JP2018524373A - 薬物がコンジュゲートされた二重特異性抗原結合コンストラクト - Google Patents

薬物がコンジュゲートされた二重特異性抗原結合コンストラクト Download PDF

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JP2018524373A
JP2018524373A JP2018501976A JP2018501976A JP2018524373A JP 2018524373 A JP2018524373 A JP 2018524373A JP 2018501976 A JP2018501976 A JP 2018501976A JP 2018501976 A JP2018501976 A JP 2018501976A JP 2018524373 A JP2018524373 A JP 2018524373A
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antigen
construct
binding
drug
amino acid
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JP2018524373A5 (enExample
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ゴードン イウ コン エング
ゴードン イウ コン エング
レオナード ジー． プレスタ
レオナード ジー． プレスタ
フォン クロイデンシュタイン トマス スプレッター
フォン クロイデンシュタイン トマス スプレッター
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ザイムワークス，インコーポレイテッド
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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