AU2010321790B2 (en) | 2009-11-20 | 2016-08-04 | Zoetis Services Llc | Peptides, devices, and methods for the detection of Ehrlichia antibodies |
| WO2011065747A2 (ko) | 2009-11-24 | 2011-06-03 | 한국생명공학연구원 | 나노입자를 이용한 미생물의 고속 검출방법 |
| US9308582B2 (en) | 2009-12-24 | 2016-04-12 | Yi Sun | Solution stable and chemically reactive metallic nanoparticles |
| EP2354792A1 (en) | 2010-02-08 | 2011-08-10 | Biomonitor A/S | Method for detecting anti-drug antibodies |
| ES2636908T3 (es) | 2010-04-27 | 2017-10-10 | Ventana Medical Systems, Inc. | Conjugados de nanopartícula-anticuerpo y procedimientos para producir y usar dichos conjugados |
| US20130071619A1 (en) | 2010-05-28 | 2013-03-21 | Nippon Steel & Sumikin Chemical Co., Ltd. | Metal fine-particle composite and method for fabricating the same |
| JP5822239B2 (ja) | 2010-12-08 | 2015-11-24 | 公立大学法人大阪府立大学 | 金属ナノ粒子集積構造体を利用した被検出物質の検出装置および方法 |
| JP5614278B2 (ja) | 2010-12-24 | 2014-10-29 | セイコーエプソン株式会社 | センサーチップ、センサーチップの製造方法、検出装置 |
| CN102103145B (zh) | 2011-02-24 | 2013-01-16 | 南京基蛋生物科技有限公司 | 一种双放大系统的胶体金试纸条及其制备方法 |
| US8697129B2 (en) | 2011-03-02 | 2014-04-15 | Imra America, Inc. | Stable colloidal gold nanoparticles with controllable surface modification and functionalization |
| WO2012125693A2 (en) | 2011-03-15 | 2012-09-20 | Northwestern University | Multifunctional metal nanoparticles having a polydopamine-based surface and methods of making and using the same |
| JP5703098B2 (ja) | 2011-03-31 | 2015-04-15 | 富士フイルム株式会社 | 生体分子検出装置および生体分子検出方法 |
| US20130230717A1 (en) | 2011-09-02 | 2013-09-05 | Washington University In St. Louis | Copper nanostructures and methods for their preparation |
| US8758772B2 (en) | 2011-11-04 | 2014-06-24 | Abaxis, Inc. | Peptides and methods for the detection of lyme disease antibodies |
| CH705758B1 (fr) | 2011-11-15 | 2016-03-31 | Metalor Technologies Int | Nanoparticules cœur-coquille métal-silice, procédé de fabrication et dispositif de test par immunochromatographie comprenant de telles nanoparticules. |
| DK3489685T3 (da) | 2011-11-21 | 2023-12-04 | Zoetis Services Llc | Signalforstærkning i sidestrømning og tilsvarende immunoassays |
| US9823246B2 (en) | 2011-12-28 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon |
| US20130189793A1 (en) | 2012-01-20 | 2013-07-25 | Wei Qian | Stable Colloidal Suspensions Of Gold Nanoconjugates And The Method For Preparing The Same |
| EP2810067A4 (en) | 2012-01-31 | 2015-12-09 | American University Of Cairo Auc | DIRECT DETECTION OF ILLEGAL BIOMARKERS IN CLINICAL SAMPLES USING CATIONIC NANOPARTICLE BASED ASSAYS AND VERSATILE AND GREEN METHODS FOR SYNTHESIS FROM ANISOTROPIC SILVER NANOSTRUCTURES |
| EP2625966A1 (en) * | 2012-02-13 | 2013-08-14 | Bionanoplus, S.L. | Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof |
| TWI435843B (zh) | 2012-04-27 | 2014-05-01 | Univ Nat Taiwan | 奈米顆粒的製造方法 |
| WO2013169640A1 (en) | 2012-05-05 | 2013-11-14 | Academia Sinica | Diaminobenzoic or ortho-phenylene diamine conjugated peptides as functional saccharide tagging reagents |
| WO2014020293A1 (en) | 2012-07-31 | 2014-02-06 | Imperial Innovations Limited | Assay |
| CN105051541B (zh) | 2012-10-11 | 2017-07-04 | 爱贝斯股份有限公司 | 用于检测埃里希体属抗体的肽、装置和方法 |
| EP2906286B1 (en) | 2012-10-11 | 2017-06-14 | Nanocomposix, Inc. | Silver nanoplate compositions and methods |
| US9441301B2 (en) * | 2012-12-06 | 2016-09-13 | Nanyang Technological University | Method for forming a bimetallic core-shell nanostructure |
| WO2014158272A1 (en) | 2013-03-14 | 2014-10-02 | Abbott Laboratories | Hcv antigen-antibody combination assay and methods and compositions for use therein |
| FR3003353B1 (fr) | 2013-03-14 | 2015-03-06 | Horiba Abx Sas | Nouvelle methode de dosage en flux d'un objet d'interet |
| CN105209616A (zh) | 2013-03-14 | 2015-12-30 | 雅培制药有限公司 | 用于改进的抗体检测的hcv ns3重组抗原及其突变体 |
| JP2014228385A (ja) | 2013-05-22 | 2014-12-08 | キヤノン株式会社 | 免疫試験方法および免疫試験キット |
| WO2014197222A1 (en) | 2013-06-05 | 2014-12-11 | Purdue Research Foundation | Titanium nitride plasmonic nanoparticles for clinical therapeutic applications |
| CN103335984B (zh) | 2013-06-09 | 2015-10-28 | 清华大学 | 一种基于lspr的无实体壁微阵列芯片及其应用 |
| EP3028043A4 (en) * | 2013-07-30 | 2017-04-19 | Bio-rad Laboratories, Inc. | Multiplex blocker beads for immunoassays |
| JP2015102337A (ja) | 2013-11-21 | 2015-06-04 | 凸版印刷株式会社 | 粒子の単分散状態維持方法及び分析対象物の検出方法 |
| WO2015130980A1 (en) | 2014-02-26 | 2015-09-03 | Lamdagen Corporation | Digital lspr for enhanced assay sensitivity |
| US10024800B2 (en) | 2014-04-15 | 2018-07-17 | Rutgers, The State University Of New Jersey | Gold nanostar substrates for SERS sensing in the femtomolar regime |
| US10518331B2 (en) | 2014-07-11 | 2019-12-31 | Northwestern University | Synthesis of uniform anisotropic nanoparticles |
| US20160202251A1 (en) | 2014-08-01 | 2016-07-14 | Beacle Inc. | Virus-like particle for use in immunoassay, blocking agent for use in the immunoassay, and kit comprising the virus-like particle and the blocking agent |
| TWI691716B (zh) | 2014-08-13 | 2020-04-21 | 美商艾巴希斯公司 | 電漿特異性結合搭配物檢定中之信號放大 |
| WO2016134214A1 (en) | 2015-02-19 | 2016-08-25 | Ionica Sciences | Reagents and methods for detecting infectious diseases |
| WO2016170183A1 (en) | 2015-04-24 | 2016-10-27 | Pharmadiagnostics Nv | Improved method of measuring an interaction between molecules |
| JP6944438B2 (ja) | 2015-08-04 | 2021-10-06 | ゾエティス サービシズ リミテッド ライアビリティ カンパニー | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
| KR102654470B1 (ko) | 2017-01-30 | 2024-04-05 | 조에티스 서비시즈 엘엘씨 | 용액-기반 플라스몬 특이적-결합 파트너 검정 및 금속성 나노구조체 |
-
2016
- 2016-08-04 JP JP2018505669A patent/JP6944438B2/ja active Active
- 2016-08-04 PT PT168338895T patent/PT3331818T/pt unknown
- 2016-08-04 CA CA3227799A patent/CA3227799A1/en active Pending
- 2016-08-04 EP EP24187227.4A patent/EP4465021A3/en active Pending
- 2016-08-04 PL PL16833889.5T patent/PL3331818T3/pl unknown
- 2016-08-04 CN CN201680045090.3A patent/CN107864670A/zh active Pending
- 2016-08-04 US US15/228,491 patent/US9835622B2/en active Active
- 2016-08-04 CA CA2991532A patent/CA2991532C/en active Active
- 2016-08-04 CN CN202311388153.3A patent/CN117434261A/zh active Pending
- 2016-08-04 DK DK16833889.5T patent/DK3331818T3/da active
- 2016-08-04 HU HUE16833889A patent/HUE067974T2/hu unknown
- 2016-08-04 EP EP16833889.5A patent/EP3331818B1/en active Active
- 2016-08-04 AU AU2016301375A patent/AU2016301375B2/en active Active
- 2016-08-04 WO PCT/US2016/045606 patent/WO2017024163A1/en not_active Ceased
- 2016-08-04 FI FIEP16833889.5T patent/FI3331818T3/fi active
- 2016-08-04 ES ES16833889T patent/ES2989755T3/es active Active
-
2017
- 2017-10-31 US US15/799,320 patent/US10429383B2/en active Active
-
2019
- 2019-08-20 US US16/545,019 patent/US11215614B2/en active Active
-
2021
- 2021-09-10 JP JP2021147395A patent/JP7293296B2/ja active Active
- 2021-11-29 US US17/536,520 patent/US11614447B2/en active Active
-
2022
- 2022-06-02 AU AU2022203788A patent/AU2022203788B2/en active Active
-
2023
- 2023-02-24 US US18/174,251 patent/US20230333102A1/en active Pending
- 2023-06-07 JP JP2023093650A patent/JP7485834B2/ja active Active
-
2024
- 2024-05-02 JP JP2024074611A patent/JP2024099812A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018528417A5 (enExample) | ||
| Sapsford et al. | Analyzing nanomaterial bioconjugates: a review of current and emerging purification and characterization techniques | |
| Sánchez-Purrà et al. | Surface-enhanced Raman spectroscopy-based sandwich immunoassays for multiplexed detection of Zika and Dengue viral biomarkers | |
| JP7308148B2 (ja) | 溶液ベースのプラズモン特異的結合パートナーアッセイおよび金属ナノ構造体 | |
| JP7539711B2 (ja) | 万能増強剤としての超高輝度蛍光ナノコンストラクト | |
| JP2023099008A5 (enExample) | ||
| JP7293296B2 (ja) | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 | |
| KR102787948B1 (ko) | 플라즈몬 특이적-결합 상대 검정에서 신호 증폭 방법 | |
| JP6799927B2 (ja) | 生体分子検出用試験キット、及びこれを用いた生体分子の検出方法、並びにこれらに用いられる生体分子検出用標識試薬 | |
| KR102897521B1 (ko) | 용액-기반 플라스몬 특이적-결합 파트너 검정 및 금속성 나노구조체 | |
| Dahanayake et al. | A novel approach for qualitative biosensing of anti-leptospiral lgG antibodies in human sera using functionalised silver nanoparticles |