JP2018506287A5 - - Google Patents

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Publication number
JP2018506287A5
JP2018506287A5 JP2017542910A JP2017542910A JP2018506287A5 JP 2018506287 A5 JP2018506287 A5 JP 2018506287A5 JP 2017542910 A JP2017542910 A JP 2017542910A JP 2017542910 A JP2017542910 A JP 2017542910A JP 2018506287 A5 JP2018506287 A5 JP 2018506287A5
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JP
Japan
Prior art keywords
tcr
cells
purified
chain
nucleic acid
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Application number
JP2017542910A
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English (en)
Japanese (ja)
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JP2018506287A (ja
JP7013240B2 (ja
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Priority claimed from PCT/US2016/017521 external-priority patent/WO2016133779A1/en
Publication of JP2018506287A publication Critical patent/JP2018506287A/ja
Publication of JP2018506287A5 publication Critical patent/JP2018506287A5/ja
Priority to JP2022006072A priority Critical patent/JP7317158B2/ja
Application granted granted Critical
Publication of JP7013240B2 publication Critical patent/JP7013240B2/ja
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JP2017542910A 2015-02-16 2016-02-11 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体 Active JP7013240B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022006072A JP7317158B2 (ja) 2015-02-16 2022-01-19 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562116864P 2015-02-16 2015-02-16
US62/116,864 2015-02-16
PCT/US2016/017521 WO2016133779A1 (en) 2015-02-16 2016-02-11 A fully-human t cell receptor specific for the 369-377 epitope derived from the her2/neu (erbb2) receptor protein

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022006072A Division JP7317158B2 (ja) 2015-02-16 2022-01-19 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体

Publications (3)

Publication Number Publication Date
JP2018506287A JP2018506287A (ja) 2018-03-08
JP2018506287A5 true JP2018506287A5 (https=) 2019-03-22
JP7013240B2 JP7013240B2 (ja) 2022-01-31

Family

ID=56692400

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017542910A Active JP7013240B2 (ja) 2015-02-16 2016-02-11 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体
JP2022006072A Active JP7317158B2 (ja) 2015-02-16 2022-01-19 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022006072A Active JP7317158B2 (ja) 2015-02-16 2022-01-19 Ｈｅｒ２／Ｎｅｕ （ＥＲＢＢ２）受容体タンパク質に由来する３６９～３７７位エピトープに特異的な完全ヒトＴ細胞受容体

Country Status (6)

Country Link
US (4) US10414812B2 (https=)
EP (2) EP3259284B1 (https=)
JP (2) JP7013240B2 (https=)
AU (4) AU2016220324B2 (https=)
CA (1) CA2976656A1 (https=)
WO (1) WO2016133779A1 (https=)

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Publication number Priority date Publication date Assignee Title
GB2592821B (en) 2015-07-31 2022-01-12 Univ Minnesota Modified cells and methods of therapy
WO2018065623A2 (en) 2016-10-07 2018-04-12 Enterome Immunogenic compounds for cancer therapy
EP3645021A4 (en) 2017-06-30 2021-04-21 Intima Bioscience, Inc. ADENO-ASSOCIATED VIRAL VECTORS FOR GENE THERAPY
CN109776671B (zh) * 2017-11-14 2022-05-27 杭州康万达医药科技有限公司 分离的t细胞受体、其修饰的细胞、编码核酸、表达载体、制备方法、药物组合物和应用
JP7436383B2 (ja) 2018-04-18 2024-02-21 ユーシーエル ビジネス リミテッド 操作された調節性ｔ細胞
WO2019241315A1 (en) 2018-06-12 2019-12-19 Obsidian Therapeutics, Inc. Pde5 derived regulatory constructs and methods of use in immunotherapy
CN110857319B (zh) * 2018-08-24 2023-12-08 杭州康万达医药科技有限公司 一种分离的t细胞受体、其修饰的细胞、编码核酸及其应用
WO2021079122A1 (en) * 2019-10-23 2021-04-29 Ucl Business Ltd Engineered regulatory t cell

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US1975A (en) 1841-02-12 Manner of constructing corn-shellers
US4694778A (en) 1984-05-04 1987-09-22 Anicon, Inc. Chemical vapor deposition wafer boat
US5585362A (en) 1989-08-22 1996-12-17 The Regents Of The University Of Michigan Adenovirus vectors for gene therapy
GB9125768D0 (en) 1991-12-04 1992-02-05 Hale Geoffrey Therapeutic method
US6080840A (en) 1992-01-17 2000-06-27 Slanetz; Alfred E. Soluble T cell receptors
US5350674A (en) 1992-09-04 1994-09-27 Becton, Dickinson And Company Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof
WO1995004521A1 (en) 1993-08-10 1995-02-16 W.L. Gore & Associates, Inc. Cell encapsulating device
US5626561A (en) 1995-06-07 1997-05-06 Gore Hybrid Technologies, Inc. Implantable containment apparatus for a therapeutical device and method for loading and reloading the device therein
WO1996039993A1 (en) 1995-06-07 1996-12-19 Gore Hybrid Technologies, Inc. An implantable containment apparatus for a therapeutical device and method for loading and reloading the device therein
WO1997010807A1 (en) 1995-09-22 1997-03-27 Gore Hybrid Technologies, Inc. Improved cell encapsulation device
CA2246333A1 (en) * 1996-03-05 1997-09-12 The Scripps Research Institute Recombinant constructs encoding t cell receptors specific for human hla-restricted tumor antigens
FR2827302B1 (fr) * 2001-07-13 2003-10-10 Genoway Cellule et animal transgenique modelisant la presentation antigenique humaine et leurs utilisations
US7213961B2 (en) 2003-07-11 2007-05-08 Hubbell Incorporated Low voltage luminaire assembly
EP1938104A2 (en) * 2005-10-17 2008-07-02 Institute for Systems Biology Tissue-and serum-derived glycoproteins and methods of their use
WO2010012829A1 (en) * 2008-07-31 2010-02-04 Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Her2/neu specific t cell receptors
WO2010089412A1 (en) * 2009-02-09 2010-08-12 Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt (Gmbh) Repertoire of allo-restricted peptide-specific t cell receptor sequences and use thereof
HRP20171164T1 (hr) * 2010-09-20 2017-10-20 Biontech Cell & Gene Therapies Gmbh Antigen-specifični t stanični receptori i t stanični epitopi
TR201905447T4 (tr) 2012-12-14 2019-05-21 Biontech Rna Pharmaceuticals Gmbh Yeni mhc bağımsız tümörle ilişkili antijenler.

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