JP2018517774A - ニコチンアミドリボシドおよびプテロスチルベン組成物ならびに皮膚障害の処置のための方法 - Google Patents

ニコチンアミドリボシドおよびプテロスチルベン組成物ならびに皮膚障害の処置のための方法 Download PDF

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Publication number
JP2018517774A
JP2018517774A JP2018517123A JP2018517123A JP2018517774A JP 2018517774 A JP2018517774 A JP 2018517774A JP 2018517123 A JP2018517123 A JP 2018517123A JP 2018517123 A JP2018517123 A JP 2018517123A JP 2018517774 A JP2018517774 A JP 2018517774A
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JP
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Prior art keywords
therapeutically effective
effective amount
nicotinamide riboside
per day
pterostilbene
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Pending
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JP2018517123A
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English (en)
Japanese (ja)
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JP2018517774A5 (enExample
Inventor
マルコチュリ，エリック・アレグザンダー
グアレンテ，レナード・パーシング
アルミナナ，ダニエル・アントニオ
ボーエン，ポール・マイケル
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エリジウム・ヘルス・インコーポレイテッド
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Publication of JP2018517774A publication Critical patent/JP2018517774A/ja
Publication of JP2018517774A5 publication Critical patent/JP2018517774A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/673—Vitamin B group
    • A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2018517123A 2015-06-10 2016-02-25 ニコチンアミドリボシドおよびプテロスチルベン組成物ならびに皮膚障害の処置のための方法 Pending JP2018517774A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562173733P 2015-06-10 2015-06-10
US62/173,733 2015-06-10
PCT/US2016/019653 WO2016200447A1 (en) 2015-06-10 2016-02-25 Nicotinamide riboside and pterostilbene compositions and methods for treatment of skin disorders

Publications (2)

Publication Number Publication Date
JP2018517774A true JP2018517774A (ja) 2018-07-05
JP2018517774A5 JP2018517774A5 (enExample) 2019-04-04

Family

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JP2018517123A Pending JP2018517774A (ja) 2015-06-10 2016-02-25 ニコチンアミドリボシドおよびプテロスチルベン組成物ならびに皮膚障害の処置のための方法

Country Status (13)

Country Link
US (2) US11426398B2 (enExample)
EP (1) EP3307754B1 (enExample)
JP (1) JP2018517774A (enExample)
KR (1) KR20180021784A (enExample)
CN (1) CN107849083A (enExample)
AU (2) AU2016274126A1 (enExample)
CA (1) CA2989115C (enExample)
ES (1) ES2932801T3 (enExample)
MX (2) MX389207B (enExample)
RU (1) RU2017145692A (enExample)
TW (1) TWI725033B (enExample)
WO (1) WO2016200447A1 (enExample)
ZA (1) ZA201800056B (enExample)

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AU2016274126A1 (en) 2015-06-10 2018-01-18 Elysium Health, Inc. Nicotinamide riboside and pterostilbene compositions and methods for treatment of skin disorders
US20180325931A1 (en) 2017-01-21 2018-11-15 Ningbo Zhiming Biotechnology Co., Ltd. Use of paeoniflorin-6'-o-benzenesulfonate in treatment of sjögren's syndrome
ES3014265T3 (en) 2017-03-17 2025-04-21 Elysium Health Inc Combination of nicotinamide riboside and pterostilbene for use in treating or preventing liver damage
JP2020517736A (ja) * 2017-04-24 2020-06-18 エリシウム ヘルス，インコーポレーテッド 腎臓損傷の治療及び予防
JP7143402B2 (ja) * 2017-05-17 2022-09-28 ウニベルシタ デ バレンシア－エストゥディ ヘネラル ニコチンアミドリボシドを使用する運動ニューロン疾患の治療及び予防
WO2018213715A1 (en) * 2017-05-18 2018-11-22 Elysium Health, Inc. Methods and compositions for improving sleep
CN111542312A (zh) * 2017-07-28 2020-08-14 老龄化控制中心股份公司 预防和逆转衰老方面的组合物和方法
CN109589309A (zh) * 2017-09-30 2019-04-09 浙江嘉华化工有限公司 烟酰胺核糖微囊的制备方法
CN111601814A (zh) * 2017-10-19 2020-08-28 益力舒健康公司 Tdp-43相关疾病的预防和治疗
US20210186996A1 (en) * 2017-12-01 2021-06-24 Elysium Health, Inc. Methods and compositions for treating multiple sclerosis
WO2019108875A1 (en) * 2017-12-01 2019-06-06 Elysium Health, Inc. Methods and compositions for treating glaucoma
GB201811312D0 (en) * 2018-07-10 2018-08-29 Nuchido Ltd Compositions
SG11202102204PA (en) 2018-09-25 2021-04-29 Ponce De Leon Health Designated Activity Company Process of making calcium alpha-ketoglutarate
CN111569084B (zh) * 2019-02-19 2021-07-13 中国科学院上海药物研究所 基于柳胺酚和紫檀芪的成环偶联分子dcz0801类化合物、其制备方法及用途
WO2020176445A1 (en) * 2019-02-26 2020-09-03 Universitat De Valencia-Estudi General Methods and compositions for treating motor neuron diseases
WO2020190703A1 (en) * 2019-03-21 2020-09-24 Elysium Health, Inc. Methods for wound treatment
CN113768946A (zh) * 2020-05-25 2021-12-10 南京帝昌医药科技有限公司 一种治疗糖尿病皮肤并发症的软膏及其制备方法
CN113712193A (zh) * 2020-05-25 2021-11-30 南京帝昌医药科技有限公司 修复皮肤系统的组合物制备方法及其用途
US20230270770A1 (en) * 2020-07-30 2023-08-31 Moises HERNANDEZ-VAZQUEZ Nutritional supplements for repairing muscle and defending against deterioration from human aging
EP4380577A1 (en) * 2021-08-02 2024-06-12 Nuvamid SA Nicotinamide mononucleotide derivatives for use in the treatment of sapho syndrome
WO2023119230A1 (en) 2021-12-22 2023-06-29 L'oreal Coagulation pathway and nicotinamide-adenine dinucleotide pathway modulating compositions and methods of their use

Citations (2)

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JP2013509385A (ja) * 2009-10-30 2013-03-14 グリーン モールキュラー，エス．エル 皮膚の疾患、傷害または損傷の予防および／または処置における使用のためのプテロスチルベン（ｐｔｅｒ）
WO2015066382A1 (en) * 2013-10-30 2015-05-07 ChromaDex Inc. Nicotinamide riboside compositions for topical use in treating skin conditions

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ES2670927T3 (es) * 2005-11-18 2018-06-04 Cornell Research Foundation, Inc. Composiciones de nicotinoil ribósido y métodos de uso
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WO2015066382A1 (en) * 2013-10-30 2015-05-07 ChromaDex Inc. Nicotinamide riboside compositions for topical use in treating skin conditions
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Also Published As

Publication number Publication date
AU2020286208A1 (en) 2021-01-07
RU2017145692A (ru) 2019-07-10
AU2016274126A1 (en) 2018-01-18
CN107849083A (zh) 2018-03-27
EP3307754A1 (en) 2018-04-18
TW201713322A (zh) 2017-04-16
MX2021012600A (es) 2021-11-12
EP3307754B1 (en) 2022-09-14
CA2989115C (en) 2024-01-02
CA2989115A1 (en) 2016-12-15
US12109206B2 (en) 2024-10-08
RU2017145692A3 (enExample) 2019-07-31
MX2017016024A (es) 2018-08-15
KR20180021784A (ko) 2018-03-05
US20180353497A1 (en) 2018-12-13
EP3307754A4 (en) 2019-03-27
WO2016200447A1 (en) 2016-12-15
US11426398B2 (en) 2022-08-30
MX389207B (es) 2025-03-20
TWI725033B (zh) 2021-04-21
US20220362233A1 (en) 2022-11-17
ZA201800056B (en) 2023-10-25
AU2020286208B2 (en) 2022-11-10
ES2932801T3 (es) 2023-01-26

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