JP2018516978A5 - - Google Patents
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- JP2018516978A5 JP2018516978A5 JP2018511592A JP2018511592A JP2018516978A5 JP 2018516978 A5 JP2018516978 A5 JP 2018516978A5 JP 2018511592 A JP2018511592 A JP 2018511592A JP 2018511592 A JP2018511592 A JP 2018511592A JP 2018516978 A5 JP2018516978 A5 JP 2018516978A5
- Authority
- JP
- Japan
- Prior art keywords
- guide rna
- cas
- cas protein
- mutation
- promoter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021189812A JP2022031769A (ja) | 2015-05-16 | 2021-11-24 | 深部イントロン突然変異の遺伝子編集 |
| JP2024038537A JP7814430B2 (ja) | 2015-05-16 | 2024-03-13 | 深部イントロン突然変異の遺伝子編集 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562162720P | 2015-05-16 | 2015-05-16 | |
| US62/162,720 | 2015-05-16 | ||
| PCT/US2016/027987 WO2016186772A2 (en) | 2015-05-16 | 2016-04-15 | Gene editing of deep intronic mutations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021189812A Division JP2022031769A (ja) | 2015-05-16 | 2021-11-24 | 深部イントロン突然変異の遺伝子編集 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018516978A JP2018516978A (ja) | 2018-06-28 |
| JP2018516978A5 true JP2018516978A5 (https=) | 2019-05-23 |
| JP6985250B2 JP6985250B2 (ja) | 2021-12-22 |
Family
ID=55809259
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018511592A Active JP6985250B2 (ja) | 2015-05-16 | 2016-04-15 | 深部イントロン突然変異の遺伝子編集 |
| JP2021189812A Pending JP2022031769A (ja) | 2015-05-16 | 2021-11-24 | 深部イントロン突然変異の遺伝子編集 |
| JP2024038537A Active JP7814430B2 (ja) | 2015-05-16 | 2024-03-13 | 深部イントロン突然変異の遺伝子編集 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021189812A Pending JP2022031769A (ja) | 2015-05-16 | 2021-11-24 | 深部イントロン突然変異の遺伝子編集 |
| JP2024038537A Active JP7814430B2 (ja) | 2015-05-16 | 2024-03-13 | 深部イントロン突然変異の遺伝子編集 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11896651B2 (https=) |
| EP (1) | EP3298134B8 (https=) |
| JP (3) | JP6985250B2 (https=) |
| KR (2) | KR20230142649A (https=) |
| CN (3) | CN107849547B (https=) |
| AU (2) | AU2016265255B2 (https=) |
| BR (1) | BR112017024514A2 (https=) |
| CA (1) | CA2986021A1 (https=) |
| ES (1) | ES2952598T3 (https=) |
| IL (2) | IL296365A (https=) |
| MX (2) | MX2017014665A (https=) |
| PL (1) | PL3298134T3 (https=) |
| PT (1) | PT3298134T (https=) |
| RU (2) | RU2759335C2 (https=) |
| SG (2) | SG10201910750WA (https=) |
| WO (1) | WO2016186772A2 (https=) |
Families Citing this family (77)
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| JP6261500B2 (ja) | 2011-07-22 | 2018-01-17 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ヌクレアーゼ切断特異性の評価および改善 |
| US20150044192A1 (en) | 2013-08-09 | 2015-02-12 | President And Fellows Of Harvard College | Methods for identifying a target site of a cas9 nuclease |
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| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| US20150165054A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting caspase-9 point mutations |
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-
2016
- 2016-04-15 WO PCT/US2016/027987 patent/WO2016186772A2/en not_active Ceased
- 2016-04-15 PT PT167188408T patent/PT3298134T/pt unknown
- 2016-04-15 AU AU2016265255A patent/AU2016265255B2/en active Active
- 2016-04-15 RU RU2017143997A patent/RU2759335C2/ru active
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