JP2018528229A5 - - Google Patents
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- Publication number
- JP2018528229A5 JP2018528229A5 JP2018515059A JP2018515059A JP2018528229A5 JP 2018528229 A5 JP2018528229 A5 JP 2018528229A5 JP 2018515059 A JP2018515059 A JP 2018515059A JP 2018515059 A JP2018515059 A JP 2018515059A JP 2018528229 A5 JP2018528229 A5 JP 2018528229A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- salt
- heterocyclyl
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562221649P | 2015-09-22 | 2015-09-22 | |
| US62/221,649 | 2015-09-22 | ||
| PCT/EP2016/072216 WO2017050714A1 (en) | 2015-09-22 | 2016-09-20 | Pyridinone dicarboxamide for use as bromodomain inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018528229A JP2018528229A (ja) | 2018-09-27 |
| JP2018528229A5 true JP2018528229A5 (https=) | 2019-10-17 |
| JP6795588B2 JP6795588B2 (ja) | 2020-12-02 |
Family
ID=56943545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018515059A Expired - Fee Related JP6795588B2 (ja) | 2015-09-22 | 2016-09-20 | ブロモドメイン阻害薬としての使用のためのピリジノンジカルボキサミド |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10370356B2 (https=) |
| EP (1) | EP3353162A1 (https=) |
| JP (1) | JP6795588B2 (https=) |
| KR (1) | KR20180052762A (https=) |
| CN (1) | CN108137541B (https=) |
| AU (1) | AU2016326864A1 (https=) |
| CA (1) | CA2998545A1 (https=) |
| RU (1) | RU2018112312A (https=) |
| WO (1) | WO2017050714A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3023765A1 (en) | 2016-05-24 | 2017-11-30 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pyridine dicarboxamide derivatives as bromodomain inhibitors |
| WO2019018584A1 (en) | 2017-07-18 | 2019-01-24 | GiraFpharma LLC | HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS |
| EP3654982A4 (en) | 2017-07-18 | 2021-04-14 | Nuvation Bio Inc. | 1,8-NAPHTHYRIDINONE COMPOUNDS AND THEIR USES |
| GB201716369D0 (en) | 2017-10-06 | 2017-11-22 | Glaxosmithkline Intellectual Property (No 2) Ltd | Compounds |
| GB201716392D0 (en) | 2017-10-06 | 2017-11-22 | Glaxosmithkline Intellectual Property (No 2) Ltd | Compounds |
| EP4389277A3 (en) * | 2017-10-18 | 2024-10-09 | Biotage AB | Sample clean up device and method of using it |
| GB201814167D0 (en) | 2018-08-31 | 2018-10-17 | Glaxosmithkline Ip No 2 Ltd | Compounds |
| CN113226322A (zh) | 2018-10-30 | 2021-08-06 | 诺维逊生物股份有限公司 | 作为bet抑制剂的杂环化合物 |
| EP3911324A4 (en) | 2019-01-18 | 2022-08-17 | Nuvation Bio Inc. | 1,8-NAPHTHYRIDINONE COMPOUNDS AND THEIR USES |
| EP3911323A4 (en) | 2019-01-18 | 2022-11-16 | Nuvation Bio Inc. | HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS |
| EP3997070A4 (en) | 2019-07-02 | 2023-07-26 | Nuvation Bio Inc. | HETEROCYCLIC COMPOUNDS AS BET INHIBITORS |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9004781D0 (en) | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
| ES2330719T3 (es) | 2000-12-28 | 2009-12-15 | SHIONOGI & CO., LTD. | Derivados de 2-piridona con afinidad para el receptor cannabinoide de tipo 2. |
| PT1477186E (pt) * | 2002-02-19 | 2010-02-11 | Shionogi & Co | Antipruriginosos |
| GB0211759D0 (en) | 2002-05-22 | 2002-07-03 | Glaxo Group Ltd | Novel compounds |
| AU2003273675A1 (en) | 2002-10-09 | 2004-05-04 | Wayne R. Danter | Protein tyrosine kinase inhibitors |
| EP1433788A1 (en) | 2002-12-23 | 2004-06-30 | Aventis Pharma Deutschland GmbH | Pyrazole-derivatives as factor Xa inhibitors |
| ES2388434T3 (es) | 2003-11-03 | 2012-10-15 | Glaxo Group Limited | Dispositivo de administración de fluido |
| GB0919423D0 (en) | 2009-11-05 | 2009-12-23 | Glaxosmithkline Llc | Novel compounds |
| GB0919434D0 (en) | 2009-11-05 | 2009-12-23 | Glaxosmithkline Llc | Novel compounds |
| KR20150079963A (ko) | 2012-11-08 | 2015-07-08 | 브리스톨-마이어스 스큅 컴퍼니 | 키나제 조절제로서 유용한 헤테로아릴 치환된 피리딜 화합물 |
| AU2013365926B9 (en) | 2012-12-21 | 2019-01-17 | Zenith Epigenetics Ltd. | Novel heterocyclic compounds as bromodomain inhibitors |
| NZ710765A (en) | 2013-03-14 | 2020-05-29 | Glaxosmithkline Ip No 2 Ltd | 2,3-disubstituted 1 -acyl-4-amino-1,2,3,4-tetrahydroquinoline derivatives and their use as bromodomain inhibitors |
| WO2015011252A1 (en) | 2013-07-26 | 2015-01-29 | F. Hoffmann-La Roche Ag | Pyrimidine-pyridinone serine/threonine kinase inhibitors |
| JP6542212B2 (ja) | 2013-07-31 | 2019-07-10 | ゼニス・エピジェネティクス・リミテッドＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｌｔｄ． | ブロモドメイン阻害剤としての新規キナゾリノン |
| HK1249504A1 (zh) | 2015-09-02 | 2018-11-02 | Glaxosmithkline Intellectual Property (No. 2) Limited | 用作溴结构域抑制剂的吡啶酮二甲酰胺 |
| KR20180059551A (ko) | 2015-10-05 | 2018-06-04 | 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 | 브로모도메인 억제제로서 2-옥소-1,2-디하이드로피리딘-3,5-디카복스아미드 화합물 |
| BR112018070536A2 (pt) | 2016-04-07 | 2019-02-12 | Glaxosmithkline Intellectual Property (No. | composto, composição farmacêutica, combinação, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, e, método de tratamento de uma doença ou condição |
| CA3023765A1 (en) | 2016-05-24 | 2017-11-30 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pyridine dicarboxamide derivatives as bromodomain inhibitors |
-
2016
- 2016-09-20 US US15/762,229 patent/US10370356B2/en active Active
- 2016-09-20 RU RU2018112312A patent/RU2018112312A/ru not_active Application Discontinuation
- 2016-09-20 WO PCT/EP2016/072216 patent/WO2017050714A1/en not_active Ceased
- 2016-09-20 AU AU2016326864A patent/AU2016326864A1/en not_active Abandoned
- 2016-09-20 CN CN201680054893.5A patent/CN108137541B/zh not_active Expired - Fee Related
- 2016-09-20 JP JP2018515059A patent/JP6795588B2/ja not_active Expired - Fee Related
- 2016-09-20 KR KR1020187010968A patent/KR20180052762A/ko not_active Withdrawn
- 2016-09-20 CA CA2998545A patent/CA2998545A1/en not_active Abandoned
- 2016-09-20 EP EP16766979.5A patent/EP3353162A1/en not_active Withdrawn
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