JP2018504931A5 - - Google Patents
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- Publication number
- JP2018504931A5 JP2018504931A5 JP2017559911A JP2017559911A JP2018504931A5 JP 2018504931 A5 JP2018504931 A5 JP 2018504931A5 JP 2017559911 A JP2017559911 A JP 2017559911A JP 2017559911 A JP2017559911 A JP 2017559911A JP 2018504931 A5 JP2018504931 A5 JP 2018504931A5
- Authority
- JP
- Japan
- Prior art keywords
- bioreactor
- cell culture
- vaccine
- unit
- culture unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000004113 cell culture Methods 0.000 claims 34
- 210000004027 cell Anatomy 0.000 claims 29
- 238000000034 method Methods 0.000 claims 16
- 229960005486 vaccine Drugs 0.000 claims 12
- 239000003570 air Substances 0.000 claims 11
- 239000002609 medium Substances 0.000 claims 9
- 239000012080 ambient air Substances 0.000 claims 8
- 238000012258 culturing Methods 0.000 claims 8
- 239000007789 gas Substances 0.000 claims 8
- 230000010261 cell growth Effects 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 229960000446 abciximab Drugs 0.000 claims 2
- 229960002964 adalimumab Drugs 0.000 claims 2
- 230000003110 anti-inflammatory effect Effects 0.000 claims 2
- 229960004669 basiliximab Drugs 0.000 claims 2
- 210000000170 cell membrane Anatomy 0.000 claims 2
- 230000004700 cellular uptake Effects 0.000 claims 2
- 210000004748 cultured cell Anatomy 0.000 claims 2
- 239000001963 growth medium Substances 0.000 claims 2
- 229960002520 hepatitis vaccine Drugs 0.000 claims 2
- 229960000598 infliximab Drugs 0.000 claims 2
- 229960003971 influenza vaccine Drugs 0.000 claims 2
- 229940041323 measles vaccine Drugs 0.000 claims 2
- 238000002156 mixing Methods 0.000 claims 2
- 229940095293 mumps vaccine Drugs 0.000 claims 2
- 229960000470 omalizumab Drugs 0.000 claims 2
- 229960000402 palivizumab Drugs 0.000 claims 2
- 230000008855 peristalsis Effects 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 229960003127 rabies vaccine Drugs 0.000 claims 2
- 229960003131 rubella vaccine Drugs 0.000 claims 2
- 229940021648 varicella vaccine Drugs 0.000 claims 2
- 229960004854 viral vaccine Drugs 0.000 claims 2
- 239000002699 waste material Substances 0.000 claims 2
- 229960001515 yellow fever vaccine Drugs 0.000 claims 2
- 229920001410 Microfiber Polymers 0.000 claims 1
- 230000006037 cell lysis Effects 0.000 claims 1
- 230000001413 cellular effect Effects 0.000 claims 1
- 238000000502 dialysis Methods 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 238000003306 harvesting Methods 0.000 claims 1
- 239000003658 microfiber Substances 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE2015/5064A BE1022269B1 (fr) | 2015-02-09 | 2015-02-09 | Système, appareil et procédé pour la production de cellules et/ou de produits cellulaires |
| EP2015052633 | 2015-02-09 | ||
| EPPCT/EP2015/052633 | 2015-02-09 | ||
| BEBE2015/5064 | 2015-02-09 | ||
| PCT/EP2016/052644 WO2016128361A1 (en) | 2015-02-09 | 2016-02-08 | System, apparatus and method for the production of cells and/or cell products |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018504931A JP2018504931A (ja) | 2018-02-22 |
| JP2018504931A5 true JP2018504931A5 (enExample) | 2019-05-30 |
| JP6936937B2 JP6936937B2 (ja) | 2021-09-22 |
Family
ID=55310830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017559911A Active JP6936937B2 (ja) | 2015-02-09 | 2016-02-08 | 細胞および／または細胞生成物の製造システム、製造装置および製造方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20180030398A1 (enExample) |
| EP (1) | EP3256565A1 (enExample) |
| JP (1) | JP6936937B2 (enExample) |
| CN (1) | CN107532132A (enExample) |
| AU (1) | AU2016218037B2 (enExample) |
| BR (1) | BR112017016986A2 (enExample) |
| MX (1) | MX2017010217A (enExample) |
| WO (1) | WO2016128361A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012048275A2 (en) | 2010-10-08 | 2012-04-12 | Caridianbct, Inc. | Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
| EP3068866B1 (en) | 2013-11-16 | 2018-04-25 | Terumo BCT, Inc. | Expanding cells in a bioreactor |
| EP3105311A1 (en) * | 2014-02-10 | 2016-12-21 | Univercells NV | System, apparatus and method for biomolecules production |
| US11008547B2 (en) | 2014-03-25 | 2021-05-18 | Terumo Bct, Inc. | Passive replacement of media |
| US20160090569A1 (en) | 2014-09-26 | 2016-03-31 | Terumo Bct, Inc. | Scheduled Feed |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| EP3464565A4 (en) | 2016-05-25 | 2020-01-01 | Terumo BCT, Inc. | CELL EXPANSION |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| BE1024230B1 (fr) | 2016-11-08 | 2017-12-20 | Univercells Sa | Production contenue de cellules et/ou de produits cellulaires |
| CN110612344B (zh) | 2017-03-31 | 2023-09-12 | 泰尔茂比司特公司 | 细胞扩增 |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| US12234441B2 (en) | 2017-03-31 | 2025-02-25 | Terumo Bct, Inc. | Cell expansion |
| RU2020114891A (ru) | 2017-09-27 | 2021-10-27 | Юниверселлс С.А. | Система и способ получения биомолекул, таких как вирусные вакцины |
| JP7057148B2 (ja) * | 2018-01-31 | 2022-04-19 | 株式会社熊谷組 | 微細藻類培養装置 |
| CN110317832B (zh) * | 2018-03-28 | 2022-07-05 | 西比曼生物科技（香港）有限公司 | Gmp级规模化制备重组慢病毒载体的纯化制剂的方法 |
| TWI846694B (zh) * | 2018-05-04 | 2024-07-01 | 美商健臻公司 | 具有過濾系統的灌注式生物反應器 |
| CN112424337A (zh) * | 2018-05-31 | 2021-02-26 | 维格希公司 | 用于分离和纯化多核苷酸的溶胞线圈设备及其用途 |
| GB201810772D0 (en) | 2018-06-29 | 2018-08-15 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
| GB201814233D0 (en) | 2018-08-31 | 2018-10-17 | Ge Healthcare Bio Sciences Ab | Method for optimization of a bioprocessing system |
| WO2020051042A1 (en) * | 2018-09-06 | 2020-03-12 | Momenta Pharmaceuticals, Inc. | Methods of continuous cell culture |
| JP7430717B2 (ja) * | 2018-10-10 | 2024-02-13 | シュタム ヴェーグ コーポレーション | 連続流マイクロバイオリアクター |
| AU2020204794A1 (en) * | 2019-01-04 | 2021-08-12 | Oribiotech Ltd | Cell processing device cell processing system and methods of use thereof |
| US20240093153A1 (en) * | 2019-12-02 | 2024-03-21 | Avant Meats Company Limited | Methods of meat production by in vitro cell cultivation |
| CN112430540A (zh) * | 2020-10-21 | 2021-03-02 | 英诺维尔智能科技（苏州）有限公司 | 一种可置于生物培养箱内的紧凑型反应器 |
| WO2022109071A1 (en) * | 2020-11-18 | 2022-05-27 | Xibus Systems, Inc. | Particle-based detection of analytes |
| GB2619893A (en) | 2021-03-23 | 2023-12-20 | Terumo Bct Inc | Cell capture and expansion |
| WO2022202734A1 (ja) * | 2021-03-26 | 2022-09-29 | テルモ株式会社 | 細胞培養システム |
| KR102870031B1 (ko) * | 2021-09-16 | 2025-11-03 | 주식회사 아모그린텍 | 포터블 바이오리액터 |
| US12209689B2 (en) | 2022-02-28 | 2025-01-28 | Terumo Kabushiki Kaisha | Multiple-tube pinch valve assembly |
| USD1099116S1 (en) | 2022-09-01 | 2025-10-21 | Terumo Bct, Inc. | Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device |
| US12330149B2 (en) * | 2023-10-03 | 2025-06-17 | Ark Biotech Inc. | Mobile bioreactor service system |
| DE102023130768A1 (de) * | 2023-11-07 | 2025-05-08 | KyooBe Tech GmbH | Werkzeugprozesseinheit |
| DE102023130775A1 (de) * | 2023-11-07 | 2025-05-08 | KyooBe Tech GmbH | System und Verfahren zum Rüsten und/oder zum Aufbereiten von Prozesseinheiten zur Herstellung eines Produkts |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58155087A (ja) * | 1982-03-12 | 1983-09-14 | Olympus Optical Co Ltd | 細胞の自動培養装置 |
| US5409841A (en) * | 1991-03-14 | 1995-04-25 | Chow; Timothy | Ultraviolet light sterilized sampling device and method of sampling |
| US5882918A (en) * | 1995-08-08 | 1999-03-16 | Genespan Corporation | Cell culture incubator |
| JPH07236468A (ja) * | 1994-02-28 | 1995-09-12 | Mitsubishi Heavy Ind Ltd | 培養装置 |
| US8026096B1 (en) * | 1998-10-08 | 2011-09-27 | Protein Sciences Corporation | In vivo active erythropoietin produced in insect cells |
| US6214221B1 (en) * | 1999-02-22 | 2001-04-10 | Henry B. Kopf | Method and apparatus for purification of biological substances |
| US8507253B2 (en) * | 2002-05-13 | 2013-08-13 | Algae Systems, LLC | Photobioreactor cell culture systems, methods for preconditioning photosynthetic organisms, and cultures of photosynthetic organisms produced thereby |
| JP2004016194A (ja) * | 2002-06-20 | 2004-01-22 | Hitachi Medical Corp | 細胞培養装置 |
| US7670839B2 (en) * | 2002-12-23 | 2010-03-02 | Fuji Film Manufacturing Europe B.V. | Process for coating cell-culture support |
| US8513848B2 (en) * | 2003-10-09 | 2013-08-20 | Mag Life, Llc | Aquarium having improved filtration system with neutral buoyancy substrate, pump and sediment removal system |
| AU2005209751A1 (en) * | 2004-02-03 | 2005-08-18 | Xcellerex, Inc. | System and method for manufacturing |
| SI1720972T1 (sl) * | 2004-03-05 | 2014-06-30 | Dsm Ip Assets B.V. | Postopek kultiviranja celic s kontinuiranim škropljenjem in spreminjanjem tangencialnega toka |
| AU2013203461B2 (en) * | 2004-03-05 | 2016-03-17 | Patheon Holdings I B.V. | Process for cell culturing by continuous perfusion and alternating tangential flow |
| JP2006174828A (ja) * | 2004-11-29 | 2006-07-06 | Olympus Corp | 生体試料培養観察システム、インキュベータボックス、供給手段、および培養容器 |
| ES2657055T3 (es) * | 2007-08-09 | 2018-03-01 | Wyeth Llc | Uso de perfusión para mejorar la producción de un cultivo de células alimentado por lotes en biorreactores |
| US20090233334A1 (en) * | 2008-03-11 | 2009-09-17 | Excellgene Sa | Cell cultivation and production of recombinant proteins by means of an orbital shake bioreactor system with disposable bags at the 1,500 liter scale |
| CN101821378B (zh) * | 2008-06-16 | 2015-07-08 | 浙江金仪盛世生物工程有限公司 | 生物反应器 |
| JP5341434B2 (ja) * | 2008-08-26 | 2013-11-13 | パナソニックヘルスケア株式会社 | 培養装置 |
| CN201825955U (zh) * | 2009-07-10 | 2011-05-11 | 杭州安普生物工程有限公司 | 一种细胞培养装置 |
| CN101603006B (zh) * | 2009-07-10 | 2012-10-10 | 杭州安普生物工程有限公司 | 一种细胞培养装置 |
| KR20110073949A (ko) * | 2009-12-24 | 2011-06-30 | 연세대학교 산학협력단 | 튜브형 생체조직 또는 생체기관 재생을 위한 세포배양방법 및 세포배양장치 |
| CN102296029B (zh) * | 2010-06-28 | 2013-01-30 | 裴国献 | 灌注式生物反应器系统 |
| CN201915101U (zh) * | 2010-12-20 | 2011-08-03 | 北京清大天一科技有限公司 | 一种动物细胞培养生物反应器 |
| JP5714316B2 (ja) * | 2010-12-22 | 2015-05-07 | 株式会社日立製作所 | 細胞培養装置 |
| US9469671B2 (en) * | 2011-09-03 | 2016-10-18 | Therapeutic Proteins International, LLC | Closed bioreactor |
| SG11201401135XA (en) * | 2011-10-07 | 2014-10-30 | Pall Technology Uk Ltd | Fluid processing control system and related methods |
| DE102012200938B4 (de) * | 2012-01-23 | 2016-08-18 | Alpha Plan Gmbh | Bio- und medizintechnisches Baukastensystem |
| EP2639294A1 (fr) * | 2012-03-15 | 2013-09-18 | CellProthera | Automate et procédé automatisé de culture cellulaire |
| ES2435092B1 (es) * | 2012-06-14 | 2014-09-09 | Aglaris Cell S.L. | Método y sistema de cultivo celular |
| CN103194390B (zh) * | 2013-04-19 | 2014-08-06 | 南方医科大学南方医院 | 双环路振荡灌注式生物反应系统 |
| CN103480276B (zh) * | 2013-09-06 | 2015-09-02 | 北京科兴生物制品有限公司 | 一种封闭式超滤管道系统及其应用 |
| CN103525699B (zh) * | 2013-10-22 | 2015-03-04 | 中国人民解放军第二一〇医院 | 一种细胞暴露特定气体精确控制装置 |
| CN104017727B (zh) * | 2014-06-04 | 2016-03-30 | 奥星制药设备（石家庄）有限公司 | 一次性无菌细胞培养袋配套细胞培养系统 |
| CN107043701A (zh) * | 2017-05-26 | 2017-08-15 | 奥凯（苏州）生物技术有限公司 | 一种提高细胞接种分散性的细胞扩增系统 |
-
2016
- 2016-02-08 JP JP2017559911A patent/JP6936937B2/ja active Active
- 2016-02-08 EP EP16703326.5A patent/EP3256565A1/en not_active Withdrawn
- 2016-02-08 MX MX2017010217A patent/MX2017010217A/es unknown
- 2016-02-08 BR BR112017016986A patent/BR112017016986A2/pt not_active IP Right Cessation
- 2016-02-08 CN CN201680020841.6A patent/CN107532132A/zh active Pending
- 2016-02-08 AU AU2016218037A patent/AU2016218037B2/en active Active
- 2016-02-08 US US15/549,494 patent/US20180030398A1/en not_active Abandoned
- 2016-02-08 WO PCT/EP2016/052644 patent/WO2016128361A1/en not_active Ceased
-
2021
- 2021-06-28 US US17/360,563 patent/US20220017850A1/en active Pending
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