JP2018504919A5 - - Google Patents
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- Publication number
- JP2018504919A5 JP2018504919A5 JP2017548375A JP2017548375A JP2018504919A5 JP 2018504919 A5 JP2018504919 A5 JP 2018504919A5 JP 2017548375 A JP2017548375 A JP 2017548375A JP 2017548375 A JP2017548375 A JP 2017548375A JP 2018504919 A5 JP2018504919 A5 JP 2018504919A5
- Authority
- JP
- Japan
- Prior art keywords
- bacterium
- gene
- bacterium according
- arginine
- wild
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (21)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462087854P | 2014-12-05 | 2014-12-05 | |
| US62/087,854 | 2014-12-05 | ||
| US201562103513P | 2015-01-14 | 2015-01-14 | |
| US62/103,513 | 2015-01-14 | ||
| US201562150508P | 2015-04-21 | 2015-04-21 | |
| US62/150,508 | 2015-04-21 | ||
| US201562173706P | 2015-06-10 | 2015-06-10 | |
| US201562173710P | 2015-06-10 | 2015-06-10 | |
| US62/173,710 | 2015-06-10 | ||
| US62/173,706 | 2015-06-10 | ||
| US201562183935P | 2015-06-24 | 2015-06-24 | |
| US62/183,935 | 2015-06-24 | ||
| US201562184811P | 2015-06-25 | 2015-06-25 | |
| US62/184,811 | 2015-06-25 | ||
| US201562256039P | 2015-11-16 | 2015-11-16 | |
| US201562256041P | 2015-11-16 | 2015-11-16 | |
| US62/256,039 | 2015-11-16 | ||
| US62/256,041 | 2015-11-16 | ||
| US201562263329P | 2015-12-04 | 2015-12-04 | |
| US62/263,329 | 2015-12-04 | ||
| PCT/US2015/064140 WO2016090343A1 (en) | 2014-12-05 | 2015-12-04 | Bacteria engineered to treat diseases associated with hyperammonemia |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018504919A JP2018504919A (ja) | 2018-02-22 |
| JP2018504919A5 true JP2018504919A5 (https=) | 2019-01-24 |
| JP6768689B2 JP6768689B2 (ja) | 2020-10-14 |
Family
ID=55022714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017548375A Expired - Fee Related JP6768689B2 (ja) | 2014-12-05 | 2015-12-04 | 高アンモニア血症に関連する病気を処置するために操作された細菌 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9487764B2 (https=) |
| JP (1) | JP6768689B2 (https=) |
| KR (1) | KR102493174B1 (https=) |
| AU (1) | AU2015357549B2 (https=) |
| BR (1) | BR112017011923A2 (https=) |
| CA (1) | CA2969724A1 (https=) |
| IL (2) | IL252627B (https=) |
| MX (2) | MX383245B (https=) |
| SG (2) | SG11201704543XA (https=) |
| WO (1) | WO2016090343A1 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201704543XA (en) * | 2014-12-05 | 2017-07-28 | Synlogic Inc | Bacteria engineered to treat diseases associated with hyperammonemia |
| US9688967B2 (en) | 2014-12-05 | 2017-06-27 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with hyperammonemia |
| US10610546B2 (en) * | 2015-05-13 | 2020-04-07 | Synlogic Operating Company Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| US20160206666A1 (en) | 2014-12-22 | 2016-07-21 | Synlogic, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tighten gut mucosal barrier |
| US11883439B2 (en) | 2015-05-13 | 2024-01-30 | Synlogic Operating Company, Inc. | Bacteria engineered to treat a disease or disorder |
| WO2016210384A2 (en) | 2015-06-25 | 2016-12-29 | Synlogic, Inc. | Bacteria engineered to treat metabolic diseases |
| US11685925B2 (en) | 2015-10-30 | 2023-06-27 | Synlogic Operating Company, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier |
| WO2017123675A1 (en) | 2016-01-11 | 2017-07-20 | Synlogic, Inc. | Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells |
| WO2017139708A1 (en) | 2016-02-10 | 2017-08-17 | Synlogic, Inc. | Bacteria engineered to treat nonalcoholic steatohepatitis (nash) |
| AU2017252409B2 (en) | 2016-04-20 | 2023-08-24 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for nucleic acid expression and protein secretion in bacteroides |
| WO2018112194A1 (en) | 2016-12-15 | 2018-06-21 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for modulating growth of a genetically modified gut bacterial cell |
| JP2020505016A (ja) | 2017-01-06 | 2020-02-20 | シンロジック オペレーティング カンパニー インコーポレイテッド | 腫瘍細胞において免疫モジュレーターおよび抗がん治療剤を産生するようにプログラムされた微生物 |
| JP2020516318A (ja) * | 2017-04-17 | 2020-06-11 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 操作された共生細菌及び使用方法 |
| CN111655841A (zh) | 2017-06-21 | 2020-09-11 | 同生运营公司 | 用于治疗紊乱的细菌 |
| EP3648769A4 (en) * | 2017-06-30 | 2021-04-07 | The Rockefeller University | HUMAN INTESTINAL FLORA-DERIVED N-ACYLAMIDES FOR THE TREATMENT OF HUMAN DISEASES |
| CN111246865A (zh) * | 2017-07-12 | 2020-06-05 | 同生运营公司 | 程序化以在肿瘤细胞中产生免疫调节剂和抗癌治疗剂的微生物 |
| EP3703705B1 (en) | 2017-11-03 | 2024-05-15 | DSM Nutritional Products, LLC | Glucose-containing glycan preparations for use in the treatment of hyperammonaemia |
| JP7460531B2 (ja) | 2017-12-05 | 2024-04-02 | バイオピーエルエックス，インコーポレイティド | 微生物感染を防ぐための方法および組成物 |
| CA3088630A1 (en) | 2017-12-15 | 2019-06-20 | Solarea Bio, Inc. | Microbial compositions and methods for treating type 2 diabetes, obesity, and metabolic syndrome |
| JP2021525760A (ja) | 2018-06-02 | 2021-09-27 | シンロジック オペレーティング カンパニー インコーポレイテッド | 肝疾患を処置するように操作された細菌 |
| CA3109600A1 (en) | 2018-08-21 | 2020-02-27 | Kaleido Biosciences, Inc. | Oligosaccharide compositions and methods of use thereof for reducing ammonia levels |
| US11980647B2 (en) | 2018-09-05 | 2024-05-14 | Solarea Bio, Inc. | Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause |
| CA3111795A1 (en) | 2018-09-05 | 2020-03-12 | Solarea Bio, Inc. | Methods and compositions for treating musculoskeletal diseases |
| CN113260635B (zh) | 2018-11-08 | 2023-10-31 | Dsm营养产品有限责任公司 | 寡糖组合物及其使用方法 |
| WO2020223345A1 (en) | 2019-04-29 | 2020-11-05 | Antipov Eugene | Enumeration of genetically engineered microorganisms by live cell counting techniques |
| WO2020237246A1 (en) * | 2019-05-23 | 2020-11-26 | University Of Maryland, Baltimore | Live attenuated non-transmissible vaccines |
| AU2020288624B2 (en) | 2019-06-04 | 2025-09-25 | Cocoon Biotech Inc. | Silk-based products, formulations, and methods of use |
| WO2021107500A1 (ko) | 2019-11-29 | 2021-06-03 | 주식회사 지니스 | 혈중 암모니아 수치 저하능을 갖는 균주 및 이를 포함하는 신경세포 보호용 조성물 |
| CN112924607A (zh) * | 2019-12-05 | 2021-06-08 | 湖北远大生物技术有限公司 | 一种同时检测酶促反应液中α-酮戊二酸和L-谷氨酸的方法 |
| CN115298308A (zh) | 2020-03-20 | 2022-11-04 | 同生运营公司 | 经工程化以减轻高苯丙氨酸血症的微生物 |
| WO2022120028A2 (en) | 2020-12-02 | 2022-06-09 | Synlogic Operating Company, Inc. | Engineered microorganisms |
| IL304020A (en) * | 2020-12-30 | 2023-08-01 | Eligo Bioscience | Microbiome modulation of a host by delivery of dna payloads with minimized spread |
| EP4436407A1 (en) | 2021-11-22 | 2024-10-02 | Solarea Bio, Inc. | Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause |
| US20230190834A1 (en) | 2021-12-21 | 2023-06-22 | Solarea Bio, Inc. | Immunomodulatory compositions comprising microbial entities |
| KR102853096B1 (ko) * | 2022-03-18 | 2025-09-02 | 씨제이제일제당 주식회사 | 카르바모일 인산 합성효소의 활성이 약화된 l-아미노산을 생산하는 미생물 및 이를 이용한 l-아미노산 생산 방법 |
| CN115960807A (zh) * | 2022-11-29 | 2023-04-14 | 深圳先进技术研究院 | 一种厌氧高产l-精氨酸工程菌及其制备方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9107305D0 (en) | 1991-04-08 | 1991-05-22 | Unilever Plc | Probiotic |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| US6203797B1 (en) | 1998-01-06 | 2001-03-20 | Stephen C. Perry | Dietary supplement and method for use as a probiotic, for alleviating the symptons associated with irritable bowel syndrome |
| EP1135461A4 (en) | 1998-12-02 | 2003-03-26 | Univ Boston | GEN NETWORKS FOR CONTROLLING GENE EXPRESSION |
| EP1034787A1 (en) | 1999-03-11 | 2000-09-13 | Société des Produits Nestlé S.A. | Lactobacillus strains preventing diarrhea caused by pathogenic bacteria |
| JP4682454B2 (ja) * | 2000-06-28 | 2011-05-11 | 味の素株式会社 | 新規変異型ｎ−アセチルグルタミン酸合成酵素及びｌ−アルギニンの製造法 |
| DE10101793A1 (de) * | 2001-01-17 | 2002-08-01 | Manfred Nilius | Verwendung von SLPI zur Behandlung chronisch-entzündlicher Darmerkrankungen |
| US7731976B2 (en) | 2003-08-29 | 2010-06-08 | Cobb And Company, Llp | Treatment of irritable bowel syndrome using probiotic composition |
| BRPI0516176B1 (pt) * | 2004-09-28 | 2020-12-29 | Kyowa Hakko Bio Co., Ltd. | Polipeptídeo, dna, microorganismo, e, processo para produzir l-arginina, l-ornitina ou lcitrulina |
| SG11201704543XA (en) * | 2014-12-05 | 2017-07-28 | Synlogic Inc | Bacteria engineered to treat diseases associated with hyperammonemia |
-
2015
- 2015-12-04 SG SG11201704543XA patent/SG11201704543XA/en unknown
- 2015-12-04 WO PCT/US2015/064140 patent/WO2016090343A1/en not_active Ceased
- 2015-12-04 SG SG10202010444UA patent/SG10202010444UA/en unknown
- 2015-12-04 AU AU2015357549A patent/AU2015357549B2/en not_active Ceased
- 2015-12-04 US US14/960,333 patent/US9487764B2/en active Active
- 2015-12-04 BR BR112017011923A patent/BR112017011923A2/pt not_active Application Discontinuation
- 2015-12-04 JP JP2017548375A patent/JP6768689B2/ja not_active Expired - Fee Related
- 2015-12-04 KR KR1020177018338A patent/KR102493174B1/ko active Active
- 2015-12-04 MX MX2017007148A patent/MX383245B/es unknown
- 2015-12-04 CA CA2969724A patent/CA2969724A1/en not_active Abandoned
-
2017
- 2017-06-01 IL IL252627A patent/IL252627B/en active IP Right Grant
- 2017-06-05 MX MX2021006581A patent/MX2021006581A/es unknown
-
2020
- 2020-10-19 IL IL278150A patent/IL278150A/en unknown
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