JP2019516761A5 - - Google Patents
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- JP2019516761A5 JP2019516761A5 JP2018561570A JP2018561570A JP2019516761A5 JP 2019516761 A5 JP2019516761 A5 JP 2019516761A5 JP 2018561570 A JP2018561570 A JP 2018561570A JP 2018561570 A JP2018561570 A JP 2018561570A JP 2019516761 A5 JP2019516761 A5 JP 2019516761A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- salt
- condition
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1609096.1 | 2016-05-24 | ||
| GBGB1609096.1A GB201609096D0 (en) | 2016-05-24 | 2016-05-24 | Compounds |
| GB1703274.9 | 2017-03-01 | ||
| GBGB1703274.9A GB201703274D0 (en) | 2017-03-01 | 2017-03-01 | Compound |
| PCT/EP2017/062208 WO2017202742A1 (en) | 2016-05-24 | 2017-05-22 | Pyridine dicarboxamide derivatives as bromodomain inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019516761A JP2019516761A (ja) | 2019-06-20 |
| JP2019516761A5 true JP2019516761A5 (https=) | 2020-07-02 |
| JP6885968B2 JP6885968B2 (ja) | 2021-06-16 |
Family
ID=58739056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018561570A Expired - Fee Related JP6885968B2 (ja) | 2016-05-24 | 2017-05-22 | ブロモドメイン阻害薬としてのピリジンジカルボキサミド誘導体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10844015B2 (https=) |
| EP (1) | EP3464242A1 (https=) |
| JP (1) | JP6885968B2 (https=) |
| KR (1) | KR20190006567A (https=) |
| CN (1) | CN109153646B (https=) |
| AU (1) | AU2017269673A1 (https=) |
| BR (1) | BR112018073524A2 (https=) |
| CA (1) | CA3023765A1 (https=) |
| RU (1) | RU2018142988A (https=) |
| WO (1) | WO2017202742A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1249504A1 (zh) | 2015-09-02 | 2018-11-02 | Glaxosmithkline Intellectual Property (No. 2) Limited | 用作溴结构域抑制剂的吡啶酮二甲酰胺 |
| US10370356B2 (en) | 2015-09-22 | 2019-08-06 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pyridinone dicarboxamide for use as bromodomain inhibitors |
| KR20180059551A (ko) | 2015-10-05 | 2018-06-04 | 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 | 브로모도메인 억제제로서 2-옥소-1,2-디하이드로피리딘-3,5-디카복스아미드 화합물 |
| BR112018070536A2 (pt) | 2016-04-07 | 2019-02-12 | Glaxosmithkline Intellectual Property (No. | composto, composição farmacêutica, combinação, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, e, método de tratamento de uma doença ou condição |
| CA3023765A1 (en) | 2016-05-24 | 2017-11-30 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pyridine dicarboxamide derivatives as bromodomain inhibitors |
| GB201703282D0 (en) * | 2017-03-01 | 2017-04-12 | Glaxosmithkline Intellectual Property (No 2) Ltd | Compounds |
| JOP20190192A1 (ar) | 2017-03-01 | 2019-08-08 | Glaxosmithkline Ip No 2 Ltd | مشتقات بيرازول بوصفها مثبطات برومودومين |
| JP7290627B2 (ja) | 2017-08-17 | 2023-06-13 | ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム | Ａｔｒキナーゼの複素環式阻害剤 |
| GB201814167D0 (en) | 2018-08-31 | 2018-10-17 | Glaxosmithkline Ip No 2 Ltd | Compounds |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9004781D0 (en) | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
| ES2330719T3 (es) | 2000-12-28 | 2009-12-15 | SHIONOGI & CO., LTD. | Derivados de 2-piridona con afinidad para el receptor cannabinoide de tipo 2. |
| DOP2002000332A (es) * | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Inhibidores de piridina de metaloproteinasas de la matriz |
| PT1477186E (pt) | 2002-02-19 | 2010-02-11 | Shionogi & Co | Antipruriginosos |
| AU2003273675A1 (en) * | 2002-10-09 | 2004-05-04 | Wayne R. Danter | Protein tyrosine kinase inhibitors |
| EP1433788A1 (en) | 2002-12-23 | 2004-06-30 | Aventis Pharma Deutschland GmbH | Pyrazole-derivatives as factor Xa inhibitors |
| ES2388434T3 (es) | 2003-11-03 | 2012-10-15 | Glaxo Group Limited | Dispositivo de administración de fluido |
| GB0919434D0 (en) | 2009-11-05 | 2009-12-23 | Glaxosmithkline Llc | Novel compounds |
| GB0919423D0 (en) | 2009-11-05 | 2009-12-23 | Glaxosmithkline Llc | Novel compounds |
| EP2694489B1 (en) | 2011-04-07 | 2017-09-06 | Merck Sharp & Dohme Corp. | C5-c6 oxacyclic-fused thiadiazine dioxide compounds as bace inhibitors, compositions, and their use |
| KR20150079963A (ko) * | 2012-11-08 | 2015-07-08 | 브리스톨-마이어스 스큅 컴퍼니 | 키나제 조절제로서 유용한 헤테로아릴 치환된 피리딜 화합물 |
| AU2013365926B9 (en) | 2012-12-21 | 2019-01-17 | Zenith Epigenetics Ltd. | Novel heterocyclic compounds as bromodomain inhibitors |
| JP6542212B2 (ja) * | 2013-07-31 | 2019-07-10 | ゼニス・エピジェネティクス・リミテッドＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｌｔｄ． | ブロモドメイン阻害剤としての新規キナゾリノン |
| HK1249504A1 (zh) * | 2015-09-02 | 2018-11-02 | Glaxosmithkline Intellectual Property (No. 2) Limited | 用作溴结构域抑制剂的吡啶酮二甲酰胺 |
| US10370356B2 (en) | 2015-09-22 | 2019-08-06 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pyridinone dicarboxamide for use as bromodomain inhibitors |
| KR20180059551A (ko) * | 2015-10-05 | 2018-06-04 | 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 | 브로모도메인 억제제로서 2-옥소-1,2-디하이드로피리딘-3,5-디카복스아미드 화합물 |
| BR112018070536A2 (pt) * | 2016-04-07 | 2019-02-12 | Glaxosmithkline Intellectual Property (No. | composto, composição farmacêutica, combinação, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, e, método de tratamento de uma doença ou condição |
| CA3023765A1 (en) | 2016-05-24 | 2017-11-30 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pyridine dicarboxamide derivatives as bromodomain inhibitors |
| GB201703282D0 (en) | 2017-03-01 | 2017-04-12 | Glaxosmithkline Intellectual Property (No 2) Ltd | Compounds |
-
2017
- 2017-05-22 CA CA3023765A patent/CA3023765A1/en active Pending
- 2017-05-22 EP EP17724567.7A patent/EP3464242A1/en not_active Withdrawn
- 2017-05-22 CN CN201780032102.3A patent/CN109153646B/zh not_active Expired - Fee Related
- 2017-05-22 RU RU2018142988A patent/RU2018142988A/ru not_active Application Discontinuation
- 2017-05-22 US US16/303,211 patent/US10844015B2/en not_active Expired - Fee Related
- 2017-05-22 WO PCT/EP2017/062208 patent/WO2017202742A1/en not_active Ceased
- 2017-05-22 KR KR1020187037391A patent/KR20190006567A/ko not_active Withdrawn
- 2017-05-22 JP JP2018561570A patent/JP6885968B2/ja not_active Expired - Fee Related
- 2017-05-22 BR BR112018073524A patent/BR112018073524A2/pt not_active Application Discontinuation
- 2017-05-22 AU AU2017269673A patent/AU2017269673A1/en not_active Abandoned
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