JP2018527903A5 - - Google Patents
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- Publication number
- JP2018527903A5 JP2018527903A5 JP2018502692A JP2018502692A JP2018527903A5 JP 2018527903 A5 JP2018527903 A5 JP 2018527903A5 JP 2018502692 A JP2018502692 A JP 2018502692A JP 2018502692 A JP2018502692 A JP 2018502692A JP 2018527903 A5 JP2018527903 A5 JP 2018527903A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- antigen
- binding fragment
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562195504P | 2015-07-22 | 2015-07-22 | |
| US62/195,504 | 2015-07-22 | ||
| US201662275068P | 2016-01-05 | 2016-01-05 | |
| US62/275,068 | 2016-01-05 | ||
| PCT/US2016/043712 WO2017015622A2 (en) | 2015-07-22 | 2016-07-22 | Gdf11 binding proteins and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018527903A JP2018527903A (ja) | 2018-09-27 |
| JP2018527903A5 true JP2018527903A5 (enExample) | 2019-10-17 |
Family
ID=57834686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018502692A Pending JP2018527903A (ja) | 2015-07-22 | 2016-07-22 | Ｇｄｆ１１結合タンパク質およびその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20180208648A1 (enExample) |
| EP (1) | EP3324996A4 (enExample) |
| JP (1) | JP2018527903A (enExample) |
| AU (1) | AU2016297248A1 (enExample) |
| CA (1) | CA3031430A1 (enExample) |
| WO (1) | WO2017015622A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9458450B2 (en) | 2012-03-15 | 2016-10-04 | Flodesign Sonics, Inc. | Acoustophoretic separation technology using multi-dimensional standing waves |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| CN105939767B (zh) | 2014-01-08 | 2018-04-06 | 弗洛设计声能学公司 | 具有双声电泳腔的声电泳装置 |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11459540B2 (en) | 2015-07-28 | 2022-10-04 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11474085B2 (en) | 2015-07-28 | 2022-10-18 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| US11085035B2 (en) | 2016-05-03 | 2021-08-10 | Flodesign Sonics, Inc. | Therapeutic cell washing, concentration, and separation utilizing acoustophoresis |
| AU2017296040C1 (en) | 2016-07-15 | 2023-06-22 | Acceleron Pharma Inc. | Compositions and methods for treating pulmonary hypertension |
| BR112019001806A2 (pt) | 2016-07-29 | 2019-05-07 | Momenta Pharmaceuticals, Inc. | anticorpos para fcrn e métodos de uso dos mesmos |
| US20200031895A1 (en) * | 2016-12-16 | 2020-01-30 | Biogen Ma Inc. | Stabilized proteolytically activated growth differentiation factor 11 |
| US20200155481A1 (en) * | 2017-05-03 | 2020-05-21 | The Johns Hopkins University | Intramuscular atovaquone for malaria prophylaxis |
| CN114900773A (zh) | 2017-12-14 | 2022-08-12 | 弗洛设计声能学公司 | 声泳系统及其操作方法、控制声换能器及声学系统的方法 |
| KR102649069B1 (ko) | 2018-05-31 | 2024-03-19 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 안면 홍조 개선용 조성물 |
| PT3677278T (pt) | 2018-07-11 | 2022-02-03 | Scholar Rock Inc | Inibidores seletivos da isoforma tgfbeta1 e sua utilização |
| KR102891320B1 (ko) | 2018-07-11 | 2025-11-28 | 스칼러 락, 인크. | 고친화도, 이소형-선택적 TGFβ1 억제제 및 그의 용도 |
| EA202190264A1 (ru) | 2018-07-20 | 2021-05-20 | Момента Фармасьютикалз, Инк. | КОМПОЗИЦИИ АНТИТЕЛ ПРОТИВ FcRn |
| IL280280B2 (en) * | 2018-07-20 | 2024-11-01 | Momenta Pharmaceuticals Inc | Compositions of fcrn antibodies and methods of use thereof |
| CN112261871B (zh) | 2018-07-28 | 2022-05-17 | 韩国外泌体生技有限公司 | 用于使外排体冻干的方法 |
| KR102163806B1 (ko) * | 2018-07-30 | 2020-10-07 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 피지분비 감소용 조성물 |
| CN116199780A (zh) * | 2019-12-24 | 2023-06-02 | 美勒斯公司 | TGF-β-RII结合蛋白质 |
| RU2750267C1 (ru) * | 2020-02-07 | 2021-06-25 | Общество с ограниченной ответственностью «НАУЧНО-ПРОИЗВОДСТВЕННОЕ ОБЪЕДИНЕНИЕ ИН-ВЕТ» | Рекомбинантный ростовой дифференцировочный фактор роста 11 (GDF11), способ его получения, инъекционный препарат для повышения мышечной массы млекопитающих животных и птицы, а также способ использования препарата |
| US20230174620A1 (en) | 2020-04-28 | 2023-06-08 | Acceleron Pharma Inc. | Actrii proteins and use in treating post-capillary pulmonary hypertension |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030167492A1 (en) * | 1994-07-08 | 2003-09-04 | Johns Hopkins University School Of Medicine | Transgenic non-human animals expressing a gdf-11 dominant negative polypeptide, and methods of making and using same |
| DE69534468T2 (de) * | 1994-07-08 | 2006-07-13 | The Johns Hopkins University School Of Medicine | Wachstums-differenzierungsfaktor-11 |
| NZ509609A (en) * | 1998-07-28 | 2003-11-28 | Univ Johns Hopkins Med | Disrupting growth differentiation factor-11 (GDF-11) to increase the muscle and bone tissue in animals |
| US20040131614A1 (en) * | 2002-07-19 | 2004-07-08 | Abbott Biotechnology Ltd. | Treatment of pulmonary disorders using TNFalpha inhibitor |
| EP1740946B1 (en) * | 2004-04-20 | 2013-11-06 | Genmab A/S | Human monoclonal antibodies against cd20 |
| TW200918553A (en) * | 2007-09-18 | 2009-05-01 | Amgen Inc | Human GM-CSF antigen binding proteins |
| US8952130B2 (en) * | 2009-02-24 | 2015-02-10 | The Salk Institute For Biological Studies | Designer ligands of TGF-β superfamily |
| EP3904391B1 (en) * | 2010-03-10 | 2024-07-10 | Genmab A/S | Monoclonal antibodies against c-met |
| WO2013071056A2 (en) * | 2011-11-11 | 2013-05-16 | Duke University | Combination drug therapy for the treatment of solid tumors |
| WO2013148284A1 (en) * | 2012-03-29 | 2013-10-03 | Genentech, Inc. | Antibodies that bind to a pcsk9 cleavage site and methods of use |
| WO2013165972A2 (en) * | 2012-04-30 | 2013-11-07 | Cell Signaling Technology, Inc. | Anti-hepatitis b virus antibodies and use thereof |
| US20150284455A1 (en) * | 2012-11-06 | 2015-10-08 | Scholar Rock, Inc. | Compositions and methods for modulating cell signaling |
| HRP20201914T1 (hr) * | 2013-05-06 | 2021-01-22 | Scholar Rock, Inc. | Sastavi i postupci za modulaciju faktora rasta |
| WO2016073879A2 (en) * | 2014-11-06 | 2016-05-12 | Scholar Rock, Inc. | Transforming growth factor-related antibodies and uses thereof |
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2016
- 2016-07-22 JP JP2018502692A patent/JP2018527903A/ja active Pending
- 2016-07-22 WO PCT/US2016/043712 patent/WO2017015622A2/en not_active Ceased
- 2016-07-22 AU AU2016297248A patent/AU2016297248A1/en not_active Abandoned
- 2016-07-22 US US15/746,467 patent/US20180208648A1/en not_active Abandoned
- 2016-07-22 EP EP16828657.3A patent/EP3324996A4/en not_active Withdrawn
- 2016-07-22 CA CA3031430A patent/CA3031430A1/en not_active Abandoned