JP2018505187A5 - - Google Patents

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Publication number
JP2018505187A5
JP2018505187A5 JP2017540788A JP2017540788A JP2018505187A5 JP 2018505187 A5 JP2018505187 A5 JP 2018505187A5 JP 2017540788 A JP2017540788 A JP 2017540788A JP 2017540788 A JP2017540788 A JP 2017540788A JP 2018505187 A5 JP2018505187 A5 JP 2018505187A5
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JP
Japan
Prior art keywords
cxcr4 antagonists
composition according
release
pharmaceutical composition
cxcr4
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017540788A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018505187A (ja
JP7127988B2 (ja
Filing date
Publication date
Priority claimed from EP15152886.6A external-priority patent/EP3050574B1/en
Application filed filed Critical
Publication of JP2018505187A publication Critical patent/JP2018505187A/ja
Publication of JP2018505187A5 publication Critical patent/JP2018505187A5/ja
Application granted granted Critical
Publication of JP7127988B2 publication Critical patent/JP7127988B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017540788A 2015-01-28 2016-01-28 新規な組成物ならびに慢性閉塞性肺疾患を処置および/または予防する方法 Active JP7127988B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15152886.6A EP3050574B1 (en) 2015-01-28 2015-01-28 Use of plerixafor for treating and/or preventing acute exacerbations of chronic obstructive pulmonary disease
EP15152886.6 2015-01-28
PCT/EP2016/051771 WO2016120369A1 (en) 2015-01-28 2016-01-28 New compositions and methods of treating and/or preventing chronic obstructive pulmonary disease

Publications (3)

Publication Number Publication Date
JP2018505187A JP2018505187A (ja) 2018-02-22
JP2018505187A5 true JP2018505187A5 (enExample) 2022-05-30
JP7127988B2 JP7127988B2 (ja) 2022-08-30

Family

ID=52434596

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017540788A Active JP7127988B2 (ja) 2015-01-28 2016-01-28 新規な組成物ならびに慢性閉塞性肺疾患を処置および/または予防する方法

Country Status (12)

Country Link
US (1) US10813911B2 (enExample)
EP (2) EP3050574B1 (enExample)
JP (1) JP7127988B2 (enExample)
CN (1) CN107405405B (enExample)
AU (1) AU2016212067B2 (enExample)
BR (1) BR112017016347A2 (enExample)
CA (1) CA2972319C (enExample)
DK (1) DK3050574T3 (enExample)
EA (1) EA201791689A1 (enExample)
ES (1) ES2764840T3 (enExample)
IL (1) IL253688B2 (enExample)
WO (1) WO2016120369A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017127810A1 (en) * 2016-01-22 2017-07-27 Indiana University Research & Technology Corporation Methods for repairing lung tissue
TWI734027B (zh) * 2017-09-18 2021-07-21 泰宗生物科技股份有限公司 用於治療癌症之組合物
EP4085910A1 (en) * 2021-05-05 2022-11-09 4Living Biotech Use of a compound such as plerixafor for treating a viral pulmonary disease
CN119925562B (zh) * 2023-11-03 2025-11-28 中国科学院上海药物研究所 趋化因子受体2拮抗剂在制备治疗糖尿病并发焦虑症的应用
KR20250133491A (ko) * 2024-02-28 2025-09-08 재단법인 오송첨단의료산업진흥재단 인간 ccl7에 결합하는 신규한 항체 및 이의 용도
CN118252937B (zh) * 2024-04-07 2024-10-22 中山大学 Cxcr4受体的拮抗剂在抗埃博拉病毒感染中的应用

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
US5840867A (en) 1991-02-21 1998-11-24 Gilead Sciences, Inc. Aptamer analogs specific for biomolecules
GB9126677D0 (en) 1991-12-16 1992-02-12 Johnson Matthey Plc Improvements in chemical compounds
ATE344324T1 (de) 1993-09-14 2006-11-15 Imp Innovations Ltd Eotaxin = eosinophil chemotaktisches cytokin
JP3367581B2 (ja) 1993-10-14 2003-01-14 小野薬品工業株式会社 新規なポリペプチド、その製造方法、そのポリペプチドをコードするdna、そのdnaからなるベクター、そのベクターで形質転換された宿主細胞
US6806061B1 (en) 1995-01-19 2004-10-19 Children's Medical Center Corporation G protein-coupled receptor gene and methods of use therefor
US6699843B2 (en) 1995-06-07 2004-03-02 Gilead Sciences, Inc. Method for treatment of tumors using nucleic acid ligands to PDGF
WO1997024325A1 (en) 1995-12-28 1997-07-10 Takeda Chemical Industries, Ltd. DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS
EP0914319B1 (en) 1996-05-20 2001-11-21 Teijin Limited Diarylalkyl cyclic diamine derivatives as chemokine receptor antagonists
AU6133098A (en) 1997-01-21 1998-08-07 Merck & Co., Inc. 3,3-disubstituted piperidines as modulators of chemokine receptor activity
SK112899A3 (en) 1997-02-26 2001-05-10 Pfizer Heteroaryl-hexanoic acid amide derivatives, their preparation and their use as selective inhibitors of mip-1-alpha binding to its ccr1 receptor
US6207155B1 (en) 1997-05-07 2001-03-27 Schering Corporation Method of eosinophil depletion with antibody to CCR 3 receptor
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
WO1999036518A1 (en) 1998-01-15 1999-07-22 Btg International Limited Ribozymal nucleic acids cleaving ccr5 or cxcr4
CA2321962C (en) 1998-02-27 2014-07-15 The Government Of The United States Of America, Represented By The Secretary Of The Department Of Health And Human Services G protein-coupled receptor antagonists
US6180348B1 (en) 1998-04-20 2001-01-30 Weihua Li Method of isolating target specific oligonucleotide ligands
CA2235420A1 (en) 1998-06-17 1999-12-17 Paolo Renzi Antisense oligonucleotides for treating or preventing atopic diseases and neoplastic cell proliferation
US6429308B1 (en) 1998-11-24 2002-08-06 Hisamitsu Pharmaceutical Co., Inc. HIV infection inhibitors
US6723538B2 (en) 1999-03-11 2004-04-20 Micromet Ag Bispecific antibody and chemokine receptor constructs
IL145401A0 (en) 1999-03-24 2002-06-30 Anormed Inc Chemokine receptor binding heterocyclic compounds
AU2001233277B2 (en) 2000-02-03 2004-06-03 Millennium Pharmaceuticals, Inc. Humanized anti-ccr2 antibodies and methods of use therefor
GB2361704C (en) 2000-03-03 2006-08-02 Cambridge Antibody Tech Human antibodies against eotaxin and their use
US6946546B2 (en) 2000-03-06 2005-09-20 Cambridge Antibody Technology Limited Human antibodies against eotaxin
GB0016138D0 (en) 2000-06-30 2000-08-23 Novartis Ag Organic compounds
US20020147312A1 (en) 2001-02-02 2002-10-10 O'keefe Theresa Hybrid antibodies and uses thereof
US20050124569A1 (en) 2001-05-18 2005-06-09 Sirna Therapeutics, Inc. RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA)
EP2990394A1 (en) 2001-11-30 2016-03-02 Biogen MA Inc. Antibodies against monocyte chemotactic proteins
AR041786A1 (es) 2002-03-15 2005-06-01 Novartis Ag Derivados de azetidina como antagonistas del receptor ccr-3, un proceso para su preparacion, una composicion farmaceutica y el uso de dichos derivados para la elaboracion de un medicamento
GB0212357D0 (en) 2002-05-29 2002-07-10 Glaxo Group Ltd Novel compounds
JP2006502107A (ja) 2002-07-02 2006-01-19 エフ.ホフマン−ラ ロシュ アーゲー Ccr−3レセプターアンタゴニストixとしての2,5−置換ピリミジン誘導体
US7964194B2 (en) 2002-11-15 2011-06-21 Morehouse School Of Medicine Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation
PL378753A1 (pl) 2003-02-27 2006-05-15 F.Hoffmann-La Roche Ag Antagoniści receptora CCR-3
US20050069955A1 (en) 2003-06-30 2005-03-31 Daniel Plaksin Antibodies and uses thereof
AR046594A1 (es) 2003-10-16 2005-12-14 Applied Research Systems Usos terapeuticos de variantes de quemoquina
AU2005214287A1 (en) 2004-02-20 2005-09-01 Genesis Research And Development Corporation Limited Targeted delivery of RNA interference molecules for the treatment of IgE-mediated disorders
ATE425161T1 (de) 2004-05-26 2009-03-15 Janssen Pharmaceutica Nv Mercaptoimidazole als ccr2-rezeptorantagonisten
KR20070063562A (ko) 2004-09-28 2007-06-19 얀센 파마슈티카 엔.브이. 치환 디피페리딘 ccr2 길항제
AU2006203826A1 (en) 2005-01-07 2006-07-13 Emory University CXCR4 antagonists for the treatment of HIV infection
US7622583B2 (en) 2005-01-14 2009-11-24 Chemocentryx, Inc. Heteroaryl sulfonamides and CCR2
TW200716174A (en) 2005-05-19 2007-05-01 Centocor Inc Anti-MCP-1 antibodies, compositions, methods and uses
GB0517966D0 (en) 2005-09-02 2005-10-12 Novartis Ag Organic compounds
HUP0500877A2 (en) 2005-09-22 2007-05-29 Sanofi Aventis Amide derivatives as ccr3 receptor ligands, process for producing them, pharmaceutical compositions containing them and their use and intermediates
EP2041568A4 (en) 2006-06-15 2009-08-12 CCR2 ANTAGONISTS FOR CHRONIC BREATHING REACTIONS IN ORGAN TRANSPLANTATIONS
ATE537166T1 (de) 2006-10-27 2011-12-15 Boehringer Ingelheim Int Piperidylpropanthiole als ccr3-modulatoren
HRP20110551T1 (hr) 2007-05-30 2011-09-30 Eli Lilly & Company Antagonisti cikličkog peptida cxcr4
CA2692761C (en) 2007-07-12 2013-04-30 Chemocentryx, Inc. Fused heteroaryl pyridyl and phenyl benzenesulfonamides as ccr2 modulators for the treament of inflammation
EP2237798A2 (en) * 2007-12-12 2010-10-13 Imperial Innovations Limited Methods
HUP0800478A2 (en) 2008-07-31 2010-03-01 Sanofi Aventis Substituted pyrrolidinyl-[1,3]thiazolo[4,5-b]pyridin derivatives as ccr3 receptor ligands
WO2010069979A1 (en) 2008-12-16 2010-06-24 Nycomed Gmbh Pyran derivatives as ccr3 modulators
ES2551557T3 (es) 2008-12-19 2015-11-19 Boehringer Ingelheim International Gmbh Pirimidin-4-carboxamidas cíclicas como antagonistas del receptor CCR2 para el tratamiento de inflamaciones, asma y EPOC
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
ES2528625T3 (es) 2009-04-17 2015-02-11 Janssen Pharmaceutica Nv Antagonistas de 4-azetidinil-1-fenil-ciclohexano de CCR2
US8471004B2 (en) 2009-10-07 2013-06-25 Hoffman-La Roche Inc. Bicyclic compounds
US8445674B2 (en) 2009-10-21 2013-05-21 Hoffmann-La Roche Inc Heterocyclyl compounds
JP5356323B2 (ja) * 2010-07-01 2013-12-04 富士化学工業株式会社 新規な非晶質ボセンタン及びその製造方法
US20120088769A1 (en) * 2010-10-11 2012-04-12 Axikin Pharmaceuticals, Inc. Salts of arylsulfonamide ccr3 antagonists
EP2646429B1 (en) 2010-12-01 2014-10-15 Janssen Pharmaceutica NV 4-substituted-cyclohexylamino-4-piperidinyl-acetamide antagonists of ccr2
US20140005174A1 (en) 2011-03-17 2014-01-02 Anilkumar G. Nair Indole derivatives useful as ccr2 antagonists
WO2012138880A2 (en) 2011-04-07 2012-10-11 The Brigham And Women's Hospital, Inc. Methods of treating inflammatory diseases by targeting the chemoattractant cytokine receptor 2 (ccr2) or chemokine (c-c motif) ligand 2 (ccl2)
AU2012258575B2 (en) * 2011-05-25 2017-03-02 Intermune, Inc. Pirfenidone and anti-fibrotic therapy in selected patients
DK2723360T3 (en) 2011-06-27 2017-08-28 Univ Pierre Et Marie Curie Paris 6 CCR2 antagonist peptides
US20140336159A1 (en) * 2011-10-07 2014-11-13 Pulmatrix, Inc. Methods for treating and diagnosing respiratory tract infections
WO2013057545A1 (en) * 2011-10-18 2013-04-25 Biocon Limited Acid addition salts of bosentan
US8822460B2 (en) 2012-04-06 2014-09-02 Janssen Pharmaceutica Nv Fused cyclopentyl antagonists of CCR2
US20160015786A1 (en) * 2013-03-01 2016-01-21 Mater Medical Research Institute Limited Mobilizing agents and uses therefor
WO2014143807A2 (en) * 2013-03-15 2014-09-18 Stromatt Scott Anti-cd37 antibody and bcr pathway antagonist combination therapy for treatment of b-cell malignancies and disorders

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