JP2019516761A5 - - Google Patents
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- JP2019516761A5 JP2019516761A5 JP2018561570A JP2018561570A JP2019516761A5 JP 2019516761 A5 JP2019516761 A5 JP 2019516761A5 JP 2018561570 A JP2018561570 A JP 2018561570A JP 2018561570 A JP2018561570 A JP 2018561570A JP 2019516761 A5 JP2019516761 A5 JP 2019516761A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound
- salt
- condition
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1609096.1 | 2016-05-24 | ||
| GBGB1609096.1A GB201609096D0 (en) | 2016-05-24 | 2016-05-24 | Compounds |
| GBGB1703274.9A GB201703274D0 (en) | 2017-03-01 | 2017-03-01 | Compound |
| GB1703274.9 | 2017-03-01 | ||
| PCT/EP2017/062208 WO2017202742A1 (en) | 2016-05-24 | 2017-05-22 | Pyridine dicarboxamide derivatives as bromodomain inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019516761A JP2019516761A (ja) | 2019-06-20 |
| JP2019516761A5 true JP2019516761A5 (https=) | 2020-07-02 |
| JP6885968B2 JP6885968B2 (ja) | 2021-06-16 |
Family
ID=58739056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018561570A Expired - Fee Related JP6885968B2 (ja) | 2016-05-24 | 2017-05-22 | ブロモドメイン阻害薬としてのピリジンジカルボキサミド誘導体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10844015B2 (https=) |
| EP (1) | EP3464242A1 (https=) |
| JP (1) | JP6885968B2 (https=) |
| KR (1) | KR20190006567A (https=) |
| CN (1) | CN109153646B (https=) |
| AU (1) | AU2017269673A1 (https=) |
| BR (1) | BR112018073524A2 (https=) |
| CA (1) | CA3023765A1 (https=) |
| RU (1) | RU2018142988A (https=) |
| WO (1) | WO2017202742A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6532599B2 (ja) | 2015-09-02 | 2019-06-19 | グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ （Ｎｏ．２） Ｌｉｍｉｔｅｄ | ブロモドメイン阻害薬としての使用のためのピリジノンジカルボキサミド |
| CA2998545A1 (en) | 2015-09-22 | 2017-03-30 | Glaxosmithkline Intellectual Property (No.2) Limited | Pyridinone dicarboxamide for use as bromodomain inhibitors |
| KR20180059551A (ko) | 2015-10-05 | 2018-06-04 | 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 | 브로모도메인 억제제로서 2-옥소-1,2-디하이드로피리딘-3,5-디카복스아미드 화합물 |
| US10934272B2 (en) | 2016-04-07 | 2021-03-02 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pyridyl derivatives as bromodomain inhibitors |
| JP6885968B2 (ja) | 2016-05-24 | 2021-06-16 | グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ （Ｎｏ．２） Ｌｉｍｉｔｅｄ | ブロモドメイン阻害薬としてのピリジンジカルボキサミド誘導体 |
| GB201703282D0 (en) | 2017-03-01 | 2017-04-12 | Glaxosmithkline Intellectual Property (No 2) Ltd | Compounds |
| JOP20190192A1 (ar) | 2017-03-01 | 2019-08-08 | Glaxosmithkline Ip No 2 Ltd | مشتقات بيرازول بوصفها مثبطات برومودومين |
| JP7290627B2 (ja) | 2017-08-17 | 2023-06-13 | ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム | Ａｔｒキナーゼの複素環式阻害剤 |
| GB201814167D0 (en) | 2018-08-31 | 2018-10-17 | Glaxosmithkline Ip No 2 Ltd | Compounds |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9004781D0 (en) | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
| KR100828982B1 (ko) | 2000-12-28 | 2008-05-14 | 시오노기세이야쿠가부시키가이샤 | 칸나비노이드 2형 수용체 친화 작용을 갖는 피리돈 유도체 |
| DOP2002000332A (es) * | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Inhibidores de piridina de metaloproteinasas de la matriz |
| ATE447971T1 (de) | 2002-02-19 | 2009-11-15 | Shionogi & Co | Antipruriginosa |
| US7629347B2 (en) * | 2002-10-09 | 2009-12-08 | Critical Outcome Technologies, Inc. | Protein tyrosine kinase inhibitors |
| EP1433788A1 (en) | 2002-12-23 | 2004-06-30 | Aventis Pharma Deutschland GmbH | Pyrazole-derivatives as factor Xa inhibitors |
| CN1901958B (zh) | 2003-11-03 | 2011-03-09 | 葛兰素集团有限公司 | 流体分配装置 |
| GB0919423D0 (en) | 2009-11-05 | 2009-12-23 | Glaxosmithkline Llc | Novel compounds |
| GB0919434D0 (en) | 2009-11-05 | 2009-12-23 | Glaxosmithkline Llc | Novel compounds |
| EP2694489B1 (en) | 2011-04-07 | 2017-09-06 | Merck Sharp & Dohme Corp. | C5-c6 oxacyclic-fused thiadiazine dioxide compounds as bace inhibitors, compositions, and their use |
| BR112015009850A2 (pt) * | 2012-11-08 | 2017-07-11 | Bristol Myers Squibb Co | compostos de piridila substituídos por heteroarila úteis como moduladores de quinase |
| JP2016507496A (ja) | 2012-12-21 | 2016-03-10 | ゼニス・エピジェネティクス・コーポレイションＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｃｏｒｐ． | ブロモドメイン阻害剤としての新規複素環式化合物 |
| JP6542212B2 (ja) * | 2013-07-31 | 2019-07-10 | ゼニス・エピジェネティクス・リミテッドＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｌｔｄ． | ブロモドメイン阻害剤としての新規キナゾリノン |
| JP6532599B2 (ja) * | 2015-09-02 | 2019-06-19 | グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ （Ｎｏ．２） Ｌｉｍｉｔｅｄ | ブロモドメイン阻害薬としての使用のためのピリジノンジカルボキサミド |
| CA2998545A1 (en) | 2015-09-22 | 2017-03-30 | Glaxosmithkline Intellectual Property (No.2) Limited | Pyridinone dicarboxamide for use as bromodomain inhibitors |
| KR20180059551A (ko) | 2015-10-05 | 2018-06-04 | 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 | 브로모도메인 억제제로서 2-옥소-1,2-디하이드로피리딘-3,5-디카복스아미드 화합물 |
| US10934272B2 (en) * | 2016-04-07 | 2021-03-02 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pyridyl derivatives as bromodomain inhibitors |
| JP6885968B2 (ja) | 2016-05-24 | 2021-06-16 | グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ （Ｎｏ．２） Ｌｉｍｉｔｅｄ | ブロモドメイン阻害薬としてのピリジンジカルボキサミド誘導体 |
| GB201703282D0 (en) | 2017-03-01 | 2017-04-12 | Glaxosmithkline Intellectual Property (No 2) Ltd | Compounds |
-
2017
- 2017-05-22 JP JP2018561570A patent/JP6885968B2/ja not_active Expired - Fee Related
- 2017-05-22 WO PCT/EP2017/062208 patent/WO2017202742A1/en not_active Ceased
- 2017-05-22 KR KR1020187037391A patent/KR20190006567A/ko not_active Withdrawn
- 2017-05-22 EP EP17724567.7A patent/EP3464242A1/en not_active Withdrawn
- 2017-05-22 BR BR112018073524A patent/BR112018073524A2/pt not_active Application Discontinuation
- 2017-05-22 US US16/303,211 patent/US10844015B2/en not_active Expired - Fee Related
- 2017-05-22 AU AU2017269673A patent/AU2017269673A1/en not_active Abandoned
- 2017-05-22 RU RU2018142988A patent/RU2018142988A/ru not_active Application Discontinuation
- 2017-05-22 CN CN201780032102.3A patent/CN109153646B/zh not_active Expired - Fee Related
- 2017-05-22 CA CA3023765A patent/CA3023765A1/en active Pending
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