JP2018525994A5 - - Google Patents
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- JP2018525994A5 JP2018525994A5 JP2018510109A JP2018510109A JP2018525994A5 JP 2018525994 A5 JP2018525994 A5 JP 2018525994A5 JP 2018510109 A JP2018510109 A JP 2018510109A JP 2018510109 A JP2018510109 A JP 2018510109A JP 2018525994 A5 JP2018525994 A5 JP 2018525994A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- seq
- sample
- splice variants
- leukemia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021074145A JP7256840B2 (ja) | 2015-09-01 | 2021-04-26 | ネオモルフィックｓｆ３ｂ１変異体に関連するスプライスバリアント |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562212876P | 2015-09-01 | 2015-09-01 | |
| US62/212,876 | 2015-09-01 | ||
| PCT/US2016/049490 WO2017040526A2 (en) | 2015-09-01 | 2016-08-30 | Splice variants associated with neomorphic sf3b1 mutants |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021074145A Division JP7256840B2 (ja) | 2015-09-01 | 2021-04-26 | ネオモルフィックｓｆ３ｂ１変異体に関連するスプライスバリアント |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018525994A JP2018525994A (ja) | 2018-09-13 |
| JP2018525994A5 true JP2018525994A5 (https=) | 2019-10-10 |
| JP6876680B2 JP6876680B2 (ja) | 2021-05-26 |
Family
ID=56936518
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018510109A Active JP6876680B2 (ja) | 2015-09-01 | 2016-08-30 | ネオモルフィックｓｆ３ｂ１変異体に関連するスプライスバリアント |
| JP2021074145A Active JP7256840B2 (ja) | 2015-09-01 | 2021-04-26 | ネオモルフィックｓｆ３ｂ１変異体に関連するスプライスバリアント |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021074145A Active JP7256840B2 (ja) | 2015-09-01 | 2021-04-26 | ネオモルフィックｓｆ３ｂ１変異体に関連するスプライスバリアント |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US10889866B2 (https=) |
| EP (2) | EP3910073B1 (https=) |
| JP (2) | JP6876680B2 (https=) |
| ES (1) | ES2887201T3 (https=) |
| WO (1) | WO2017040526A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2887201T3 (es) | 2015-09-01 | 2021-12-22 | Eisai R&D Man Co Ltd | Variantes de empalme asociadas con mutantes neomórficos de SF3B1 |
| SG11201907887SA (en) * | 2017-03-15 | 2019-09-27 | Eisai Co Ltd | Spliceosome mutations and uses thereof |
| EP3662064A4 (en) * | 2017-07-31 | 2021-07-28 | The Johns Hopkins University | COMPOSITIONS AND METHODS OF TARGETING MASAS FOR THE TREATMENT OF CANCER WITH SPLEISSOSOME MUTATIONS |
| WO2019199667A2 (en) * | 2018-04-09 | 2019-10-17 | Keaney Gregg F | Certain pladienolide compounds and methods of use |
| MX2020012940A (es) | 2018-06-01 | 2021-03-25 | Eisai R&D Man Co Ltd | Metodos de uso de moduladores de empalme. |
| JOP20200268A1 (ar) | 2018-06-01 | 2020-10-26 | Eisai R&D Man Co Ltd | تضفير مترافقات عقار جسم مضاد معدل وطرق استخدامها |
| IL262658A (en) * | 2018-10-28 | 2020-04-30 | Memorial Sloan Kettering Cancer Center | Prevention of age related clonal hematopoiesis and diseases associated therewith |
| JP6931860B2 (ja) * | 2019-02-08 | 2021-09-08 | 株式会社Ｚｅｎｉｃｋ | ｍＲＮＡ前駆体の解析方法、情報処理装置、コンピュータプログラム |
| US20220073971A1 (en) * | 2019-02-08 | 2022-03-10 | Zenick Corporation | Method for analyzing mrna precursor, information processing apparatus, and computer program |
| WO2020264177A1 (en) * | 2019-06-26 | 2020-12-30 | Fred Hutchinson Cancer Research Center | Methods and compositions comprising brd9 activating therapies for treating cancers and related disorders |
| CN111518805A (zh) * | 2020-04-30 | 2020-08-11 | 北京航空航天大学 | 一种可用于抑制肿瘤增殖的非编码基因及其应用 |
| ES2891182A1 (es) * | 2020-07-14 | 2022-01-26 | Servicio Andaluz De Salud | Compuestos para el tratamiento del carcinoma hepatocelular |
| CN116507334A (zh) * | 2020-11-04 | 2023-07-28 | 卫材R&D管理有限公司 | 骨髓增生异常综合征（mds）的生物标记物及其使用方法 |
| KR20230104204A (ko) | 2020-11-04 | 2023-07-07 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 골수이형성 증후군(mds)에 대한 바이오마커 및 이를 사용하는 방법 |
| WO2023131866A1 (en) | 2022-01-05 | 2023-07-13 | Eisai R&D Management Co., Ltd. | Biomarkers for myelodysplastic syndrome (mds) and methods of using the same |
| WO2023209074A1 (en) * | 2022-04-28 | 2023-11-02 | Institut National de la Santé et de la Recherche Médicale | Methods of restoring erythropoiesis in patients suffering from a sf3b1 mutant myelodysplastic syndrome by correcting coasy mis-splicing |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6372431B1 (en) * | 1999-11-19 | 2002-04-16 | Incyte Genomics, Inc. | Mammalian toxicological response markers |
| EP1268609B1 (fr) | 2000-02-18 | 2006-05-17 | Centelion | Procede de preparation de polyalkylenimines fonctionnalises, compositions les contenant et leur utilisations |
| US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| TWI311558B (en) | 2001-02-01 | 2009-07-01 | Mercian Corporatio | Novel physiologically active substance |
| US7473767B2 (en) | 2001-07-03 | 2009-01-06 | The Institute For Systems Biology | Methods for detection and quantification of analytes in complex mixtures |
| US20070015271A1 (en) * | 2002-04-04 | 2007-01-18 | Rosen Craig A | Human secreted proteins |
| TWI334866B (en) | 2002-05-29 | 2010-12-21 | Mercian Corp | Novel physiologically active substances |
| RU2338741C2 (ru) | 2002-07-31 | 2008-11-20 | Мершан Корпорейшн | Новые физиологически активные вещества |
| JP4459051B2 (ja) | 2002-07-31 | 2010-04-28 | メルシャン株式会社 | 新規生理活性物質 |
| JP4439401B2 (ja) | 2002-11-29 | 2010-03-24 | メルシャン株式会社 | マクロライド系化合物の製造方法 |
| EP1705247A4 (en) | 2003-11-27 | 2008-08-20 | Mercian Corp | DNA ACCOMPANYING HYDROXYLATION OF A MAKROLIDE COMPOUND |
| CN1977046A (zh) | 2004-07-20 | 2007-06-06 | 卫材R&D管理有限公司 | 编码参与普拉地内酯生物合成的多肽的dna |
| CN101282967B (zh) | 2005-10-13 | 2011-01-26 | 卫材R&D管理有限公司 | 普拉二烯内酯b和普拉二烯内酯d的全合成 |
| WO2008111464A1 (ja) * | 2007-03-05 | 2008-09-18 | Eisai R & D Management Co., Ltd. | スプライシング異常を指標とする抗ガン剤の作用検定方法 |
| US20080312317A1 (en) | 2007-04-12 | 2008-12-18 | Eisai R&D Management Co., Ltd. | 12 membered-ring macrolactam derivatives |
| US8519115B2 (en) | 2008-08-14 | 2013-08-27 | Nanostring Technologies, Inc. | Stable nanoreporters |
| TW201204393A (en) * | 2010-04-16 | 2012-02-01 | Daiichi Sankyo Co Ltd | Diagnostic agent and therapeutic agent of cancer |
| EP2776830B1 (en) * | 2011-11-08 | 2018-05-09 | Genomic Health, Inc. | Method of predicting breast cancer prognosis |
| WO2013086464A1 (en) * | 2011-12-07 | 2013-06-13 | The Broad Institute, Inc. | Markers associated with chronic lymphocytic leukemia prognosis and progression |
| JP6057408B2 (ja) | 2012-03-05 | 2017-01-11 | 国立大学法人 千葉大学 | 癌の予防剤および／または治療剤 |
| US20140275010A1 (en) | 2013-03-12 | 2014-09-18 | Guo Zhu Zheng | Quaternary salts |
| US10113201B2 (en) | 2013-04-05 | 2018-10-30 | The Wistar Institute Of Anatomy And Biology | Methods and compositions for diagnosis of glioblastoma or a subtype thereof |
| UA119458C2 (uk) | 2014-05-15 | 2019-06-25 | Ейсей Р Енд Д Менеджмент Ко., Лтд. | Сполуки піридину пладієноліду та способи застосування |
| ES2887201T3 (es) | 2015-09-01 | 2021-12-22 | Eisai R&D Man Co Ltd | Variantes de empalme asociadas con mutantes neomórficos de SF3B1 |
-
2016
- 2016-08-30 ES ES16766420T patent/ES2887201T3/es active Active
- 2016-08-30 US US15/755,225 patent/US10889866B2/en active Active
- 2016-08-30 EP EP21174658.1A patent/EP3910073B1/en active Active
- 2016-08-30 JP JP2018510109A patent/JP6876680B2/ja active Active
- 2016-08-30 EP EP16766420.0A patent/EP3344780B1/en active Active
- 2016-08-30 WO PCT/US2016/049490 patent/WO2017040526A2/en not_active Ceased
-
2020
- 2020-11-16 US US17/098,940 patent/US11761045B2/en active Active
-
2021
- 2021-04-26 JP JP2021074145A patent/JP7256840B2/ja active Active
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