JP2018526033A5 - - Google Patents

Download PDF

Info

Publication number
JP2018526033A5
JP2018526033A5 JP2018532485A JP2018532485A JP2018526033A5 JP 2018526033 A5 JP2018526033 A5 JP 2018526033A5 JP 2018532485 A JP2018532485 A JP 2018532485A JP 2018532485 A JP2018532485 A JP 2018532485A JP 2018526033 A5 JP2018526033 A5 JP 2018526033A5
Authority
JP
Japan
Prior art keywords
receptor
cancer
cell
dysfunctional
chimeric antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018532485A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018526033A (ja
JP6957471B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/AU2016/050851 external-priority patent/WO2017041143A1/en
Publication of JP2018526033A publication Critical patent/JP2018526033A/ja
Publication of JP2018526033A5 publication Critical patent/JP2018526033A5/ja
Priority to JP2021164222A priority Critical patent/JP7253020B2/ja
Application granted granted Critical
Publication of JP6957471B2 publication Critical patent/JP6957471B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018532485A 2015-09-11 2016-09-10 キメラ抗原受容体およびその使用 Active JP6957471B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021164222A JP7253020B2 (ja) 2015-09-11 2021-10-05 キメラ抗原受容体およびその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2015903719A AU2015903719A0 (en) 2015-09-11 Chimeric antigen receptor and uses thereof
AU2015903719 2015-09-11
PCT/AU2016/050851 WO2017041143A1 (en) 2015-09-11 2016-09-10 Chimeric antigen receptors and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021164222A Division JP7253020B2 (ja) 2015-09-11 2021-10-05 キメラ抗原受容体およびその使用

Publications (3)

Publication Number Publication Date
JP2018526033A JP2018526033A (ja) 2018-09-13
JP2018526033A5 true JP2018526033A5 (enExample) 2020-09-10
JP6957471B2 JP6957471B2 (ja) 2021-11-02

Family

ID=58240468

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2018532485A Active JP6957471B2 (ja) 2015-09-11 2016-09-10 キメラ抗原受容体およびその使用
JP2021164222A Active JP7253020B2 (ja) 2015-09-11 2021-10-05 キメラ抗原受容体およびその使用
JP2023047606A Pending JP2023082052A (ja) 2015-09-11 2023-03-24 キメラ抗原受容体およびその使用
JP2025052912A Pending JP2025098188A (ja) 2015-09-11 2025-03-27 キメラ抗原受容体およびその使用

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2021164222A Active JP7253020B2 (ja) 2015-09-11 2021-10-05 キメラ抗原受容体およびその使用
JP2023047606A Pending JP2023082052A (ja) 2015-09-11 2023-03-24 キメラ抗原受容体およびその使用
JP2025052912A Pending JP2025098188A (ja) 2015-09-11 2025-03-27 キメラ抗原受容体およびその使用

Country Status (8)

Country Link
US (3) US12121539B2 (enExample)
EP (2) EP3347474B1 (enExample)
JP (4) JP6957471B2 (enExample)
KR (2) KR20250058773A (enExample)
CN (2) CN114891116A (enExample)
AU (4) AU2016318230B2 (enExample)
ES (1) ES2848478T3 (enExample)
WO (1) WO2017041143A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SMT202100221T1 (it) 2014-12-05 2021-07-12 Memorial Sloan Kettering Cancer Center Anticorpi bersaglianti l'antigene di maturazione delle cellule e metodi d'uso
WO2017041143A1 (en) * 2015-09-11 2017-03-16 Ctm@Crc Ltd. Chimeric antigen receptors and uses thereof
PL233352B1 (pl) * 2016-09-15 2019-10-31 Adamed Spolka Z Ograniczona Odpowiedzialnoscia Przeciwnowotworowe białko fuzyjne
US11066475B2 (en) 2017-11-01 2021-07-20 Juno Therapeutics, Inc. Chimeric antigen receptors specific for B-cell maturation antigen and encoding polynucleotides
CN111886012A (zh) 2017-11-06 2020-11-03 朱诺治疗学股份有限公司 细胞疗法与γ分泌酶抑制剂的组合
CN111867619A (zh) 2018-01-03 2020-10-30 曲生物制品公司 过继性细胞治疗的先天寻靶
EP3759491A1 (en) * 2018-03-01 2021-01-06 H. Hoffnabb-La Roche Ag Specificity assay for novel target antigen binding moieties
EP3765093A4 (en) * 2018-03-15 2021-12-08 Fundamental Solutions Corporation PROGRAMMABLE IMMUNOCYTE RECEPTOR COMPLEX SYSTEM
JP2021524248A (ja) * 2018-05-21 2021-09-13 バイオセプター・(ユーケー)・リミテッド 修飾されたリンカードメインを有するキメラ抗原受容体およびその使用
CN110856724B (zh) 2018-08-24 2022-05-27 杭州康万达医药科技有限公司 包含核酸及car修饰的免疫细胞的治疗剂及其应用
BR112021008289A2 (pt) 2018-11-01 2021-10-26 Juno Therapeutics, Inc. Métodos para tratamento utilizando receptores de antígeno quimérico específico para antígeno de maturação de célula b
WO2021019222A1 (en) * 2019-07-26 2021-02-04 Biosceptre (Uk) Limited P2x7 receptor targeted therapy
MX2023010646A (es) * 2021-03-11 2023-11-30 Biosceptre Aust Pty Ltd Novedoso sistema de terapia celular.
CA3223086A1 (en) * 2021-09-01 2023-03-09 Patrick Schlegel Methods and compositions for stimulating immune activity
EP4587067A1 (en) * 2022-09-14 2025-07-23 Biosceptre (Aust) Pty Ltd In vivo detection of immune cells
WO2024055077A1 (en) * 2022-09-14 2024-03-21 Biosceptre (Aust) Pty Ltd Enrichment of engineered immune cells
CA3267580A1 (en) * 2022-09-14 2024-03-21 Biosceptre (Aust) Pty Ltd METHODS FOR DETECTING IMMUNE CELLS
WO2025054416A1 (en) * 2023-09-06 2025-03-13 The Regents Of The University Of California Methods for treating cancer

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579821A (en) 1981-11-23 1986-04-01 University Patents, Inc. Control of DNA sequence transcription
US4601978A (en) 1982-11-24 1986-07-22 The Regents Of The University Of California Mammalian metallothionein promoter system
US4940661A (en) 1984-05-17 1990-07-10 Genentech, Inc. Metallothionein transcription control sequences and use thereof
US5512483A (en) 1993-05-21 1996-04-30 Mcgill University Expression vectors responsive to steroid hormones
US5464758A (en) 1993-06-14 1995-11-07 Gossen; Manfred Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters
RU97121687A (ru) 1995-05-26 2005-01-20 Синджента Лимитед (Gb) Ген-переключатель, представляющий ген рецептора экдизона
US5851796A (en) 1995-06-07 1998-12-22 Yale University Autoregulatory tetracycline-regulated system for inducible gene expression in eucaryotes
AUPP991199A0 (en) 1999-04-21 1999-05-13 University Of Sydney, The Methods for diagnosing pre-cancerous and cancerous conditions
AU4533300A (en) 1999-09-16 2001-04-17 Liangqi Zhang A pressure-reducing diaphragm of carburettor
AUPQ968700A0 (en) 2000-08-28 2000-09-21 Intreat Pty Limited Treatment of urinary incontinence
AUPR201500A0 (en) 2000-12-11 2001-01-11 Biosceptre Pty Ltd Methods for identifying pre-neoplastic and neoplastic states in mammals
WO2002057306A1 (en) 2001-01-17 2002-07-25 Intreat Pty Limited Antibodies to non-functional p2x7 receptor diagnosis and treatment of cancers and other conditions
US20030203411A1 (en) * 2001-06-05 2003-10-30 Sabbadini Roger A. Methods of minicell-based delivery
CA2459348C (en) 2001-09-03 2013-06-18 Intreat Pty Limited Antibodies to non-functional p2x7receptor, diagnosis and treatment of cancers and other conditions
CA2402930A1 (en) * 2002-09-19 2004-03-19 William Herman Targeted ligands
EP1751181B1 (en) 2004-06-02 2012-08-15 AdAlta Pty Ltd BINDING MOIETIES BASED ON SHARK IgNAR DOMAINS
WO2008043146A1 (en) 2006-10-10 2008-04-17 Biosceptre International Limited Antibodies against non functional p2x7 receptor
WO2008043145A1 (en) 2006-10-10 2008-04-17 Biosceptre International Limited Hybridomas producing antibodies against non functional p2x7 receptor
CN103298935A (zh) * 2007-08-15 2013-09-11 阿穆尼克斯公司 用于改善生物活性多肽性能的组合物和方法
CA2737126C (en) * 2007-09-14 2018-05-01 Biosceptre International Limited Novel p2x7 epitopes
WO2009033234A1 (en) 2007-09-14 2009-03-19 Biosceptre International Limited Purinergic (p2x) receptors in extra-cellular body fluid
US8840186B2 (en) 2007-11-07 2014-09-23 L&P Swiss Holding Ag Support assembly and corresponding seat structure
EP2318438B1 (en) * 2008-07-04 2016-11-02 Biosceptre (Aust) Pty Ltd Anti-p2x7 peptiden und epitopen
JP5164806B2 (ja) * 2008-11-12 2013-03-21 サンデン株式会社 車両用通信制御装置
CN102858985A (zh) * 2009-07-24 2013-01-02 西格马-奥尔德里奇有限责任公司 基因组编辑方法
US9127059B2 (en) 2009-08-20 2015-09-08 Biosceptre International Limited Anti P2X7 receptor antibodies and fragments thereof
CA2784345C (en) 2009-12-24 2018-11-13 Julian Alexander Barden Antibodies to non-functional oligomeric p2x7 receptors
CN106310245A (zh) 2010-09-10 2017-01-11 生物权威(澳大利亚)有限责任公司 陪伴动物治疗
US20140154241A1 (en) 2010-12-03 2014-06-05 Cyclogenix Ltd Binding peptides i
PH12013501201A1 (en) * 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
EP3693017A1 (en) * 2010-12-14 2020-08-12 University of Maryland, Baltimore Universal anti-tag chimeric antigen receptor-expressing t cells and methods of treating cancer
WO2013003895A1 (en) 2011-07-01 2013-01-10 Biosceptre International Limited Combination therapy
WO2014055657A1 (en) * 2012-10-05 2014-04-10 The Trustees Of The University Of Pennsylvania Use of a trans-signaling approach in chimeric antigen receptors
TR201819571T4 (tr) * 2014-02-14 2019-01-21 Cellectis Hem immün hücrelerde hem de patolojik hücrelerde bulunan antijenleri hedef almak amacıyla değiştirilmiş immünoterapiye yönelik hücreler.
JP7098325B2 (ja) 2014-12-05 2022-07-11 シティ・オブ・ホープ Cs1標的化キメラ抗原レセプター改変t細胞
US20180170992A1 (en) 2015-01-26 2018-06-21 The University Of Chicago CAR T CELLS RECOGNIZING CANCER-SPECIFIC IL 13Ra2
US20180037650A1 (en) 2015-04-02 2018-02-08 Biosceptre (Uk) Limited Pain Treatment
WO2017041143A1 (en) 2015-09-11 2017-03-16 Ctm@Crc Ltd. Chimeric antigen receptors and uses thereof
CN109310764B (zh) 2016-04-15 2022-01-14 达特茅斯大学理事会 高亲和力b7-h6抗体和抗体片段
EP3487877A4 (en) 2016-07-19 2020-01-01 Unum Therapeutics Inc. USE OF THE ANTIBODY COUPLED T CELL RECEPTOR (ACTR) WITH MULTIPLE CANCER ANTIBODIES IN THE TREATMENT OF CANCER
EP3518944A4 (en) 2016-09-30 2020-06-17 Baylor College of Medicine ADAPTIVE CHIMERIC ANTIGENT RECEPTOR T-CELL DESIGN
WO2018071959A1 (en) 2016-10-21 2018-04-26 Biosceptre (Uk) Limited Cytotoxic particles
JP2021524248A (ja) 2018-05-21 2021-09-13 バイオセプター・(ユーケー)・リミテッド 修飾されたリンカードメインを有するキメラ抗原受容体およびその使用
WO2021019222A1 (en) 2019-07-26 2021-02-04 Biosceptre (Uk) Limited P2x7 receptor targeted therapy

Similar Documents

Publication Publication Date Title
JP2018526033A5 (enExample)
JP7737440B2 (ja) 抗ヒトパピローマウイルス(hpv)抗原結合性タンパク質およびその使用方法
CN108884164B (zh) 用于免疫疗法的经修饰细胞
EP3472205B1 (en) Chimeric antigen receptor
CN112368298A (zh) 嵌合跨膜蛋白及其用途
JP2018529327A5 (enExample)
RU2018107802A (ru) Полностью человеческие антитела к мезотелину и иммунные эффекторные клетки, нацеленные на мезотелин
CN115916833B (zh) 靶向b7h3的抗原结合多肽及其应用
CN113646335A (zh) 使用对b细胞成熟抗原具有特异性的嵌合抗原受体的治疗的方法
CN114391021B (zh) TGF-β受体和使用方法
JP2018528786A5 (enExample)
WO2022247795A1 (zh) 靶向Claudin18.2的纳米抗体及其用途
US12331315B2 (en) Chimeric antigen receptor
CN110678480A (zh) 嵌合多肽和改变它们的在细胞膜中的定位的方法
JP2025536940A (ja) 新規cd19バインダー、それを含むcar-t構造体、およびその使用方法
KR20230124656A (ko) 전립선암 키메라 항원 수용체
TWI849430B (zh) Gpc3結合分子
CN112279915A (zh) Icos抗体、基因、载体、宿主细胞和icos拮抗剂
HK40072388A (en) TGF-β RECEPTORS AND METHODS OF USE
WO2024210072A1 (ja) キメラタンパク質、核酸、ベクター、t細胞又はnk細胞、医薬組成物、組み合わせ物、組み合わせ医薬、及び標的抗原結合タンパク質
JP2025539151A (ja) Lilrb4を特異的に結合する合成t細胞受容体抗原受容体およびその使用
US20260035662A1 (en) Chimeric antigen receptor
JP2024514624A (ja) Taci/bcma二重結合分子
HK40109909A (zh) Gpc3结合分子
HK40013683A (en) Chimeric polypeptides and methods of altering their localisation in the cell membrane