JP2022530503A5 - - Google Patents
Info
- Publication number
- JP2022530503A5 JP2022530503A5 JP2021563687A JP2021563687A JP2022530503A5 JP 2022530503 A5 JP2022530503 A5 JP 2022530503A5 JP 2021563687 A JP2021563687 A JP 2021563687A JP 2021563687 A JP2021563687 A JP 2021563687A JP 2022530503 A5 JP2022530503 A5 JP 2022530503A5
- Authority
- JP
- Japan
- Prior art keywords
- gene encoding
- promoter
- operably linked
- pharmaceutical composition
- genetically modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962840281P | 2019-04-29 | 2019-04-29 | |
| US62/840,281 | 2019-04-29 | ||
| US201962946785P | 2019-12-11 | 2019-12-11 | |
| US62/946,785 | 2019-12-11 | ||
| PCT/US2020/030468 WO2020223345A1 (en) | 2019-04-29 | 2020-04-29 | Enumeration of genetically engineered microorganisms by live cell counting techniques |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022530503A JP2022530503A (ja) | 2022-06-29 |
| JP2022530503A5 true JP2022530503A5 (https=) | 2023-05-12 |
Family
ID=70805206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021563687A Withdrawn JP2022530503A (ja) | 2019-04-29 | 2020-04-29 | 遺伝子操作された微生物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220257732A1 (https=) |
| EP (1) | EP3963046A1 (https=) |
| JP (1) | JP2022530503A (https=) |
| KR (1) | KR20220003030A (https=) |
| WO (1) | WO2020223345A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116847860A (zh) | 2020-12-31 | 2023-10-03 | 同生运营公司 | 经工程化以减轻高苯丙氨酸血症的微生物 |
| CN119162073A (zh) * | 2024-11-01 | 2024-12-20 | 湖南省微生物研究院 | 一株柠檬酸杆菌基因工程菌株及其构建方法和应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9107305D0 (en) | 1991-04-08 | 1991-05-22 | Unilever Plc | Probiotic |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| US6203797B1 (en) | 1998-01-06 | 2001-03-20 | Stephen C. Perry | Dietary supplement and method for use as a probiotic, for alleviating the symptons associated with irritable bowel syndrome |
| EP1034787A1 (en) | 1999-03-11 | 2000-09-13 | Société des Produits Nestlé S.A. | Lactobacillus strains preventing diarrhea caused by pathogenic bacteria |
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| US7731976B2 (en) | 2003-08-29 | 2010-06-08 | Cobb And Company, Llp | Treatment of irritable bowel syndrome using probiotic composition |
| US9084434B2 (en) | 2006-09-27 | 2015-07-21 | Little Calumet Holdings Llc | Probiotic oral dosage forms |
| SG11201704543XA (en) | 2014-12-05 | 2017-07-28 | Synlogic Inc | Bacteria engineered to treat diseases associated with hyperammonemia |
| JP7095993B2 (ja) | 2015-03-02 | 2022-07-05 | シンロジック オペレーティング カンパニー インコーポレイテッド | 消化管炎症低下および／または消化管粘膜バリア強化の利益を享受する疾患処置のために操作された細菌 |
| ES2881384T3 (es) * | 2015-05-13 | 2021-11-29 | Synlogic Operating Co Inc | Bacterias manipuladas para reducir la hiperfenilalaninemia |
| WO2016200614A2 (en) | 2015-06-10 | 2016-12-15 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with hyperammonemia |
| AU2016276973B2 (en) | 2015-06-10 | 2022-09-01 | Synlogic Operating Company, Inc. | Bacteria engineered to treat disorders involving the catabolism of a branched chain amino acid |
| WO2016210384A2 (en) | 2015-06-25 | 2016-12-29 | Synlogic, Inc. | Bacteria engineered to treat metabolic diseases |
| US20170216370A1 (en) | 2015-07-31 | 2017-08-03 | Synlogic, Inc. | Bacteria engineered to treat disorders involving propionate catabolism |
| US11273184B2 (en) | 2015-08-31 | 2022-03-15 | Synlogic Operating Company, Inc. | Bacteria engineered to treat disorders in which oxalate is detrimental |
| EP3368696A1 (en) | 2015-10-30 | 2018-09-05 | Synlogic Operating Company, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier |
| ES2925049T3 (es) | 2015-11-16 | 2022-10-13 | Synlogic Operating Co Inc | Bacterias manipuladas para reducir la hiperfenilalaninemia |
| WO2017123676A1 (en) | 2016-01-11 | 2017-07-20 | Synlogic, Inc. | Recombinant bacteria engineered to treat diseases and disorders associated with amino acid metabolism and methods of use thereof |
| WO2017123418A1 (en) | 2016-01-11 | 2017-07-20 | Synlogic, Inc. | Bacteria engineered to treat metabolic diseases |
| EP3411051A2 (en) | 2016-02-04 | 2018-12-12 | Synlogic Operating Company, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier |
| WO2017136795A1 (en) | 2016-02-04 | 2017-08-10 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with tryptophan metabolism |
| WO2017139697A1 (en) | 2016-02-10 | 2017-08-17 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with hyperammonemia |
| BR112019013863A2 (pt) | 2017-01-06 | 2020-03-03 | Synlogic Operating Company, Inc. | Micro-organismos programados para produzir moduladores imunes e terapêuticos anticâncer em células tumorais |
| CN111655841A (zh) | 2017-06-21 | 2020-09-11 | 同生运营公司 | 用于治疗紊乱的细菌 |
| JP2020527025A (ja) | 2017-07-12 | 2020-09-03 | シンロジック オペレーティング カンパニー インコーポレイテッド | 腫瘍細胞において免疫モジュレーターおよび抗がん治療剤を産生するようにプログラムされた微生物 |
-
2020
- 2020-04-29 KR KR1020217038657A patent/KR20220003030A/ko active Pending
- 2020-04-29 WO PCT/US2020/030468 patent/WO2020223345A1/en not_active Ceased
- 2020-04-29 US US17/607,248 patent/US20220257732A1/en active Pending
- 2020-04-29 EP EP20727879.7A patent/EP3963046A1/en active Pending
- 2020-04-29 JP JP2021563687A patent/JP2022530503A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6843768B2 (ja) | 高フェニルアラニン血症を低減させるように操作された細菌 | |
| JP7494345B2 (ja) | 高フェニルアラニン血症を低減させるように操作された細菌 | |
| US20210095297A1 (en) | Bacteria Engineered to Treat Diseases that Benefit from Reduced Gut Inflammation and/or Tighten Gut Mucosal Barrier | |
| JP6768689B2 (ja) | 高アンモニア血症に関連する病気を処置するために操作された細菌 | |
| EP3307870B1 (en) | Bacteria engineered to treat disorders involving the catabolism of a branched chain amino acid | |
| JP2024112925A5 (https=) | ||
| JP6817966B2 (ja) | 高アンモニア血症に関連する疾患を治療するために操作された細菌 | |
| Meng et al. | Engineered probiotics as live biotherapeutics for diagnosis and treatment of human diseases | |
| US20230092431A1 (en) | Bacteria engineered to treat disorders in which oxalate is detrimental | |
| JP2022530503A5 (https=) | ||
| US20230090705A1 (en) | Recombinant bacteria engineered to treat diseases associated with methionine metabolism and methods of use thereof | |
| WO2023044479A1 (en) | Methods for reducing hyperphenylalaninemia | |
| AU2022244381A1 (en) | Bacteria engineered to treat disorders in which oxalate is detrimental | |
| US20220257732A1 (en) | Enumeration of genetically engineered microorganisms by live cell counting techniques | |
| US20240110191A1 (en) | Engineered microorganisms | |
| JP2025534764A (ja) | 高フェニルアラニン血症を軽減するためのフェニルアラニンアンモニアリアーゼ、フェニルアラニントランスポーターおよびｌ－アミノ酸デアミナーゼを発現する組み換え細菌 | |
| TW202509224A (zh) | 具有抗腫瘤活性及更優安全性的經修飾的細菌 | |
| CN117083068A (zh) | 经工程化以治疗其中草酸盐有害的病症的细菌 |