JP2018504123A5 - - Google Patents
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- Publication number
- JP2018504123A5 JP2018504123A5 JP2017539370A JP2017539370A JP2018504123A5 JP 2018504123 A5 JP2018504123 A5 JP 2018504123A5 JP 2017539370 A JP2017539370 A JP 2017539370A JP 2017539370 A JP2017539370 A JP 2017539370A JP 2018504123 A5 JP2018504123 A5 JP 2018504123A5
- Authority
- JP
- Japan
- Prior art keywords
- collection
- biological sample
- mirna
- autism spectrum
- spectrum disorder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000523 sample Substances 0.000 claims 13
- 108091070501 miRNA Proteins 0.000 claims 12
- 239000002679 microRNA Substances 0.000 claims 12
- 239000012472 biological sample Substances 0.000 claims 11
- 238000000034 method Methods 0.000 claims 9
- 208000029560 autism spectrum disease Diseases 0.000 claims 8
- 239000007787 solid Substances 0.000 claims 5
- 238000001514 detection method Methods 0.000 claims 4
- 108091028664 Ribonucleotide Proteins 0.000 claims 3
- 238000003556 assay Methods 0.000 claims 3
- 238000002493 microarray Methods 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 239000002336 ribonucleotide Substances 0.000 claims 3
- 125000002652 ribonucleotide group Chemical group 0.000 claims 3
- 210000003296 saliva Anatomy 0.000 claims 3
- 239000011324 bead Substances 0.000 claims 2
- 238000013542 behavioral therapy Methods 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 238000007901 in situ hybridization Methods 0.000 claims 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 1
- 108700039887 Essential Genes Proteins 0.000 claims 1
- 238000000636 Northern blotting Methods 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 108020005187 Oligonucleotide Probes Proteins 0.000 claims 1
- 238000011529 RT qPCR Methods 0.000 claims 1
- 102000006382 Ribonucleases Human genes 0.000 claims 1
- 108010083644 Ribonucleases Proteins 0.000 claims 1
- 210000005013 brain tissue Anatomy 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 238000002405 diagnostic procedure Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000000975 dye Substances 0.000 claims 1
- 235000006694 eating habits Nutrition 0.000 claims 1
- 230000007613 environmental effect Effects 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 238000002483 medication Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 239000013642 negative control Substances 0.000 claims 1
- 239000002751 oligonucleotide probe Substances 0.000 claims 1
- 230000008520 organization Effects 0.000 claims 1
- 238000003752 polymerase chain reaction Methods 0.000 claims 1
- 239000013641 positive control Substances 0.000 claims 1
- 238000011002 quantification Methods 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562106107P | 2015-01-21 | 2015-01-21 | |
| US62/106,107 | 2015-01-21 | ||
| US201562263467P | 2015-12-04 | 2015-12-04 | |
| US62/263,467 | 2015-12-04 | ||
| PCT/US2016/014182 WO2016118662A1 (en) | 2015-01-21 | 2016-01-20 | Identification of epigenetic biomarkers in the saliva of children with autism spectrum disorder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018504123A JP2018504123A (ja) | 2018-02-15 |
| JP2018504123A5 true JP2018504123A5 (enExample) | 2019-02-28 |
Family
ID=56417707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017539370A Pending JP2018504123A (ja) | 2015-01-21 | 2016-01-20 | 自閉症スペクトル障害を有する児童の唾液中のエピジェネティックバイオマーカーの同定 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20180171406A1 (enExample) |
| EP (1) | EP3247798A4 (enExample) |
| JP (1) | JP2018504123A (enExample) |
| CA (1) | CA2974191A1 (enExample) |
| WO (1) | WO2016118662A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018237366B2 (en) * | 2017-03-21 | 2022-12-08 | Penn State Research Foundation | Analysis of autism spectrum disorder |
| AU2018239339A1 (en) * | 2017-03-23 | 2019-10-03 | Penn State Research Foundation | Method for diagnosing or monitoring conditions characterized by abnormal temporal variations method of normalizing epigenetic data to compensate for temporal variations |
| AU2018240473B2 (en) | 2017-03-23 | 2023-12-14 | Penn State Research Foundation | Analysis and prediction of traumatic brain injury and concusion symptoms |
| EP4162082A1 (en) * | 2020-06-04 | 2023-04-12 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Methods for diagnosing and treating autism |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2152898A2 (en) * | 2007-05-18 | 2010-02-17 | Karolinska Institutet Innovations AB | Microrna molecules associated with inflammatory skin disorders |
| US20090099034A1 (en) * | 2007-06-07 | 2009-04-16 | Wisconsin Alumni Research Foundation | Reagents and Methods for miRNA Expression Analysis and Identification of Cancer Biomarkers |
| WO2011079299A1 (en) * | 2009-12-23 | 2011-06-30 | The George Washington University | Compositions and methods for identifying autism spectrum disorders |
-
2016
- 2016-01-20 CA CA2974191A patent/CA2974191A1/en not_active Abandoned
- 2016-01-20 US US15/545,093 patent/US20180171406A1/en not_active Abandoned
- 2016-01-20 EP EP16740704.8A patent/EP3247798A4/en not_active Withdrawn
- 2016-01-20 JP JP2017539370A patent/JP2018504123A/ja active Pending
- 2016-01-20 WO PCT/US2016/014182 patent/WO2016118662A1/en not_active Ceased
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