JP2018527903A5 - - Google Patents
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- JP2018527903A5 JP2018527903A5 JP2018502692A JP2018502692A JP2018527903A5 JP 2018527903 A5 JP2018527903 A5 JP 2018527903A5 JP 2018502692 A JP2018502692 A JP 2018502692A JP 2018502692 A JP2018502692 A JP 2018502692A JP 2018527903 A5 JP2018527903 A5 JP 2018527903A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- antigen
- binding fragment
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562195504P | 2015-07-22 | 2015-07-22 | |
| US62/195,504 | 2015-07-22 | ||
| US201662275068P | 2016-01-05 | 2016-01-05 | |
| US62/275,068 | 2016-01-05 | ||
| PCT/US2016/043712 WO2017015622A2 (en) | 2015-07-22 | 2016-07-22 | Gdf11 binding proteins and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018527903A JP2018527903A (ja) | 2018-09-27 |
| JP2018527903A5 true JP2018527903A5 (enExample) | 2019-10-17 |
Family
ID=57834686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018502692A Pending JP2018527903A (ja) | 2015-07-22 | 2016-07-22 | Ｇｄｆ１１結合タンパク質およびその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20180208648A1 (enExample) |
| EP (1) | EP3324996A4 (enExample) |
| JP (1) | JP2018527903A (enExample) |
| AU (1) | AU2016297248A1 (enExample) |
| CA (1) | CA3031430A1 (enExample) |
| WO (1) | WO2017015622A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US9458450B2 (en) | 2012-03-15 | 2016-10-04 | Flodesign Sonics, Inc. | Acoustophoretic separation technology using multi-dimensional standing waves |
| CA2935960C (en) | 2014-01-08 | 2023-01-10 | Bart Lipkens | Acoustophoresis device with dual acoustophoretic chamber |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11459540B2 (en) | 2015-07-28 | 2022-10-04 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11474085B2 (en) | 2015-07-28 | 2022-10-18 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11085035B2 (en) | 2016-05-03 | 2021-08-10 | Flodesign Sonics, Inc. | Therapeutic cell washing, concentration, and separation utilizing acoustophoresis |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| CN116531490A (zh) | 2016-07-15 | 2023-08-04 | 阿塞勒隆制药公司 | 用于治疗肺高血压的组合物和方法 |
| WO2018112362A1 (en) * | 2016-12-16 | 2018-06-21 | Biogen Ma Inc. | Stabilized proteolytically activated growth differentiation factor 11 |
| US20200155481A1 (en) * | 2017-05-03 | 2020-05-21 | The Johns Hopkins University | Intramuscular atovaquone for malaria prophylaxis |
| SG11202003907WA (en) | 2017-12-14 | 2020-05-28 | Flodesign Sonics Inc | Acoustic transducer drive and controller |
| KR102649069B1 (ko) | 2018-05-31 | 2024-03-19 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 안면 홍조 개선용 조성물 |
| US12252531B2 (en) | 2018-07-11 | 2025-03-18 | Scholar Rock, Inc. | Methods of screening for high-affinity, isoform-selective TGFβ1 inhibitors |
| HRP20212034T1 (hr) | 2018-07-11 | 2022-04-01 | Scholar Rock, Inc. | Izoformno selektivni inhibitori tgfbeta1 i njihove uporabe |
| US20210299255A1 (en) * | 2018-07-20 | 2021-09-30 | Momenta Pharmaceuticals, Inc. | Compositions of fcrn antibodies and methods of use thereof |
| UA130214C2 (uk) | 2018-07-20 | 2025-12-24 | Момента Фармасьютикалз, Інк. | Фармацевтична композиція антитіл проти fcrn |
| WO2020027466A1 (ko) | 2018-07-28 | 2020-02-06 | 주식회사 엑소코바이오 | 엑소좀의 동결건조 방법 |
| KR102163806B1 (ko) | 2018-07-30 | 2020-10-07 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 피지분비 감소용 조성물 |
| JP7633259B2 (ja) * | 2019-12-24 | 2025-02-19 | メルス ナムローゼ フェンノートシャップ | ＴＧＦ－βＲＩＩ結合タンパク質 |
| RU2750267C1 (ru) * | 2020-02-07 | 2021-06-25 | Общество с ограниченной ответственностью «НАУЧНО-ПРОИЗВОДСТВЕННОЕ ОБЪЕДИНЕНИЕ ИН-ВЕТ» | Рекомбинантный ростовой дифференцировочный фактор роста 11 (GDF11), способ его получения, инъекционный препарат для повышения мышечной массы млекопитающих животных и птицы, а также способ использования препарата |
| EP4142769A4 (en) | 2020-04-28 | 2024-05-15 | Acceleron Pharma Inc. | ACTRII PROTEINS AND USE IN THE TREATMENT OF POSTCAPILLARY PULMONARY HYPERTENSION |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996001845A1 (en) * | 1994-07-08 | 1996-01-25 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-11 |
| US20030167492A1 (en) * | 1994-07-08 | 2003-09-04 | Johns Hopkins University School Of Medicine | Transgenic non-human animals expressing a gdf-11 dominant negative polypeptide, and methods of making and using same |
| AU765832B2 (en) * | 1998-07-28 | 2003-10-02 | Johns Hopkins University School Of Medicine, The | Growth differentiation factor-11 |
| PL218992B1 (pl) * | 2002-07-19 | 2015-02-27 | Abbott Biotech Ltd | Neutralizujące o wysokim powinowactwie izolowane ludzkie przeciwciało anty-TNFα, zastosowanie tego przeciwciała, kryształ zawierający ludzkie przeciwciało anty-TNFα i preparat zawierający ten kryształ |
| WO2005103081A2 (en) * | 2004-04-20 | 2005-11-03 | Genmab A/S | Human monoclonal antibodies against cd20 |
| TW200918553A (en) * | 2007-09-18 | 2009-05-01 | Amgen Inc | Human GM-CSF antigen binding proteins |
| US8952130B2 (en) * | 2009-02-24 | 2015-02-10 | The Salk Institute For Biological Studies | Designer ligands of TGF-β superfamily |
| WO2011110642A2 (en) * | 2010-03-10 | 2011-09-15 | Genmab A/S | Monoclonal antibodies against c-met |
| US9700619B2 (en) * | 2011-11-11 | 2017-07-11 | Duke University | Combination drug therapy for the treatment of solid tumors |
| WO2013148284A1 (en) * | 2012-03-29 | 2013-10-03 | Genentech, Inc. | Antibodies that bind to a pcsk9 cleavage site and methods of use |
| WO2013165972A2 (en) * | 2012-04-30 | 2013-11-07 | Cell Signaling Technology, Inc. | Anti-hepatitis b virus antibodies and use thereof |
| US20150284455A1 (en) * | 2012-11-06 | 2015-10-08 | Scholar Rock, Inc. | Compositions and methods for modulating cell signaling |
| HUE052232T2 (hu) * | 2013-05-06 | 2021-04-28 | Scholar Rock Inc | Készítmények és eljárások növekedési faktor modulálására |
| WO2016073879A2 (en) * | 2014-11-06 | 2016-05-12 | Scholar Rock, Inc. | Transforming growth factor-related antibodies and uses thereof |
-
2016
- 2016-07-22 EP EP16828657.3A patent/EP3324996A4/en not_active Withdrawn
- 2016-07-22 AU AU2016297248A patent/AU2016297248A1/en not_active Abandoned
- 2016-07-22 US US15/746,467 patent/US20180208648A1/en not_active Abandoned
- 2016-07-22 JP JP2018502692A patent/JP2018527903A/ja active Pending
- 2016-07-22 CA CA3031430A patent/CA3031430A1/en not_active Abandoned
- 2016-07-22 WO PCT/US2016/043712 patent/WO2017015622A2/en not_active Ceased