JP2018526416A5 - - Google Patents

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Publication number
JP2018526416A5
JP2018526416A5 JP2018512944A JP2018512944A JP2018526416A5 JP 2018526416 A5 JP2018526416 A5 JP 2018526416A5 JP 2018512944 A JP2018512944 A JP 2018512944A JP 2018512944 A JP2018512944 A JP 2018512944A JP 2018526416 A5 JP2018526416 A5 JP 2018526416A5
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JP
Japan
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compound according
hydrogen
alkyl
aryl
haloalkyl
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JP2018512944A
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English (en)
Japanese (ja)
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JP6966425B2 (ja
JP2018526416A (ja
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Priority claimed from PCT/US2016/050685 external-priority patent/WO2017044567A1/en
Publication of JP2018526416A publication Critical patent/JP2018526416A/ja
Publication of JP2018526416A5 publication Critical patent/JP2018526416A5/ja
Application granted granted Critical
Publication of JP6966425B2 publication Critical patent/JP6966425B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2018512944A 2015-09-09 2016-09-08 抗がん剤としての複素環式の限定された三環系スルホンアミド Expired - Fee Related JP6966425B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562216168P 2015-09-09 2015-09-09
US62/216,168 2015-09-09
PCT/US2016/050685 WO2017044567A1 (en) 2015-09-09 2016-09-08 Heterocyclic constrained tricyclic sulfonamides as anti-cancer agents

Publications (3)

Publication Number Publication Date
JP2018526416A JP2018526416A (ja) 2018-09-13
JP2018526416A5 true JP2018526416A5 (https=) 2019-11-07
JP6966425B2 JP6966425B2 (ja) 2021-11-17

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ID=56940436

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018512944A Expired - Fee Related JP6966425B2 (ja) 2015-09-09 2016-09-08 抗がん剤としての複素環式の限定された三環系スルホンアミド

Country Status (6)

Country Link
US (1) US10221158B2 (https=)
EP (1) EP3347350A1 (https=)
JP (1) JP6966425B2 (https=)
CN (1) CN108349943A (https=)
CA (1) CA2997769A1 (https=)
WO (1) WO2017044567A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015138500A1 (en) 2014-03-11 2015-09-17 Icahn School Of Medicine At Mount Sinai Sulfonamides derived from tricyclyl-2-aminocycloalkanols as anticancer agents
WO2015138496A1 (en) 2014-03-11 2015-09-17 Icahn School Of Medicine At Mount Sinai Constrained tricyclic sulfonamides
CA2997784A1 (en) 2015-09-09 2017-03-16 Icahn School Of Medicine At Mount Sinai Heterocyclic constrained tricyclic sulfonamides as anti-cancer agents
WO2021150695A1 (en) * 2020-01-22 2021-07-29 Icahn School Of Medicine At Mount Sinai Constrained n-substituted tetrahydrobenzoazepine sulfonamides as anticancer and neuroprotective agents
US20230020161A1 (en) * 2020-02-28 2023-01-19 Rappta Therapeutics Oy Tricyclic Modulators of PP2A
EP4121031A4 (en) * 2020-03-20 2024-03-27 Atux Iskay LLC 3-DIARYLMETHYLENE AND THEIR USE
CN114272378B (zh) * 2020-09-27 2023-06-23 四川大学华西医院 一种使cttnbp2nl功能缺失的试剂在制备治疗疾病的药物中的用途
CN116806217A (zh) * 2021-02-08 2023-09-26 拉帕塔疗法公司 蛋白磷酸酶2a(pp2a)的取代的环状调节剂及其使用方法
AU2022216880A1 (en) * 2021-02-08 2023-08-10 Rappta Therapeutics Oy Substituted cyclic modulators of protein phosphatase 2a (pp2a) and methods using same
US20240368105A1 (en) 2021-08-18 2024-11-07 Atux Iskay Llc 2-diarylmethyl-4-aminotetrahydropyran derivatives and related compounds as anticancer, antiinflammatory, antifibrotic and neuroprotective agents
EP4565323A1 (en) * 2022-08-04 2025-06-11 Rappta Therapeutics Oy Aromatic compounds for use as protein phosphatase 2a (pp2a) modulators

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WO2015138500A1 (en) 2014-03-11 2015-09-17 Icahn School Of Medicine At Mount Sinai Sulfonamides derived from tricyclyl-2-aminocycloalkanols as anticancer agents
WO2015138496A1 (en) 2014-03-11 2015-09-17 Icahn School Of Medicine At Mount Sinai Constrained tricyclic sulfonamides
WO2017024229A1 (en) 2015-08-06 2017-02-09 Icahn School Of Medecine At Mount Sinai Stereospecific process for 3-heterocyclylcycloaliphatic-1,2-diols
WO2017044571A1 (en) 2015-09-09 2017-03-16 Icahn School Of Medicine At Mount Sinai Tricyclic sultam sulfonamides as anticancer and neuroprotective agents
WO2017044572A1 (en) 2015-09-09 2017-03-16 Icahn School Of Medicine At Mount Sinai Ring constrained diarylamino sulfonamides as anti-cancer agents
CA2997784A1 (en) 2015-09-09 2017-03-16 Icahn School Of Medicine At Mount Sinai Heterocyclic constrained tricyclic sulfonamides as anti-cancer agents
WO2017044575A1 (en) 2015-09-09 2017-03-16 Icahn School Of Medicine At Mount Sinai Constrained benzhydryl sulfonamides as anticancer and neuroprotective agents

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