JP2018519508A5 - - Google Patents
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- JP2018519508A5 JP2018519508A5 JP2017562628A JP2017562628A JP2018519508A5 JP 2018519508 A5 JP2018519508 A5 JP 2018519508A5 JP 2017562628 A JP2017562628 A JP 2017562628A JP 2017562628 A JP2017562628 A JP 2017562628A JP 2018519508 A5 JP2018519508 A5 JP 2018519508A5
- Authority
- JP
- Japan
- Prior art keywords
- gitr
- time point
- seq
- tumor
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562170579P | 2015-06-03 | 2015-06-03 | |
| US62/170,579 | 2015-06-03 | ||
| PCT/US2016/035514 WO2016196792A1 (en) | 2015-06-03 | 2016-06-02 | Anti-gitr antibodies for cancer diagnostics |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018519508A JP2018519508A (ja) | 2018-07-19 |
| JP2018519508A5 true JP2018519508A5 (cg-RX-API-DMAC7.html) | 2019-06-27 |
| JP6812364B2 JP6812364B2 (ja) | 2021-01-13 |
Family
ID=56194564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017562628A Expired - Fee Related JP6812364B2 (ja) | 2015-06-03 | 2016-06-02 | 癌診断用抗ｇｉｔｒ抗体 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10690674B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3304079B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6812364B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN107743586B (cg-RX-API-DMAC7.html) |
| BR (1) | BR112017025297A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2988115A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA201792497A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2810856T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2017015260A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016196792A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
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| PT3151921T (pt) | 2014-06-06 | 2019-11-21 | Bristol Myers Squibb Co | Anticorpos contra recetor do fator de necrose tumoral induzido por glicocorticoide e utilizações dos mesmos |
| GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
| ES2810856T3 (es) | 2015-06-03 | 2021-03-09 | Bristol Myers Squibb Co | Anticuerpos ANTI-GITR para diagnóstico de cáncer |
| AU2016297249B2 (en) | 2015-07-23 | 2020-11-12 | Inhibrx Biosciences, Inc. | Multivalent and multispecific GITR-binding fusion proteins |
| AU2016341403B2 (en) | 2015-10-22 | 2023-08-03 | Ablynx Nv | GITR agonists |
| US10281374B2 (en) * | 2015-11-04 | 2019-05-07 | Diagnostic Biosystems | Method of pretreatment of biological samples for an analyte-staining assay method |
| BR112018010172A2 (pt) * | 2015-11-19 | 2018-11-21 | Bristol Myers Squibb Co | anticorpos contra receptor de fator de necrose de tumor induzido por glicocorticoide (gitr) e usos dos mesmos |
| CN116903741A (zh) | 2016-06-20 | 2023-10-20 | 科马布有限公司 | 特异性结合于pd-l1的抗体或其抗原结合片段及其用途 |
| CA3054885A1 (en) * | 2017-03-03 | 2018-09-07 | Rinat Neuroscience Corp. | Anti-gitr antibodies and methods of use thereof |
| WO2018185618A1 (en) | 2017-04-03 | 2018-10-11 | Novartis Ag | Anti-cdh6 antibody drug conjugates and anti-gitr antibody combinations and methods of treatment |
| CN110582303A (zh) | 2017-04-20 | 2019-12-17 | Adc治疗有限公司 | 使用抗cd25抗体-药物缀合物的组合疗法 |
| PL3612234T3 (pl) | 2017-04-20 | 2024-09-02 | Adc Therapeutics Sa | Terapia skojarzona z koniugatem anty-AXL przeciwciało-lek |
| AR111651A1 (es) | 2017-04-28 | 2019-08-07 | Novartis Ag | Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación |
| KR20200006115A (ko) | 2017-05-16 | 2020-01-17 | 브리스톨-마이어스 스큅 컴퍼니 | 항-gitr 효능제 항체에 의한 암의 치료 |
| BR112019026564A2 (pt) | 2017-06-14 | 2020-06-30 | Adc Therapeutics Sa | regimes de dosagem para a administração de um adc anti-cd19 |
| WO2018229715A1 (en) | 2017-06-16 | 2018-12-20 | Novartis Ag | Compositions comprising anti-cd32b antibodies and methods of use thereof |
| WO2018235056A1 (en) | 2017-06-22 | 2018-12-27 | Novartis Ag | Il-1beta binding antibodies for use in treating cancer |
| US20200172628A1 (en) | 2017-06-22 | 2020-06-04 | Novartis Ag | Antibody molecules to cd73 and uses thereof |
| TW201904993A (zh) | 2017-06-22 | 2019-02-01 | 瑞士商諾華公司 | IL-1β 結合抗體之用途 |
| CN110785187B (zh) | 2017-06-22 | 2024-04-05 | 诺华股份有限公司 | 针对cd73的抗体分子及其用途 |
| US20200223924A1 (en) | 2017-06-27 | 2020-07-16 | Novartis Ag | Dosage regimens for anti-tim-3 antibodies and uses thereof |
| IL319798A (en) | 2017-07-20 | 2025-05-01 | Novartis Ag | ANTI-LAG-3 Antibody Dosage Regimens and Their Uses |
| JP7279026B2 (ja) | 2017-09-20 | 2023-05-22 | メルサナ セラピューティクス インコーポレイテッド | Ｎａｐｉ２ｂ標的化療法に対する応答を予測するための組成物および方法 |
| US20210040205A1 (en) | 2017-10-25 | 2021-02-11 | Novartis Ag | Antibodies targeting cd32b and methods of use thereof |
| MX2020004756A (es) | 2017-11-16 | 2020-08-20 | Novartis Ag | Terapias de combinacion. |
| CN110357958A (zh) | 2018-03-26 | 2019-10-22 | 信达生物制药(苏州)有限公司 | 抗糖皮质激素诱导的肿瘤坏死因子受体(gitr)的小型化抗体、其聚合物及应用 |
| US20210147547A1 (en) | 2018-04-13 | 2021-05-20 | Novartis Ag | Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof |
| KR20210016562A (ko) | 2018-05-23 | 2021-02-16 | 에이디씨 테라퓨틱스 에스에이 | 분자 애쥬번트 |
| US20210214459A1 (en) | 2018-05-31 | 2021-07-15 | Novartis Ag | Antibody molecules to cd73 and uses thereof |
| BR112020026947B1 (pt) | 2018-07-10 | 2022-11-22 | Novartis Ag | Derivados de 3-(5-hidróxi-1-oxoisoindolin-2-il)piperidina-2,6-diona, e composição farmacêutica |
| AR116109A1 (es) | 2018-07-10 | 2021-03-31 | Novartis Ag | Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos |
| WO2020021465A1 (en) | 2018-07-25 | 2020-01-30 | Advanced Accelerator Applications (Italy) S.R.L. | Method of treatment of neuroendocrine tumors |
| WO2020089811A1 (en) | 2018-10-31 | 2020-05-07 | Novartis Ag | Dc-sign antibody drug conjugates |
| BR112021011874A2 (pt) | 2018-12-20 | 2021-09-08 | Novartis Ag | Regime de dosagem e combinação farmacêutica compreendendo derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona |
| CA3119584A1 (en) | 2018-12-21 | 2020-06-25 | Novartis Ag | Use of il-1 beta antibodies in the treatment or prevention of myelodysplastic syndrome |
| WO2020128613A1 (en) | 2018-12-21 | 2020-06-25 | Novartis Ag | Use of il-1beta binding antibodies |
| CA3119582A1 (en) | 2018-12-21 | 2020-06-25 | Novartis Ag | Use of il-1.beta. binding antibodies |
| WO2020128637A1 (en) | 2018-12-21 | 2020-06-25 | Novartis Ag | Use of il-1 binding antibodies in the treatment of a msi-h cancer |
| WO2020165833A1 (en) | 2019-02-15 | 2020-08-20 | Novartis Ag | 3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof |
| AU2020222346B2 (en) | 2019-02-15 | 2021-12-09 | Novartis Ag | Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof |
| JP2022553306A (ja) | 2019-10-21 | 2022-12-22 | ノバルティス アーゲー | Ｔｉｍ－３阻害剤およびその使用 |
| CN114786679A (zh) | 2019-10-21 | 2022-07-22 | 诺华股份有限公司 | 具有维奈托克和tim-3抑制剂的组合疗法 |
| GB201917254D0 (en) | 2019-11-27 | 2020-01-08 | Adc Therapeutics Sa | Combination therapy |
| CN115175937A (zh) | 2019-12-20 | 2022-10-11 | 诺华股份有限公司 | 用于治疗骨髓纤维化和骨髓增生异常综合征的抗TIM-3抗体MBG453和抗TGF-β抗体NIS793与或不与地西他滨或抗PD-1抗体斯巴达珠单抗的组合 |
| KR20220128389A (ko) | 2020-01-17 | 2022-09-20 | 노파르티스 아게 | 골수이형성 증후군 또는 만성 골수단핵구성 백혈병을 치료하는데 사용하기 위한 tim-3 억제제 및 저메틸화제를 포함하는 조합물 |
| KR20230024967A (ko) | 2020-06-11 | 2023-02-21 | 노파르티스 아게 | Zbtb32 억제제 및 이의 용도 |
| CA3182346A1 (en) | 2020-06-23 | 2021-12-30 | Novartis Ag | Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives |
| US20230271940A1 (en) | 2020-08-03 | 2023-08-31 | Novartis Ag | Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof |
| US20230321285A1 (en) | 2020-08-31 | 2023-10-12 | Advanced Accelerator Applications International Sa | Method of treating psma-expressing cancers |
| EP4204020A1 (en) | 2020-08-31 | 2023-07-05 | Advanced Accelerator Applications International S.A. | Method of treating psma-expressing cancers |
| GB202102396D0 (en) | 2021-02-19 | 2021-04-07 | Adc Therapeutics Sa | Molecular adjuvant |
| TW202304979A (zh) | 2021-04-07 | 2023-02-01 | 瑞士商諾華公司 | 抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途 |
| AR125874A1 (es) | 2021-05-18 | 2023-08-23 | Novartis Ag | Terapias de combinación |
| EP4493195A1 (en) | 2022-03-15 | 2025-01-22 | Compugen Ltd. | Il-18bp antagonist antibodies and their use in monotherapy and combination therapy in the treatment of cancer |
| TW202515608A (zh) | 2023-06-26 | 2025-04-16 | 以色列商坎布根有限公司 | Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途 |
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-
2016
- 2016-06-02 ES ES16731700T patent/ES2810856T3/es active Active
- 2016-06-02 CA CA2988115A patent/CA2988115A1/en not_active Abandoned
- 2016-06-02 MX MX2017015260A patent/MX2017015260A/es unknown
- 2016-06-02 US US15/578,874 patent/US10690674B2/en active Active
- 2016-06-02 WO PCT/US2016/035514 patent/WO2016196792A1/en not_active Ceased
- 2016-06-02 JP JP2017562628A patent/JP6812364B2/ja not_active Expired - Fee Related
- 2016-06-02 EP EP16731700.7A patent/EP3304079B1/en not_active Not-in-force
- 2016-06-02 EA EA201792497A patent/EA201792497A1/ru unknown
- 2016-06-02 BR BR112017025297-0A patent/BR112017025297A2/pt not_active Application Discontinuation
- 2016-06-02 CN CN201680032362.6A patent/CN107743586B/zh not_active Expired - Fee Related
-
2020
- 2020-05-08 US US16/870,006 patent/US11408889B2/en active Active
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