JP2018504119A5 - - Google Patents
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- Publication number
- JP2018504119A5 JP2018504119A5 JP2017538629A JP2017538629A JP2018504119A5 JP 2018504119 A5 JP2018504119 A5 JP 2018504119A5 JP 2017538629 A JP2017538629 A JP 2017538629A JP 2017538629 A JP2017538629 A JP 2017538629A JP 2018504119 A5 JP2018504119 A5 JP 2018504119A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleotide sequence
- rotavirus
- nucleic acid
- rotavirus protein
- sequence encoding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 95
- 108020004707 nucleic acids Proteins 0.000 claims 94
- 102000039446 nucleic acids Human genes 0.000 claims 94
- 108700010850 rotavirus proteins Proteins 0.000 claims 86
- 239000002773 nucleotide Substances 0.000 claims 71
- 125000003729 nucleotide group Chemical group 0.000 claims 71
- 238000000034 method Methods 0.000 claims 43
- 101000742334 Bdellovibrio phage phiMH2K Replication-associated protein VP4 Proteins 0.000 claims 42
- 101000852023 Halorubrum pleomorphic virus 1 Envelope protein Proteins 0.000 claims 42
- 210000004027 cell Anatomy 0.000 claims 42
- 101710138767 Non-structural glycoprotein 4 Proteins 0.000 claims 29
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 29
- 102100031056 Serine protease 57 Human genes 0.000 claims 20
- 101710197596 Serine protease 57 Proteins 0.000 claims 20
- 101710081079 Minor spike protein H Proteins 0.000 claims 16
- 241000196324 Embryophyta Species 0.000 claims 15
- 239000002245 particle Substances 0.000 claims 6
- 101000996791 Banna virus (strain Indonesia/JKT-6423/1980) Non-structural protein 2 Proteins 0.000 claims 5
- 101001069760 Eumenes pomiformis Venom peptide 6 Proteins 0.000 claims 5
- 241000723655 Cowpea mosaic virus Species 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 3
- 241000238631 Hexapoda Species 0.000 claims 2
- 241000702670 Rotavirus Species 0.000 claims 2
- 239000003623 enhancer Substances 0.000 claims 2
- 238000003306 harvesting Methods 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 210000004962 mammalian cell Anatomy 0.000 claims 2
- 241000207746 Nicotiana benthamiana Species 0.000 claims 1
- 206010067470 Rotavirus infection Diseases 0.000 claims 1
- 108010067390 Viral Proteins Proteins 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000036039 immunity Effects 0.000 claims 1
- 239000000419 plant extract Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562106941P | 2015-01-23 | 2015-01-23 | |
| US62/106,941 | 2015-01-23 | ||
| PCT/CA2016/050043 WO2016115630A1 (en) | 2015-01-23 | 2016-01-21 | Rotavirus-like particle production in plants |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018504119A JP2018504119A (ja) | 2018-02-15 |
| JP2018504119A5 true JP2018504119A5 (https=) | 2019-02-21 |
| JP6841762B2 JP6841762B2 (ja) | 2021-03-10 |
Family
ID=56416224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017538629A Expired - Fee Related JP6841762B2 (ja) | 2015-01-23 | 2016-01-21 | 植物中でのロタウイルス様粒子産生 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US10287555B2 (https=) |
| EP (1) | EP3256575B1 (https=) |
| JP (1) | JP6841762B2 (https=) |
| KR (1) | KR20170104595A (https=) |
| CN (1) | CN107208072A (https=) |
| AU (1) | AU2016208999A1 (https=) |
| BR (1) | BR112017014160A2 (https=) |
| CA (1) | CA2974438A1 (https=) |
| EA (1) | EA201791683A1 (https=) |
| ES (1) | ES2826402T3 (https=) |
| HK (1) | HK1245333A1 (https=) |
| IL (1) | IL253040A0 (https=) |
| MX (1) | MX2017009568A (https=) |
| PH (1) | PH12017501330A1 (https=) |
| SG (1) | SG11201705991XA (https=) |
| WO (1) | WO2016115630A1 (https=) |
| ZA (1) | ZA201705555B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019018768A1 (en) | 2017-07-20 | 2019-01-24 | Spogen Biotech Inc. | BIOACTIVE POLYPEPTIDES FOR PLANT PROTECTION, GROWTH AND PRODUCTIVITY ENHANCEMENTS |
| JP2022521217A (ja) * | 2019-02-19 | 2022-04-06 | メディカゴ インコーポレイテッド | ロタウイルスｖｐ７融合タンパク質およびそれらを含むロタウイルス様粒子 |
| KR102647829B1 (ko) * | 2020-04-22 | 2024-03-14 | 포항공과대학교 산학협력단 | 삼량체를 형성하는 코로나-19 바이러스 (COVID-19, Coronavirus Disease 2019)의 재조합 스파이크 단백질 및 식물에서의 상기 재조합 스파이크 단백질의 대량 생산 방법과 이를 기반으로하는 백신조성물 제조 방법 |
| CN112251461B (zh) * | 2020-10-22 | 2022-08-23 | 植链(上海)生物科技有限公司 | 一种采用本氏烟作为生物反应器制备的轮状病毒疫苗及其制备方法和应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428147A (en) | 1983-04-15 | 1995-06-27 | Mycogen Plant Science, Inc. | Octopine T-DNA promoters |
| EP0152295B1 (en) | 1984-02-09 | 1991-03-20 | Royal Children's Hospital Research Foundation | Live attenuated human rotavirus vaccine and preparation thereof |
| US4636385A (en) | 1985-02-15 | 1987-01-13 | The Wistar Institute Of Anatomy & Biology | Vaccine, method for its preparation, and use thereof in vaccinating humans against rotavirus infection |
| US4751080A (en) | 1985-08-26 | 1988-06-14 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against rotavirus diseases |
| US4704275A (en) | 1985-08-26 | 1987-11-03 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against rotavirus diseases |
| US4927628A (en) | 1987-09-21 | 1990-05-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against rotavirus diseases and method of preparing same |
| KR0171434B1 (ko) | 1990-11-16 | 1999-02-01 | 윌리엄 케이. 슈버트 | 인체 로타바이러스, 백신 및 방법 |
| WO1997000088A2 (en) * | 1995-06-14 | 1997-01-03 | Baylor College Of Medicine | Rotavirus enterotoxin nsp4 and methods of using same |
| US7422747B2 (en) * | 1997-10-07 | 2008-09-09 | Loma Linda University | Transgenic plant-based vaccines |
| US20050186219A1 (en) | 1997-10-07 | 2005-08-25 | Langridge William H. | Transgenic plant-based vaccines |
| US7125978B1 (en) | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
| US6867353B2 (en) | 2000-02-12 | 2005-03-15 | Exploregen Inc. | Production method of recombinant rotavirus structural proteins and vaccine composition |
| FR2806087B1 (fr) | 2000-03-07 | 2002-10-18 | Agronomique Inst Nat Rech | Particules pseudovirales de rotavirus et leur utilisation pour vectoriser des proteines ou des acides nucleiques |
| CA2427809A1 (en) * | 2000-11-03 | 2002-05-10 | Baylor College Of Medicine | Rotavirus enterotoxin nsp4 and methods of using same |
| ES2514316T3 (es) | 2005-11-22 | 2014-10-28 | Novartis Vaccines And Diagnostics, Inc. | Partículas similares a virus (VLPs) de Norovirus y Sapovirus |
| CA2651907C (en) | 2006-05-22 | 2016-12-20 | Plant Bioscience Limited | Bipartite system, method and composition for the constitutive and inducible expression of high levels of foreign proteins in plants |
| WO2009076778A1 (en) | 2007-11-27 | 2009-06-25 | Medicago Inc. | Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin |
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| GB0800272D0 (en) | 2008-01-08 | 2008-02-13 | Plant Bioscience Ltd | Protein expression systems |
| EP2297186B1 (en) | 2008-05-29 | 2018-08-29 | The Government of The United States of America, as represented by the Secretary, Department of Health and Human Services, | Expression and assembly of human group c rotavirus-like particles and uses thereof |
| WO2012058762A1 (en) | 2010-11-04 | 2012-05-10 | Medicago Inc. | Plant expression system |
| KR101963792B1 (ko) * | 2011-06-13 | 2019-07-31 | 메디카고 인코포레이티드 | 식물에서 광견병 바이러스 유사 입자 생성 |
| EA032089B1 (ru) * | 2012-05-11 | 2019-04-30 | Медикаго Инк. | Получение ротавирус-подобных частиц в растениях |
-
2016
- 2016-01-21 AU AU2016208999A patent/AU2016208999A1/en not_active Abandoned
- 2016-01-21 HK HK18104978.8A patent/HK1245333A1/zh unknown
- 2016-01-21 CN CN201680006015.6A patent/CN107208072A/zh active Pending
- 2016-01-21 EP EP16739705.8A patent/EP3256575B1/en not_active Not-in-force
- 2016-01-21 CA CA2974438A patent/CA2974438A1/en not_active Abandoned
- 2016-01-21 US US15/545,362 patent/US10287555B2/en active Active
- 2016-01-21 ES ES16739705T patent/ES2826402T3/es active Active
- 2016-01-21 SG SG11201705991XA patent/SG11201705991XA/en unknown
- 2016-01-21 BR BR112017014160-4A patent/BR112017014160A2/pt not_active Application Discontinuation
- 2016-01-21 WO PCT/CA2016/050043 patent/WO2016115630A1/en not_active Ceased
- 2016-01-21 EA EA201791683A patent/EA201791683A1/ru unknown
- 2016-01-21 JP JP2017538629A patent/JP6841762B2/ja not_active Expired - Fee Related
- 2016-01-21 MX MX2017009568A patent/MX2017009568A/es unknown
- 2016-01-21 KR KR1020177023021A patent/KR20170104595A/ko not_active Withdrawn
-
2017
- 2017-06-20 IL IL253040A patent/IL253040A0/en unknown
- 2017-07-21 PH PH12017501330A patent/PH12017501330A1/en unknown
- 2017-08-16 ZA ZA2017/05555A patent/ZA201705555B/en unknown
-
2019
- 2019-03-29 US US16/369,703 patent/US20190345454A1/en not_active Abandoned
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