IL253688B2 - New preparations and methods for the treatment or prevention of chronic obstructive pulmonary diseases - Google Patents

New preparations and methods for the treatment or prevention of chronic obstructive pulmonary diseases

Info

Publication number
IL253688B2
IL253688B2 IL253688A IL25368817A IL253688B2 IL 253688 B2 IL253688 B2 IL 253688B2 IL 253688 A IL253688 A IL 253688A IL 25368817 A IL25368817 A IL 25368817A IL 253688 B2 IL253688 B2 IL 253688B2
Authority
IL
Israel
Prior art keywords
cxcr4
ccr2
antagonists
ccr3
copd
Prior art date
Application number
IL253688A
Other languages
English (en)
Hebrew (he)
Other versions
IL253688A (en
IL253688B1 (en
Original Assignee
Univ Bordeaux
Inst Nat Sante Rech Med
Centre Hospitalier Univ Bordeaux
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bordeaux, Inst Nat Sante Rech Med, Centre Hospitalier Univ Bordeaux filed Critical Univ Bordeaux
Publication of IL253688A publication Critical patent/IL253688A/en
Publication of IL253688B1 publication Critical patent/IL253688B1/en
Publication of IL253688B2 publication Critical patent/IL253688B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/715Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
    • G01N2333/7158Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
    • G01N2800/122Chronic or obstructive airway disorders, e.g. asthma COPD
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
IL253688A 2015-01-28 2017-07-27 New preparations and methods for the treatment or prevention of chronic obstructive pulmonary diseases IL253688B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15152886.6A EP3050574B1 (en) 2015-01-28 2015-01-28 Use of plerixafor for treating and/or preventing acute exacerbations of chronic obstructive pulmonary disease
PCT/EP2016/051771 WO2016120369A1 (en) 2015-01-28 2016-01-28 New compositions and methods of treating and/or preventing chronic obstructive pulmonary disease

Publications (3)

Publication Number Publication Date
IL253688A IL253688A (en) 2017-09-28
IL253688B1 IL253688B1 (en) 2023-01-01
IL253688B2 true IL253688B2 (en) 2023-05-01

Family

ID=52434596

Family Applications (1)

Application Number Title Priority Date Filing Date
IL253688A IL253688B2 (en) 2015-01-28 2017-07-27 New preparations and methods for the treatment or prevention of chronic obstructive pulmonary diseases

Country Status (12)

Country Link
US (1) US10813911B2 (enExample)
EP (2) EP3050574B1 (enExample)
JP (1) JP7127988B2 (enExample)
CN (1) CN107405405B (enExample)
AU (1) AU2016212067B2 (enExample)
BR (1) BR112017016347A2 (enExample)
CA (1) CA2972319C (enExample)
DK (1) DK3050574T3 (enExample)
EA (1) EA201791689A1 (enExample)
ES (1) ES2764840T3 (enExample)
IL (1) IL253688B2 (enExample)
WO (1) WO2016120369A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017127810A1 (en) * 2016-01-22 2017-07-27 Indiana University Research & Technology Corporation Methods for repairing lung tissue
TWI734027B (zh) * 2017-09-18 2021-07-21 泰宗生物科技股份有限公司 用於治療癌症之組合物
EP4085910A1 (en) * 2021-05-05 2022-11-09 4Living Biotech Use of a compound such as plerixafor for treating a viral pulmonary disease
CN119925562B (zh) * 2023-11-03 2025-11-28 中国科学院上海药物研究所 趋化因子受体2拮抗剂在制备治疗糖尿病并发焦虑症的应用
KR20250133491A (ko) * 2024-02-28 2025-09-08 재단법인 오송첨단의료산업진흥재단 인간 ccl7에 결합하는 신규한 항체 및 이의 용도
CN118252937B (zh) * 2024-04-07 2024-10-22 中山大学 Cxcr4受体的拮抗剂在抗埃博拉病毒感染中的应用

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Also Published As

Publication number Publication date
US20180271831A1 (en) 2018-09-27
CA2972319C (en) 2023-08-01
IL253688A (en) 2017-09-28
BR112017016347A2 (pt) 2018-03-27
IL253688B1 (en) 2023-01-01
AU2016212067B2 (en) 2020-10-08
EA201791689A1 (ru) 2017-11-30
AU2016212067A1 (en) 2017-09-14
US10813911B2 (en) 2020-10-27
JP2018505187A (ja) 2018-02-22
CA2972319A1 (en) 2016-08-04
CN107405405B (zh) 2021-05-11
EP3050574A1 (en) 2016-08-03
CN107405405A (zh) 2017-11-28
DK3050574T3 (da) 2020-01-20
JP7127988B2 (ja) 2022-08-30
ES2764840T3 (es) 2020-06-04
EP3050574B1 (en) 2019-10-09
WO2016120369A1 (en) 2016-08-04
EP3613435A1 (en) 2020-02-26

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