JP2018525375A5 - - Google Patents
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- Publication number
- JP2018525375A5 JP2018525375A5 JP2018505409A JP2018505409A JP2018525375A5 JP 2018525375 A5 JP2018525375 A5 JP 2018525375A5 JP 2018505409 A JP2018505409 A JP 2018505409A JP 2018505409 A JP2018505409 A JP 2018505409A JP 2018525375 A5 JP2018525375 A5 JP 2018525375A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- methyl
- phenylamino
- pyridin
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- CUYKNJBYIJFRCU-UHFFFAOYSA-N Nc1cccnc1 Chemical compound Nc1cccnc1 CUYKNJBYIJFRCU-UHFFFAOYSA-N 0.000 description 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N c1ccncc1 Chemical compound c1ccncc1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
- 0 CCC(*)(C(CN1*)C(C)=*)C1=O Chemical compound CCC(*)(C(CN1*)C(C)=*)C1=O 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15179859.2 | 2015-08-05 | ||
| EP15179859 | 2015-08-05 | ||
| EP15200620.1 | 2015-12-16 | ||
| EP15200620 | 2015-12-16 | ||
| PCT/EP2016/068279 WO2017021348A1 (en) | 2015-08-05 | 2016-08-01 | 1h-pyrrol-3-amines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018525375A JP2018525375A (ja) | 2018-09-06 |
| JP2018525375A5 true JP2018525375A5 (https=) | 2019-06-13 |
Family
ID=56611249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018505409A Withdrawn JP2018525375A (ja) | 2015-08-05 | 2016-08-01 | １ｈ−ピロール−３−アミン類 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10308629B2 (https=) |
| EP (1) | EP3331611B1 (https=) |
| JP (1) | JP2018525375A (https=) |
| CN (1) | CN107921286A (https=) |
| CA (1) | CA2994596A1 (https=) |
| WO (1) | WO2017021348A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR100886A1 (es) | 2014-06-17 | 2016-11-09 | Bayer Pharma AG | 3-amino-1,5,6,7-tetrahidro-4h-indol-4-onas |
| AU2016212230B2 (en) | 2015-01-28 | 2019-09-19 | Bayer Pharma Aktiengesellschaft | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives |
| CA2989469A1 (en) * | 2015-06-17 | 2016-12-22 | Bayer Pharma Aktiengesellschaft | 3-amino-1,5,6,7-tetrahydro-4h-indol-4-ones |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| WO2018158175A1 (en) | 2017-02-28 | 2018-09-07 | Bayer Pharma Aktiengesellschaft | Combination of bub1 inhibitors |
| WO2018206547A1 (en) | 2017-05-12 | 2018-11-15 | Bayer Pharma Aktiengesellschaft | Combination of bub1 and atr inhibitors |
| WO2018215282A1 (en) | 2017-05-26 | 2018-11-29 | Bayer Pharma Aktiengesellschaft | Combination of bub1 and pi3k inhibitors |
| IL301532A (en) | 2020-09-23 | 2023-05-01 | Scorpion Therapeutics Inc | History Pyrrolo[2,3-C]pyridin-4-one is useful in cancer treatment |
| WO2022072645A2 (en) | 2020-09-30 | 2022-04-07 | Scorpion Therapeutics, Inc. | Methods for treating cancer |
| TW202229282A (zh) | 2020-09-30 | 2022-08-01 | 美商史考皮恩治療有限公司 | 治療癌症之方法 |
| AU2021358123A1 (en) | 2020-10-05 | 2023-06-08 | Enliven Inc. | 5- and 6-azaindole compounds for inhibition of bcr-abl tyrosine kinases |
| BR112023006531A2 (pt) | 2020-10-09 | 2023-10-03 | Scorpion Therapeutics Inc | Inibidores heterocílicos de egfr e/ou her2, para uso no tratamento de câncer |
| WO2022094271A1 (en) | 2020-10-30 | 2022-05-05 | Scorpion Therapeutics, Inc. | Methods for treating cancer |
| WO2022098992A1 (en) | 2020-11-05 | 2022-05-12 | Scorpion Therapeutics, Inc. | Use of macrocyclic compounds in methods of treating cancer |
| WO2022197913A1 (en) | 2021-03-18 | 2022-09-22 | Scorpion Therapeutics, Inc. | Bicyclic derivatives which can be used to treat cancer |
| WO2023173083A1 (en) | 2022-03-11 | 2023-09-14 | Scorpion Therapeutics, Inc. | Tetrahydroindole derivatives as egfr and/or her2 inhibtors useful for the treatment of cancer |
| WO2024159094A1 (en) * | 2023-01-27 | 2024-08-02 | Enliven Inc. | Pyrimidinyl (hetero)aromatic aminopyridine compounds for inhibition of raf kinases |
| CN121909190A (zh) | 2023-06-08 | 2026-04-21 | 安塔列斯疗法股份有限公司 | 1,5-二氢-4H-吡咯并[3,2-c]吡啶-4-酮用于癌症治疗 |
| CN121712773A (zh) | 2023-06-08 | 2026-03-20 | 安塔列斯疗法股份有限公司 | 1,5-二氢-4h-吡咯并[3,2-c]吡啶-4-酮用于癌症治疗 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2570756T3 (es) * | 2009-06-15 | 2016-05-20 | Nerviano Medical Sciences Srl | Derivados pirimidinilpirrolopiridinona sustituidos, proceso para su preparación y su uso como inhibidores de cinasa |
| WO2013167698A1 (en) * | 2012-05-11 | 2013-11-14 | Bayer Pharma Aktiengesellschaft | Substituted cycloalkenopyrazoles as bub1 inhibitors for the treatment of cancer |
| AR097325A1 (es) * | 2013-08-13 | 2016-03-09 | Gruenenthal Gmbh | Pirroles anillados |
| AR100886A1 (es) * | 2014-06-17 | 2016-11-09 | Bayer Pharma AG | 3-amino-1,5,6,7-tetrahidro-4h-indol-4-onas |
| AU2016212230B2 (en) | 2015-01-28 | 2019-09-19 | Bayer Pharma Aktiengesellschaft | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives |
-
2016
- 2016-08-01 US US15/750,103 patent/US10308629B2/en not_active Expired - Fee Related
- 2016-08-01 EP EP16748101.9A patent/EP3331611B1/en active Active
- 2016-08-01 CA CA2994596A patent/CA2994596A1/en not_active Abandoned
- 2016-08-01 WO PCT/EP2016/068279 patent/WO2017021348A1/en not_active Ceased
- 2016-08-01 CN CN201680046028.6A patent/CN107921286A/zh active Pending
- 2016-08-01 JP JP2018505409A patent/JP2018525375A/ja not_active Withdrawn
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